Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
Chain A, Membrane lipoprotein tmpC | 0 | 0 | 1 | 1 |
Chain A, Membrane lipoprotein tmpC | 0 | 0 | 1 | 1 |
Chain A, Membrane lipoprotein tmpC | 0 | 0 | 1 | 1 |
Chain A, Structure of PAE2307 in complex with adenosine | 0 | 0 | 1 | 1 |
Chain B, Structure of PAE2307 in complex with adenosine | 0 | 0 | 1 | 1 |
Chain A, ADENOSINE RECEPTOR A2A | 0 | 1 | 0 | 1 |
Chain A, ADENOSINE RECEPTOR A2A | 0 | 1 | 0 | 1 |
Chain A, tRNA (guanine-N(1)-)-methyltransferase | 0 | 0 | 1 | 1 |
Chain A, Uncharacterized protein MJ0883 | 0 | 0 | 1 | 1 |
AR protein | 5 | 0 | 0 | 5 |
signal transducer and activator of transcription 6, interleukin-4 induced | 1 | 0 | 0 | 1 |
regulator of G-protein signaling 4 | 3 | 0 | 0 | 3 |
glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
estrogen nuclear receptor alpha | 6 | 0 | 0 | 6 |
NPYLR7B | 0 | 0 | 1 | 1 |
arylsulfatase A | 3 | 0 | 0 | 3 |
IDH1 | 1 | 0 | 0 | 1 |
Histone H2A.x | 1 | 0 | 0 | 1 |
glycogen synthase kinase-3 beta isoform 1 | 0 | 0 | 1 | 1 |
mitogen-activated protein kinase 1 | 2 | 0 | 0 | 2 |
flap endonuclease 1 | 2 | 0 | 0 | 2 |
nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
high affinity choline transporter 1 isoform a | 0 | 1 | 0 | 1 |
Sodium/nucleoside cotransporter 1 | 0 | 2 | 0 | 2 |
Calcium dependent protein kinase | 0 | 1 | 0 | 1 |
Mitogen-activated protein kinase kinase kinase 7 | 0 | 0 | 1 | 1 |
Sodium/nucleoside cotransporter 2 | 0 | 2 | 0 | 2 |
Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
Purine nucleoside phosphorylase | 0 | 1 | 0 | 1 |
Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
Phosphoglycerate kinase 1 | 0 | 1 | 0 | 1 |
Adenosine deaminase | 0 | 0 | 0 | 1 |
Avidin | 0 | 0 | 1 | 1 |
Adenosine deaminase | 0 | 0 | 0 | 1 |
Glyceraldehyde-3-phosphate dehydrogenase | 0 | 2 | 0 | 2 |
Receptor tyrosine-protein kinase erbB-2 | 0 | 1 | 0 | 1 |
Insulin receptor | 0 | 0 | 0 | 1 |
Phosphoglycerate kinase 2 | 0 | 1 | 0 | 1 |
Heat shock protein HSP 90-alpha | 0 | 1 | 1 | 2 |
Platelet-derived growth factor receptor beta | 0 | 0 | 0 | 1 |
Adenosine receptor A3 | 0 | 2 | 2 | 5 |
Heat shock 70 kDa protein 1A | 0 | 1 | 0 | 1 |
Heat shock cognate 71 kDa protein | 0 | 0 | 1 | 1 |
Fibroblast growth factor receptor 1 | 0 | 0 | 0 | 1 |
Inosine-5'-monophosphate dehydrogenase 2 | 0 | 1 | 0 | 1 |
Endoplasmin | 0 | 1 | 1 | 2 |
Glutamate receptor 2 | 1 | 0 | 0 | 1 |
Inosine-5'-monophosphate dehydrogenase 1 | 0 | 1 | 0 | 1 |
Fibroblast growth factor receptor 2 | 0 | 0 | 0 | 1 |
Fibroblast growth factor receptor 4 | 0 | 0 | 0 | 1 |
Fibroblast growth factor receptor 3 | 0 | 0 | 0 | 1 |
Streptavidin | 0 | 0 | 1 | 1 |
Adenosylhomocysteinase | 0 | 0 | 0 | 1 |
Adenosine receptor A1 | 0 | 1 | 1 | 2 |
Adenosine receptor A3 | 0 | 1 | 0 | 1 |
Adenosine receptor A2a | 0 | 1 | 2 | 4 |
Adenosine receptor A2b | 0 | 0 | 1 | 2 |
Adenosine receptor A2b | 0 | 1 | 1 | 2 |
Adenylate kinase 2, mitochondrial | 0 | 1 | 0 | 1 |
Adenosine receptor A1 | 0 | 2 | 2 | 5 |
Adenosine receptor A2a | 0 | 1 | 1 | 2 |
Adenylate kinase isoenzyme 1 | 0 | 1 | 0 | 1 |
Phosphatidylinositol 4-kinase alpha | 0 | 2 | 0 | 3 |
Adenosine receptor A1 | 0 | 0 | 1 | 1 |
Adenosine kinase | 0 | 0 | 0 | 1 |
Adenosine deaminase | 0 | 0 | 0 | 1 |
Equilibrative nucleoside transporter 2 | 0 | 2 | 0 | 2 |
Phosphatidylinositol 4-kinase type 2-beta | 0 | 2 | 0 | 3 |
Histone-lysine N-methyltransferase, H3 lysine-79 specific | 0 | 1 | 0 | 1 |
Equilibrative nucleoside transporter 1 | 0 | 2 | 0 | 2 |
Phosphatidylinositol 4-kinase type 2-alpha | 0 | 2 | 0 | 3 |
Solute carrier family 28 member 3 | 0 | 2 | 0 | 2 |
Adenosine kinase | 0 | 1 | 0 | 2 |
Phosphatidylinositol 4-kinase beta | 0 | 2 | 0 | 3 |
5-methylthioadenosine/S-adenosylhomocysteine deaminase | 0 | 0 | 0 | 1 |
Adenosine transporter 1 | 0 | 0 | 0 | 1 |
interleukin 8 | 1 | 0 | 0 | 1 |
phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
progesterone receptor | 2 | 0 | 0 | 2 |
estrogen-related nuclear receptor alpha | 1 | 0 | 0 | 1 |
G | 2 | 0 | 0 | 2 |
cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
alpha-galactosidase | 1 | 0 | 0 | 1 |
euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
cytochrome P450 2C19 precursor | 2 | 0 | 0 | 2 |
geminin | 2 | 0 | 0 | 2 |
DNA polymerase kappa isoform 1 | 2 | 0 | 0 | 2 |
cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
lamin isoform A-delta10 | 4 | 0 | 0 | 4 |
Solute carrier family 22 member 1 | 0 | 2 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
Solute carrier family 22 member 2 | 0 | 4 | 0 | 5 |
Solute carrier family 22 member 1 | 0 | 6 | 0 | 7 |
ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
Solute carrier family 22 member 6 | 0 | 2 | 0 | 2 |
Solute carrier family 22 member 2 | 0 | 2 | 0 | 2 |
cGMP-specific 3',5'-cyclic phosphodiesterase | 0 | 1 | 0 | 1 |
Bile salt export pump | 0 | 5 | 0 | 5 |
Interferon beta | 2 | 0 | 0 | 2 |
HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
Cellular tumor antigen p53 | 1 | 0 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 2 |
ATP-dependent translocase ABCB1 | 0 | 3 | 1 | 11 |
Cytochrome P450 3A4 | 0 | 2 | 0 | 2 |
Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
Cytochrome P450 2C9 | 0 | 3 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
Potassium-transporting ATPase alpha chain 1 | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
Histamine H2 receptor | 0 | 4 | 0 | 4 |
Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
Histamine H1 receptor | 0 | 0 | 1 | 1 |
Histamine H2 receptor | 0 | 2 | 1 | 3 |
Potassium-transporting ATPase subunit beta | 0 | 1 | 0 | 1 |
Cytochrome P450 2J2 | 0 | 3 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
Aldehyde oxidase | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 1 | 0 | 5 | 0 | 5 |
Multidrug and toxin extrusion protein 2 | 0 | 2 | 0 | 2 |
Solute carrier family 22 member 8 | 0 | 2 | 0 | 3 |
GABA theta subunit | 1 | 0 | 0 | 1 |
Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
Multidrug and toxin extrusion protein 1 | 0 | 2 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
Histamine H4 receptor | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 11 | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 2 | 0 | 5 | 0 | 5 |
Solute carrier family 22 member 4 | 0 | 2 | 0 | 2 |
Solute carrier family 22 member 8 | 0 | 2 | 0 | 2 |
cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
acetylcholinesterase | 1 | 0 | 0 | 1 |
cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
nonstructural protein 1 | 1 | 0 | 0 | 1 |
activating transcription factor 6 | 2 | 0 | 0 | 2 |
Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
potassium voltage-gated channel subfamily H member 2 isoform d | 3 | 0 | 0 | 3 |
importin subunit beta-1 isoform 1 | 1 | 0 | 0 | 1 |
snurportin-1 | 1 | 0 | 0 | 1 |
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 2 | 0 | 0 | 2 |
histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 4 | 0 | 4 |
5-hydroxytryptamine receptor 7 | 0 | 2 | 0 | 2 |
Spike glycoprotein | 2 | 0 | 0 | 2 |
Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 4 | 0 | 4 |
Potassium voltage-gated channel subfamily H member 2 | 0 | 4 | 0 | 4 |
Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 4 | 0 | 4 |
Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 4 | 0 | 4 |
TDP1 protein | 3 | 0 | 0 | 3 |
EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
Potassium voltage-gated channel subfamily A member 5 | 0 | 1 | 0 | 1 |
Potassium voltage-gated channel subfamily A member 1 | 0 | 1 | 0 | 1 |
Sodium channel protein type 5 subunit alpha | 0 | 2 | 0 | 2 |
Potassium voltage-gated channel subfamily D member 2 | 0 | 1 | 0 | 1 |
GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
Sterol O-acyltransferase 1 | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 3 | 0 | 1 | 0 | 1 |
Acetylcholinesterase | 0 | 2 | 0 | 2 |
Acetylcholinesterase | 0 | 1 | 0 | 1 |
DNA (cytosine-5)-methyltransferase 1 | 0 | 1 | 0 | 1 |
Sterol O-acyltransferase 1 | 0 | 1 | 0 | 1 |
DNA (cytosine-5)-methyltransferase 3-like | 0 | 1 | 0 | 1 |
DNA (cytosine-5)-methyltransferase 3A | 0 | 1 | 0 | 1 |
glp-1 receptor, partial | 1 | 0 | 0 | 1 |
thioredoxin reductase | 1 | 0 | 0 | 1 |
nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
pregnane X nuclear receptor | 1 | 0 | 0 | 1 |
glucocerebrosidase | 1 | 0 | 0 | 1 |
peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
huntingtin isoform 2 | 1 | 0 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
Bile salt export pump | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
Albumin | 0 | 0 | 1 | 1 |
Glycoprotein | 0 | 1 | 0 | 1 |
Muscarinic acetylcholine receptor M2 | 0 | 0 | 1 | 1 |
Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
Cytochrome P450 2C8 | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 1A | 0 | 2 | 0 | 2 |
Catechol O-methyltransferase | 0 | 1 | 0 | 1 |
Potassium voltage-gated channel subfamily A member 3 | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
5-hydroxytryptamine receptor 1B | 0 | 2 | 0 | 2 |
Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
Delta-type opioid receptor | 0 | 1 | 0 | 1 |
Multidrug resistance-associated protein 1 | 0 | 2 | 1 | 4 |
Mu-type opioid receptor | 0 | 1 | 0 | 1 |
D(3) dopamine receptor | 0 | 2 | 0 | 2 |
Kappa-type opioid receptor | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
D(2) dopamine receptor | 0 | 1 | 0 | 1 |
Ataxin-2 | 1 | 0 | 0 | 1 |
Chloroquine resistance transporter | 0 | 1 | 0 | 1 |
Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 1 | 2 |
Solute carrier organic anion transporter family member 1B1 | 0 | 2 | 0 | 2 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |