Superior Vena Cava Obstruction

A condition that occurs when the obstruction of the thin-walled SUPERIOR VENA CAVA interrupts blood flow from the head, upper extremities, and thorax to the RIGHT ATRIUM. Obstruction can be caused by NEOPLASMS; THROMBOSIS; ANEURYSM; or external compression. The syndrome is characterized by swelling and/or CYANOSIS of the face, neck, and upper arms.

Synonym
Superior Vena Cava Thrombosis
Superior Vena Cava Syndrome
Superior Vena Cava Obstruction

Excerpt	Reference
"Superior vena cava syndrome is a rare, life-threatening clinical entity associated with occlusion of venous outflow from the head, neck, and upper extremities; this syndrome produces facial edema, cyanosis, dyspnea, and prominent neck veins, and is usually caused by intrathoracic neoplasms."	( Abulafia, O; Sherer, DM, 1995)
"Upper arm edema and superior vena cava syndrome are the most common presentation of this subclavian thrombosis associated with pacemakers."	( Ciocon, JO; Galindo-Ciocon, D, 1998)
"The superior vena cava obstruction is a relatively rare condition."	( Andrade-Filho, AS; Andrade-Souza, YM; Bandeira, ER; Figueirôa, FS; Santiago-Figueirôa, CL; Silva, AG; Silveira, DB; Souza, AP, 1998)

Excerpt	Reference
"A case of lung cancer with superior vena cava syndrome treated with internal thoracic arterial infusion of anti-cancer drugs by the implantable port system was reported with our technique."	( Hara, F; Kawai, T; Miyake, T; Nakajima, T; Shinozaki, Y; Taira, N, 1999)
"We experienced a pregnant woman with superior vena cava syndrome at 15 weeks of pregnancy who was diagnosed with primary mediastinal large B-cell lymphoma and given chemotherapy."	( Hashimoto, Y; Nakamoto, S; Omura, H; Tanaka, T; Tokuyasu, Y, 2019)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	18 (10.00)	23.3326
1990's	46 (25.56)	12.5806
2000's	46 (25.56)	18.1394
2010's	57 (31.67)	28.8240
2020's	13 (7.22)	9.53

Drug	Relationship Strength	Studies
adenine	low	1
citric acid, anhydrous	low	1
lactic acid	low	1
dimethyl sulfoxide	low	1
glycerol	low	1
dalteparin	low	3
pyruvic acid	low	1
phenytoin	low	1
albendazole	low	1
aspirin	low	1
azathioprine	low	3
bupivacaine	low	1
dapsone	low	1
diethylcarbamazine	low	1
pentetic acid	low	1
fluconazole	low	1
fluorouracil	low	4
flutamide	low	1
furosemide	low	2
glyburide	low	1
ifosfamide	low	3
iohexol	low	3
iopromide	low	1
ketoconazole	low	2
mechlorethamine	low	2
mianserin	low	1
mirtazapine	low	1
prednisolone	low	13
alloxan	low	1
thyroxine	low	1
prednisone	low	6
colchicine	low	2
cytarabine	low	3
methylprednisolone	low	5
pyrroles	low	2
diatrizoate meglumine	low	2
quinazolines	low	2
dexamethasone 21-phosphate	low	1
methamphetamine	low	1
methylnitrosourea	low	1
deoxycytidine	low	1
vancomycin	low	1
megestrol	low	1
platinum	low	1
tantalum	low	1
technetium	low	2
gadolinium	low	1
camptothecin	low	2
paclitaxel	low	1
etoposide	low	9
propiconazole	low	1
itraconazole	low	1
cilazapril, anhydrous	low	1
gemcitabine	low	1
iopamidol	low	1
fluorodeoxyglucose f18	low	9
gefitinib	low	1
methotrexate	low	4
docetaxel anhydrous	low	1
technetium tc 99m pentetate	low	2
erlotinib hydrochloride	low	1
trimethoprim, sulfamethoxazole drug combination	low	1
carboplatin	low	5
arabinose	low	1
fibrin	low	1
meropenem	low	1
dactinomycin	low	1
picibanil	low	1
iothalamate meglumine	low	1
leuprolide	low	2
didimethylsulfoxide dichloroplatinum(ii)	low	1
nitinol	low	6
vitamin k semiquinone radical	low	1
rutin	low	2
amphotericin b	low	2
tranilast	low	1
rutin sulfate	low	1
dexmedetomidine	low	2
su 11248	low	2
enalapril	low	1
gadolinium dtpa	low	1
rivaroxaban	low	1
technetium tc 99m disofenin	low	1
losartan potassium	low	1
bivalirudin	low	1
atrial natriuretic factor	low	1
technetium tc 99m sestamibi	low	1
ro13-9904	low	3
sodium pertechnetate tc 99m	low	6
pci 32765	low	1
trelstar	low	1
plx4032	low	1
piperidines	low	1
natriuretic peptide, brain	low	1
dicumarol	low	1
warfarin	low	11
hirudin	low	1
technetium tc 99m sulfur colloid	low	6
lewis x antigen	low	1
hyaluronoglucosaminidase	low	1
technetium tc 99m medronate	low	2
thromboplastin	low	1
levoleucovorin	low	2
dacarbazine	low	2
ganciclovir	low	1
pemetrexed	low	1

Protein Targets (1,426)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	18	0	0	18
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
RAR-related orphan receptor gamma	25	0	0	25
TDP1 protein	30	0	0	30
AR protein	34	0	0	34
nuclear receptor subfamily 1, group I, member 3	26	0	0	26
cytochrome P450 family 3 subfamily A polypeptide 4	21	0	0	21
glucocorticoid receptor [Homo sapiens]	29	0	0	29
estrogen-related nuclear receptor alpha	32	0	0	32
pregnane X nuclear receptor	27	0	0	27
estrogen nuclear receptor alpha	42	0	0	42
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	20	0	0	20
nuclear factor erythroid 2-related factor 2 isoform 2	12	0	0	12
heat shock protein beta-1	7	0	0	7
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
lamin isoform A-delta10	27	0	0	27
Voltage-dependent calcium channel gamma-2 subunit	16	0	0	16
Bile salt export pump	0	38	0	38
Cyclin-dependent kinase 1	0	1	4	5
Heat shock protein HSP 90-beta	0	1	0	1
Glutamate receptor 2	16	0	0	16
Xanthine dehydrogenase/oxidase	0	2	0	2
TAR DNA-binding protein 43	5	0	0	5
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	3	2	5
ATPase family AAA domain-containing protein 5	16	0	0	16
Ataxin-2	18	0	0	18
Chain A, Beta-lactamase	8	0	0	8
Luciferase	8	0	0	8
glp-1 receptor, partial	6	0	0	6
hypoxia-inducible factor 1 alpha subunit	11	0	0	11
ATAD5 protein, partial	10	0	0	10
Fumarate hydratase	11	0	0	11
GLI family zinc finger 3	26	0	0	26
caspase 7, apoptosis-related cysteine protease	6	0	0	6
progesterone receptor	16	0	0	16
retinoic acid nuclear receptor alpha variant 1	27	0	0	27
retinoid X nuclear receptor alpha	20	0	0	20
farnesoid X nuclear receptor	17	0	0	17
polyprotein	11	0	0	11
67.9K protein	13	0	0	13
peroxisome proliferator activated receptor gamma	18	0	0	18
vitamin D (1,25- dihydroxyvitamin D3) receptor	13	0	0	13
caspase-3	6	0	0	6
IDH1	8	0	0	8
euchromatic histone-lysine N-methyltransferase 2	25	0	0	25
aryl hydrocarbon receptor	14	0	0	14
v-jun sarcoma virus 17 oncogene homolog (avian)	13	0	0	13
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
Histone H2A.x	10	0	0	10
cellular tumor antigen p53 isoform a	10	0	0	10
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
chromobox protein homolog 1	19	0	0	19
transcriptional regulator ERG isoform 3	4	0	0	4
thyroid hormone receptor beta isoform 2	29	0	0	29
histone deacetylase 9 isoform 3	1	0	0	1
mitogen-activated protein kinase 1	5	0	0	5
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
geminin	27	0	0	27
Vif	0	0	0	1
peripheral myelin protein 22	19	0	0	19
survival motor neuron protein isoform d	11	0	0	11
muscleblind-like protein 1 isoform 1	11	0	0	11
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
neuropeptide S receptor isoform A	3	0	0	3
ATP-binding cassette sub-family C member 3	0	31	0	31
Multidrug resistance-associated protein 4	0	31	0	32
Interferon beta	26	0	0	26
Cellular tumor antigen p53	26	0	0	26
Integrin beta-3	7	2	0	9
Integrin alpha-IIb	7	1	0	8
Methionine aminopeptidase	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Inositol monophosphatase 1	7	0	0	7
Canalicular multispecific organic anion transporter 1	0	31	0	32
Chain A, Putative fructose-1,6-bisphosphate aldolase	9	0	0	9
Chain A, 2-oxoglutarate Oxygenase	10	0	0	10
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
Chain A, Xcogt	0	0	1	1
Chain A, Xcogt	0	0	1	1
Chain A, Xcogt	0	0	1	1
phosphopantetheinyl transferase	10	0	0	10
USP1 protein, partial	18	0	0	18
Microtubule-associated protein tau	11	0	0	11
Bloom syndrome protein isoform 1	11	0	0	11
vitamin D3 receptor isoform VDRA	12	0	0	12
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Chain A, HADH2 protein	8	0	0	8
Chain B, HADH2 protein	8	0	0	8
Chain A, Cruzipain	3	0	0	3
interleukin 8	9	0	0	9
GLS protein	10	0	0	10
peroxisome proliferator-activated receptor delta	19	0	0	19
tumor necrosis factor	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	26	0	0	26
Cytochrome P450 1A2	0	3	0	3
Cytochrome P450 3A4	0	11	0	13
Cytochrome P450 2D6	0	3	0	3
Cytochrome P450 2C9	0	12	0	13
Cytochrome P450 2C19	0	3	0	4
Nuclear receptor ROR-gamma	8	0	0	8
Potassium voltage-gated channel subfamily H member 2	0	7	0	7
Aurora kinase B	0	2	4	6
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	5	1	8
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	7	0	0	7
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
thioredoxin reductase	16	0	0	16
aldehyde dehydrogenase 1 family, member A1	20	0	0	20
thyroid stimulating hormone receptor	12	0	0	12
hypothetical protein, conserved	1	0	0	1
EWS/FLI fusion protein	21	0	0	21
cytochrome P450 2D6	12	0	0	12
glucocerebrosidase	3	0	0	3
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
DNA polymerase iota isoform a (long)	11	0	0	11
DNA polymerase kappa isoform 1	7	0	0	7
muscarinic acetylcholine receptor M1	7	0	0	7
lethal factor (plasmid)	5	0	0	5
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	3	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Epidermal growth factor receptor	0	11	6	17
Carbonic anhydrase 1	0	3	0	4
Carbonic anhydrase 2	0	3	1	5
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Adenosine receptor A1	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	3	2	5
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	13	2	1	16
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	1	1	2
Sigma non-opioid intracellular receptor 1	0	0	1	1
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
Chain A, Ferritin light chain	9	0	0	9
acetylcholinesterase	11	0	0	11
SMAD family member 2	4	0	0	4
SMAD family member 3	4	0	0	4
thioredoxin glutathione reductase	4	0	0	4
G	14	0	0	14
P53	1	0	0	1
arylsulfatase A	8	0	0	8
thyroid stimulating hormone receptor	8	0	0	8
activating transcription factor 6	8	0	0	8
peripheral myelin protein 22 isoform 1	8	0	0	8
hemoglobin subunit beta	3	0	0	3
cytochrome P450 3A4 isoform 1	13	0	0	13
M-phase phosphoprotein 8	6	0	0	6
Gamma-aminobutyric acid receptor subunit pi	13	1	1	15
Bile salt export pump	0	8	0	8
HLA class I histocompatibility antigen, B alpha chain	14	0	0	14
Gamma-aminobutyric acid receptor subunit beta-1	13	1	1	15
Gamma-aminobutyric acid receptor subunit delta	13	1	1	15
Gamma-aminobutyric acid receptor subunit gamma-2	13	1	1	15
Gamma-aminobutyric acid receptor subunit alpha-5	13	1	1	15
Gamma-aminobutyric acid receptor subunit alpha-3	13	1	1	15
Gamma-aminobutyric acid receptor subunit gamma-1	13	1	1	15
Gamma-aminobutyric acid receptor subunit alpha-2	13	1	1	15
Gamma-aminobutyric acid receptor subunit alpha-4	13	1	1	15
Gamma-aminobutyric acid receptor subunit gamma-3	13	1	1	15
Gamma-aminobutyric acid receptor subunit alpha-6	13	1	1	15
Gamma-aminobutyric acid receptor subunit beta-3	13	1	1	15
Gamma-aminobutyric acid receptor subunit beta-2	13	1	1	15
GABA theta subunit	13	1	1	15
Inositol hexakisphosphate kinase 1	14	0	0	14
Gamma-aminobutyric acid receptor subunit epsilon	13	1	1	15
Protein-arginine deiminase type-4	0	2	0	2
cytochrome P450 2C9, partial	14	0	0	14
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	0	2	2
Potassium channel subfamily K member 9	0	1	0	1
DNA topoisomerase	0	1	0	1
15-lipoxygenase, partial	5	0	0	5
NFKB1 protein, partial	3	0	0	3
PPM1D protein	10	0	0	10
Thrombopoietin	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
regulator of G-protein signaling 4	5	0	0	5
putative alpha-glucosidase	1	0	0	1
alpha-galactosidase	4	0	0	4
lysosomal alpha-glucosidase preproprotein	2	0	0	2
cytochrome P450 2C19 precursor	8	0	0	8
huntingtin isoform 2	7	0	0	7
ras-related protein Rab-9A	4	0	0	4
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
nuclear receptor ROR-gamma isoform 1	10	0	0	10
histone acetyltransferase KAT2A isoform 1	7	0	0	7
relaxin receptor 1 isoform 1	1	0	0	1
Telomerase reverse transcriptase	0	1	0	1
Serine/threonine-protein kinase Chk1	0	1	5	6
Histone deacetylase 3	0	2	0	2
Type-2 restriction enzyme ScaI	0	1	0	1
Deoxyribonuclease-2-alpha	0	1	0	1
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Deoxyribonuclease-1	0	1	0	1
Type-2 restriction enzyme PstI	0	1	0	1
Type-2 restriction enzyme EcoRI	0	1	0	1
Prothrombin	0	1	0	3
DNA ligase	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
DNA topoisomerase 1	0	2	1	9
DNA topoisomerase 2-alpha	0	2	5	13
Type-2 restriction enzyme BamHI	0	1	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
5-hydroxytryptamine receptor 2B	0	6	0	6
Type-2 restriction enzyme HindIII	0	1	0	1
D(1A) dopamine receptor	2	0	0	2
Histone deacetylase 4	0	2	0	2
Ribonuclease pancreatic	0	1	0	1
DNA topoisomerase 2-beta	0	1	5	13
DNA topoisomerase 1	0	1	0	2
Histone deacetylase 1	0	3	0	3
DNA topoisomerase 1	0	1	0	1
Integrase	0	3	0	3
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
DNA topoisomerase type IB small subunit	0	0	1	1
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	3	0	3
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
estrogen receptor 2 (ER beta)	17	0	0	17
histone-lysine N-methyltransferase 2A isoform 2 precursor	6	0	0	6
ATP-dependent phosphofructokinase	12	0	0	12
Liver carboxylesterase 1	0	0	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	1	0	1
thyroid hormone receptor beta isoform a	10	0	0	10
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	5	4	9
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
endonuclease IV	9	0	0	9
PAX8	0	0	0	1
pregnane X receptor	6	0	0	6
Smad3	4	0	0	4
cytochrome P450 2D6 isoform 1	4	0	0	4
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cytochrome P450 2C9 precursor	8	0	0	8
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
flap endonuclease 1	6	0	0	6
steroidogenic factor 1	0	1	0	1
caspase-1 isoform alpha precursor	3	0	0	3
Solute carrier family 22 member 3	0	3	0	3
Tubulin alpha-1A chain	0	2	2	5
Tubulin beta chain	0	2	2	4
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	3	3	8
ATP-dependent translocase ABCB1	0	5	0	5
Tubulin beta chain	0	3	3	8
ATP-dependent translocase ABCB1	0	11	1	20
Tubulin alpha-3C chain	0	3	3	8
Serine/threonine-protein kinase pim-1	0	1	4	5
ATP-dependent translocase ABCB1	0	6	0	6
Histamine H2 receptor	12	1	0	14
Tubulin alpha-1B chain	0	3	3	8
Tubulin alpha-4A chain	0	3	3	8
Tubulin beta-4B chain	0	3	3	8
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	4	3	9
Tubulin beta-2A chain	0	3	3	8
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	3	3	8
Tubulin beta-2B chain	0	3	1	6
Tubulin alpha-3E chain	0	3	3	8
Tubulin alpha-1A chain	0	3	3	8
Similar to alpha-tubulin isoform 1	0	2	1	5
Similar to alpha-tubulin isoform 1	0	2	0	4
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	3	3	8
Tubulin beta-6 chain	0	3	3	8
Tubulin beta-2B chain	0	3	3	8
Tubulin beta-1 chain	0	3	3	8
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	4	0	5
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	4	7
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	1	0	4
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	2
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Isocitrate lyase	0	1	0	1
RAD51	0	1	0	1
Caspase-7	3	0	0	3
caspase-3	3	0	0	3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Caspase-7	2	0	0	2
Spike glycoprotein	15	0	1	16
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	4	5
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	2	1	3
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
Dihydrofolate reductase	0	4	0	4
5-hydroxytryptamine receptor 6	0	7	0	8
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Transthyretin	0	2	0	3
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Platelet-activating factor receptor	1	0	0	1
Multidrug resistance-associated protein 1	0	2	0	4
Thymidine kinase 2	0	1	0	1
AAA family ATPase	0	0	0	2
Alpha-1B adrenergic receptor	0	0	1	1
Alpha-2A adrenergic receptor	0	11	1	12
Alpha-1B adrenergic receptor	0	6	1	7
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-2C adrenergic receptor	0	8	1	9
Alpha-2B adrenergic receptor	0	4	1	5
Alpha-2C adrenergic receptor	0	4	1	5
Alpha-2A adrenergic receptor	0	4	1	5
Alpha-1D adrenergic receptor	0	6	1	7
Alpha-1D adrenergic receptor	0	3	0	3
Alpha-1A adrenergic receptor	0	6	1	7
Hsf1 protein	0	0	1	1
potassium voltage-gated channel subfamily H member 2 isoform d	5	0	0	5
NAD	0	1	0	1
Cholinesterase	0	1	0	1
Urease	0	1	0	1
NAD	0	1	0	2
Mitogen-activated protein kinase 1	0	1	4	5
ATP phosphoribosyltransferase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	2	0	2
G-protein coupled receptor 35	0	2	2	4
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	2	0	2
Serum paraoxonase/arylesterase 1	0	5	0	5
Kinesin-like protein KIF11	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	2	0	2
Angiotensin-converting enzyme	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Type-2 angiotensin II receptor	0	5	0	5
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Angiotensin-converting enzyme	0	3	0	3
Solute carrier family 15 member 1	0	2	0	2
Multidrug and toxin extrusion protein 1	0	3	0	3
Angiotensin-converting enzyme 2	0	1	1	2
Receptor tyrosine-protein kinase erbB-2	0	4	3	7
Serine/threonine-protein kinase B-raf	0	2	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	2	0	0	2
Regulatory protein E2	0	0	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
DNA topoisomerase 2	0	0	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	4
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Caspase-3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2B	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
apical membrane antigen 1, AMA1	2	0	0	2
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Rap guanine nucleotide exchange factor 3	3	0	0	3
Chymotrypsinogen A	0	4	0	4
Beta-lactamase	0	3	0	3
Steroid 17-alpha-hydroxylase/17,20 lyase	0	3	0	3
Heme oxygenase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	5	0	5
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B2, mitochondrial	0	2	0	2
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	3	0	3
Cytochrome P450 144	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	3	2	5
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
14-alpha sterol demethylase	0	0	1	1
heat shock protein 90, putative	0	0	0	2
likely tRNA 2'-phosphotransferase	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
nonstructural protein 1	7	0	0	7
Vpr	1	0	0	1
Solute carrier family 22 member 8	0	0	0	1
Amyloid-beta precursor protein	1	0	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
D(1A) dopamine receptor	3	0	0	3
Cocaine esterase	0	1	0	2
Androgen receptor	0	4	0	4
Androgen receptor	0	5	0	5
Arylacetamide deacetylase	0	0	0	1
Alpha-synuclein	1	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
Carbonic anhydrase 12	0	1	0	2
Albumin	0	1	2	3
Carbonic anhydrase 3	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Carbonic anhydrase 4	0	1	0	2
Carbonic anhydrase 6	0	1	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	2
Carbonic anhydrase 7	0	1	0	2
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Cytochrome P450 2J2	0	3	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
Carbonic anhydrase 9	0	1	0	2
Carbonic anhydrase 13	0	1	0	2
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Carbonic anhydrase 14	0	1	0	2
Carbonic anhydrase 5B, mitochondrial	0	1	0	2
Thymidine kinase	0	1	0	1
ClpP	2	0	0	2
Solute carrier family 22 member 1	0	3	0	4
POU domain, class 2, transcription factor 2	0	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	0	0	2
Leukotriene C4 synthase	0	0	2	2
epidermal growth factor receptor isoform a precursor	1	1	0	2
tyrosine-protein kinase Yes	5	0	0	5
Bone morphogenetic protein receptor type-1B	0	0	4	4
Cell division cycle 7-related protein kinase	0	0	3	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	2	2	4
Serine/threonine-protein kinase PLK4	0	1	4	5
Serine/threonine-protein kinase 25	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	2	2
Pyridoxal kinase	0	0	4	4
Citron Rho-interacting kinase	0	0	4	4
Serine/threonine-protein kinase RIO3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 7	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	2	2
Peripheral plasma membrane protein CASK	0	0	2	2
Aurora kinase A	0	1	4	5
Cyclin-G-associated kinase	0	1	4	5
Serine/threonine-protein kinase DCLK1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	2	2
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	4	4
Peroxisomal acyl-coenzyme A oxidase 3	0	0	4	4
Mitogen-activated protein kinase 13	0	0	2	2
3-phosphoinositide-dependent protein kinase 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 13	0	0	2	2
Death-associated protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	4	4
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	4	4
NUAK family SNF1-like kinase 1	0	1	2	3
Dynamin-like 120 kDa protein, mitochondrial	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	2	2
Tyrosine-protein kinase JAK2	0	2	3	5
Rho-associated protein kinase 2	0	0	4	4
Serine/threonine-protein kinase ULK1	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	4	4
Ribosomal protein S6 kinase alpha-5	0	0	4	4
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	4	4
Ribosomal protein S6 kinase alpha-4	0	0	4	4
Serine/threonine-protein kinase 16	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	2	2
Serine/threonine-protein kinase PAK 3	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	2	2
Serine/threonine-protein kinase 17B	0	0	2	2
Serine/threonine-protein kinase 10	0	0	4	4
Serine/threonine-protein kinase D3	0	0	4	4
Cyclin-dependent kinase 14	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 6	0	0	4	4
Serine/threonine-protein kinase OSR1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	4	4
Serine/threonine-protein kinase LATS1	0	0	4	4
Serine/threonine-protein kinase PAK 4	0	2	4	6
Serine/threonine-protein kinase Chk2	0	1	2	3
Tyrosine-protein kinase ABL1	0	3	6	9
RAF proto-oncogene serine/threonine-protein kinase	0	2	3	6
High affinity nerve growth factor receptor	0	0	4	4
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	4	4
ADP/ATP translocase 2	0	0	4	4
Cytochrome P450 2E1	0	1	0	1
Protein kinase C beta type	0	0	4	4
Insulin receptor	0	2	4	6
Tyrosine-protein kinase Lck	0	2	4	6
Tyrosine-protein kinase Fyn	0	2	4	6
Glycogen phosphorylase, liver form	0	0	4	4
Tyrosine-protein kinase Fes/Fps	0	0	4	4
Macrophage colony-stimulating factor 1 receptor	0	2	2	4
Adenine phosphoribosyltransferase	0	0	4	4
Tyrosine-protein kinase Yes	0	1	4	5
Tyrosine-protein kinase Lyn	0	1	4	5
Proto-oncogene tyrosine-protein kinase receptor Ret	0	3	4	7
Insulin-like growth factor 1 receptor	0	0	4	4
Signal recognition particle receptor subunit alpha	0	0	3	3
Cytochrome c1, heme protein, mitochondrial	0	0	4	4
Hepatocyte growth factor receptor	0	1	4	5
Tyrosine-protein kinase HCK	0	3	4	7
Proto-oncogene tyrosine-protein kinase ROS	0	0	2	2
Platelet-derived growth factor receptor beta	0	4	4	8
Tyrosine-protein kinase Fgr	0	1	3	4
Quinolone resistance protein NorA	0	1	0	1
Wee1-like protein kinase 2	0	0	2	2
Uncharacterized serine/threonine-protein kinase SBK3	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	1	4	5
Cytochrome P450 2C8	0	3	0	4
Mast/stem cell growth factor receptor Kit	0	3	2	5
Glycogen phosphorylase, brain form	0	0	4	4
Breakpoint cluster region protein	0	0	5	5
Fibroblast growth factor receptor 1	0	2	4	6
Myosin light chain kinase, smooth muscle	0	0	2	2
Cyclin-dependent kinase 4	0	0	4	4
ADP/ATP translocase 3	0	0	4	4
Inosine-5'-monophosphate dehydrogenase 2	0	0	4	4
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	4	4
Insulin receptor-related protein	0	0	2	2
Serine/threonine-protein kinase B-raf	0	2	5	8
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	4	4
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	4	4
Platelet-derived growth factor receptor alpha	0	2	2	4
Tyrosine-protein kinase Fer	0	0	4	4
Protein kinase C alpha type	0	0	4	4
cAMP-dependent protein kinase catalytic subunit alpha	0	0	4	4
Vascular endothelial growth factor receptor 1	0	2	2	4
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	4	4
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Casein kinase II subunit alpha'	0	0	4	4
Ras-related protein Rab-6A	0	0	4	4
Serine/threonine-protein kinase MAK	0	0	2	2
Cyclin-dependent kinase 11B	0	0	2	2
Ephrin type-A receptor 1	0	0	4	4
Fibroblast growth factor receptor 2	0	0	2	2
Receptor tyrosine-protein kinase erbB-3	0	2	2	4
Multifunctional protein ADE2	0	0	4	4
Fibroblast growth factor receptor 4	0	0	2	2
Fibroblast growth factor receptor 3	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	3	3
cAMP-dependent protein kinase catalytic subunit beta	0	0	4	4
Ferrochelatase, mitochondrial	0	0	5	5
Ribosomal protein S6 kinase beta-1	0	0	4	4
Tyrosine-protein kinase JAK1	0	2	4	6
Sodium-dependent dopamine transporter	0	2	0	2
Protein kinase C eta type	0	0	2	2
Cyclin-dependent kinase 2	0	2	5	7
Beta-adrenergic receptor kinase 1	0	0	4	4
Cruzipain	0	1	0	1
Probable ATP-dependent RNA helicase DDX6	0	0	4	4
Activin receptor type-2A	0	0	2	2
Mitogen-activated protein kinase 3	0	0	4	4
MAP/microtubule affinity-regulating kinase 3	0	0	4	4
Ephrin type-A receptor 2	0	1	4	5
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Ephrin type-B receptor 2	0	0	4	4
Leukocyte tyrosine kinase receptor	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	4	4
UMP-CMP kinase	0	0	3	3
Phosphatidylethanolamine-binding protein 1	0	0	4	4
Wee1-like protein kinase	0	0	4	4
Heme oxygenase 2	0	0	4	4
Tyrosine-protein kinase receptor UFO	0	1	2	3
Mitogen-activated protein kinase 4	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	4	4
DnaJ homolog subfamily A member 1	0	0	4	4
RAC-alpha serine/threonine-protein kinase	0	1	4	5
RAC-beta serine/threonine-protein kinase	0	0	4	4
G protein-coupled receptor kinase 4	0	0	2	2
Dual specificity protein kinase TTK	0	0	3	3
DNA replication licensing factor MCM4	0	0	4	4
Type-1 angiotensin II receptor	0	2	0	2
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Vascular endothelial growth factor receptor 3	0	2	2	4
Vascular endothelial growth factor receptor 2	0	5	2	7
Dual specificity mitogen-activated protein kinase kinase 2	0	2	4	6
Receptor-type tyrosine-protein kinase FLT3	0	3	4	8
Bone morphogenetic protein receptor type-1A	0	0	4	4
Activin receptor type-1B	0	0	4	4
TGF-beta receptor type-1	0	0	4	4
Serine/threonine-protein kinase receptor R3	0	0	2	2
TGF-beta receptor type-2	0	0	4	4
Electron transfer flavoprotein subunit beta	0	0	3	3
Tyrosine-protein kinase CSK	0	1	4	5
Glycine--tRNA ligase	0	0	4	4
Mitogen-activated protein kinase kinase kinase 8	0	1	0	1
Protein kinase C iota type	0	0	4	4
Exosome RNA helicase MTR4	0	0	4	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	2	2	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	2	2	4
Serine/threonine-protein kinase mTOR	0	2	2	4
Megakaryocyte-associated tyrosine-protein kinase	0	0	2	2
Tyrosine-protein kinase Tec	0	1	4	5
Tyrosine-protein kinase TXK	0	1	3	4
Tyrosine-protein kinase ABL2	0	0	4	4
Tyrosine-protein kinase FRK	0	1	4	5
G protein-coupled receptor kinase 6	0	0	4	4
Tyrosine-protein kinase ZAP-70	0	0	2	2
Tyrosine-protein kinase SYK	0	1	4	5
26S proteasome regulatory subunit 6B	0	0	4	4
Mitogen-activated protein kinase 8	0	0	4	4
Mitogen-activated protein kinase 9	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 4	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 3	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	4	4
Casein kinase I isoform alpha	0	2	3	5
Casein kinase I isoform delta	0	0	4	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	2	4
MAP kinase-activated protein kinase 2	0	0	4	4
Cyclin-dependent kinase 8	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	4	4
Cysteine--tRNA ligase, cytoplasmic	0	0	3	3
Casein kinase I isoform epsilon	0	0	4	4
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	4	4
Dual specificity protein kinase CLK1	0	0	4	4
Dual specificity protein kinase CLK2	0	0	4	4
Dual specificity protein kinase CLK3	0	0	2	2
Glycogen synthase kinase-3 alpha	0	0	4	4
Glycogen synthase kinase-3 beta	0	0	4	4
Cyclin-dependent kinase 7	0	0	4	4
Cyclin-dependent kinase 9	0	0	4	4
Ras-related protein Rab-27A	0	0	4	4
Tyrosine-protein kinase Blk	0	1	3	4
Interleukin-1 receptor-associated kinase 1	0	0	4	4
Ribosomal protein S6 kinase alpha-3	0	1	4	5
Cytoplasmic tyrosine-protein kinase BMX	0	2	3	5
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	3	3
Serine/threonine-protein kinase Nek2	0	1	4	5
Serine/threonine-protein kinase Nek3	0	0	4	4
Serine/threonine-protein kinase Nek4	0	0	2	2
Tyrosine-protein kinase JAK3	0	2	3	5
Dual specificity mitogen-activated protein kinase kinase 6	0	0	4	4
Serine/threonine-protein kinase PLK1	0	2	4	6
Death-associated protein kinase 1	0	0	2	2
LIM domain kinase 1	0	0	4	4
LIM domain kinase 2	0	0	4	4
Mitogen-activated protein kinase 12	0	0	2	2
Mitogen-activated protein kinase 10	0	1	4	5
Tyrosine--tRNA ligase, cytoplasmic	0	0	4	4
5'-AMP-activated protein kinase subunit gamma-1	0	0	4	4
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	1	2	3
Ephrin type-B receptor 3	0	0	4	4
Ephrin type-A receptor 5	0	0	4	4
Ephrin type-B receptor 4	0	2	4	6
Ephrin type-B receptor 1	0	0	2	2
Ephrin type-A receptor 4	0	0	4	4
Adenylate kinase 2, mitochondrial	0	0	4	4
Adenosine kinase	0	0	4	4
Beta-secretase 1	0	1	0	1
Hormonally up-regulated neu tumor-associated kinase	0	0	2	2
Serine/threonine-protein kinase SIK1	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 4	0	0	2	2
Ras-related protein Rab-10	0	0	4	4
Cell division control protein 2 homolog	0	0	2	2
Actin-related protein 3	0	0	4	4
Actin-related protein 2	0	0	4	4
Calcium-dependent protein kinase 1	0	0	2	2
GTP-binding nuclear protein Ran	0	0	4	4
Tubulin alpha-1A chain	0	0	2	2
Casein kinase II subunit alpha	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
Casein kinase I isoform gamma-2	0	0	4	4
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Mitogen-activated protein kinase kinase kinase 9	0	0	2	2
Serine/threonine-protein kinase PknB	0	0	2	2
Cyclin-dependent kinase 3	0	0	4	4
Cyclin-dependent kinase-like 1	0	0	2	2
Cyclin-dependent kinase 6	0	0	4	4
Cyclin-dependent-like kinase 5	0	0	4	4
Cyclin-dependent kinase 16	0	0	4	4
Cyclin-dependent kinase 17	0	0	4	4
ATP-dependent 6-phosphofructokinase, platelet type	0	0	4	4
Synaptic vesicular amine transporter	0	2	0	2
Protein kinase C epsilon type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	1	4	5
Angiopoietin-1 receptor	0	1	2	3
Mitogen-activated protein kinase kinase kinase 10	0	0	2	2
Transcription factor p65	0	1	0	1
Protein kinase C theta type	0	0	4	4
Activin receptor type-1	0	0	4	4
Macrophage-stimulating protein receptor	0	0	4	4
Focal adhesion kinase 1	0	1	4	5
Protein kinase C zeta type	0	0	2	2
Protein kinase C delta type	0	0	4	4
Tyrosine-protein kinase BTK	0	2	5	7
Tyrosine-protein kinase receptor TYRO3	0	0	2	2
Cyclin-dependent kinase 18	0	0	2	2
Activated CDC42 kinase 1	0	0	4	4
Epithelial discoidin domain-containing receptor 1	0	0	4	4
Tyrosine-protein kinase ITK/TSK	0	1	3	4
Myotonin-protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 12	0	0	2	2
Tyrosine-protein kinase Mer	0	1	4	5
Serine/threonine-protein kinase 4	0	0	4	4
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	1	4	5
Serine/threonine-protein kinase PAK 1	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	4	4
Mitogen-activated protein kinase 7	0	0	4	4
Serine/threonine-protein kinase PAK 2	0	0	4	4
Serine/threonine-protein kinase 3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 1	0	0	4	4
cGMP-dependent protein kinase 2	0	0	2	2
Integrin-linked protein kinase	0	0	4	4
Rho-associated protein kinase 1	0	0	4	4
Non-receptor tyrosine-protein kinase TNK1	0	0	4	4
Serine/threonine-protein kinase PRP4 homolog	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	4	4
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	4	4
Activin receptor type-2B	0	0	4	4
Bone morphogenetic protein receptor type-2	0	0	4	4
Protein-tyrosine kinase 6	0	1	4	5
cGMP-dependent protein kinase 1	0	0	4	4
Cyclin-dependent kinase 13	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	4	4
Protein-tyrosine kinase 2-beta	0	0	4	4
Maternal embryonic leucine zipper kinase	0	0	4	4
Structural maintenance of chromosomes protein 1A	0	0	4	4
Chromodomain-helicase-DNA-binding protein 4	0	0	4	4
Peroxisomal acyl-coenzyme A oxidase 1	0	0	3	3
Serine/threonine-protein kinase D1	0	0	2	2
Serine/threonine-protein kinase 38	0	0	3	3
Receptor tyrosine-protein kinase erbB-4	0	2	3	5
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Ephrin type-A receptor 7	0	0	3	3
Delta(24)-sterol reductase	0	0	4	4
Ribosomal protein S6 kinase alpha-1	0	2	4	6
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	4	4
Mitogen-activated protein kinase 11	0	0	4	4
Serine/threonine-protein kinase STK11	0	0	4	4
Rhodopsin kinase GRK1	0	0	2	2
NT-3 growth factor receptor	0	0	2	2
Serine/threonine-protein kinase N1	0	0	4	4
Serine/threonine-protein kinase N2	0	0	4	4
Mitogen-activated protein kinase 14	0	1	4	5
Calcium/calmodulin-dependent protein kinase type IV	0	0	4	4
Mitogen-activated protein kinase kinase kinase 11	0	0	4	4
BDNF/NT-3 growth factors receptor	0	0	2	2
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
AP2-associated protein kinase 1	0	1	4	5
Myosin light chain kinase 3	0	0	4	4
Uncharacterized aarF domain-containing protein kinase 5	0	0	3	3
Serine/threonine-protein kinase ULK3	0	0	2	2
Serine/threonine-protein kinase SBK1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 19	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	4	4
Serine/threonine-protein kinase TNNI3K	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	4	4
Serine/threonine-protein kinase MRCK gamma	0	0	4	4
Acyl-CoA dehydrogenase family member 10	0	0	3	3
Serine/threonine-protein kinase Nek5	0	0	2	2
Serine/threonine-protein kinase N3	0	0	3	3
Serine/threonine-protein kinase ULK3	0	0	4	4
Dual serine/threonine and tyrosine protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 15	0	0	2	2
Uncharacterized protein FLJ45252	0	0	4	4
Acyl-CoA dehydrogenase family member 11	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	4	4
Serine/threonine-protein kinase MARK2	0	0	4	4
Serine/threonine-protein kinase TAO1	0	0	4	4
STE20-related kinase adapter protein alpha	0	0	4	4
Myosin-14	0	0	4	4
AarF domain-containing protein kinase 1	0	0	4	4
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	4	4
Serine/threonine-protein kinase VRK2	0	0	2	2
Myosin light chain kinase family member 4	0	0	2	2
Homeodomain-interacting protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	4	4
Cyclin-dependent kinase-like 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	0	4	4
Serine/threonine-protein kinase BRSK2	0	0	2	2
Serine/threonine-protein kinase NIM1	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	2	2
Serine/threonine-protein kinase ULK2	0	0	2	2
Misshapen-like kinase 1	0	0	3	3
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Homeodomain-interacting protein kinase 4	0	0	2	2
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Serine/threonine-protein kinase Nek11	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	4	4
Mitogen-activated protein kinase 15	0	0	4	4
Serine/threonine-protein kinase Nek9	0	0	4	4
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase 35	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	4	4
Rhodopsin kinase GRK7	0	0	2	2
Serine/threonine-protein kinase 32A	0	0	2	2
Myosin-IIIb	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	2	2
Cyclin-dependent kinase-like 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	4	4
Serine/threonine-protein kinase Sgk3	0	0	2	2
Atypical kinase COQ8B, mitochondrial	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1G	0	0	3	3
Serine/threonine-protein kinase Nek1	0	0	4	4
Cyclin-dependent kinase 15	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	4	4
EKC/KEOPS complex subunit TP53RK	0	0	4	4
SRSF protein kinase 1	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	4	4
Mitogen-activated protein kinase kinase kinase 5	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	4	4
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	4	4
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO2	0	0	2	2
Cyclin-dependent kinase 19	0	0	2	2
Transient receptor potential cation channel subfamily M member 6	0	0	2	2
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase 33	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	4	4
Serine/threonine-protein kinase D2	0	0	4	4
Serine/threonine-protein kinase DCLK3	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	4	4
RNA cytidine acetyltransferase	0	0	4	4
Serine/threonine-protein kinase SIK2	0	0	4	4
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	4	4
Serine/threonine-protein kinase TAO3	0	0	4	4
Homeodomain-interacting protein kinase 2	0	0	2	2
Tyrosine-protein kinase Srms	0	0	2	2
Homeodomain-interacting protein kinase 3	0	0	2	2
Serine/threonine-protein kinase PLK3	0	1	2	3
dCTP pyrophosphatase 1	0	0	4	4
Dual specificity protein kinase CLK4	0	0	4	4
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase Nek6	0	0	2	2
Casein kinase I isoform gamma-1	0	0	4	4
Serine/threonine-protein kinase PAK 6	0	1	3	4
SNF-related serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	4	4
Isoleucine--tRNA ligase, mitochondrial	0	0	2	2
BMP-2-inducible protein kinase	0	0	4	4
Obg-like ATPase 1	0	0	4	4
Midasin	0	0	4	4
Interleukin-1 receptor-associated kinase 4	0	0	4	4
Serine/threonine-protein kinase 32B	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	1	4	5
Cyclin-dependent kinase 12	0	0	4	4
Serine/threonine-protein kinase PLK2	0	1	2	3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	4	4
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	3	3
Serine/threonine-protein kinase PAK 5	0	1	2	3
Serine/threonine-protein kinase 26	0	0	4	4
eIF-2-alpha kinase GCN2	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	4	4
Serine/threonine-protein kinase NLK	0	0	4	4
Phosphatidylinositol 4-kinase beta	0	0	2	2
Serine/threonine-protein kinase 17A	0	0	2	2
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	4	4
Serine/threonine-protein kinase TBK1	0	1	4	5
Septin-9	0	0	4	4
Death-associated protein kinase 2	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	4	4
TRAF2 and NCK-interacting protein kinase	0	0	4	4
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	4	4
Long-chain-fatty-acid--CoA ligase 5	0	0	3	3
ALK tyrosine kinase receptor	0	1	2	3
SRSF protein kinase 3	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	4	4
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	4	4
Serine/threonine-protein kinase 38-like	0	0	3	3
Microtubule-associated serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 2	0	0	4	4
Thyroid hormone receptor-associated protein 3	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 3	0	0	4	4
Serine/threonine-protein kinase MRCK beta	0	0	4	4
Interleukin-1 receptor-associated kinase 3	0	0	4	4
Serine/threonine-protein kinase 24	0	0	3	3
Casein kinase I isoform gamma-3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 4	0	0	4	4
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Procathepsin L	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Equilibrative nucleoside transporter 1	0	1	0	1
Parkin	2	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
ATP-binding cassette sub-family C member 9	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	0	0	1
ATP synthase subunit beta, mitochondrial	0	1	0	1
ATP synthase subunit delta, mitochondrial	0	1	0	1
ATP synthase subunit gamma, mitochondrial	0	1	0	1
ATP synthase subunit epsilon, mitochondrial	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	1	1	2
5-hydroxytryptamine receptor 1A	0	7	1	8
Cholesteryl ester transfer protein	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	1	2	3
Guanine nucleotide-binding protein G	2	0	0	2
ATP-binding cassette sub-family C member 8	0	1	0	1
ATP-sensitive inward rectifier potassium channel 11	0	1	0	1
Solute carrier family 22 member 7	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	2	0	2
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	3	0	4
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
GALC protein	3	0	0	3
Chain A, Acetylcholinesterase	0	1	0	1
interferon gamma precursor	0	0	0	1
Solute carrier family 22 member 2	0	1	0	1
Interstitial collagenase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M4	0	4	0	4
Acetylcholinesterase	0	4	0	4
Multidrug and toxin extrusion protein 2	0	1	0	1
Estrogen receptor beta	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Epoxide hydrolase 1	0	0	0	1
Aldo-keto reductase family 1 member B1	0	5	0	5
Muscarinic acetylcholine receptor M2	0	4	0	4
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
5-hydroxytryptamine receptor 2A	0	5	0	5
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Translocator protein	0	2	0	2
Alpha-2B adrenergic receptor	0	7	0	7
Cytochrome P450 7A1	0	1	0	1
Estrogen receptor	0	1	0	1
Substance-K receptor	0	4	0	4
Sodium-dependent noradrenaline transporter	0	4	1	5
Thromboxane-A synthase	0	1	0	1
Histamine H2 receptor	0	4	0	4
Gonadotropin-releasing hormone receptor	0	3	1	4
Sodium-dependent serotonin transporter	0	4	1	5
Delta-type opioid receptor	0	4	0	4
Cytochrome P450 4F2	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Gonadotropin-releasing hormone receptor	0	1	0	1
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	1	2
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
streptokinase A precursor	0	0	1	1
Beta-lactamase	0	1	0	2
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase TEM	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	1	2
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	1	2
Beta-lactamase	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
Solute carrier family 22 member 3	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	1	0	0	1
dopamine D1 receptor	3	0	0	3
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	2	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
DNA polymerase beta	2	0	0	2
DNA polymerase eta isoform 1	2	0	0	2
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	4	0	5
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	3	0	4
Thymidylate synthase	0	3	0	3
Thymidylate synthase	0	4	0	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	4	0	5
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	3	2	5
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	2	0	2
Folate receptor alpha	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	3	0	3
Bifunctional purine biosynthesis protein ATIC	0	4	0	4
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	3	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	3	0	4
Multidrug resistance associated protein	0	1	0	2
Solute carrier family 22 member 11	0	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Glucocorticoid receptor	0	6	2	13
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
DNA polymerase III, partial	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
5-hydroxytryptamine receptor 4	0	4	0	4
D(2) dopamine receptor	0	5	0	5
D(1A) dopamine receptor	0	4	0	4
5-hydroxytryptamine receptor 2A	0	5	0	5
5-hydroxytryptamine receptor 2C	0	5	0	5
5-hydroxytryptamine receptor 1B	0	4	0	4
D(3) dopamine receptor	0	5	0	5
Beta-1 adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	2	1	3
Beta-3 adrenergic receptor	0	0	1	1
Beta-1 adrenergic receptor	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	0	1	1
5-hydroxytryptamine receptor 3E	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
5-hydroxytryptamine receptor 1A	0	3	2	5
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M1	0	2	0	2
D	0	2	0	2
D(3) dopamine receptor	0	1	0	1
Muscarinic acetylcholine receptor M3	0	2	0	2
Endothelin receptor type B	0	1	0	1
D(4) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 3A	0	2	0	2
Endothelin receptor type B	0	1	0	1
Endothelin-1 receptor	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1D	0	2	0	2
5-hydroxytryptamine receptor 1F	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 6	0	1	0	1
Histamine H1 receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	3	0	3
5-hydroxytryptamine receptor 7	0	2	0	2
5-hydroxytryptamine receptor 7	0	3	0	3
Alpha-1A adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Histamine H1 receptor	0	3	0	3
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 3A	0	2	0	2
D(2) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 4	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
5-hydroxytryptamine receptor 3B	0	2	0	2
G-protein coupled receptor	0	1	0	1
Transporter	0	5	0	5
Genome polyprotein	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
Integrin alpha-V	0	1	0	1
60 kDa chaperonin	0	1	0	1
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	1
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	2	0	2
Bcl-2-like protein 1	0	1	0	1
Thiosulfate sulfurtransferase	0	2	0	2
Beta-tubulin	0	1	0	1
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Putative nucleoside diphosphate kinase	0	0	1	1
Cytochrome P450 2B6	0	1	0	2
Nucleoside diphosphate kinase B	0	0	1	1
G1/S-specific cyclin-E1	0	1	0	1
Myosin-10	0	0	3	3
Choline-phosphate cytidylyltransferase A	0	0	2	2
MAP kinase-activated protein kinase 3	0	0	1	1
Rab-like protein 3	0	0	3	3
Sigma intracellular receptor 2	0	1	0	1
ATP-dependent RNA helicase DHX30	0	0	2	2
Nuclear receptor subfamily 4 group A member 3	0	1	0	1
Peroxiredoxin-like 2A	0	1	0	1
Platelet glycoprotein VI	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Serine hydroxymethyltransferase, cytosolic	0	1	1	2
Thymidylate synthase	0	1	0	1
Gamma-aminobutyric acid	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Chain A, AKAP9-BRAF fusion protein	0	1	0	1
Membrane-associated progesterone receptor component 1	0	0	2	2
Pirin	0	1	0	1
GTPase KRas	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Heat shock factor protein 1	0	1	0	1
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Serine/threonine-protein kinase ATR	0	0	2	2
Cyclin-dependent kinase 10	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	1	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Monocarboxylate transporter 4	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Chain A, Activated Factor Xa Heavy Chain	0	1	0	1
Coagulation factor X	0	2	0	2
Coagulation factor XII	0	1	0	1
Suppressor of tumorigenicity 14 protein	0	1	0	1
Genome polyprotein	0	1	0	1
Neuraminidase	0	2	0	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Polyphenol oxidase 2	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Albumin	0	1	0	1
Neuraminidase	0	1	0	1
Sialidase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Bifunctional epoxide hydrolase 2	0	2	0	2
Prolyl endopeptidase	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Substance-K receptor	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Platelet-derived growth factor receptor alpha	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Protein delta homolog 1	0	1	1	2
Mu-type opioid receptor	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	1	1
Bromodomain-containing protein 9	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Bromodomain-containing protein 7	0	0	1	1
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
serine/threonine-protein kinase PLK1	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
MSH	0	0	0	1
pyruvate kinase	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Albumin	0	0	1	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Superior Vena Cava Obstruction

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (180)

Protein Targets (1,426)

Superior Vena Cava Obstruction

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (180)

Drugs Studied (121)

Protein Targets (1,426)