n-ethylthiourea

Description

N-ethylthiourea : A member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by an ethyl group. [CHeBI]

Cross-References

ID Source	ID
PubMed CID	3032338
CHEMBL ID	116961
SCHEMBL ID	15539
SCHEMBL ID	14577426
CHEBI ID	188349
MeSH ID	M0186402

Synonyms (44)

Synonym
u54or2e97e ,
4-04-00-00374 (beilstein handbook reference)
unii-u54or2e97e
EN300-20484
NCIOPEN2_000299
1-ethyl-2-thiourea
n-ethylthiourea ,
n-ethylthiocarbamide
urea, 1-ethyl-2-thio-
nsc62921
nsc-62921
wln: suyzm2
ent 61326
625-53-6
thiourea, ethyl-
ethylthiourea
1-ethylthiourea
n-ethylthiourea, 99%
einecs 210-899-3
thiourea, n-ethyl-
ethyl-2-thiourea
ai3-61326
ethyl thiourea
brn 1699551
nsc 62921
hsdb 6776
CHEMBL116961
CHEBI:188349
AKOS000120054
FT-0626362
AKOS015898564
SCHEMBL15539
n-ethylthiourea [hsdb]
n-ethyl-thiourea
DTXSID0060804
SCHEMBL14577426
mfcd00004939
n-ethylthiourea, purum, >=98.0% (n)
BS-9984
CS-0180914
Q26840919
AMY18739
D86340
n-ethyl-2-thiourea

Drug Classes (1)

Class	Description
thioureas	Compounds of general formula RR'NC(=S)NR''R'''.

Protein Targets (1)

Activation Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)
Taste receptor type 2 member 38	Homo sapiens (human)	EC50	260.0000	AID1619468

Other Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)
Taste receptor type 2 member 38	Homo sapiens (human)	Activity	30.0000	AID1619467

Bioassays (1)

Assay ID	Title	Year	Journal	Article
AID23443	Partition coefficient (logP)	1985	Journal of medicinal chemistry, Mar, Volume: 28, Issue:3 ISSN: 0022-2623	Use of physicochemical parameters in distance geometry and related three-dimensional quantitative structure-activity relationships: a demonstration using Escherichia coli dihydrofolate reductase inhibitors.

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (20.00)	18.7374
1990's	1 (20.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (40.00)	24.3611
2020's	1 (20.00)	2.80

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%

Substance	Classes	Roles	Relationship Strength
tetramethylthiourea	thioureas		low
phenylthiourea	thioureas	EC 1.14.18.1 (tyrosinase) inhibitor	low
N-(4-fluorophenyl)-4-methyl-1-piperidinecarbothioamide	thioureas		low
1-(1,3-benzodioxol-5-ylmethyl)-3-(4-methylphenyl)thiourea	thioureas		low
diphenylthiourea	thioureas	allergen	low
1-(2-methoxyphenyl)-3-(2-pyridinyl)thiourea	thioureas		low
N-[(3-nitroanilino)-sulfanylidenemethyl]benzamide	thioureas		low
3-cyclohexyl-1,1-bis(2-methylpropyl)thiourea	thioureas		low
1-(2,5-dimethoxyphenyl)-3-phenylthiourea	thioureas		low
1-(3-fluorophenyl)-3-(2-pyridinylmethyl)thiourea	thioureas		low
1-(2-methoxyphenyl)-5-(phenylmethyl)-1,3,5-triazinane-2-thione	thioureas		low
3-(4-bromophenyl)-6-phenyl-1,4-dihydro-1,3,5-triazine-2-thione	thioureas		low
3-(4-methylphenyl)-6-phenyl-1,4-dihydro-1,3,5-triazine-2-thione	thioureas		low
1-(1,3-benzodioxol-5-ylmethyl)-3-(2-methylphenyl)thiourea	thioureas		low
N-(3-methoxyphenyl)-4-(phenylmethyl)-1-piperazinecarbothioamide	thioureas		low
1-(1,3-benzodioxol-5-ylmethyl)-3-(3-chloro-2-methylphenyl)thiourea	thioureas		low
1-(1,3-benzodioxol-5-ylmethyl)-3-(2,5-dimethylphenyl)thiourea	thioureas		low
3-(4-chlorophenyl)-6-phenyl-1,4-dihydro-1,3,5-triazine-2-thione	thioureas		low
1-(4-bromophenyl)-3-(2-phenylethyl)thiourea	thioureas		low
N-[(4-fluoroanilino)-sulfanylidenemethyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide	thioureas		low
1-(3-chlorophenyl)-3-(phenylmethyl)thiourea	thioureas		low
1-(4-chlorophenyl)-3-(2-furanylmethyl)thiourea	thioureas		low
1-(3,4-dichlorophenyl)-3-(3-pyridinylmethyl)thiourea	thioureas		low
1-(4-chlorophenyl)-3-(2-phenylethyl)thiourea	thioureas		low
N-[(3-acetylanilino)-sulfanylidenemethyl]-3-chlorobenzamide	thioureas		low
N-(2,4-dichlorophenyl)-1-piperidinecarbothioamide	thioureas		low
2-(4-chlorophenyl)-N-[(2-hydroxy-5-methylanilino)-sulfanylidenemethyl]acetamide	thioureas		low
1-[(2,4-dichlorophenyl)methyl]-3-phenylthiourea	thioureas		low
N-[[2-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]-2-thiophenecarboxamide	thioureas		low
N-(2,4-dimethylphenyl)-4-(phenylmethyl)-1-piperazinecarbothioamide	thioureas		low
N-[anilino(sulfanylidene)methyl]-5-bromo-2-furancarboxamide	thioureas		low
1-(phenylmethyl)-3-[4-(trifluoromethoxy)phenyl]thiourea	thioureas		low
1-(4-methyl-3-nitrophenyl)-3-[(4-methylphenyl)methyl]thiourea	thioureas		low
1-(2-chlorophenyl)-3-[(2-chlorophenyl)methyl]thiourea	thioureas		low
1-(3-chloro-4-methoxyphenyl)-3-[2-(4-methyl-1-piperidinyl)ethyl]thiourea	thioureas		low
2,2-dimethyl-N-[[2-(4-methyl-1-piperidinyl)anilino]-sulfanylidenemethyl]propanamide	thioureas		low
1-(4-bromophenyl)-3-(2-fluorophenyl)thiourea	thioureas		low
1-(3,4-dichlorophenyl)-3-(3,5-dimethylphenyl)thiourea	thioureas		low
tenovin-1	thioureas		low
N-[[3-(hydroxymethyl)anilino]-sulfanylidenemethyl]-4-phenylbenzamide	thioureas		low
5-bromo-N-[[4-[(3,5-dimethylphenyl)sulfamoyl]anilino]-sulfanylidenemethyl]-2-furancarboxamide	thioureas		low
N-[(3-acetylanilino)-sulfanylidenemethyl]-5-bromo-3-pyridinecarboxamide	thioureas		low
4-[[[[oxo-(4-phenylphenyl)methyl]amino]-sulfanylidenemethyl]amino]benzoic acid	thioureas		low
3,4-dimethoxy-N-[[4-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]benzamide	thioureas		low
N-[[3-chloro-4-(4-morpholinyl)anilino]-sulfanylidenemethyl]-2-thiophenecarboxamide	thioureas		low
N-[[3-chloro-4-(4-morpholinyl)anilino]-sulfanylidenemethyl]-2-(4-methoxyphenoxy)acetamide	thioureas		low
N-[[3-chloro-4-(1-piperidinyl)anilino]-sulfanylidenemethyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide	thioureas		low
N-[(4-ethylanilino)-sulfanylidenemethyl]-3-methylbutanamide	thioureas		low
N-[(2-fluoroanilino)-sulfanylidenemethyl]-2-(4-methoxyphenoxy)acetamide	thioureas		low
N-[[3-chloro-2-(4-morpholinyl)anilino]-sulfanylidenemethyl]-4-methoxy-3-nitrobenzamide	thioureas		low
N-[[3-chloro-2-(1-piperidinyl)anilino]-sulfanylidenemethyl]-2-thiophenecarboxamide	thioureas		low
1-[[4-(dimethylamino)phenyl]methyl]-1-(2-furanylmethyl)-3-(4-methoxyphenyl)thiourea	thioureas		low
N-[[2-methyl-5-(2-oxazolo[4,5-b]pyridinyl)anilino]-sulfanylidenemethyl]-2-furancarboxamide	thioureas		low
2,4-dimethyl-N-[[4-(4-morpholinyl)anilino]-sulfanylidenemethyl]benzamide	thioureas		low
2-(4-chlorophenyl)-N-[[2-(4-morpholinyl)anilino]-sulfanylidenemethyl]acetamide	thioureas		low
N-[[2-(4-morpholinyl)anilino]-sulfanylidenemethyl]-4-nitrobenzamide	thioureas		low
N-[(3,5-dimethoxyanilino)-sulfanylidenemethyl]-3-phenylpropanamide	thioureas		low
3-methoxy-N-[[2-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]benzamide	thioureas		low
2-methoxy-N-[[2-(1-piperidinyl)anilino]-sulfanylidenemethyl]benzamide	thioureas		low
1-(4-bromophenyl)-3-(3-methylbutyl)thiourea	thioureas		low
5-bromo-N-[(2-carbamoylanilino)-sulfanylidenemethyl]-2-furancarboxamide	thioureas		low
2-chloro-5-[[[[(3,5-dimethoxyphenyl)-oxomethyl]amino]-sulfanylidenemethyl]amino]benzoic acid	thioureas		low
3-[[[[[5-(4-chlorophenyl)-2-furanyl]-oxomethyl]amino]-sulfanylidenemethyl]amino]-4-methoxybenzoic acid	thioureas		low
2-(4-bromophenoxy)-N-[(2-hydroxy-5-methylanilino)-sulfanylidenemethyl]acetamide	thioureas		low
N-[[5-(5,7-dimethyl-1,3-benzoxazol-2-yl)-2-methylanilino]-sulfanylidenemethyl]-2-thiophenecarboxamide	thioureas		low
N-[[3-(2-oxazolo[4,5-b]pyridinyl)anilino]-sulfanylidenemethyl]-2-furancarboxamide	thioureas		low
5-(3-nitrophenyl)-N-[[2-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]-2-furancarboxamide	thioureas		low
1-[2-(5,6-dimethyl-1H-benzimidazol-2-yl)ethyl]-3-(2,5-dimethylphenyl)-1-(3-pyridinylmethyl)thiourea	thioureas		low
1-[2-(5,6-dimethyl-1H-benzimidazol-2-yl)ethyl]-3-(2-methoxyphenyl)-1-(3-pyridinylmethyl)thiourea	thioureas		low
allylthiourea	thioureas	metabolite	low
N-[[4-[(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamoyl]anilino]-sulfanylidenemethyl]benzamide	thioureas		low
3-propoxy-N-[sulfanylidene-[3-(trifluoromethyl)anilino]methyl]benzamide	thioureas		low
N-[[3-chloro-4-(1-piperidinyl)anilino]-sulfanylidenemethyl]hexanamide	thioureas		low
4-phenyl-N-[sulfanylidene-(2,4,6-trimethylanilino)methyl]benzamide	thioureas		low
1-[2-(2-methylphenoxy)ethyl]-3-phenylthiourea	thioureas		low
1-[2-[(3-chloro-4-methoxyphenyl)methylthio]ethyl]-3-phenylthiourea	thioureas		low
3,4,5-trimethoxy-N-[[2-(4-morpholinyl)anilino]-sulfanylidenemethyl]benzamide	thioureas		low
1-(3,5-dimethoxyphenyl)-3-(3-pyridinyl)thiourea	thioureas		low
1-[2-[(4-chlorophenyl)thio]ethyl]-3-(2-methoxyphenyl)thiourea	thioureas		low
1-(2-methoxyphenyl)-3-[2-[(4-methylphenyl)thio]ethyl]thiourea	thioureas		low
1-(3-chlorophenyl)-3-(thiophen-2-ylmethyl)thiourea	thioureas		low
1-(4-ethylphenyl)-3-(phenylmethyl)thiourea	thioureas		low
1-[2-(5-fluoro-2-methyl-1H-indol-3-yl)ethyl]-3-(3-fluorophenyl)-1-(3-pyridinylmethyl)thiourea	thioureas		low
1-[2-(5-fluoro-2-methyl-1H-indol-3-yl)ethyl]-3-(4-fluorophenyl)-1-(3-pyridinylmethyl)thiourea	thioureas		low
1-[2-(5-fluoro-2-methyl-1H-indol-3-yl)ethyl]-3-(4-fluorophenyl)-1-(pyridin-4-ylmethyl)thiourea	thioureas		low
1-[2-[(4-chlorophenyl)thio]ethyl]-3-(2,4-dimethylphenyl)thiourea	thioureas		low
1-(3,5-dimethylphenyl)-3-(3-ethoxypropyl)thiourea	thioureas		low
1-(2,4-dimethylphenyl)-3-[2-[(4-methylphenyl)thio]ethyl]thiourea	thioureas		low
1-[2-[(2-methylphenyl)methylthio]ethyl]-3-phenylthiourea	thioureas		low
4-[[(5-chloro-2-methoxyanilino)-sulfanylidenemethyl]amino]-1-ethyl-3-pyrazolecarboxamide	thioureas		low
1-(5-chloro-2-methoxyphenyl)-3-[3-(2-oxo-1-pyrrolidinyl)propyl]thiourea	thioureas		low
1-(4-bromo-2-chlorophenyl)-3-(3-methyl-2-pyridinyl)thiourea	thioureas		low
3-[[(2,4-dichloroanilino)-sulfanylidenemethyl]amino]-4-methylbenzoic acid	thioureas		low
N-[[4-(dimethylsulfamoyl)anilino]-sulfanylidenemethyl]-2-phenylacetamide	thioureas		low
N-[(3-bromoanilino)-sulfanylidenemethyl]-3-phenylpropanamide	thioureas		low
N-[[3-chloro-2-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]butanamide	thioureas		low
3,4-dimethyl-N-[sulfanylidene-[2-(trifluoromethyl)anilino]methyl]benzamide	thioureas		low
1-[4-(difluoromethylthio)phenyl]-3-(phenylmethyl)thiourea	thioureas		low
1-(2-tert-butylphenyl)-3-cyclohexylthiourea	thioureas		low
1-(2,6-dimethylphenyl)-3-[3-(2-oxo-1-pyrrolidinyl)propyl]thiourea	thioureas		low
1-(2,6-diethylphenyl)-3-(1H-indazol-6-yl)thiourea	thioureas		low
1-[[4-[[[(4-chloro-3-fluoroanilino)-sulfanylidenemethyl]amino]methyl]phenyl]methyl]-3-(4-chloro-3-fluorophenyl)thiourea	thioureas		low
1-(2,6-diethylphenyl)-3-[2-(3,4-dihydroxyphenyl)ethyl]thiourea	thioureas		low
1-(2-chlorophenyl)-3-(3-phenylpropyl)thiourea	thioureas		low
4-benzoyl-N-(4-methoxyphenyl)-1-piperazinecarbothioamide	thioureas		low
1-(2-chlorophenyl)-3-(2-oxo-1,3-dihydrobenzimidazol-5-yl)thiourea	thioureas		low
acetylthiourea	acetamides; thioureas		low
1,3-dibutyl-2-thiourea	thioureas	allergen	low
n-methylthiourea	thioureas	drug metabolite; hepatotoxic agent; human xenobiotic metabolite	low
thiosemicarbazide	hydrazines; thiocarboxamide; thioureas		low
thiourea	one-carbon compound; thioureas; ureas	antioxidant; chromophore	low
1-(4-tert-butylphenyl)-3-(3-pyridinylmethyl)thiourea	thioureas		low
1-(4-methoxyphenyl)-3-(6-methyl-2-pyridinyl)thiourea	thioureas		low
1-(3-methylphenyl)-3-(2-pyridinyl)thiourea	thioureas		low
capsazepine	benzazepine; catechols; monochlorobenzenes; thioureas	capsaicin receptor antagonist	low
(2-bromophenyl)thiourea	thioureas		low
N-[2-(trifluoromethyl)phenyl]pyrrolidine-1-carbothioamide	thioureas		low
1-(4-hydroxyphenyl)-3-(3-methoxyphenyl)thiourea	thioureas		low
5-[[(4-methoxyanilino)-sulfanylidenemethyl]amino]-1H-pyrazole-4-carboxylic acid ethyl ester	thioureas		low
2-[[sulfanylidene-[[2,2,2-trichloro-1-[[(2-nitrophenyl)-oxomethyl]amino]ethyl]amino]methyl]amino]benzoic acid	thioureas		low
3-[[sulfanylidene-[[2,2,2-trichloro-1-[[(3-nitrophenyl)-oxomethyl]amino]ethyl]amino]methyl]amino]benzoic acid	thioureas		low
2-[[sulfanylidene-[[2,2,2-trichloro-1-[(1-oxo-2-phenoxyethyl)amino]ethyl]amino]methyl]amino]benzoic acid	thioureas		low
N-[(2-chloroanilino)-sulfanylidenemethyl]-2-furancarboxamide	thioureas		low
1-[1-(2,3-dihydro-1,4-benzodioxin-3-yl)ethyl]-3-phenylthiourea	thioureas		low
N-[2,2,2-trichloro-1-[[sulfanylidene-(2,4,6-trimethylanilino)methyl]amino]ethyl]benzamide	thioureas		low
N-[1-[[anilino(sulfanylidene)methyl]amino]-2,2,2-trichloroethyl]-2-(4-ethylphenoxy)acetamide	thioureas		low
2-chloro-N-[(2-hydroxy-5-methylanilino)-sulfanylidenemethyl]benzamide	thioureas		low
1-[2-(4-chlorophenyl)ethyl]-3-(4-fluorophenyl)thiourea	thioureas		low
N-(4-anilinophenyl)-3-(hydroxymethyl)-1-piperidinecarbothioamide	thioureas		low
N-(4-chloro-2,5-dimethoxyphenyl)-3-methyl-1-piperidinecarbothioamide	thioureas		low
3-nitro-N-[[4-[4-(1-oxopropyl)-1-piperazinyl]anilino]-sulfanylidenemethyl]benzamide	thioureas		low
N-[(4-sulfamoylanilino)-sulfanylidenemethyl]-1,3-benzodioxole-5-carboxamide	thioureas		low
monastrol	enoate ester; ethyl ester; phenols; racemate; thioureas	antileishmanial agent; antimitotic; antineoplastic agent; EC 3.5.1.5 (urease) inhibitor	low
2,2-dimethyl-N-[[4-(pyridin-4-ylmethyl)anilino]-sulfanylidenemethyl]propanamide	thioureas		low
sulfathiourea	substituted aniline; sulfonamide antibiotic; thioureas	antibacterial drug; EC 2.5.1.15 (dihydropteroate synthase) inhibitor	low
thiocarlide	thioureas		low
thiophanate	benzimidazole precursor fungicide; carbamate ester; carbamate fungicide; thioureas	antifungal agrochemical	low
thiophanate	benzimidazole precursor fungicide; carbamate ester; carbamate fungicide; thioureas	antifungal drug	low
N-[2,2,2-trichloro-1-[[(2,6-dichloroanilino)-sulfanylidenemethyl]amino]ethyl]carbamic acid (phenylmethyl) ester	thioureas		low
3,4-dimethoxy-N-[(2-methyl-4-nitroanilino)-sulfanylidenemethyl]benzamide	thioureas		low
1-(3-chlorophenyl)-3-(9-cyclopentyl-9-azabicyclo[3.3.1]nonan-3-yl)thiourea	thioureas		low
1-(9-cyclopentyl-9-azabicyclo[3.3.1]nonan-3-yl)-3-(3,5-dimethylphenyl)thiourea	thioureas		low
N-(2,4-dimethoxyphenyl)-3-(6-methyl-1H-benzimidazol-2-yl)-1-piperidinecarbothioamide	thioureas		low
N-[[3-[(3-chlorophenyl)sulfamoyl]-4-methylanilino]-sulfanylidenemethyl]-4-fluorobenzamide	thioureas		low
4-[[(3,4-dimethoxyphenyl)methyl-[(4-methylanilino)-sulfanylidenemethyl]amino]methyl]benzoic acid	thioureas		low
1-(6-methyl-2-pyridinyl)-3-[3-(trifluoromethyl)phenyl]thiourea	thioureas		low
N-[4-(difluoromethoxy)phenyl]-4-(phenylmethyl)-1-piperazinecarbothioamide	thioureas		low
1-(2-furanylmethyl)-3-(2-methylphenyl)-1-(3-pyridinylmethyl)thiourea	thioureas		low
1-[2-(dimethylamino)ethyl]-3-(2,4-dimethylphenyl)-1-(thiophen-2-ylmethyl)thiourea	thioureas		low
5-[[(3,4-dichloroanilino)-sulfanylidenemethyl]amino]-1H-pyrazole-4-carboxylic acid methyl ester	thioureas		low
3-(3-chloro-2-methylphenyl)-1-[(4-methylphenyl)methyl]-1-(3-pyridinylmethyl)thiourea	thioureas		low
2-(2,4-dibromophenoxy)-N-[[3-(hydroxymethyl)anilino]-sulfanylidenemethyl]acetamide	thioureas		low
1-[2-[(4-chlorophenyl)thio]ethyl]-3-(4-methylphenyl)thiourea	thioureas		low
1-(2-ethyl-6-methylphenyl)-3-[(1-methyl-2-pyrrolyl)methyl]thiourea	thioureas		low
1-(1-adamantyl)-3-(3,4-dimethoxyphenyl)thiourea	thioureas		low
N-[(3-hydroxyanilino)-sulfanylidenemethyl]-2-furancarboxamide	thioureas		low
4-chloro-N-[(4-ethoxy-2-nitroanilino)-sulfanylidenemethyl]-2,5-dimethyl-3-pyrazolecarboxamide	thioureas		low
3-nitro-N-[(3-sulfamoylanilino)-sulfanylidenemethyl]benzamide	thioureas		low
1-(3,3-dimethylbutan-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea	thioureas		low
5-[[(2-methylanilino)-sulfanylidenemethyl]amino]-1H-pyrazole-4-carboxylic acid methyl ester	thioureas		low
3-(3-chloro-4-methoxyphenyl)-1-(2-methoxyethyl)-1-(1-propan-2-yl-4-piperidinyl)thiourea	thioureas		low
2-[4-[[[[(2,4-dichlorophenyl)-oxomethyl]amino]-sulfanylidenemethyl]amino]-3-methylphenyl]-3,3,3-trifluoro-2-hydroxypropanoic acid ethyl ester	thioureas		low
1-(3-chlorophenyl)-3-[2-(dimethylamino)-2-phenylethyl]thiourea	thioureas		low
1-(4-methoxyphenyl)-3-(1-thiophen-2-ylpropan-2-yl)thiourea	thioureas		low
1-[4-[[4-[[(2-methoxyanilino)-sulfanylidenemethyl]amino]cyclohexyl]methyl]cyclohexyl]-3-(2-methoxyphenyl)thiourea	thioureas		low
1-[3-(dimethylamino)propyl]-1-(phenylmethyl)-3-[3-(trifluoromethyl)phenyl]thiourea	thioureas		low
4-bromo-N-[(4-ethoxy-2-nitroanilino)-sulfanylidenemethyl]-2-methyl-3-pyrazolecarboxamide	thioureas		low
1-(5-chloro-2,4-dimethoxyphenyl)-3-(phenylmethyl)thiourea	thioureas		low
1-(2-furanylmethyl)-3-(3-methoxyphenyl)-1-[2-(2-methyl-1H-indol-3-yl)ethyl]thiourea	thioureas		low
1-[2-[(4-pentoxyphenyl)methylthio]ethyl]-3-phenylthiourea	thioureas		low
noxythiolin	thioureas		low
amocarzine	C-nitro compound; N-methylpiperazine; secondary amino compound; thioureas	antinematodal drug	low
salubrinal	aminal; organochlorine compound; quinolines; secondary carboxamide; thioureas		low
ki11502	aromatic ether; benzamides; quinolines; thioureas	antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor	low
3-(3-chlorophenyl)-1-[(1-methyl-3-indolyl)methyl]-1-[3-(4-morpholinyl)propyl]thiourea	thioureas		low
1-(3-chlorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)thiourea	thioureas		low
tenovin-6	monocarboxylic acid amide; tertiary amino compound; thioureas	antineoplastic agent; p53 activator; Sir2 inhibitor	low
N-[[3-fluoro-4-[[2-(1-methyl-4-imidazolyl)-7-thieno[3,2-b]pyridinyl]oxy]anilino]-sulfanylidenemethyl]-2-phenylacetamide	thioureas		low

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	pre-1990
monoisopropanolamine	1	amino alcohol; secondary alcohol	Escherichia coli metabolite	1985	1985	39.0	low	1
acetic acid	1	monocarboxylic acid	antimicrobial food preservative; Daphnia magna metabolite; food acidity regulator; protic solvent	1985	1985	39.0	low	1
acetone	1	ketone body; methyl ketone; propanones; volatile organic compound	EC 3.5.1.4 (amidase) inhibitor; human metabolite; polar aprotic solvent	1985	1985	39.0	low	1
formic acid	1	monocarboxylic acid	antibacterial agent; astringent; metabolite; protic solvent; solvent	1985	1985	39.0	low	1
methane	1	alkane; gas molecular entity; mononuclear parent hydride; one-carbon compound	bacterial metabolite; fossil fuel; greenhouse gas	1985	1985	39.0	low	1
3-cresol	1	cresol	human xenobiotic metabolite	1985	1985	39.0	low	1
methanol	1	alkyl alcohol; one-carbon compound; primary alcohol; volatile organic compound	amphiprotic solvent; Escherichia coli metabolite; fuel; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite	1985	1985	39.0	low	1
pyridine	1	azaarene; mancude organic heteromonocyclic parent; monocyclic heteroarene; pyridines	environmental contaminant; NMR chemical shift reference compound	1985	1985	39.0	low	1
2-mercaptoacetate	1	sulfur-containing carboxylic acid		1985	1985	39.0	high	1
urea	1	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	1985	1985	39.0	low	1
ether	1	ether; volatile organic compound	inhalation anaesthetic; non-polar solvent; refrigerant	1985	1985	39.0	low	1
halothane	1	haloalkane; organobromine compound; organochlorine compound; organofluorine compound	inhalation anaesthetic	1985	1985	39.0	low	1
trimethoprim	1	aminopyrimidine; methoxybenzenes	antibacterial drug; diuretic; drug allergen; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; environmental contaminant; xenobiotic	1985	1985	39.0	low	1
aniline	1	anilines; primary arylamine		1985	1985	39.0	low	1
dimethylnitrosamine	1	nitrosamine	geroprotector; mutagen	1985	1985	39.0	low	1
chloroform	1	chloromethanes; one-carbon compound	carcinogenic agent; central nervous system drug; inhalation anaesthetic; non-polar solvent; refrigerant	1985	1985	39.0	low	1
bromoacetate	1			1985	1985	39.0	high	1
1,1,1-trichloroethane	1	chloroethanes	polar solvent	1985	1985	39.0	low	1
methyl bromide	1	bromohydrocarbon; bromomethanes; methyl halides	algal metabolite; fumigant insecticide; marine metabolite	1985	1985	39.0	low	1
ethylene	1	alkene; gas molecular entity	plant hormone; refrigerant	1985	1985	39.0	low	1
acetylene	1	alkyne; gas molecular entity; terminal acetylenic compound		1985	1985	39.0	low	1
methyl chloride	1	chloromethanes; methyl halides	marine metabolite; mutagen; refrigerant	1985	1985	39.0	low	1
methyl iodide	1	iodomethanes; methyl halides	fumigant insecticide	1985	1985	39.0	low	1
methylamine	1	methylamines; one-carbon compound; primary aliphatic amine	mouse metabolite	1985	1985	39.0	low	1
methylacetylene	1	alkyne; gas molecular entity; terminal acetylenic compound		1985	1985	39.0	low	1
ethyl chloride	1	chloroethanes	antipruritic drug; inhalation anaesthetic; local anaesthetic	1985	1985	39.0	low	1
ethylamine	1	primary aliphatic amine	human metabolite	1985	1985	39.0	low	1
acetonitrile	1	aliphatic nitrile; volatile organic compound	EC 3.5.1.4 (amidase) inhibitor; NMR chemical shift reference compound; polar aprotic solvent	1985	1985	39.0	low	1
methylene chloride	1	chloromethanes; volatile organic compound	carcinogenic agent; polar aprotic solvent; refrigerant	1985	1985	39.0	low	1
difluoromethane	1	fluoromethanes	refrigerant	1985	1985	39.0	low	1
2-propylamine	1	alkylamines; primary aliphatic amine		1985	1985	39.0	low	1
1,1-dichloroethane	1	organochlorine compound		1985	1985	39.0	low	1
1,1-difluoroethane	1			1985	1985	39.0	low	1
1,1-difluoroethylene	1	olefinic compound; organofluorine compound		1985	1985	39.0	low	1
dichlorofluoromethane	1			1985	1985	39.0	high	1
fluorocarbon 22	1	hydrochlorofluorocarbon		1985	1985	39.0	low	1
nitromethane	1	primary nitroalkane; volatile organic compound	EC 4.3.1.3 (histidine ammonia-lyase) inhibitor; explosive; NMR chemical shift reference compound; polar aprotic solvent	1985	1985	39.0	low	1
trifluoroethanol	1	fluoroalcohol		1985	1985	39.0	low	1
freon 114	1			1985	1985	39.0	low	1
perfluoroethane	1	fluoroalkane; fluorocarbon	refrigerant	1985	1985	39.0	low	1
methylethyl ketone	1	butanone; dialkyl ketone; methyl ketone; volatile organic compound	bacterial metabolite; polar aprotic solvent	1985	1985	39.0	low	1
trichloroethylene	1	chloroethenes	inhalation anaesthetic; mouse metabolite	1985	1985	39.0	low	1
n-methylacetamide	1	acetamides; monocarboxylic acid amide	metabolite	1985	1985	39.0	low	1
methyl acetate	1	acetate ester; methyl ester; volatile organic compound	EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor; fragrance; polar aprotic solvent	1985	1985	39.0	low	1
nitroethane	1	primary nitroalkane		1985	1985	39.0	low	1
benzenesulfonamide	1	sulfonamide		1985	1985	39.0	low	1
nitrobenzene	1	nitroarene; nitrobenzenes		1985	1985	39.0	low	1
3-nitrotoluene	1	mononitrotoluene		1985	1985	39.0	low	1
3-dinitrobenzene	1	dinitrobenzene	neurotoxin	1985	1985	39.0	low	1
anisole	1	monomethoxybenzene	plant metabolite	1985	1985	39.0	low	1
methylphenylsulfide	1	aryl sulfide; benzenes		1985	1985	39.0	low	1
1-butene	1	butene		1985	1985	39.0	low	1
propylamine	1	alkylamines		1985	1985	39.0	high	1
acrylonitrile	1	aliphatic nitrile; volatile organic compound	antifungal agent; carcinogenic agent; fungal metabolite; mutagen; polar aprotic solvent	1985	1985	39.0	low	1
3-chloroaniline	1			1985	1985	39.0	low	1
bromobenzene	1	bromoarene; bromobenzenes; volatile organic compound	hepatotoxic agent; mouse metabolite; non-polar solvent	1985	1985	39.0	low	1
chlorobenzene	1	monochlorobenzenes	solvent	1985	1985	39.0	low	1
thiophenol	1	aryl thiol		1985	1985	39.0	low	1
ethyl vinyl ether	1			1985	1985	39.0	low	1
pyrroles	1	pyrrole; secondary amine		1985	1985	39.0	low	1
2-ethoxyethanol	1	glycol ether; primary alcohol	protic solvent; teratogenic agent	1985	1985	39.0	low	1
propylene	1	alkene; gas molecular entity	refrigerant; xenobiotic	1985	1985	39.0	low	1
dimethyl ether	1	ether		1985	1985	39.0	low	1
2,2,2-trichloroethanol	1	chloroethanol	mouse metabolite	1985	1985	39.0	low	1
ethyl acetate	1	acetate ester; ethyl ester; volatile organic compound	EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor; metabolite; polar aprotic solvent; Saccharomyces cerevisiae metabolite	1985	1985	39.0	low	1
cycloguanil	1	triazines	antifolate; antiinfective agent; antimalarial; antiparasitic agent; antiprotozoal drug; EC 1.5.1.3 (dihydrofolate reductase) inhibitor	1985	1985	39.0	low	1
diethyl sulfide	1	ethyl sulfide		1985	1985	39.0	low	1
2-fluoroethanol	1			1985	1985	39.0	low	1
fluorobenzenes	1	monofluorobenzenes	NMR chemical shift reference compound	1985	1985	39.0	low	1
propadiene	1	allenes		1985	1985	39.0	low	1
dimethylacetylene	1			1985	1985	39.0	medium	1
nitrosobenzene	1	benzenes; nitroso compound	xenobiotic metabolite	1985	1985	39.0	low	1
iodobenzene	1			1985	1985	39.0	low	1
fluoromethane	1	fluorohydrocarbon; fluoromethanes; methyl halides	refrigerant	1985	1985	39.0	low	1
diisopropylnitrosamine	1			1985	1985	39.0	medium	1
methylnitrosourea	1	N-nitrosoureas	alkylating agent; carcinogenic agent; mutagen; teratogenic agent	1985	1985	39.0	low	1
methyl phenyl sulfoxide	1	benzenes; sulfoxide		1985	1985	39.0	low	1
2,5-dihydrofuran	1			1985	1985	39.0	medium	1
4,6-diamino-2,2-dimethyl-1,2-dihydro-1-phenyl-s-triazine	1			1985	1985	39.0	low	1
diaveridine	1	aminopyrimidine	antiparasitic agent; drug allergen	1985	1985	39.0	low	1
tetrachloroethylene	1	chlorocarbon; chloroethenes	nephrotoxic agent	1985	1985	39.0	low	1
trichloroacetamide	1			1985	1985	39.0	low	1
trifluoroacetamide	1			1985	1985	39.0	low	1
5-iodouracil	1	organoiodine compound	antimetabolite	1985	1985	39.0	low	1
2,4-diamino-5-benzylpyrimidine	1			1985	1985	39.0	low	1
carbodiimides	1	carbodiimide		1985	1985	39.0	low	1
thiourea	1	one-carbon compound; thioureas; ureas	antioxidant; chromophore	1985	1985	39.0	low	1
5-nitroso-salicylate	1	hydroxybenzoic acid		1985	1985	39.0	high	1

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	1990's	2000's	2010's	post-2020
dimethyl sulfoxide	1	sulfoxide; volatile organic compound	alkylating agent; antidote; Escherichia coli metabolite; geroprotector; MRI contrast agent; non-narcotic analgesic; polar aprotic solvent; radical scavenger	2022	2022	2.0	low	0	0	0	1
silver	1	copper group element atom; elemental silver	Escherichia coli metabolite	2010	2010	14.0	low	0	1	0	0
daunorubicin	1	aminoglycoside antibiotic; anthracycline; p-quinones; tetracenequinones	antineoplastic agent; bacterial metabolite	1991	1991	33.0	low	1	0	0	0
phenylthiourea	1	thioureas	EC 1.14.18.1 (tyrosinase) inhibitor	1991	1991	33.0	low	1	0	0	0
thiourea	4	one-carbon compound; thioureas; ureas	antioxidant; chromophore	1991	2022	14.0	low	1	1	1	1

Condition	Indicated	Studies	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
Glial Cell Tumors	0	1	2017	2017	7.0	high	0	0	0	0	1	0
Glioma	0	1	2017	2017	7.0	high	0	0	0	0	1	0

n-ethylthiourea

Description

Cross-References

Synonyms (44)

Drug Classes (1)

Protein Targets (1)

Activation Measurements

Other Measurements

Bioassays (1)

Research

Studies (5)

Study Types

Related Drugs (267)

Drugs in this Class (177)

Drugs Involved in Assays Together (88)

Drugs Researched Together (5)

Related Conditions (2)