| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Carcinogenesis
The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. | 0 | 3.09 | 1 | 0 |
Benign Neoplasms, Brain
[description not available] | 0 | 7.27 | 6 | 3 |
Glial Cell Tumors
[description not available] | 0 | 7.41 | 7 | 3 |
Experimental Neoplasms
[description not available] | 0 | 2.21 | 1 | 0 |
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 7.27 | 6 | 3 |
Glioma
Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21) | 1 | 9.41 | 7 | 3 |
Congenital Zika Syndrome
[description not available] | 0 | 2.25 | 1 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 2.69 | 2 | 0 |
Zika Virus Infection
A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME. | 0 | 2.25 | 1 | 0 |
Cholangiocellular Carcinoma
[description not available] | 0 | 11.16 | 17 | 4 |
Bile Duct Cancer
[description not available] | 0 | 11.16 | 17 | 4 |
Bile Duct Neoplasms
Tumors or cancer of the BILE DUCTS. | 0 | 11.16 | 17 | 4 |
Cholangiocarcinoma
A malignant tumor arising from the epithelium of the BILE DUCTS. | 1 | 13.16 | 17 | 4 |
Acute Myelogenous Leukemia
[description not available] | 0 | 15.31 | 58 | 14 |
Local Neoplasm Recurrence
[description not available] | 0 | 4.66 | 4 | 1 |
Leukemia, Myeloid, Acute
Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES. | 1 | 17.31 | 58 | 14 |
Benign Neoplasms
[description not available] | 0 | 6.23 | 3 | 1 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 1 | 10.29 | 6 | 2 |
Disease Exacerbation
[description not available] | 0 | 5.58 | 2 | 2 |
Lassitude
[description not available] | 0 | 3.8 | 1 | 1 |
Emesis
[description not available] | 0 | 3.8 | 1 | 1 |
Colicky Pain
[description not available] | 0 | 3.8 | 1 | 1 |
Asthenia
Clinical sign or symptom manifested as debility, or lack or loss of strength and energy. | 0 | 3.8 | 1 | 1 |
Fatigue
The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. | 0 | 3.8 | 1 | 1 |
Nausea
An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses. | 0 | 3.8 | 1 | 1 |
Vomiting
The forcible expulsion of the contents of the STOMACH through the MOUTH. | 0 | 3.8 | 1 | 1 |
Abdominal Pain
Sensation of discomfort, distress, or agony in the abdominal region. | 0 | 3.8 | 1 | 1 |
Recrudescence
[description not available] | 0 | 10.58 | 10 | 6 |
Leukocytopenia
[description not available] | 0 | 4.72 | 1 | 1 |
Leukopenia
A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000). | 0 | 4.72 | 1 | 1 |
Febrile Neutropenia
Fever accompanied by a significant reduction in the number of NEUTROPHILS. | 0 | 4.72 | 1 | 1 |
Dysmyelopoietic Syndromes
[description not available] | 0 | 2.41 | 1 | 0 |
Myelodysplastic Syndromes
Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA. | 1 | 4.41 | 1 | 0 |
Electrocardiogram QT Prolonged
[description not available] | 0 | 6.23 | 3 | 3 |
Long QT Syndrome
A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME. | 0 | 6.23 | 3 | 3 |
Acute Biphenotypic Leukemia
[description not available] | 0 | 2.25 | 1 | 0 |
Leukemia, Biphenotypic, Acute
An acute leukemia exhibiting cell features characteristic of both the myeloid and lymphoid lineages and probably arising from MULTIPOTENT STEM CELLS. | 0 | 2.25 | 1 | 0 |
Chondrosarcoma
A slowly growing malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and old people. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion or in patients with ENCHONDROMATOSIS. (Stedman, 25th ed) | 1 | 11.55 | 1 | 1 |
Hematologic Malignancies
[description not available] | 0 | 9.55 | 1 | 1 |
Hematologic Neoplasms
Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES. | 0 | 4.55 | 1 | 1 |
Leukemic Infiltration
A pathologic change in leukemia in which leukemic cells permeate various organs at any stage of the disease. All types of leukemia show various degrees of infiltration, depending upon the type of leukemia. The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest appearing in myelocytic leukemia, but infiltration is seen also in the granulocytic and lymphocytic types. The kidney is also a common site and of the gastrointestinal system, the stomach and ileum are commonly involved. In lymphocytic leukemia the skin is often infiltrated. The central nervous system too is a common site. | 0 | 2.25 | 1 | 0 |
Symptom Cluster
[description not available] | 0 | 4.33 | 3 | 0 |
Syndrome
A characteristic symptom complex. | 0 | 9.33 | 3 | 0 |
Leucocythaemia
[description not available] | 0 | 2.25 | 1 | 0 |
Acute Disease
Disease having a short and relatively severe course. | 0 | 2.69 | 2 | 0 |
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 2.25 | 1 | 0 |
Biliary Tract Cancer
[description not available] | 0 | 8.23 | 1 | 0 |
Biliary Tract Neoplasms
Tumors or cancer in the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER. | 0 | 3.23 | 1 | 0 |
Granulocytic Leukemia
[description not available] | 0 | 2.31 | 1 | 0 |
Leukemia, Myeloid
Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites. | 0 | 2.31 | 1 | 0 |
Left Ventricular Dysfunction
[description not available] | 0 | 2.31 | 1 | 0 |
Chemical Dependence
[description not available] | 0 | 2.31 | 1 | 0 |
Atherogenesis
[description not available] | 0 | 2.31 | 1 | 0 |
Co-infection
[description not available] | 0 | 2.31 | 1 | 0 |
Carcinoma, Epidermoid
[description not available] | 0 | 2.31 | 1 | 0 |
Child Development Deviations
[description not available] | 0 | 2.31 | 1 | 0 |
Cystic Fibrosis of Pancreas
[description not available] | 0 | 2.31 | 1 | 0 |
Convulsive Generalized Seizure Disorder
[description not available] | 0 | 2.31 | 1 | 0 |
Cancer of Head
[description not available] | 0 | 2.31 | 1 | 0 |
Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted
[description not available] | 0 | 2.31 | 1 | 0 |
Elevated Cholesterol
[description not available] | 0 | 2.31 | 1 | 0 |
Cancer of Larynx
[description not available] | 0 | 2.31 | 1 | 0 |
Cirrhosis, Liver
[description not available] | 0 | 2.31 | 1 | 0 |
Cancer of Lung
[description not available] | 0 | 2.31 | 1 | 0 |
Decreased Muscle Tone
[description not available] | 0 | 2.31 | 1 | 0 |
Cancer of Prostate
[description not available] | 0 | 2.31 | 1 | 0 |
HIV Coinfection
[description not available] | 0 | 2.31 | 1 | 0 |
Carcinoma, Squamous Cell
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) | 0 | 2.31 | 1 | 0 |
Developmental Disabilities
Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed) | 0 | 2.31 | 1 | 0 |
Cystic Fibrosis
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION. | 0 | 2.31 | 1 | 0 |
Head and Neck Neoplasms
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651) | 0 | 2.31 | 1 | 0 |
Hepatitis C
INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown. | 0 | 2.31 | 1 | 0 |
Hypercholesterolemia
A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population. | 0 | 2.31 | 1 | 0 |
Laryngeal Neoplasms
Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS. | 0 | 2.31 | 1 | 0 |
Liver Cirrhosis
Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. | 0 | 2.31 | 1 | 0 |
Lung Neoplasms
Tumors or cancer of the LUNG. | 0 | 2.31 | 1 | 0 |
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 3.23 | 4 | 0 |
Prostatic Neoplasms
Tumors or cancer of the PROSTATE. | 0 | 2.31 | 1 | 0 |
HIV Infections
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS). | 0 | 2.31 | 1 | 0 |
Ventricular Dysfunction, Left
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall. | 0 | 2.31 | 1 | 0 |
Substance-Related Disorders
Disorders related to substance use or abuse. | 0 | 2.31 | 1 | 0 |
Atherosclerosis
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. | 0 | 2.31 | 1 | 0 |
Refractory Anemia
[description not available] | 0 | 2.17 | 1 | 0 |
Anemia, Refractory
A severe sometimes chronic anemia, usually macrocytic in type, that does not respond to ordinary antianemic therapy. | 0 | 2.17 | 1 | 0 |
Carditis
[description not available] | 0 | 8.17 | 1 | 0 |
Shock, Cardiogenic
Shock resulting from diminution of cardiac output in heart disease. | 0 | 3.17 | 1 | 0 |
Myocarditis
Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies. | 0 | 3.17 | 1 | 0 |
Cancer of Liver
[description not available] | 0 | 2.17 | 1 | 0 |
Cancer of Pancreas
[description not available] | 0 | 2.17 | 1 | 0 |
Carcinoma, Ductal, Pancreatic
[description not available] | 0 | 2.17 | 1 | 0 |
Liver Neoplasms
Tumors or cancer of the LIVER. | 0 | 2.17 | 1 | 0 |
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). | 0 | 2.17 | 1 | 0 |
Carcinoma, Pancreatic Ductal
Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS. | 1 | 4.17 | 1 | 0 |