| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|
| stavudine | [no description available] | medium | 1 | 0 | dihydrofuran;
nucleoside analogue;
organic molecular entity | antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor |
| zalcitabine | [no description available] | medium | 2 | 0 | pyrimidine 2',3'-dideoxyribonucleoside | antimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor |
| zidovudine | [no description available] | medium | 1 | 0 | azide;
pyrimidine 2',3'-dideoxyribonucleoside | antimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor |
| 3'-azido-2',3'-dideoxyuridine | [no description available] | medium | 1 | 0 | | |
| 2',3'-dideoxycytidinene | [no description available] | medium | 1 | 0 | | |
| 3'-azido-2',3'-dideoxy-5-bromouridine | [no description available] | medium | 1 | 0 | | |
| 3'-azido-2',3'-dideoxy-5-methylcytidine | [no description available] | medium | 1 | 0 | | |
| 2',3'-dideoxythymidine | [no description available] | medium | 1 | 0 | | |
| 2',3'-didehydro-2',3'-dideoxyuridine | [no description available] | medium | 1 | 0 | | |
| 2',3'-dideoxyuridine | [no description available] | medium | 1 | 0 | pyrimidine 2',3'-dideoxyribonucleoside | |
| 5'-amino-2',5'-dideoxythymidine | [no description available] | medium | 1 | 0 | | |
| 3'-amino-2',3'-dideoxythymidine | [no description available] | medium | 1 | 0 | | |
| 3'-azido-2',3'-dideoxycytidine | [no description available] | medium | 1 | 0 | | |
| dideoxyadenosine | [no description available] | medium | 1 | 0 | adenosines;
purine 2',3'-dideoxyribonucleoside | EC 3.5.4.4 (adenosine deaminase) inhibitor;
EC 4.6.1.1 (adenylate cyclase) inhibitor |
| lamivudine | [no description available] | medium | 1 | 0 | monothioacetal;
nucleoside analogue;
oxacycle;
primary alcohol | allergen;
anti-HBV agent;
antiviral drug;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor;
HIV-1 reverse transcriptase inhibitor;
prodrug |
| 2,6-diaminopurine 2',3'-dideoxyriboside | [no description available] | medium | 1 | 0 | | |
| clarithromycin | [no description available] | medium | 1 | 0 | macrolide antibiotic | antibacterial drug;
environmental contaminant;
protein synthesis inhibitor;
xenobiotic |
| rifampin | [no description available] | medium | 1 | 0 | cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion | angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor |
| 2',3'-dideoxyguanosine | [no description available] | medium | 1 | 0 | | |
| mimosine | [no description available] | medium | 1 | 0 | alpha-amino acid | |
| bromodeoxyuridine | [no description available] | medium | 2 | 0 | pyrimidine 2'-deoxyribonucleoside | antimetabolite;
antineoplastic agent |
| biotin | [no description available] | medium | 1 | 0 | biotins;
vitamin B7 | coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite |
| biotin-16-dutp | [no description available] | medium | 1 | 0 | | |
| n-methylaspartate | [no description available] | medium | 1 | 0 | amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound | neurotransmitter agent |
| 2-amino-5-phosphonovalerate | [no description available] | medium | 1 | 0 | non-proteinogenic alpha-amino acid | NMDA receptor antagonist |
| dizocilpine maleate | [no description available] | medium | 1 | 0 | maleate salt;
tetracyclic antidepressant | anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist |
| picrotoxin | [no description available] | medium | 1 | 0 | | |
| gamma-aminobutyric acid | [no description available] | medium | 1 | 0 | amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid | human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule |
| bicuculline | [no description available] | medium | 1 | 0 | benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines | agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin |
| glutamic acid | [no description available] | medium | 1 | 0 | glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical |
| hydroxyurea | [no description available] | medium | 1 | 0 | one-carbon compound;
ureas | antimetabolite;
antimitotic;
antineoplastic agent;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
genotoxin;
immunomodulator;
radical scavenger;
teratogenic agent |
| corticosterone | [no description available] | medium | 1 | 0 | 11beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone | human metabolite;
mouse metabolite |