| Assay ID | Title | Year | Journal | Article |
|---|
| AID125177 | In vitro inhibitory activity against Moloney murine leukemia virus (M-MULV) replication, a mammalian T-lymphotropic retrovirus | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2
| Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses. |
| AID235875 | Ratio of CD50 to ED50 rvaluated for inhibition of HIV replication in MT-4 cells | 1988 | Journal of medicinal chemistry, Oct, Volume: 31, Issue:10
| Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides. |
| AID81438 | Dose required to inhibit cytopathic effect of human immunodeficiency virus replication in MT-4 cells. | 1988 | Journal of medicinal chemistry, Oct, Volume: 31, Issue:10
| Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides. |
| AID105758 | Protection was determined by evaluation of cluster morphology and reclustering properties in mock infected MT-4 cells at 5 uM concentration; Range is 40-60 | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8
| 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents. |
| AID201886 | In vitro inhibition against replication of Sarcoma-80 cells; inactive | 1983 | Journal of medicinal chemistry, Dec, Volume: 26, Issue:12
| Synthesis and biological activity of various 3'-azido and 3'-amino analogues of 5-substituted pyrimidine deoxyribonucleosides. |
| AID210869 | Inhibitory activity against thymidine kinase (TK) from L1210 cells | 1983 | Journal of medicinal chemistry, Dec, Volume: 26, Issue:12
| Synthesis and biological activity of various 3'-azido and 3'-amino analogues of 5-substituted pyrimidine deoxyribonucleosides. |
| AID56582 | Inhibitory activity against deoxycytidine kinase from L1210 cells | 1983 | Journal of medicinal chemistry, Dec, Volume: 26, Issue:12
| Synthesis and biological activity of various 3'-azido and 3'-amino analogues of 5-substituted pyrimidine deoxyribonucleosides. |
| AID105766 | Toxicity was determined by evaluation of cluster morphology and reclustering properties in mock infected MT-4 cells at 5 uM concentration | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8
| 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents. |
| AID105751 | Protection was determined by evaluation of cluster morphology and reclustering properties in mock infected MT-4 cells at 0.2 uM concentration; Range is 10-40 | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8
| 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents. |
| AID105762 | Toxicity was determined by evaluation of cluster morphology and reclustering properties in mock infected MT-4 cells at 0.2 uM concentration | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8
| 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents. |
| AID154963 | Antiviral activity against HIV I strain (LAV) in human peripheral blood mononuclear (PBM) cells; Range is 0.081 - 0.22 | 1989 | Journal of medicinal chemistry, Mar, Volume: 32, Issue:3
| Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells. |
| AID81069 | Cytotoxic dose required to reduce the viability of normal uninfected MT-4 cells. | 1988 | Journal of medicinal chemistry, Oct, Volume: 31, Issue:10
| Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides. |
| AID105753 | Protection was determined by evaluation of cluster morphology and reclustering properties in mock infected MT-4 cells at 125 uM concentration | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8
| 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents. |
| AID98047 | In vitro inhibition against replication of L1210 murine cells; inactive | 1983 | Journal of medicinal chemistry, Dec, Volume: 26, Issue:12
| Synthesis and biological activity of various 3'-azido and 3'-amino analogues of 5-substituted pyrimidine deoxyribonucleosides. |
| AID105765 | Toxicity was determined by evaluation of cluster morphology and reclustering properties in mock infected MT-4 cells at 125 uM concentration; Range is 10-40 | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8
| 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents. |
| AID81411 | Inhibition of HIV-1 replication in human peripheral blood mononuclear cells. | 1988 | Journal of medicinal chemistry, Feb, Volume: 31, Issue:2
| Synthesis and antiviral activity of various 3'-azido analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1, HTLV-III/LAV). |
| AID32065 | Protection of ATH8 cells against the cytopathic effect of HIV. | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8
| 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents. |
| AID152642 | Cytotoxic effect in uninfected human peripheral blood mononuclear (PBM) cells | 1989 | Journal of medicinal chemistry, Mar, Volume: 32, Issue:3
| Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells. |
| AID32066 | Required dose to reduce viability of normal uninfected ATH8 cells. | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8
| 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |