| Assay ID | Title | Year | Journal | Article |
|---|
| AID665498 | Induction of apoptosis in human A549 cells assessed as viable cells at 1 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis ( Rvb = 95.96%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID665494 | Cytotoxicity against human QGY7701 cells by after 48 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID729563 | Inhibition of human carbonic anhydrase 1 preincubated for 6 hrs by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| Natural product coumarins that inhibit human carbonic anhydrases. |
| AID729559 | Inhibition of human carbonic anhydrase 12 preincubated for 6 hrs by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| Natural product coumarins that inhibit human carbonic anhydrases. |
| AID225074 | Inhibitory effect on the proliferation of murine mammary carcinoma FM3A cells | 1992 | Journal of medicinal chemistry, May-15, Volume: 35, Issue:10
| Geiparvarin analogues. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain. |
| AID665511 | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 8 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis ( Rvb = 0.15%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID729560 | Inhibition of human carbonic anhydrase 9 preincubated for 6 hrs by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| Natural product coumarins that inhibit human carbonic anhydrases. |
| AID665499 | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 1 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis ( Rvb = 0.15%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID665495 | Cytotoxicity against human SW480 cells by after 48 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID47468 | Ability to inhibit human CEM tumor cell proliferation by 50% | 1989 | Journal of medicinal chemistry, Feb, Volume: 32, Issue:2
| Synthesis and cytostatic activity of geiparvarin analogues. |
| AID665491 | Cytotoxicity against human L02 cells by after 48 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID665509 | Induction of apoptosis in human A549 cells assessed as viable cells at 4 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis (Rvb = 3.72%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID221971 | Inhibitory effect on the proliferation of human T-lymphocyte MT-4 cells. | 1992 | Journal of medicinal chemistry, May-15, Volume: 35, Issue:10
| Geiparvarin analogues. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain. |
| AID665503 | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 2 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis ( Rvb = 0.15%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID125492 | Ability to inhibit human Molt/4F tumor cell proliferation by 50% | 1989 | Journal of medicinal chemistry, Feb, Volume: 32, Issue:2
| Synthesis and cytostatic activity of geiparvarin analogues. |
| AID729558 | Inhibition of human carbonic anhydrase 13 preincubated for 6 hrs by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| Natural product coumarins that inhibit human carbonic anhydrases. |
| AID665500 | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 1 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis (Rvb = 0.16%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID665502 | Induction of apoptosis in human A549 cells assessed as viable cells at 2 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis ( Rvb = 95.96%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID665504 | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 2 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis (Rvb = 0.16%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID729562 | Inhibition of human carbonic anhydrase 2 preincubated for 6 hrs by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| Natural product coumarins that inhibit human carbonic anhydrases. |
| AID165914 | Ability to inhibit human Raji tumor cell proliferation by 50% | 1989 | Journal of medicinal chemistry, Feb, Volume: 32, Issue:2
| Synthesis and cytostatic activity of geiparvarin analogues. |
| AID15873 | Partition coefficient of compound was determined | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24
| Natural and synthetic geiparvarins are strong and selective MAO-B inhibitors. Synthesis and SAR studies. |
| AID665497 | Cytotoxicity against human MDA-MB-231 cells by after 48 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID221801 | Inhibitory effect on the proliferation of human B-lymphoblast Raji cells. | 1992 | Journal of medicinal chemistry, May-15, Volume: 35, Issue:10
| Geiparvarin analogues. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain. |
| AID72034 | Ability to inhibit murine FM3A tumor cell proliferation by 50% | 1989 | Journal of medicinal chemistry, Feb, Volume: 32, Issue:2
| Synthesis and cytostatic activity of geiparvarin analogues. |
| AID79135 | Ability to inhibit human H9 tumor cell proliferation by 50% | 1989 | Journal of medicinal chemistry, Feb, Volume: 32, Issue:2
| Synthesis and cytostatic activity of geiparvarin analogues. |
| AID665501 | Induction of apoptosis in human A549 cells assessed as viable cells at 1 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis (Rvb = 3.72%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID665512 | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 8 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis (Rvb = 0.16%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID225051 | Inhibitory effect on the proliferation of murine leukemia L1210 cells. | 1992 | Journal of medicinal chemistry, May-15, Volume: 35, Issue:10
| Geiparvarin analogues. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain. |
| AID98701 | Ability to inhibit murine L1210 tumor cell proliferation by 50% | 1989 | Journal of medicinal chemistry, Feb, Volume: 32, Issue:2
| Synthesis and cytostatic activity of geiparvarin analogues. |
| AID665508 | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 4 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis (Rvb = 0.16%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID665513 | Induction of apoptosis in human A549 cells assessed as viable cells at 8 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis (Rvb = 3.72%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID127195 | Inhibitory potency against Monoamine oxidase B | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24
| Natural and synthetic geiparvarins are strong and selective MAO-B inhibitors. Synthesis and SAR studies. |
| AID665510 | Induction of apoptosis in human A549 cells assessed as viable cells at 8 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis ( Rvb = 95.96%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID210309 | Inhibitory effect on the proliferation of T-lymphoblast molt/4F cells. | 1992 | Journal of medicinal chemistry, May-15, Volume: 35, Issue:10
| Geiparvarin analogues. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain. |
| AID665496 | Cytotoxicity against human SGC7901 cells by after 48 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID665492 | Cytotoxicity against human A549 cells by after 48 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID729561 | Inhibition of human carbonic anhydrase 7 preincubated for 6 hrs by CO2 hydration stopped-flow assay | 2013 | Bioorganic & medicinal chemistry, Mar-15, Volume: 21, Issue:6
| Natural product coumarins that inhibit human carbonic anhydrases. |
| AID105737 | Ability to inhibit human MT-4 tumor cell proliferation by 50% | 1989 | Journal of medicinal chemistry, Feb, Volume: 32, Issue:2
| Synthesis and cytostatic activity of geiparvarin analogues. |
| AID665505 | Induction of apoptosis in human A549 cells assessed as viable cells at 2 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis (Rvb = 3.72%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID665493 | Cytotoxicity against human HeLa cells by after 48 hrs by MTT assay | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID665506 | Induction of apoptosis in human A549 cells assessed as viable cells at 4 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis ( Rvb = 95.96%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID665507 | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 4 uM after 48 hrs by annexinV/propidium iodide staining-based flow cytometric analysis ( Rvb = 0.15%) | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry. |
| AID126361 | Inhibitory potency against Monoamine oxidase A | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24
| Natural and synthetic geiparvarins are strong and selective MAO-B inhibitors. Synthesis and SAR studies. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |