Page last updated: 2024-12-06

thallium sulfate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

thallium sulfate: RN given refers to unspecified Tl salt [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

thallium sulfate : A metal sulfate in which the counterion is thallium and the ratio of thallium to sulfate is 2:1. It is a rodenticide used to control rats, squirrels, mice, moles, prairie dogs, ants and cockroaches. It is no longer registered for pesticide use in the United States. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID24833
CHEBI ID81836
MeSH IDM0061680

Synonyms (50)

Synonym
thallous sulfate
thallium(i) sulfate
thallium sulfate
7446-18-6
dithallium sulfate
CFS ,
sulfuric acid, thallium salt
nsc 15205
m7-giftkoerner
rcra waste no. p115
bonide antzix
hsdb 6057
rcra waste number p115
hsdb 6289
na1707
caswell no. 849
thallium sulfate, solid (dot)
sulfuric acid, thallium(1+) salt
dithallium sulphate
eccothal
thallium(1) sulfate
ccris 9169
tharattin
sulfuric acid, thallium salt (1:1)
thallium sulphate
th-universal
zelio
einecs 231-201-3
epa pesticide chemical code 080001
ai3-26193
c.f.s. (van)
C18567
10031-59-1
sulfuric acid, thallium salt (1:?)
u9f9qir12t ,
thallium sulfate, solid [na1707] [poison]
unii-u9f9qir12t
thallium sulphuricum
thallium sulfuricum
thallium(i) tetraoxosulfate
thallium sulfate [who-dd]
thallous sulphate
dithallium sulfate [hsdb]
thallium sulfate [mi]
sulfuric acid dithallium(1+) salt
CHEBI:81836
thallium (i) sulfate
DTXSID1024336
mfcd00011278
Q414866

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Instead of using death as the principal criterion of toxicity, it is based on a careful, standardized clinical assessment of toxic signs measured in the nonlethal dose range."( Acute toxicity testing in the nonlethal dose range: a new approach.
Sigg, H; Tamborini, P; Zbinden, G, 1990
)
0.28
" Combined administration of the two most toxic metals at their LC50's showed that their toxicities were not additive or synergistic."( Cytotoxicity of heavy metals in the human small intestinal epithelial cell line I-407: the role of glutathione.
Keogh, JP; Siegers, CP; Steffen, B, 1994
)
0.29
"Thallium (Tl) is a toxic heavy metal and its exposure to the human body causes physiological and biochemical changes due to its interference with potassium-dependent biological reactions."( Study of acute biochemical effects of thallium toxicity in mouse urine by NMR spectroscopy.
Bhatnagar, D; Chaturvedi, S; Devi, MM; Khan, AR; Khushu, S; Rana, P; Tripathi, RP; Tyagi, R, 2011
)
0.37

Pharmacokinetics

ExcerptReferenceRelevance
" The most important pharmacokinetic parameters which changed with the dose were Vdl (0."( [Acute pharmacokinetics of the Tl+ ion in the rabbit. 3-compartment model].
Careaga Olivares, J; Morales-Aguilera, A,
)
0.13
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
rodenticideA substance used to destroy rodent pests.
insecticideStrictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
thallium molecular entity
metal sulfateSulfate salts where the cation is a metal ion.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (30)

TimeframeStudies, This Drug (%)All Drugs %
pre-199012 (40.00)18.7374
1990's10 (33.33)18.2507
2000's3 (10.00)29.6817
2010's3 (10.00)24.3611
2020's2 (6.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 41.67

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index41.67 (24.57)
Research Supply Index3.64 (2.92)
Research Growth Index4.53 (4.65)
Search Engine Demand Index61.55 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (41.67)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies9 (24.32%)4.05%
Observational0 (0.00%)0.25%
Other28 (75.68%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]