| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1714234 | Cytotoxicity against human Huh7.5 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | 2016 | Journal of medicinal chemistry, 11-23, Volume: 59, Issue:22
| Design and Synthesis of Cajanine Analogues against Hepatitis C Virus through Down-Regulating Host Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1. |
| AID1231740 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced IL8 gene expression at 10 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1437923 | Antibacterial activity against Mycobacterium tuberculosis by broth microdilution method | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1
| Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa. |
| AID1437922 | Antibacterial activity against Enterococcus faecium ATCC 700221 by broth microdilution method | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1
| Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa. |
| AID1231744 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced MIP-3alpha gene expression at 10 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1437918 | Antibacterial activity against methicilin-resistant Staphylococcus aureus ATCC 700699 by broth microdilution method | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1
| Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa. |
| AID1437926 | Cytotoxicity against human THP1 cells after 48 hrs by resazurin dye-based fluorescence analysis | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1
| Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa. |
| AID1231371 | Activity at human PPARgamma transfected in HEK293 cells assessed as transactivation activity by luciferase reporter gene assay | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Peroxisome Proliferator-Activated Receptor γ (PPARγ) and Ligand Choreography: Newcomers Take the Stage. |
| AID1437924 | Antibacterial activity against Acinetobacter baumannii ATCC BAA1605 by broth microdilution method | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1
| Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa. |
| AID731521 | Binding affinity to human PPARalpha (unknown origin) by competitive TR-FRET assay | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. |
| AID391883 | Inhibition of TNF-alpha-induced NF-kappaB activation in human HeLa cells by SEAP reporter gene assay | 2008 | Journal of natural products, Oct, Volume: 71, Issue:10
| Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. |
| AID1231752 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced IL8 gene expression in PPARgamma knockdown human HT29 cells at 10 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1231754 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced COX2 gene expression in PPARgamma knockdown human HT29 cells at 10 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID391884 | Inhibition of LPS-induced NF-kappaB activation in mouse RAW264.7 cells by SEAP reporter gene assay | 2008 | Journal of natural products, Oct, Volume: 71, Issue:10
| Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. |
| AID1231742 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced GROgamma gene expression at 10 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1231758 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in TNFalpha-induced GRO-alpha gene expression in at 10 uM after 48 hrs by ELISA | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1437921 | Antibacterial activity against Enterococcus faecium ATCC 35667 by broth microdilution method | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1
| Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa. |
| AID731520 | Binding affinity to human PPARdelta (unknown origin) by competitive TR-FRET assay | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. |
| AID731518 | Agonist at human PPARgamma LBD expressed in human HEK293 cells cotransfected with GAL4-Luc assessed as transcriptional activation by luciferase reporter gene assay | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. |
| AID391887 | Suppression of TNF-alpha-induced expression of iNOS in human MCF7 cells at 10 uM by Western blot analysis | 2008 | Journal of natural products, Oct, Volume: 71, Issue:10
| Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. |
| AID1714233 | Antiviral activity against HCV subtype 2a J6/JFH/JC1 infected in human Huh7.5 cells assessed as reduction in viral RNA levels measured after 72 hrs by qRT-PCR analysis | 2016 | Journal of medicinal chemistry, 11-23, Volume: 59, Issue:22
| Design and Synthesis of Cajanine Analogues against Hepatitis C Virus through Down-Regulating Host Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1. |
| AID1437917 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by broth microdilution method | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1
| Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa. |
| AID731519 | Binding affinity to human PPARgamma (unknown origin) by competitive TR-FRET assay | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. |
| AID391885 | Inhibition of TNF-alpha-induced NF-kappaB DNA binding activity in human MCF7 cells by electrophoretic shift mobility assay | 2008 | Journal of natural products, Oct, Volume: 71, Issue:10
| Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. |
| AID1437927 | Cytotoxicity against mouse L5178Y cells by MTT assay | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1
| Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa. |
| AID1231743 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced IL-1beta gene expression at 10 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID391886 | Suppression of TNF-alpha-induced expression of iNOS in human MCF7 cells at 3 uM by Western blot analysis | 2008 | Journal of natural products, Oct, Volume: 71, Issue:10
| Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. |
| AID1231738 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced COX2 gene expression at 10 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1437920 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 by broth microdilution method | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1
| Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa. |
| AID1231757 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in TNFalpha-induced IL8 gene expression in at 10 uM after 48 hrs by ELISA | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1231741 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced MIP3alpha gene expression at 10 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1231735 | Reduction in TNFalpha-induced PPARgamma expression in human HT-29 cells after 48 hrs by Western blotting analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1231736 | Cytotoxicity against human HT-29 cells assessed as cell viability at 10 uM after 54 hrs by CytoTox-Glo assay | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1231372 | Activity at human PPARgamma transfected in HEK293 cells assessed as transactivation activity by reporter gene assay luciferase relative to rosiglitazone | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Peroxisome Proliferator-Activated Receptor γ (PPARγ) and Ligand Choreography: Newcomers Take the Stage. |
| AID1231739 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced GROalpha gene expression at 10 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1585336 | Anti-biofilm activity against Pseudomonas aeruginosa PAO1 at 50 uM after 24 hrs by crystal violet staining based assay relative to control | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1231756 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in TNFalpha-induced MIP3alpha gene expression in at 10 uM after 48 hrs by ELISA | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1231753 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced GROalpha gene expression in PPARgamma knockdown human HT29 cells at 10 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1231755 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced MIP3alpha gene expression in PPARgamma knockdown human HT29 cells at 10 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1437919 | Antibacterial activity against Enterococcus faecalis ATCC 29212 by broth microdilution method | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1
| Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa. |
| AID731517 | Agonist at human PPARgamma LBD expressed in human HEK293 cells cotransfected with GAL4-Luc assessed as transcriptional activation by luciferase reporter gene assay relative to rosiglitazone | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. |
| AID1714232 | Selectivity index, ratio of CC50 for cytotoxicity against human Huh7.5 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay to EC50 for antiviral activity against HCV genotype 2a J6/JFH/JC1 infected in human Huh7.5 cells assesse | 2016 | Journal of medicinal chemistry, 11-23, Volume: 59, Issue:22
| Design and Synthesis of Cajanine Analogues against Hepatitis C Virus through Down-Regulating Host Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |