| Assay ID | Title | Year | Journal | Article |
|---|
| AID1231746 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced GROalpha gene expression at 1 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1231748 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced MIP3alpha gene expression at 1 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1585345 | Inhibition of RhlA quorum sensing system in Pseudomonas aeruginosa PAO1 assessed as reduction in rhamnolipid production at 10 to 50 uM after 20 hrs | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID731518 | Agonist at human PPARgamma LBD expressed in human HEK293 cells cotransfected with GAL4-Luc assessed as transcriptional activation by luciferase reporter gene assay | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. |
| AID1286295 | Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay | 2016 | Journal of natural products, Jan-22, Volume: 79, Issue:1
| Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. |
| AID1585343 | Inhibition of lasB quorum sensing system in Pseudomonas aeruginosa PAO1 harboring mini-ctx-lasB-lacZ after 24 hrs by beta-galactosidase reporter gene assay | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1286291 | Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay | 2016 | Journal of natural products, Jan-22, Volume: 79, Issue:1
| Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. |
| AID1286292 | Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay relative to control | 2016 | Journal of natural products, Jan-22, Volume: 79, Issue:1
| Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. |
| AID1585341 | Inhibition of RhlA quorum sensing system in Pseudomonas aeruginosa PAO1 harboring mini-ctx-RhlA-lacZ at 50 uM after 24 hrs by beta-galactosidase reporter gene assay | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1231735 | Reduction in TNFalpha-induced PPARgamma expression in human HT-29 cells after 48 hrs by Western blotting analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1286286 | Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay relative to control | 2016 | Journal of natural products, Jan-22, Volume: 79, Issue:1
| Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. |
| AID1231734 | Agonist at human PPARgamma LBD expressed in human HEK293 cells cotransfected with GAL4-Luc assessed as transcriptional activation by luciferase reporter gene assay | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1585342 | Inhibition of RhlA quorum sensing system in Pseudomonas aeruginosa PAO1 harboring mini-ctx-RhlA-lacZ at 2.5 to 20 uM after 24 hrs by beta-galactosidase reporter gene assay | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1585347 | Inhibition of pqsA quorum sensing system in Pseudomonas aeruginosa PAO1 assessed as reduction in pyocyanin release at 10 uM after 20 hrs relative to control | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1585349 | Inhibition of pqsA quorum sensing system in Pseudomonas aeruginosa PAO1 harboring mini-ctx-pqsA-lacZ at 50 uM in presence of PQS by beta-galactosidase reporter gene assay | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1286290 | Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay | 2016 | Journal of natural products, Jan-22, Volume: 79, Issue:1
| Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. |
| AID1231747 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced IL8 gene expression at 1 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID731520 | Binding affinity to human PPARdelta (unknown origin) by competitive TR-FRET assay | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. |
| AID1585344 | Inhibition of pqsA quorum sensing system in Pseudomonas aeruginosa PAO1 harboring mini-ctx-pqsA-lacZ after 24 hrs by beta-galactosidase reporter gene assay | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1286296 | Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay relative to control | 2016 | Journal of natural products, Jan-22, Volume: 79, Issue:1
| Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. |
| AID1231737 | Cytotoxicity against human HT-29 cells assessed as cell viability up to 5 uM after 54 hrs by CytoTox-Glo assay | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1231751 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced MIP2 gene expression at 1 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1286294 | Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay relative to control | 2016 | Journal of natural products, Jan-22, Volume: 79, Issue:1
| Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. |
| AID731521 | Binding affinity to human PPARalpha (unknown origin) by competitive TR-FRET assay | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. |
| AID1231745 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced COX2 gene expression at 1 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1585348 | Inhibition of lasB quorum sensing system in Pseudomonas aeruginosa PAO1 harboring mini-ctx-lasB-lacZ at 50 uM in presence of ODdHL by beta-galactosidase reporter gene assay | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID731519 | Binding affinity to human PPARgamma (unknown origin) by competitive TR-FRET assay | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. |
| AID1585337 | Anti-biofilm activity against Pseudomonas aeruginosa PAO1 at 1 to 50 uM after 24 hrs by crystal violet staining based assay relative to control | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID731517 | Agonist at human PPARgamma LBD expressed in human HEK293 cells cotransfected with GAL4-Luc assessed as transcriptional activation by luciferase reporter gene assay relative to rosiglitazone | 2013 | Journal of medicinal chemistry, Feb-28, Volume: 56, Issue:4
| Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. |
| AID1585336 | Anti-biofilm activity against Pseudomonas aeruginosa PAO1 at 50 uM after 24 hrs by crystal violet staining based assay relative to control | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1585340 | Toxicity in Pseudomonas aeruginosa PAO1 harboring mini-ctx-lacZ assessed as effect on beta-galactosidase activity at 2.5 to 50 uM beta-galactosidase reporter gene assay | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1585339 | Toxicity in Pseudomonas aeruginosa PAO1 assessed as growth inhibition at 1 to 50 uM after 2 to 16 hrs | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1231749 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced GROgamma gene expression at 1 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1231750 | Agonist activity at PPARgamma in human HT29 cells assessed as reduction in in TNFalpha-induced IL-1beta gene expression at 1 uM after 48 hrs by real-time qPCR analysis | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties. |
| AID1585346 | Inhibition of lasB quorum sensing system in Pseudomonas aeruginosa PAO1 assessed as reduction in elastase release at 10 uM after 24 hrs relative to control | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1585338 | Anti-biofilm activity against Pseudomonas aeruginosa PAO1 after 24 hrs by crystal violet staining based assay | 2018 | Journal of natural products, 12-28, Volume: 81, Issue:12
| Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System. |
| AID1286293 | Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay | 2016 | Journal of natural products, Jan-22, Volume: 79, Issue:1
| Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |