| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| thioredoxin reductase | 2 | 0 | 0 | 2 |
| ATAD5 protein, partial | 3 | 0 | 0 | 3 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| Microtubule-associated protein tau | 4 | 0 | 0 | 4 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 6 | 0 | 0 | 6 |
| Bloom syndrome protein isoform 1 | 3 | 0 | 0 | 3 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 4 | 0 | 0 | 4 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| USP1 protein, partial | 3 | 0 | 0 | 3 |
| glucocorticoid receptor [Homo sapiens] | 1 | 0 | 0 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| estrogen nuclear receptor alpha | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
| geminin | 5 | 0 | 0 | 5 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| Cellular tumor antigen p53 | 1 | 0 | 0 | 1 |
| Lactoperoxidase | 0 | 1 | 0 | 1 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| Alpha-1B adrenergic receptor | 0 | 0 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | 2 | 0 | 0 | 2 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 2 | 0 | 0 | 2 |
| cytochrome P450 2C9 precursor | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 | 3 | 0 | 0 | 3 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
| Alpha-2A adrenergic receptor | 0 | 1 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
| Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
| Alpha-2C adrenergic receptor | 0 | 1 | 1 | 2 |
| Alpha-2B adrenergic receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
| Alpha-2C adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
| Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
| GABA theta subunit | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 2 | 0 | 0 | 2 |
| Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 2 | 0 | 0 | 2 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 3 | 0 | 0 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
| Luciferase | 1 | 0 | 0 | 1 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 2 | 0 | 0 | 2 |
| RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
| GLS protein | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| AR protein | 1 | 0 | 0 | 1 |
| apical membrane antigen 1, AMA1 | 3 | 0 | 0 | 3 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| progesterone receptor | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 1 | 0 | 0 | 1 |
| G | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| Parkin | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| alpha-galactosidase | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 1 precursor | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| phosphoethanolamine/phosphocholine phosphatase isoform 1 | 0 | 1 | 0 | 1 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 2 precursor | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 2 | 0 | 0 | 2 |
| serine/threonine-protein kinase PLK1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | 0 | 1 | 0 | 1 |
| Interferon beta | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit alpha-1 | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit beta-1 | 0 | 1 | 0 | 1 |
| Amyloid-beta precursor protein | 1 | 0 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Microtubule-associated protein tau | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit alpha-3 | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit beta-2 | 0 | 1 | 0 | 1 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| Indoleamine 2,3-dioxygenase 1 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | 1 | 0 | 0 | 1 |
| Fatty acid synthase | 0 | 2 | 0 | 2 |
| Sodium/potassium-transporting ATPase subunit alpha-2 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit beta-3 | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit gamma | 0 | 1 | 0 | 1 |
| WD repeat-containing protein 5 | 0 | 1 | 0 | 1 |
| Histone-lysine N-methyltransferase 2A | 0 | 1 | 0 | 1 |
| Sodium/potassium-transporting ATPase subunit alpha-4 | 0 | 1 | 0 | 1 |
| Cytosolic endo-beta-N-acetylglucosaminidase | 0 | 1 | 0 | 1 |
| Indoleamine 2,3-dioxygenase 2 | 0 | 1 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| ATP-dependent phosphofructokinase | 3 | 0 | 0 | 3 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| GALC protein | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| thyrotropin-releasing hormone receptor | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
| galanin receptor type 3 | 0 | 1 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
| Opioid receptor, delta 1b | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Opioid receptor homologue | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Acyl-CoA desaturase 1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M4 | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 1 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 1 | 0 | 1 |
| Translocator protein | 0 | 0 | 1 | 1 |
| Histidine decarboxylase | 0 | 0 | 1 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Proteinase-activated receptor 1 | 0 | 1 | 1 | 2 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| Delta-type opioid receptor | 0 | 1 | 0 | 2 |
| Delta-type opioid receptor | 0 | 2 | 1 | 4 |
| Kappa-type opioid receptor | 0 | 2 | 1 | 4 |
| Mu-type opioid receptor | 0 | 2 | 1 | 6 |
| Kappa-type opioid receptor | 0 | 2 | 1 | 4 |
| Mu-type opioid receptor | 0 | 2 | 1 | 4 |
| UDP-glucuronosyltransferase 1A3 | 0 | 0 | 0 | 1 |
| Delta-type opioid receptor | 0 | 2 | 1 | 4 |
| Kappa-type opioid receptor | 0 | 2 | 0 | 2 |
| Kappa-type opioid receptor | 0 | 2 | 1 | 4 |
| Mu-type opioid receptor | 0 | 2 | 1 | 5 |
| Nociceptin receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 2 | 0 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Beta-2 adrenergic receptor | 0 | 1 | 0 | 1 |
| Mas-related G-protein coupled receptor member X2 | 0 | 0 | 1 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| importin subunit beta-1 isoform 1 | 2 | 0 | 0 | 2 |
| snurportin-1 | 2 | 0 | 0 | 2 |
| GTP-binding nuclear protein Ran isoform 1 | 1 | 0 | 0 | 1 |
| WRN | 1 | 0 | 0 | 1 |
| MPI protein | 0 | 1 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| 67.9K protein | 1 | 0 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| serine-protein kinase ATM isoform a | 1 | 0 | 0 | 1 |
| galactokinase | 1 | 0 | 0 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
| DNA polymerase eta isoform 1 | 1 | 0 | 0 | 1 |
| protein-arginine deiminase type-4 | 0 | 1 | 0 | 1 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| Vif | 0 | 1 | 0 | 1 |
| Tat | 0 | 1 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 1 | 0 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 0 | 1 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 0 | 1 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| DNA repair and recombination protein RAD54-like | 0 | 0 | 1 | 1 |
| Sentrin-specific protease 6 | 0 | 1 | 0 | 1 |
| Sentrin-specific protease 2 | 0 | 1 | 0 | 1 |
| Sentrin-specific protease 1 | 0 | 1 | 0 | 1 |
| Protein-arginine deiminase type-1 | 0 | 1 | 0 | 1 |
| Protein-arginine deiminase type-3 | 0 | 1 | 0 | 1 |
| Protein-arginine deiminase type-4 | 0 | 1 | 0 | 1 |
| Protein-arginine deiminase type-2 | 0 | 1 | 0 | 1 |
| phosphoglycerate kinase | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |