Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
5-hydroxytryptamine receptor 2C | 0 | 2 | 2 | 4 |
5-hydroxytryptamine receptor 2A | 0 | 2 | 2 | 4 |
5-hydroxytryptamine receptor 1A | 0 | 1 | 2 | 3 |
Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
Sodium-dependent dopamine transporter | 0 | 0 | 1 | 1 |
5-hydroxytryptamine receptor 1B | 0 | 2 | 2 | 4 |
5-hydroxytryptamine receptor 1D | 0 | 1 | 2 | 3 |
5-hydroxytryptamine receptor 1F | 0 | 1 | 2 | 3 |
5-hydroxytryptamine receptor 2B | 0 | 2 | 2 | 4 |
5-hydroxytryptamine receptor 6 | 0 | 0 | 2 | 2 |
Sodium-dependent serotonin transporter | 0 | 2 | 2 | 4 |
Sodium-dependent serotonin transporter | 0 | 2 | 1 | 3 |
5-hydroxytryptamine receptor 7 | 0 | 0 | 2 | 2 |
5-hydroxytryptamine receptor 5A | 0 | 0 | 2 | 2 |
5-hydroxytryptamine receptor 5B | 0 | 0 | 2 | 2 |
5-hydroxytryptamine receptor 3A | 0 | 0 | 2 | 2 |
Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
5-hydroxytryptamine receptor 4 | 0 | 0 | 2 | 2 |
5-hydroxytryptamine receptor 3B | 0 | 0 | 2 | 2 |
TDP1 protein | 4 | 0 | 0 | 4 |
AR protein | 7 | 0 | 0 | 7 |
glucocorticoid receptor [Homo sapiens] | 6 | 0 | 0 | 6 |
estrogen nuclear receptor alpha | 8 | 0 | 0 | 8 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 6 | 0 | 0 | 6 |
nuclear receptor subfamily 1, group I, member 2 | 3 | 0 | 0 | 3 |
Chain A, Beta-lactamase | 3 | 0 | 0 | 3 |
Chain A, Cruzipain | 2 | 0 | 0 | 2 |
thioredoxin reductase | 1 | 0 | 0 | 1 |
pregnane X receptor | 2 | 0 | 0 | 2 |
RAR-related orphan receptor gamma | 5 | 0 | 0 | 5 |
SMAD family member 2 | 3 | 0 | 0 | 3 |
ATAD5 protein, partial | 2 | 0 | 0 | 2 |
USP1 protein, partial | 1 | 0 | 0 | 1 |
SMAD family member 3 | 3 | 0 | 0 | 3 |
GLI family zinc finger 3 | 4 | 0 | 0 | 4 |
Smad3 | 1 | 0 | 0 | 1 |
aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
nuclear receptor subfamily 1, group I, member 3 | 4 | 0 | 0 | 4 |
progesterone receptor | 5 | 0 | 0 | 5 |
cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
retinoic acid nuclear receptor alpha variant 1 | 5 | 0 | 0 | 5 |
retinoid X nuclear receptor alpha | 4 | 0 | 0 | 4 |
estrogen-related nuclear receptor alpha | 6 | 0 | 0 | 6 |
farnesoid X nuclear receptor | 3 | 0 | 0 | 3 |
pregnane X nuclear receptor | 5 | 0 | 0 | 5 |
G | 3 | 0 | 0 | 3 |
67.9K protein | 1 | 0 | 0 | 1 |
peroxisome proliferator-activated receptor delta | 3 | 0 | 0 | 3 |
peroxisome proliferator activated receptor gamma | 5 | 0 | 0 | 5 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | 5 | 0 | 0 | 5 |
aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
activating transcription factor 6 | 1 | 0 | 0 | 1 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 3 | 0 | 0 | 3 |
v-jun sarcoma virus 17 oncogene homolog (avian) | 3 | 0 | 0 | 3 |
D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 2 | 0 | 0 | 2 |
thyroid hormone receptor beta isoform 2 | 4 | 0 | 0 | 4 |
heat shock protein beta-1 | 2 | 0 | 0 | 2 |
nuclear factor erythroid 2-related factor 2 isoform 1 | 6 | 0 | 0 | 6 |
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
geminin | 2 | 0 | 0 | 2 |
peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
Interferon beta | 3 | 0 | 0 | 3 |
HLA class I histocompatibility antigen, B alpha chain | 3 | 0 | 0 | 3 |
Glucocorticoid receptor | 0 | 6 | 1 | 7 |
Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
Progesterone receptor | 0 | 3 | 1 | 4 |
Glycine receptor subunit alpha-1 | 0 | 6 | 0 | 6 |
Androgen receptor | 0 | 4 | 2 | 6 |
Androgen receptor | 0 | 6 | 0 | 6 |
Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
Glycine receptor subunit beta | 0 | 6 | 0 | 6 |
Glycine receptor subunit alpha-2 | 0 | 6 | 0 | 6 |
Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
Glycine receptor subunit alpha-3 | 0 | 6 | 0 | 6 |
Adenosine receptor A1 | 0 | 2 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
Adenosine receptor A2b | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
Adenosine receptor A2a | 0 | 1 | 0 | 1 |
Mu-type opioid receptor | 0 | 6 | 2 | 10 |
Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
Spike glycoprotein | 3 | 0 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
GABA theta subunit | 2 | 0 | 0 | 2 |
Inositol hexakisphosphate kinase 1 | 3 | 0 | 0 | 3 |
ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
Ataxin-2 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
cytochrome P450 2C9, partial | 3 | 0 | 0 | 3 |
ORF73 | 0 | 0 | 1 | 1 |
Luciferase | 2 | 0 | 0 | 2 |
hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
Histone H2A.x | 2 | 0 | 0 | 2 |
interleukin 8 | 2 | 0 | 0 | 2 |
cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
Integrin beta-3 | 1 | 0 | 0 | 1 |
Integrin alpha-IIb | 1 | 0 | 0 | 1 |
Gonadotropin-releasing hormone receptor | 0 | 1 | 0 | 1 |
Gonadotropin-releasing hormone receptor | 0 | 2 | 0 | 2 |
GALC protein | 1 | 0 | 0 | 1 |
Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
PINK1 | 2 | 0 | 0 | 2 |
Parkin | 2 | 0 | 0 | 2 |
chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
nonstructural protein 1 | 1 | 0 | 0 | 1 |
IDH1 | 1 | 0 | 0 | 1 |
euchromatic histone-lysine N-methyltransferase 2 | 1 | 0 | 0 | 1 |
transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 1 |
Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
Bile salt export pump | 0 | 2 | 0 | 2 |
Estrogen receptor | 0 | 1 | 1 | 2 |
Sex hormone-binding globulin | 0 | 0 | 1 | 1 |
Mineralocorticoid receptor | 0 | 1 | 0 | 1 |
Androgen receptor | 0 | 0 | 1 | 1 |
Glutamate receptor 2 | 1 | 0 | 0 | 1 |
Histamine H2 receptor | 0 | 2 | 0 | 2 |
Alpha-synuclein | 1 | 0 | 0 | 1 |
Aldo-keto reductase family 1 member C3 | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member C2 | 0 | 1 | 0 | 1 |
Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
Aldo-keto reductase family 1 member C1 | 0 | 1 | 0 | 1 |
Estrogen receptor beta | 0 | 1 | 1 | 2 |
Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
D(2) dopamine receptor | 0 | 1 | 0 | 1 |
Cytochrome P450 2B6 | 0 | 1 | 0 | 1 |
D(4) dopamine receptor | 0 | 1 | 0 | 1 |
D(3) dopamine receptor | 0 | 1 | 0 | 1 |
Delta-type opioid receptor | 0 | 3 | 2 | 7 |
Kappa-type opioid receptor | 0 | 3 | 1 | 7 |
Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 1 | 0 | 1 |
Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 1 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
Mas-related G-protein coupled receptor member X2 | 0 | 0 | 1 | 1 |
Aldehyde oxidase 1 | 0 | 1 | 0 | 1 |
survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
5-hydroxytryptamine receptor 3E | 0 | 1 | 0 | 1 |
cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
Cytochrome P450 2D6 | 0 | 1 | 0 | 2 |
Histidine decarboxylase | 0 | 0 | 1 | 1 |
UDP-glucuronosyltransferase 1A1 | 0 | 0 | 0 | 1 |
Delta-type opioid receptor | 0 | 2 | 1 | 4 |
Delta-type opioid receptor | 0 | 2 | 1 | 3 |
Kappa-type opioid receptor | 0 | 2 | 1 | 3 |
Mu-type opioid receptor | 0 | 2 | 1 | 3 |
Kappa-type opioid receptor | 0 | 2 | 1 | 3 |
Kappa-type opioid receptor | 0 | 2 | 0 | 3 |
Nociceptin receptor | 0 | 1 | 0 | 1 |
Mu-type opioid receptor | 0 | 2 | 1 | 4 |
5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
Mu-type opioid receptor | 0 | 2 | 1 | 4 |
5-hydroxytryptamine receptor 3D | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 3C | 0 | 1 | 0 | 1 |
UDP-glucuronosyltransferase 1A8 | 0 | 0 | 0 | 1 |
Carbonic anhydrase 1 | 0 | 1 | 0 | 1 |
Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
Carbonic anhydrase 4 | 0 | 1 | 0 | 1 |
Carbonic anhydrase | 0 | 1 | 0 | 1 |
Sodium/iodide cotransporter | 0 | 1 | 0 | 1 |
Carbonic anhydrase 15 | 0 | 1 | 0 | 1 |
Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
Vasopressin V2 receptor | 0 | 1 | 1 | 2 |
Oxytocin receptor | 0 | 2 | 2 | 4 |
Vasopressin V1a receptor | 0 | 1 | 0 | 1 |
Vasopressin V1a receptor | 0 | 2 | 1 | 3 |
Vasopressin V1b receptor | 0 | 1 | 1 | 2 |
Vasopressin V1b receptor | 0 | 1 | 0 | 1 |
Oxytocin receptor | 0 | 1 | 0 | 1 |
Oxytocin receptor | 0 | 0 | 1 | 1 |
Vasopressin V2 receptor | 0 | 1 | 0 | 1 |
thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
Caspase-7 | 1 | 0 | 0 | 1 |
caspase-3 | 1 | 0 | 0 | 1 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |