Page last updated: 2024-09-03

(tetrazol-5-yl)glycine and n-methylaspartate

(tetrazol-5-yl)glycine has been researched along with n-methylaspartate in 7 studies

Compound Research Comparison

Studies
((tetrazol-5-yl)glycine)
Trials
((tetrazol-5-yl)glycine)
Recent Studies (post-2010)
((tetrazol-5-yl)glycine)
Studies
(n-methylaspartate)
Trials
(n-methylaspartate)
Recent Studies (post-2010) (n-methylaspartate)
140110,408591,902

Protein Interaction Comparison

ProteinTaxonomy(tetrazol-5-yl)glycine (IC50)n-methylaspartate (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)5.175

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Calligaro, DO; Heinz, LJ; Lunn, WH; O'Malley, PJ; Salhoff, CR; Schoepp, DD; Vasileff, RT1
Oja, SS; Saransaari, P1
Lunn, WH; McDonald, JW; Salhoff, CR; Schoepp, DD1
Bains, JS; Ferguson, AV1
Bonaventure, N; Jardon, BL1
Duncan, GE; Farrington, JS; Inada, K; Koller, BH; Moy, SS1
An, Y; Belevych, N; Chen, Q; Herschman, H; Quan, N; Wang, Y; Zhang, H1

Other Studies

7 other study(ies) available for (tetrazol-5-yl)glycine and n-methylaspartate

ArticleYear
DL-tetrazol-5-ylglycine, a highly potent NMDA agonist: its synthesis and NMDA receptor efficacy.
    Journal of medicinal chemistry, 1992, Nov-27, Volume: 35, Issue:24

    Topics: Animals; Cell Membrane; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Hippocampus; Molecular Structure; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tetrazoles

1992
Glycine release from hippocampal slices in developing and ageing mice: modulation by glutamatergic receptors.
    Mechanisms of ageing and development, 1994, Oct-20, Volume: 76, Issue:2-3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dizocilpine Maleate; Female; Glycine; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; N-Methylaspartate; Potassium; Quisqualic Acid; Receptors, Glutamate; Tetrazoles

1994
The NMDA receptor agonist DL-(tetrazol-5-yl)glycine is a highly potent excitotoxin.
    European journal of pharmacology, 1994, Jan-03, Volume: 270, Issue:1

    Topics: Animals; Animals, Newborn; Brain; Choline O-Acetyltransferase; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glycine; Male; N-Methylaspartate; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrazoles

1994
Nitric oxide regulates NMDA-driven GABAergic inputs to type I neurones of the rat paraventricular nucleus.
    The Journal of physiology, 1997, Mar-15, Volume: 499 ( Pt 3)

    Topics: Animals; Bicuculline; Enzyme Inhibitors; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrazoles

1997
Involvement of NMDA in a plasticity phenomenon observed in the adult frog monocular optokinetic nystagmus.
    Vision research, 1997, Volume: 37, Issue:11

    Topics: Animals; Dark Adaptation; Glycine; N-Methylaspartate; Neuronal Plasticity; Nystagmus, Optokinetic; Photic Stimulation; Rana esculenta; Sensory Deprivation; Superior Colliculi; Tetrazoles; Time Factors; Vision, Monocular

1997
Assessment of NMDA receptor activation in vivo by Fos induction after challenge with the direct NMDA agonist (tetrazol-5-yl)glycine: effects of clozapine and haloperidol.
    Journal of neural transmission (Vienna, Austria : 1996), 2007, Volume: 114, Issue:7

    Topics: Animals; Clozapine; Glycine; Haloperidol; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mice, Transgenic; N-Methylaspartate; Proto-Oncogene Proteins c-fos; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tetrazoles

2007
Neuronal and nonneuronal COX-2 expression confers neurotoxic and neuroprotective phenotypes in response to excitotoxin challenge.
    Journal of neuroscience research, 2014, Volume: 92, Issue:4

    Topics: Analysis of Variance; Animals; Antigens, Differentiation; Cyclooxygenase 2; Disease Models, Animal; Gene Expression Regulation; Glycine; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Phosphopyruvate Hydratase; Tetrazoles

2014