| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
3-hydroxybutyric acid
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.. 3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics. | 2.02 | 1 | 0 | (omega-1)-hydroxy fatty acid;
3-hydroxy monocarboxylic acid;
hydroxybutyric acid | human metabolite |
indole
[no description available] | 1.99 | 1 | 0 | indole;
polycyclic heteroarene | Escherichia coli metabolite |
2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one
2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one: from maize extracts; structure given in first source. DIMBOA : A lactol that is DIBOA in which the hydrogen at position 7 is replaced by a methoxy group. It has been isolated from the maize plants. | 4.16 | 16 | 0 | aromatic ether;
benzoxazine;
cyclic hydroxamic acid;
lactol | allelochemical;
plant metabolite |
3-phenyllactic acid
3-phenyllactic acid: alpha-hydroxy analog of phenylalanine; RN given refers to cpd without isomeric designation. 3-phenyllactic acid : A 2-hydroxy monocarboxylic acid that is lactic acid in which one of the methyl hydrogens is substituted by a phenyl group. | 2.02 | 1 | 0 | 2-hydroxy monocarboxylic acid | human metabolite |
2-aminophenol
[no description available] | 3.47 | 1 | 1 | aminophenol | bacterial metabolite |
benzoxazolone
benzoxazolone: RN given refers to parent cpd; structure. 2-benzoxazolinone : A member of the class of benzoxazoles that is 2,3-dihydro-1,3-benzoxazole carrying an oxo group at position 2. | 3.12 | 5 | 0 | benzoxazole | allelochemical;
phytoalexin |
gramine
gramine : An aminoalkylindole that is indole carrying a dimethylaminomethyl substituent at postion 3. | 2.02 | 1 | 0 | aminoalkylindole;
indole alkaloid;
tertiary amino compound | antibacterial agent;
antiviral agent;
plant metabolite;
serotonergic antagonist |
4-butyrolactone
4-Butyrolactone: One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.. tetrahydrofuranone : Any oxolane having an oxo- substituent at any position on the tetrahydrofuran ring.. gamma-butyrolactone : A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2. | 3.47 | 1 | 1 | butan-4-olide | metabolite;
neurotoxin |
benzoxazoles
1,3-benzoxazole : A benzoxazole in which the benzene ring is fused to a 1,3-oxazole ring across positions 4 and 5.. benzoxazole : Compounds based on a fused 1,2- or 1,3-oxazole and benzene bicyclic ring skeleton. | 3.4 | 7 | 0 | 1,3-benzoxazoles;
mancude organic heterobicyclic parent | |
benzohydroxamic acid
[no description available] | 2.25 | 1 | 0 | | |
6-methoxybenzoxazolinone
6-methoxybenzoxazolinone: plant derivative which stimulates reproduction in Microtus montanus. 6-methoxy-2-benzoxazolinone : A 2-benzoxazolinone that is substituted by a methoxy group at position 6. | 2.42 | 2 | 0 | aromatic ether;
benzoxazole | antibacterial agent;
anticonvulsant;
antifungal agent;
muscle relaxant;
plant metabolite |
methoxuron
3-(3-chloro-4-methoxyphenyl)-1,1-dimethylurea: structure in first source. metoxuron : A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a 3-chloro-4-methoxyphenyl group while the other is substituted by two methyl groups. It is a plant growth regulator and a pre- and post-emergence herbicide used for the control of grasses and broad-leaved weeds in carrots and cereals (e.g. wheat, barley and rye). | 2.03 | 1 | 0 | 3-(3,4-substituted-phenyl)-1,1-dimethylurea;
monochlorobenzenes;
monomethoxybenzene | agrochemical;
environmental contaminant;
herbicide;
photosystem-II inhibitor;
plant growth regulator;
xenobiotic |
glucose, (beta-d)-isomer
beta-D-glucose : D-Glucopyranose with beta configuration at the anomeric centre.. (1->4)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->4) linkages.. (1->3)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->3) linkages. | 2.44 | 2 | 0 | D-glucopyranose | epitope;
mouse metabolite |
3-aminophenoxazone
3-aminophenoxazone: also inhibits sulfatase; structure | 2.02 | 1 | 0 | phenoxazine | |
2,3-bis(3'-hydroxybenzyl)butyrolactone
2,3-bis(3'-hydroxybenzyl)butyrolactone: lignan isolated from urine of humans & other mammals; RN given refers to cpd without isomeric designation; structure given in second source | 3.47 | 1 | 1 | lignan | |
2-hydroxy-7-methoxy-2h-1,4-benzoxazin-3-one
2-hydroxy-7-methoxy-2H-1,4-benzoxazin-3-one: structure given in first source | 2.74 | 3 | 0 | benzoxazine | |
3,5-dihydroxyphenylpropionic acid
3,5-dihydroxyphenylpropionic acid: structure | 3.47 | 1 | 1 | benzenes;
monocarboxylic acid | |
2-hydroxy-1,4-benzoxazin-3-one
2-hydroxy-1,4-benzoxazin-3-one: structure in first source. HBOA : A benzoxazine bearing hydroxy and oxo substituents at positions 2 and 3 respectively. | 2.73 | 3 | 0 | benzoxazine;
lactam;
lactol | allelochemical;
plant metabolite |
lignans
Lignans: A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed) | 3.47 | 1 | 1 | | |
glycosides
[no description available] | 2.73 | 3 | 0 | | |