ethametsulfuron-methyl : A methyl ester resulting from the formal condensation of the carboxy group of ethametsulfuron with methanol. A herbicide used for the control of broad-leaved weeds in oil seed rape and fodder rape. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 91756 |
| CHEMBL ID | 1885280 |
| CHEBI ID | 145553 |
| SCHEMBL ID | 55796 |
| MeSH ID | M0370692 |
| Synonym |
|---|
| AC-18018 |
| methyl 2-((4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl)benzoate (iupac) |
| benzoic acid, 2-(((((4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)-, methyl ester |
| methyl 2-(((((4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)benzoate |
| ethametsulfuron-methyl |
| dpx-a 7881 |
| methyl 2-[({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}amino)sulfonyl]benzoate |
| 97780-06-8 |
| ethametsulfuron methyl |
| NCGC00168305-01 |
| salsa |
| methyl 2-[[[[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]amino]carbonyl]amino]sulfonyl]benzoate |
| CHEBI:145553 |
| dpx-a7881 |
| muster |
| methyl 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate |
| methyl 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate |
| methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate |
| 2-[[[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]amino]-oxomethyl]sulfamoyl]benzoic acid methyl ester |
| A845751 |
| unii-c54zp2xryx |
| c54zp2xryx , |
| ethametsulfuron-methyl [iso] |
| FT-0642345 |
| AKOS015900060 |
| ethametsulfuron methyl ester |
| CHEMBL1885280 , |
| bdbm50424587 |
| SCHEMBL55796 |
| ZINJLDJMHCUBIP-UHFFFAOYSA-N |
| methyl 2-[[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)aminocarbonyl]aminosulfonyl]benzoate |
| DTXSID9034573 |
| ethametsulfuron-methyl, pestanal(r), analytical standard |
| RXF , |
| mfcd00486583 |
| AS-16176 |
| methyl 2-(n-(4-ethoxy-6-(methylamino)-1,3,5-triazin-2-ylcarbamoyl)sulfamoyl)benzoate |
| Q27275205 |
| Role | Description |
|---|---|
| herbicide | A substance used to destroy plant pests. |
| EC 2.2.1.6 (acetolactate synthase) inhibitor | An EC 2.2.1.* (transketolase/transaldolase) inhibitor that interferes with the action of acetolactate synthase (EC 2.2.1.6). |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| diamino-1,3,5-triazine | Any member of the class of 1,3,5-triazines that consists of a 1,3,5-triazine skeleton substituted by two amino groups. |
| N-sulfonylurea | A urea in which one of the hydrogens attached to a nitrogen of the urea group is replaced by a sulfonyl group. The N-sulfonylurea moiety is a key group in various herbicides, as well as in a number of antidiabetic drugs used in the management of type 2 diabetis mellitus. |
| aromatic ether | Any ether in which the oxygen is attached to at least one aryl substituent. |
| benzoate ester | Esters of benzoic acid or substituted benzoic acids. |
| methyl ester | Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| AR protein | Homo sapiens (human) | Potency | 0.0016 | 0.0002 | 21.2231 | 8,912.5098 | AID588516 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 12.5893 | 0.0054 | 28.0263 | 1,258.9301 | AID720659 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 50.1187 | 0.0237 | 23.2282 | 63.5986 | AID588541 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Acetolactate synthase catalytic subunit, mitochondrial | Saccharomyces cerevisiae S288C | Ki | 0.3460 | 0.0033 | 0.1284 | 0.4000 | AID721536 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID721538 | Antifungal activity against Candida albicans after 72 hrs by broth microdilution method | 2013 | Journal of medicinal chemistry, Jan-10, Volume: 56, Issue:1 | Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase. |
| AID721536 | Inhibition of Saccharomyces cerevisiae acetohydroxyacid synthase by colorimetric assay | 2013 | Journal of medicinal chemistry, Jan-10, Volume: 56, Issue:1 | Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase. |
| AID721535 | Inhibition of Candida albicans acetohydroxyacid synthase catalytic domain expressed in Escherichia coli by colorimetric method | 2013 | Journal of medicinal chemistry, Jan-10, Volume: 56, Issue:1 | Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase. |
| AID721539 | Antifungal activity against Saccharomyces cerevisiae after 72 hrs by broth microdilution assay | 2013 | Journal of medicinal chemistry, Jan-10, Volume: 56, Issue:1 | Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.43) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||