Compounds > ningnanmycin
Page last updated: 2024-11-13

ningnanmycin

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Description

ningnanmycin: isolated from Strepcomces noursei [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID44588235
CHEMBL ID458302
SCHEMBL ID17193751
MeSH IDM000601262

Synonyms (8)

Synonym
ningnanmycin
CHEMBL458302
ningnamycin
SCHEMBL17193751
beta-d-glucopyranuronamide, 1-(4-amino-2-oxo-1(2h)-pyrimidinyl)-1,4-dideoxy-4-[(n-methylglycyl-l-seryl)amino]-
156410-09-2
DTXSID601020469
.beta.-d-glucopyranuronamide, 1-(4-amino-2-oxo-1(2h)-pyrimidinyl)-1,4-dideoxy-4-[(n-methylglycyl-l-seryl)amino]-

Research Excerpts

Overview

Ningnanmycin (NNM) is an antiviral agent firstly isolated from Strepcomces noursei var·xichangensisn.

ExcerptReferenceRelevance
"Ningnanmycin is a new antibiotic pesticide with good bactericidal and antiviral efficacy, which is widely used in the control of fruit and vegetable diseases, and the excessive pesticide residues pose a serious threat to the environment and human health."( Detection of Ningnanmycin Using Fluorescence Spectroscopy Combined with BP Neural Network.
Bian, H; Feng, X; Han, Y; Ji, R; Jiang, Z; Wang, M; Wang, X; Xu, J; Yang, Y, 2023)		2.72
"Ningnanmycin (NNM) is an antiviral agent firstly isolated from Strepcomces noursei var·xichangensisn. "( Induction of systemic resistance against tobacco mosaic virus by Ningnanmycin in tobacco.
Du, L; Han, Y; Luo, Y; Qin, S; Wan, B; Xi, L, 2014)		2.08

Compound-Compound Interactions

ExcerptReferenceRelevance
"Studies have shown that fluorescence spectroscopy combined with BP neural network can effectively predict the concentration of ningnanmycin."( Detection of Ningnanmycin Using Fluorescence Spectroscopy Combined with BP Neural Network.
Bian, H; Feng, X; Han, Y; Ji, R; Jiang, Z; Wang, M; Wang, X; Xu, J; Yang, Y, 2023)		1.49
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (128)

Assay IDTitleYearJournalArticle
AID696757Antiviral activity against Tobacco mosaic virus infected in right side leaf of Nicotiana glutinosa at 40 uM after 3 to 4 days by half-leaf method2012Journal of natural products, Nov-26, Volume: 75, Issue:11
Antiviral chromones from the stem of Cassia siamea.
AID1081317In vivo antiviral activity against Tobacco mosaic virus strain U1 (TMV) infected left side of Nicotiana glutinosa leaves assessed as decrease in local lesion numbers at 2.5 uM co-incubated with virus for 30 min before inoculation onto leaves measured at 32010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Anti-tobacco mosaic virus (TMV) Quassinoids from Brucea javanica (L.) Merr.
AID1082830Inhibition of Tobacco mosaic virus (TMV) infection in Nicotiana glutinosa assessed as infection inhibition rate at 25 ug/ml after 3 to 4 days by half-leaf method2012Journal of agricultural and food chemistry, May-02, Volume: 60, Issue:17
The limonoids and their antitobacco mosaic virus (TMV) activities from Munronia unifoliolata Oliv.
AID696759Antiviral activity against Tobacco mosaic virus infected in right side leaf of Nicotiana glutinosa at 5 uM after 3 to 4 days by half-leaf method2012Journal of natural products, Nov-26, Volume: 75, Issue:11
Antiviral chromones from the stem of Cassia siamea.
AID1080419In vivo antiviral activity against Tobacco mosaic virus (TMV) infected left side of tobacco leaves assessed as inactivation effect at 250 ug/ml co-incubated with virus for 30 min before inoculation onto leaves measured at 3-4 days after viral challenge2008Journal of agricultural and food chemistry, Nov-12, Volume: 56, Issue:21
Synthesis and antiviral activities of pyrazole derivatives containing an oxime moiety.
AID1082877In vivo antiviral activity against Tobacco mosaic virus (TMV) inoculated left side of Nicotiana. tabacum L. leaves assessed as inactivation effect at 500 ug/mL co-incubated with virus measured after 3 to 4 days2012Journal of agricultural and food chemistry, Jun-13, Volume: 60, Issue:23
Design, synthesis, antiviral activity, and SARs of 14-aminophenanthroindolizidines.
AID1103441Antiviral activity against Tobacco mosaic virus (TMV) inoculated in whole leaves of Nicotiana tabacum L. assessed as curative effect measured as local lesion number at 500 mg/l after 3 to 4 days2005Journal of agricultural and food chemistry, Oct-05, Volume: 53, Issue:20
Synthesis and antiviral activity of novel chiral cyanoacrylate derivatives.
AID390528Antiviral activity against TMV assessed as viral disease curative effect at 500 mg/L2008Bioorganic & medicinal chemistry, Nov-15, Volume: 16, Issue:22
Synthesis and antiviral activity of novel pyrazole derivatives containing oxime esters group.
AID1080575Antiviral activity against Tobacco mosaic virus (TMV) in compound treated Nicotiana tabacum L.leaves assessed as curative effect from local lesions at 500 ug/ml measured after 3 to 4 days2009Journal of agricultural and food chemistry, Feb-25, Volume: 57, Issue:4
Synthesis and antiviral activities of chiral thiourea derivatives containing an alpha-aminophosphonate moiety.
AID1228086Antiviral activity against 30 mins compound pre-treated TMV U1 infected on Nicotiana glutinosa leaves assessed as virus inactivation effect by measuring local lesion numbers after 3 to 4 days post virus inoculation at 50 ug/ml by half-leaf method2015Journal of natural products, Apr-24, Volume: 78, Issue:4
Bioactive Limonoid Constituents of Munronia henryi.
AID1080741Antiviral activity against Tobacco mosaic virus U1 (TMV) infected Nicotiana glutinosa leaves assessed as inhibition of viral replication at 50 ug/mL in presence of 25 ug/mL quassinoid nigakilactone B measured 48 hr after compound exposure by half leaf met2009Journal of agricultural and food chemistry, Aug-12, Volume: 57, Issue:15
Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioides Benn.
AID1081811Antiviral activity against Tobacco mosaic virus (TMV) inoculated on whole Nicotiana tabacum leaves followed by smearing with 500 ug/mL compound solution on left side of leaves assessed as viral infection curative effect measured 3 to 4 days post viral inf2010Journal of agricultural and food chemistry, Dec-08, Volume: 58, Issue:23
Design, synthesis, and antiviral evaluation of phenanthrene-based tylophorine derivatives as potential antiviral agents.
AID1081815Antiviral activity against Tobacco mosaic virus (TMV) inoculated on 500 ug/mL compound smeared Nicotiana tabacum leaves assessed as protective effect against viral infection measured 3 to 4 days post viral infection2010Journal of agricultural and food chemistry, Dec-08, Volume: 58, Issue:23
Design, synthesis, and antiviral evaluation of phenanthrene-based tylophorine derivatives as potential antiviral agents.
AID696760Antiviral activity against Tobacco mosaic virus infected in right side leaf of Nicotiana glutinosa at 20 uM after 3 to 4 days by half-leaf method2012Journal of natural products, Nov-26, Volume: 75, Issue:11
Antiviral chromones from the stem of Cassia siamea.
AID390526Antiviral activity against TMV assessed as protection effect against viral infection at 500 mg/L2008Bioorganic & medicinal chemistry, Nov-15, Volume: 16, Issue:22
Synthesis and antiviral activity of novel pyrazole derivatives containing oxime esters group.
AID1080335Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 125 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Feb-13, Volume: 56, Issue:3
Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety.
AID1112993Antiviral activity against Tobacco mosaic virus (TMV) in tobacco leaf juice at 500 ug/ml after 72 hr by half-leaf method2013Journal of agricultural and food chemistry, Feb-06, Volume: 61, Issue:5
Synthesis and antiviral activities of antofine analogues with different C-6 substituent groups.
AID1082828Inhibition of Tobacco mosaic virus (TMV) infection in Nicotiana tabacum cv. K326 at 30 ug/ml by DAS-ELISA method2012Journal of agricultural and food chemistry, May-02, Volume: 60, Issue:17
The limonoids and their antitobacco mosaic virus (TMV) activities from Munronia unifoliolata Oliv.
AID1081813Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 500 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2010Journal of agricultural and food chemistry, Dec-08, Volume: 58, Issue:23
Design, synthesis, and antiviral evaluation of phenanthrene-based tylophorine derivatives as potential antiviral agents.
AID1112988Antiviral activity against Tobacco mosaic virus (TMV) in tobacco plant leaf assessed as inactivation effect at 100 ug/ml after 3 to 4 days2013Journal of agricultural and food chemistry, Feb-06, Volume: 61, Issue:5
Synthesis and antiviral activities of antofine analogues with different C-6 substituent groups.
AID1080571Antiviral activity against Tobacco mosaic virus (TMV) in compound treated Nicotiana tabacum L.leaves assessed as curative effect2009Journal of agricultural and food chemistry, Feb-25, Volume: 57, Issue:4
Synthesis and antiviral activities of chiral thiourea derivatives containing an alpha-aminophosphonate moiety.
AID1082879Antiviral activity against Tobacco mosaic virus (TMV) inoculated in 5-6 growth stage leaf assessed as inhibition effect at 500 ug/mL at 25 degC after 72 hr by half-leaf method2012Journal of agricultural and food chemistry, Jun-13, Volume: 60, Issue:23
Design, synthesis, antiviral activity, and SARs of 14-aminophenanthroindolizidines.
AID1082874In vivo antiviral activity against Tobacco mosaic virus (TMV) pre-inoculated Nicotiana. tabacum L. leaves assessed as curative effect at 100 ug/mL measured after 3 to 4 days2012Journal of agricultural and food chemistry, Jun-13, Volume: 60, Issue:23
Design, synthesis, antiviral activity, and SARs of 14-aminophenanthroindolizidines.
AID390527Antiviral activity against TMV assessed as viral inactivation effect at 500 mg/L2008Bioorganic & medicinal chemistry, Nov-15, Volume: 16, Issue:22
Synthesis and antiviral activity of novel pyrazole derivatives containing oxime esters group.
AID1092194In vivo antiviral activity against Tobacco mosaic virus (TMV) inoculated right side of Nicotiana tabacum L. leaves assessed as protection effect at 500 ug/mL preincubated 12 hr before viral challenge measured after 3 to 4 days2012Journal of agricultural and food chemistry, Oct-17, Volume: 60, Issue:41
Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of phenanthroindolizidines and their analogues.
AID1080338Antiviral activity against Tobacco mosaic virus (TMV) inoculated on whole Nicotiana tabacum leaves followed by smearing with 125 ug/mL compound solution on left side of leaves assessed as viral infection curative effect measured 3 to 4 days post viral inf2008Journal of agricultural and food chemistry, Feb-13, Volume: 56, Issue:3
Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety.
AID1228087Antiviral activity against TMV U1 infected on compound smeared Nicotiana glutinosa leaves assessed as virus infection protective effect by measuring local lesion numbers after 3 to 4 days post virus inoculation at 200 ug/ml by half-leaf method2015Journal of natural products, Apr-24, Volume: 78, Issue:4
Bioactive Limonoid Constituents of Munronia henryi.
AID1092195In vivo antiviral activity against Tobacco mosaic virus (TMV) pre-inoculated Nicotiana tabacum L. leaves assessed as curative effect at 100 ug/mL measured after 3 to 4 days2012Journal of agricultural and food chemistry, Oct-17, Volume: 60, Issue:41
Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of phenanthroindolizidines and their analogues.
AID1228092Antiviral activity against 30 mins compound pre-treated TMV U1 infected on Nicotiana glutinosa leaves assessed as virus inactivation effect by measuring local lesion numbers after 3 to 4 days post virus inoculation at 20 ug/ml by half-leaf method relative2015Journal of natural products, Apr-24, Volume: 78, Issue:4
Bioactive Limonoid Constituents of Munronia henryi.
AID1081043In vivo antiviral activity against Tobacco mosaic virus (TMV) infected left side of tobacco leaves assessed as curative effect by decreasing local lesion number at 500 mg/l treated after viral inoculation measured at 3-4 days after viral challenge2010Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5
Synthesis and antiviral bioactivities of 2-cyano-3-substituted-amino(phenyl) methylphosphonylacrylates (acrylamides) containing alkoxyethyl moieties.
AID1080337Antiviral activity against Tobacco mosaic virus (TMV) inoculated on whole Nicotiana tabacum leaves followed by smearing with compound solution on left side of leaves assessed as viral infection curative effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Feb-13, Volume: 56, Issue:3
Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety.
AID1081316In vivo antiviral activity against Tobacco mosaic virus strain U1 (TMV) infected left side of Nicotiana glutinosa leaves assessed as decrease in local lesion numbers at 5 uM co-incubated with virus for 30 min before inoculation onto leaves measured at 3-42010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Anti-tobacco mosaic virus (TMV) Quassinoids from Brucea javanica (L.) Merr.
AID1080574Antiviral activity against Tobacco mosaic virus (TMV) in compound treated Nicotiana tabacum L.leaves assessed as curative effect at 500 ug/ml2009Journal of agricultural and food chemistry, Feb-25, Volume: 57, Issue:4
Synthesis and antiviral activities of chiral thiourea derivatives containing an alpha-aminophosphonate moiety.
AID1082831Inhibition of Tobacco mosaic virus (TMV) infection in Nicotiana glutinosa assessed as infection inhibition rate at 20 ug/ml after 3 to 4 days by half-leaf method2012Journal of agricultural and food chemistry, May-02, Volume: 60, Issue:17
The limonoids and their antitobacco mosaic virus (TMV) activities from Munronia unifoliolata Oliv.
AID1080339Antiviral activity against Tobacco mosaic virus (TMV) inoculated on whole Nicotiana tabacum leaves followed by smearing with 250 ug/mL compound solution on left side of leaves assessed as viral infection curative effect measured 3 to 4 days post viral inf2008Journal of agricultural and food chemistry, Feb-13, Volume: 56, Issue:3
Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety.
AID1228091Antiviral activity against 30 mins compound pre-treated TMV U1 infected on Nicotiana glutinosa leaves assessed as virus inactivation effect by measuring local lesion numbers after 3 to 4 days post virus inoculation at 30 ug/ml by half-leaf method relative2015Journal of natural products, Apr-24, Volume: 78, Issue:4
Bioactive Limonoid Constituents of Munronia henryi.
AID1080422In vivo antiviral activity against Tobacco mosaic virus (TMV) infected left side of tobacco leaves assessed as curative effect at 500 ug/ml treated after viral inoculation measured at 3-4 days after viral challenge2008Journal of agricultural and food chemistry, Nov-12, Volume: 56, Issue:21
Synthesis and antiviral activities of pyrazole derivatives containing an oxime moiety.
AID322718Antiviral activity against TMV-infected tobacco leaves assessed as viral inactivation at 500 mg/L2008Bioorganic & medicinal chemistry, Mar-15, Volume: 16, Issue:6
Synthesis and antiviral activities of novel chiral cyanoacrylate derivatives with (E) configuration.
AID1080336Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 250 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Feb-13, Volume: 56, Issue:3
Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety.
AID1080740Antiviral activity against Tobacco mosaic virus U1 (TMV) infected Nicotiana tabacum cv. K326 leaves assessed as inhibition of viral replication at 50 ug/mL measured 48 hr after compound exposure by leaf-disk method2009Journal of agricultural and food chemistry, Aug-12, Volume: 57, Issue:15
Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioides Benn.
AID1092199Antiviral activity against Tobacco mosaic virus (TMV) inoculated in 5-6 growth stage leaf assessed as inhibition effect at 100 ug/mL at 25 degC after 72 hr by half-leaf method2012Journal of agricultural and food chemistry, Oct-17, Volume: 60, Issue:41
Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of phenanthroindolizidines and their analogues.
AID1082873In vivo antiviral activity against Tobacco mosaic virus (TMV) inoculated right side of Nicotiana. tabacum L. leaves assessed as protection effect at 500 ug/mL preincubated 12 hr before viral challenge measured after 3 to 4 days2012Journal of agricultural and food chemistry, Jun-13, Volume: 60, Issue:23
Design, synthesis, antiviral activity, and SARs of 14-aminophenanthroindolizidines.
AID1081814Antiviral activity against Tobacco mosaic virus (TMV) inoculated on 100 ug/mL compound smeared Nicotiana tabacum leaves assessed as protective effect against viral infection measured 3 to 4 days post viral infection2010Journal of agricultural and food chemistry, Dec-08, Volume: 58, Issue:23
Design, synthesis, and antiviral evaluation of phenanthrene-based tylophorine derivatives as potential antiviral agents.
AID696758Antiviral activity against Tobacco mosaic virus infected in right side leaf of Nicotiana glutinosa at 10 uM after 3 to 4 days by half-leaf method2012Journal of natural products, Nov-26, Volume: 75, Issue:11
Antiviral chromones from the stem of Cassia siamea.
AID1081042In vivo antiviral activity against Tobacco mosaic virus (TMV) infected left side of tobacco leaves assessed as inactivation effect by decreasing local lesion number at 500 mg/l co-incubated with virus for 30 min before inoculation onto leaves measured at 2010Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5
Synthesis and antiviral bioactivities of 2-cyano-3-substituted-amino(phenyl) methylphosphonylacrylates (acrylamides) containing alkoxyethyl moieties.
AID1081053Antiviral activity against Tobacco mosaic virus (TMV) inoculated on fresh tobacco leaves followed by dipping into compound solution for 20 min and measured 72 hr post compound treatment by half-leaf method2010Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5
Synthesis and antiviral activities of phenanthroindolizidine alkaloids and their derivatives.
AID1092200Antiviral activity against Tobacco mosaic virus (TMV) inoculated in 5-6 growth stage leaf assessed as inhibition effect at 500 ug/mL at 25 degC after 72 hr by half-leaf method2012Journal of agricultural and food chemistry, Oct-17, Volume: 60, Issue:41
Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of phenanthroindolizidines and their analogues.
AID696754Antiviral activity against Tobacco mosaic virus infected in right side leaf of Nicotiana glutinosa after 3 to 4 days by half-leaf method2012Journal of natural products, Nov-26, Volume: 75, Issue:11
Antiviral chromones from the stem of Cassia siamea.
AID1080738Antiviral activity against Tobacco mosaic virus U1 (TMV) infected Nicotiana glutinosa leaves assessed as inhibition of viral infection at 50 ug/mL using compound pre-treated virus suspension in presence of 25 ug/mL quassinoid nigakilactone B measured 5 to2009Journal of agricultural and food chemistry, Aug-12, Volume: 57, Issue:15
Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioides Benn.
AID1081319In vivo antiviral activity against Tobacco mosaic virus strain U1 (TMV) infected left side of Nicotiana glutinosa leaves assessed as decrease in local lesion numbers at 20 uM co-incubated with virus for 30 min before inoculation onto leaves measured at 3-2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Anti-tobacco mosaic virus (TMV) Quassinoids from Brucea javanica (L.) Merr.
AID1112990Antiviral activity against Tobacco mosaic virus (TMV) in tobacco plant leaf assessed as protection effect at 500 ug/ml after 3 to 4 days2013Journal of agricultural and food chemistry, Feb-06, Volume: 61, Issue:5
Synthesis and antiviral activities of antofine analogues with different C-6 substituent groups.
AID1082829Inhibition of Tobacco mosaic virus (TMV) infection in Nicotiana glutinosa assessed as infection inhibition rate at 30 ug/ml after 3 to 4 days by half-leaf method2012Journal of agricultural and food chemistry, May-02, Volume: 60, Issue:17
The limonoids and their antitobacco mosaic virus (TMV) activities from Munronia unifoliolata Oliv.
AID1228093Antiviral activity against 30 mins compound pre-treated TMV U1 infected on Nicotiana glutinosa leaves assessed as virus inactivation effect by measuring local lesion numbers after 3 to 4 days post virus inoculation at 10 ug/ml by half-leaf method relative2015Journal of natural products, Apr-24, Volume: 78, Issue:4
Bioactive Limonoid Constituents of Munronia henryi.
AID1080365Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 125 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and antiviral activities of cyanoacrylate derivatives containing an alpha-aminophosphonate moiety.
AID1112987Antiviral activity against Tobacco mosaic virus (TMV) in tobacco plant leaf assessed as curative effect at 500 ug/ml after 3 to 4 days2013Journal of agricultural and food chemistry, Feb-06, Volume: 61, Issue:5
Synthesis and antiviral activities of antofine analogues with different C-6 substituent groups.
AID1080369Antiviral activity against Tobacco mosaic virus (TMV) inoculated on 500 ug/mL compound smeared Nicotiana tabacum leaves assessed as protective effect against viral infection measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and antiviral activities of cyanoacrylate derivatives containing an alpha-aminophosphonate moiety.
AID1081046Antiviral activity against Tobacco mosaic virus (TMV) inoculated on fresh tobacco leaves followed by dipping into compound solution at 250 ug/mL for 20 min and measured 72 hr post compound treatment by half-leaf method2010Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5
Synthesis and antiviral activities of phenanthroindolizidine alkaloids and their derivatives.
AID1080735Antiviral activity against Tobacco mosaic virus U1 (TMV) infected Nicotiana tabacum cv. K326 leaves assessed as inhibition of viral replication in presence of 25 ug/mL quassinoid nigakilactone B measured 48 hr after compound exposure by leaf-disk method2009Journal of agricultural and food chemistry, Aug-12, Volume: 57, Issue:15
Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioides Benn.
AID1080333Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Feb-13, Volume: 56, Issue:3
Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety.
AID1082878Antiviral activity against Tobacco mosaic virus (TMV) inoculated in 5-6 growth stage leaf assessed as inhibition effect at 100 ug/mL at 25 degC after 72 hr by half-leaf method2012Journal of agricultural and food chemistry, Jun-13, Volume: 60, Issue:23
Design, synthesis, antiviral activity, and SARs of 14-aminophenanthroindolizidines.
AID1081052Antiviral activity against Tobacco mosaic virus (TMV) inoculated on 500 ug/mL compound smeared Nicotiana tabacum leaves assessed as protective effect against viral infection measured 3 to 4 days post viral infection2010Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5
Synthesis and antiviral activities of phenanthroindolizidine alkaloids and their derivatives.
AID1092196In vivo antiviral activity against Tobacco mosaic virus (TMV) pre-inoculated Nicotiana tabacum L. leaves assessed as curative effect at 500 ug/mL measured after 3 to 4 days2012Journal of agricultural and food chemistry, Oct-17, Volume: 60, Issue:41
Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of phenanthroindolizidines and their analogues.
AID1080416In vivo antiviral activity against Tobacco mosaic virus (TMV) infected left side of tobacco leaves assessed as inactivation effect at 62.5 ug/ml co-incubated with virus for 30 min before inoculation onto leaves measured at 3-4 days after viral challenge2008Journal of agricultural and food chemistry, Nov-12, Volume: 56, Issue:21
Synthesis and antiviral activities of pyrazole derivatives containing an oxime moiety.
AID1080742Antiviral activity against Tobacco mosaic virus U1 (TMV) infected Nicotiana glutinosa leaves assessed as inhibition of viral replication at 50 ug/mL measured 48 hr after compound exposure by half leaf method2009Journal of agricultural and food chemistry, Aug-12, Volume: 57, Issue:15
Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioides Benn.
AID1228089Antiviral activity against 30 mins compound pre-treated TMV U1 infected on Nicotiana glutinosa leaves assessed as virus inactivation effect by measuring local lesion numbers after 3 to 4 days post virus inoculation at 50 ug/ml by half-leaf method relative2015Journal of natural products, Apr-24, Volume: 78, Issue:4
Bioactive Limonoid Constituents of Munronia henryi.
AID732660Antiviral activity against TMV strain U1 infected in compound-pretreated Nicotiana glutinosa leaves assessed as inhibition of viral infection at 20 uM incubated with leaf for 6 hrs prior to viral inoculation2013Journal of natural products, Feb-22, Volume: 76, Issue:2
Antiviral phenolic compounds from Arundina gramnifolia.
AID1081318In vivo antiviral activity against Tobacco mosaic virus strain U1 (TMV) infected left side of Nicotiana glutinosa leaves assessed as decrease in local lesion numbers at 1.25 uM co-incubated with virus for 30 min before inoculation onto leaves measured at 2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Anti-tobacco mosaic virus (TMV) Quassinoids from Brucea javanica (L.) Merr.
AID1080421In vivo antiviral activity against Tobacco mosaic virus (TMV) infected left side of tobacco leaves assessed as protective effect at 500 ug/ml treated 12 hr before viral inoculation measured at 3-4 days after viral challenge2008Journal of agricultural and food chemistry, Nov-12, Volume: 56, Issue:21
Synthesis and antiviral activities of pyrazole derivatives containing an oxime moiety.
AID1080367Antiviral activity against Tobacco mosaic virus (TMV) inoculated on whole Nicotiana tabacum leaves followed by smearing with 500 ug/mL compound solution on left side of leaves assessed as viral infection curative effect measured 3 to 4 days post viral inf2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and antiviral activities of cyanoacrylate derivatives containing an alpha-aminophosphonate moiety.
AID1080418In vivo antiviral activity against Tobacco mosaic virus (TMV) infected left side of tobacco leaves assessed as inactivation effect at 125 ug/ml co-incubated with virus for 30 min before inoculation onto leaves measured at 3-4 days after viral challenge2008Journal of agricultural and food chemistry, Nov-12, Volume: 56, Issue:21
Synthesis and antiviral activities of pyrazole derivatives containing an oxime moiety.
AID696753Antiviral activity against Tobacco mosaic virus infected in leaf of Nicotiana glutinosa assessed as protection against viral infection at 20 uM treated 6 hrs before infection2012Journal of natural products, Nov-26, Volume: 75, Issue:11
Antiviral chromones from the stem of Cassia siamea.
AID1092197In vivo antiviral activity against Tobacco mosaic virus (TMV) inoculated left side of Nicotiana tabacum L. leaves assessed as inactivation effect at 100 ug/mL co-incubated with virus measured after 3 to 4 days2012Journal of agricultural and food chemistry, Oct-17, Volume: 60, Issue:41
Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of phenanthroindolizidines and their analogues.
AID696755Antiviral activity against Tobacco mosaic virus infected in right side leaf of Nicotiana glutinosa at 160 uM after 3 to 4 days by half-leaf method2012Journal of natural products, Nov-26, Volume: 75, Issue:11
Antiviral chromones from the stem of Cassia siamea.
AID1080368Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 500 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and antiviral activities of cyanoacrylate derivatives containing an alpha-aminophosphonate moiety.
AID1080420In vivo antiviral activity against Tobacco mosaic virus (TMV) infected left side of tobacco leaves assessed as inactivation effect at 500 ug/ml co-incubated with virus for 30 min before inoculation onto leaves measured at 3-4 days after viral challenge2008Journal of agricultural and food chemistry, Nov-12, Volume: 56, Issue:21
Synthesis and antiviral activities of pyrazole derivatives containing an oxime moiety.
AID1112986Antiviral activity against Tobacco mosaic virus (TMV) in tobacco plant leaf assessed as curative effect at 100 ug/ml after 3 to 4 days2013Journal of agricultural and food chemistry, Feb-06, Volume: 61, Issue:5
Synthesis and antiviral activities of antofine analogues with different C-6 substituent groups.
AID390530Increase in PR-1a gene expression in TMV-infected tobacco leaf assessed as gene expression ratio on day 5 by RT-PCR2008Bioorganic & medicinal chemistry, Nov-15, Volume: 16, Issue:22
Synthesis and antiviral activity of novel pyrazole derivatives containing oxime esters group.
AID1082832Inhibition of Tobacco mosaic virus (TMV) infection in Nicotiana glutinosa assessed as infection inhibition rate at 15 ug/ml after 3 to 4 days by half-leaf method2012Journal of agricultural and food chemistry, May-02, Volume: 60, Issue:17
The limonoids and their antitobacco mosaic virus (TMV) activities from Munronia unifoliolata Oliv.
AID1103443Antiviral activity against Tobacco mosaic virus (TMV) inoculated in left side of Nicotiana tabacum L. leaves assessed as inhibition of local lesion number at 500 mg/l measured after 3 to 4 days2005Journal of agricultural and food chemistry, Oct-05, Volume: 53, Issue:20
Synthesis and antiviral activity of novel chiral cyanoacrylate derivatives.
AID1080362Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and antiviral activities of cyanoacrylate derivatives containing an alpha-aminophosphonate moiety.
AID1080334Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 62.5 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Feb-13, Volume: 56, Issue:3
Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety.
AID1081044In vivo antiviral activity against Tobacco mosaic virus (TMV) infected left side of tobacco leaves assessed as protective effect by decreasing local lesion number at 500 mg/l treated 12 hr before viral inoculation measured at 3-4 days after viral challeng2010Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5
Synthesis and antiviral bioactivities of 2-cyano-3-substituted-amino(phenyl) methylphosphonylacrylates (acrylamides) containing alkoxyethyl moieties.
AID1082827Inhibition of Tobacco mosaic virus (TMV) infection in Nicotiana glutinosa at 200 ug/ml after 3 to 4 days by half-leaf method2012Journal of agricultural and food chemistry, May-02, Volume: 60, Issue:17
The limonoids and their antitobacco mosaic virus (TMV) activities from Munronia unifoliolata Oliv.
AID1080363Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 30.7 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and antiviral activities of cyanoacrylate derivatives containing an alpha-aminophosphonate moiety.
AID1092198In vivo antiviral activity against Tobacco mosaic virus (TMV) inoculated left side of Nicotiana tabacum L. leaves assessed as inactivation effect at 500 ug/mL co-incubated with virus measured after 3 to 4 days2012Journal of agricultural and food chemistry, Oct-17, Volume: 60, Issue:41
Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of phenanthroindolizidines and their analogues.
AID1081810Antiviral activity against Tobacco mosaic virus (TMV) inoculated on whole Nicotiana tabacum leaves followed by smearing with 100 ug/mL compound solution on left side of leaves assessed as viral infection curative effect measured 3 to 4 days post viral inf2010Journal of agricultural and food chemistry, Dec-08, Volume: 58, Issue:23
Design, synthesis, and antiviral evaluation of phenanthrene-based tylophorine derivatives as potential antiviral agents.
AID1112992Antiviral activity against Tobacco mosaic virus (TMV) in tobacco leaf juice at 100 ug/ml after 72 hr by half-leaf method2013Journal of agricultural and food chemistry, Feb-06, Volume: 61, Issue:5
Synthesis and antiviral activities of antofine analogues with different C-6 substituent groups.
AID1081045Antiviral activity against Tobacco mosaic virus (TMV) inoculated on fresh tobacco leaves followed by dipping into compound solution at 125 ug/mL for 20 min and measured 72 hr post compound treatment by half-leaf method2010Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5
Synthesis and antiviral activities of phenanthroindolizidine alkaloids and their derivatives.
AID1081314In vivo antiviral activity against Tobacco mosaic virus strain U1 (TMV) infected left side of Nicotiana glutinosa leaves assessed as decrease in local lesion numbers co-incubated with virus for 30 min before inoculation onto leaves measured at 3-4 days af2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Anti-tobacco mosaic virus (TMV) Quassinoids from Brucea javanica (L.) Merr.
AID1082876In vivo antiviral activity against Tobacco mosaic virus (TMV) inoculated left side of Nicotiana. tabacum L. leaves assessed as inactivation effect at 100 ug/mL co-incubated with virus measured after 3 to 4 days2012Journal of agricultural and food chemistry, Jun-13, Volume: 60, Issue:23
Design, synthesis, antiviral activity, and SARs of 14-aminophenanthroindolizidines.
AID1112991Antiviral activity against Tobacco mosaic virus (TMV) in tobacco plant leaf assessed as protection effect at 100 ug/ml after 3 to 4 days2013Journal of agricultural and food chemistry, Feb-06, Volume: 61, Issue:5
Synthesis and antiviral activities of antofine analogues with different C-6 substituent groups.
AID1080736Antiviral activity against Tobacco mosaic virus U1 (TMV) infected Nicotiana tabacum cv. K326 leaves assessed as inhibition of viral replication measured 48 hr after compound exposure by leaf-disk method2009Journal of agricultural and food chemistry, Aug-12, Volume: 57, Issue:15
Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioides Benn.
AID1080341Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 500 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Feb-13, Volume: 56, Issue:3
Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety.
AID1081048Antiviral activity against Tobacco mosaic virus (TMV) inoculated on whole Nicotiana tabacum leaves followed by smearing with 500 ug/mL compound solution on left side of leaves assessed as viral infection curative effect measured 3 to 4 days post viral inf2010Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5
Synthesis and antiviral activities of phenanthroindolizidine alkaloids and their derivatives.
AID1228085Antiviral activity against TMV U1 infected on 20 mins compound treated fresh leaves from 5 to 6 growth stage Nicotiana glutinosa assessed as inhibition of virus growth at 50 ug/ml cultured at 25 degC for 72 hrs by half-leaf method2015Journal of natural products, Apr-24, Volume: 78, Issue:4
Bioactive Limonoid Constituents of Munronia henryi.
AID390531Increase in PR-5 gene expression in TMV-infected tobacco leaf assessed as gene expression ratio on day 5 by RT-PCR2008Bioorganic & medicinal chemistry, Nov-15, Volume: 16, Issue:22
Synthesis and antiviral activity of novel pyrazole derivatives containing oxime esters group.
AID1081047Antiviral activity against Tobacco mosaic virus (TMV) inoculated on fresh tobacco leaves followed by dipping into compound solution at 500 ug/mL for 20 min and measured 72 hr post compound treatment by half-leaf method2010Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5
Synthesis and antiviral activities of phenanthroindolizidine alkaloids and their derivatives.
AID1081315In vivo antiviral activity against Tobacco mosaic virus strain U1 (TMV) infected left side of Nicotiana glutinosa leaves assessed as decrease in local lesion numbers at 10 uM co-incubated with virus for 30 min before inoculation onto leaves measured at 3-2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Anti-tobacco mosaic virus (TMV) Quassinoids from Brucea javanica (L.) Merr.
AID1080364Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 62.5 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and antiviral activities of cyanoacrylate derivatives containing an alpha-aminophosphonate moiety.
AID322717Antiviral activity against TMV-infected tobacco leaves assessed as protection against viral infection at 500 mg/L2008Bioorganic & medicinal chemistry, Mar-15, Volume: 16, Issue:6
Synthesis and antiviral activities of novel chiral cyanoacrylate derivatives with (E) configuration.
AID322719Antiviral activity against TMV-infected tobacco leaves assessed as curative effect against viral disease at 500 mg/L2008Bioorganic & medicinal chemistry, Mar-15, Volume: 16, Issue:6
Synthesis and antiviral activities of novel chiral cyanoacrylate derivatives with (E) configuration.
AID1080366Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 250 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and antiviral activities of cyanoacrylate derivatives containing an alpha-aminophosphonate moiety.
AID1092193In vivo antiviral activity against Tobacco mosaic virus (TMV) inoculated right side of Nicotiana tabacum L. leaves assessed as protection effect at 100 ug/mL preincubated 12 hr before viral challenge measured after 3 to 4 days2012Journal of agricultural and food chemistry, Oct-17, Volume: 60, Issue:41
Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of phenanthroindolizidines and their analogues.
AID1082835Inhibition of Tobacco mosaic virus (TMV) infection in Nicotiana glutinosa after 3 to 4 days by half-leaf method2012Journal of agricultural and food chemistry, May-02, Volume: 60, Issue:17
The limonoids and their antitobacco mosaic virus (TMV) activities from Munronia unifoliolata Oliv.
AID1081056Antiviral activity against Tobacco mosaic virus (TMV) inoculated on fresh tobacco leaves followed by dipping into compound solution at 25 ug/mL for 20 min and measured 72 hr post compound treatment by half-leaf method2010Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5
Synthesis and antiviral activities of phenanthroindolizidine alkaloids and their derivatives.
AID1080415In vivo antiviral activity against Tobacco mosaic virus (TMV) infected left side of tobacco leaves assessed as inactivation effect co-incubated with virus for 30 min before inoculation onto leaves measured at 3-4 days after viral challenge2008Journal of agricultural and food chemistry, Nov-12, Volume: 56, Issue:21
Synthesis and antiviral activities of pyrazole derivatives containing an oxime moiety.
AID732661Antiviral activity against TMV strain U1 infected in Nicotiana glutinosa leaves assessed as decrease in number of local leaf lesions incubated with virus for 30 mins prior to inoculation on leaves measured 3 to 4 days post-viral infection by half-leaf met2013Journal of natural products, Feb-22, Volume: 76, Issue:2
Antiviral phenolic compounds from Arundina gramnifolia.
AID1081812Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 100 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2010Journal of agricultural and food chemistry, Dec-08, Volume: 58, Issue:23
Design, synthesis, and antiviral evaluation of phenanthrene-based tylophorine derivatives as potential antiviral agents.
AID1080573Antiviral activity against Tobacco mosaic virus (TMV) in compound treated Nicotiana tabacum L.leaves assessed as curative effect at 125 ug/ml2009Journal of agricultural and food chemistry, Feb-25, Volume: 57, Issue:4
Synthesis and antiviral activities of chiral thiourea derivatives containing an alpha-aminophosphonate moiety.
AID1080739Antiviral activity against Tobacco mosaic virus U1 (TMV) infected Nicotiana tabacum cv. K326 leaves assessed as inhibition of viral replication at 50 ug/mL in presence of 25 ug/mL quassinoid nigakilactone B measured 48 hr after compound exposure by leaf-d2009Journal of agricultural and food chemistry, Aug-12, Volume: 57, Issue:15
Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioides Benn.
AID1080342Antiviral activity against Tobacco mosaic virus (TMV) inoculated on 500 ug/mL compound smeared Nicotiana tabacum leaves assessed as protective effect against viral infection measured 3 to 4 days post viral infection2008Journal of agricultural and food chemistry, Feb-13, Volume: 56, Issue:3
Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety.
AID1082872In vivo antiviral activity against Tobacco mosaic virus (TMV) inoculated right side of Nicotiana. tabacum L. leaves assessed as protection effect at 100 ug/mL preincubated 12 hr before viral challenge measured after 3 to 4 days2012Journal of agricultural and food chemistry, Jun-13, Volume: 60, Issue:23
Design, synthesis, antiviral activity, and SARs of 14-aminophenanthroindolizidines.
AID1228090Antiviral activity against 30 mins compound pre-treated TMV U1 infected on Nicotiana glutinosa leaves assessed as virus inactivation effect by measuring local lesion numbers after 3 to 4 days post virus inoculation at 40 ug/ml by half-leaf method relative2015Journal of natural products, Apr-24, Volume: 78, Issue:4
Bioactive Limonoid Constituents of Munronia henryi.
AID1112989Antiviral activity against Tobacco mosaic virus (TMV) in tobacco plant leaf assessed as inactivation effect at 500 ug/ml after 3 to 4 days2013Journal of agricultural and food chemistry, Feb-06, Volume: 61, Issue:5
Synthesis and antiviral activities of antofine analogues with different C-6 substituent groups.
AID1080572Antiviral activity against Tobacco mosaic virus (TMV) in compound treated Nicotiana tabacum L.leaves assessed as curative effect at 250 ug/ml2009Journal of agricultural and food chemistry, Feb-25, Volume: 57, Issue:4
Synthesis and antiviral activities of chiral thiourea derivatives containing an alpha-aminophosphonate moiety.
AID696756Antiviral activity against Tobacco mosaic virus infected in right side leaf of Nicotiana glutinosa at 80 uM after 3 to 4 days by half-leaf method2012Journal of natural products, Nov-26, Volume: 75, Issue:11
Antiviral chromones from the stem of Cassia siamea.
AID1081050Antiviral activity against Tobacco mosaic virus (TMV) pre-treated with 500 ug/mL compound for 30 min followed by inoculation on left side of Nicotiana tabacum leaves assessed as virus inactivation effect measured 3 to 4 days post viral infection2010Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5
Synthesis and antiviral activities of phenanthroindolizidine alkaloids and their derivatives.
AID732662Antiviral activity against TMV strain U1 infected in Nicotiana glutinosa leaves assessed as decrease in number of local leaf lesions at 20 uM incubated with virus for 30 mins prior to inoculation on leaves measured 3 to 4 days post-viral infection by half2013Journal of natural products, Feb-22, Volume: 76, Issue:2
Antiviral phenolic compounds from Arundina gramnifolia.
AID1592373Antiviral activity against Tobacco mosaic virus inoculated in Nicotiana tabacum leaves assessed as passivation by measuring local lesion numbers at 100 mg/l pre-incubated with virus for 30 mins followed by inoculation and measured up to 4 days2019European journal of medicinal chemistry, Apr-01, Volume: 167Chemical synthesis, crystal structure, versatile evaluation of their biological activities and molecular simulations of novel pyrithiobac derivatives.
AID1592372Antiviral activity against Tobacco mosaic virus inoculated in Nicotiana tabacum leaves assessed as passivation by measuring local lesion numbers at 500 mg/l pre-incubated with virus for 30 mins followed by inoculation and measured up to 4 days2019European journal of medicinal chemistry, Apr-01, Volume: 167Chemical synthesis, crystal structure, versatile evaluation of their biological activities and molecular simulations of novel pyrithiobac derivatives.
AID1082875In vivo antiviral activity against Tobacco mosaic virus (TMV) pre-inoculated Nicotiana. tabacum L. leaves assessed as curative effect at 500 ug/mL measured after 3 to 4 days2012Journal of agricultural and food chemistry, Jun-13, Volume: 60, Issue:23
Design, synthesis, antiviral activity, and SARs of 14-aminophenanthroindolizidines.
AID1080576Antiviral activity against Tobacco mosaic virus (TMV) in compound treated Nicotiana tabacum L.leaves assessed as protective effect from local lesions at 500 ug/ml measured after 3 to 4 days2009Journal of agricultural and food chemistry, Feb-25, Volume: 57, Issue:4
Synthesis and antiviral activities of chiral thiourea derivatives containing an alpha-aminophosphonate moiety.
AID1082833Inhibition of Tobacco mosaic virus (TMV) infection in Nicotiana glutinosa assessed as infection inhibition rate at 10 ug/ml after 3 to 4 days by half-leaf method2012Journal of agricultural and food chemistry, May-02, Volume: 60, Issue:17
The limonoids and their antitobacco mosaic virus (TMV) activities from Munronia unifoliolata Oliv.
AID1080417In vivo antiviral activity against Tobacco mosaic virus (TMV) infected left side of tobacco leaves assessed as inactivation effect at 31.8 ug/ml co-incubated with virus for 30 min before inoculation onto leaves measured at 3-4 days after viral challenge2008Journal of agricultural and food chemistry, Nov-12, Volume: 56, Issue:21
Synthesis and antiviral activities of pyrazole derivatives containing an oxime moiety.
AID1080340Antiviral activity against Tobacco mosaic virus (TMV) inoculated on whole Nicotiana tabacum leaves followed by smearing with 500 ug/mL compound solution on left side of leaves assessed as viral infection curative effect measured 3 to 4 days post viral inf2008Journal of agricultural and food chemistry, Feb-13, Volume: 56, Issue:3
Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety.
AID1228088Antiviral activity against TMV U1 infected on Nicotiana glutinosa leaves smeared with virus before compound treatment assessed as virus infection curative effect by measuring local lesion numbers after 3 to 4 days post virus inoculation at 200 ug/ml by ha2015Journal of natural products, Apr-24, Volume: 78, Issue:4
Bioactive Limonoid Constituents of Munronia henryi.
AID1228095Antiviral activity against 30 mins compound pre-treated TMV U1 infected on Nicotiana glutinosa leaves assessed as virus inactivation effect by measuring local lesion numbers after 3 to 4 days post virus inoculation by half-leaf method relative to untreate2015Journal of natural products, Apr-24, Volume: 78, Issue:4
Bioactive Limonoid Constituents of Munronia henryi.
AID1080737Antiviral activity against Tobacco mosaic virus U1 (TMV) infected Nicotiana glutinosa leaves assessed as inhibition of viral infection at 50 ug/mL using compound pre-treated virus suspension measured 5 to 6 days after compound exposure2009Journal of agricultural and food chemistry, Aug-12, Volume: 57, Issue:15
Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioides Benn.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (39)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (20.51)29.6817
2010's25 (64.10)24.3611
2020's6 (15.38)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 22.96

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index22.96 (24.57)
Research Supply Index3.69 (2.92)
Research Growth Index4.76 (4.65)
Search Engine Demand Index47.56 (26.88)
Search Engine Supply Index4.00 (0.95)

This Compound (22.96)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (2.56%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other38 (97.44%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
benzoic acid
Benzoic Acid: A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.. benzoic acid : A compound comprising a benzene ring core carrying a carboxylic acid substituent.. aromatic carboxylic acid : Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring.		2.0410benzoic acidsalgal metabolite;
antimicrobial food preservative;
drug allergen;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
human xenobiotic metabolite;
plant metabolite
salicylic acid
Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).		2.1710monohydroxybenzoic acidalgal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite
cytosine
[no description available]		3.2110aminopyrimidine;
pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
inositol
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.. inositol : Any cyclohexane-1,2,3,4,5,6-hexol.. 1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.. muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.		2.2510cyclitol;
hexol
fluorouracil
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.. 5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.		2.0210nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
cytidine
[no description available]		5.55190cytidinesEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
oxazoles
Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.. 1,3-oxazole : A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3.. oxazole : An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom.		2.21101,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
tetrachloroisophthalonitrile
tetrachloroisophthalonitrile: structure. chlorothalonil : A dinitrile that is benzene-1,3-dicarbonitrile substituted by four chloro groups. A non-systemic fungicide first introduced in the 1960s, it is used to control a range of diseases in a wide variety of crops.		2.2110aromatic fungicide;
dinitrile;
tetrachlorobenzene		antifungal agrochemical
amicetin
[no description available]		3.2110
dioxohexahydrotriazine
[no description available]		2.4820
zidovudine
Zidovudine: A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.. zidovudine : A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.		2.4820azide;
pyrimidine 2',3'-dideoxyribonucleoside		antimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor
paclitaxel
Taxus: Genus of coniferous yew trees or shrubs, several species of which have medicinal uses. Notable is the Pacific yew, Taxus brevifolia, which is used to make the anti-neoplastic drug taxol (PACLITAXEL).		2.5320taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
ribavirin
Rebetron: Rebetron is tradename		3.03401-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide		anticoronaviral agent;
antiinfective agent;
antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
lentinan
[no description available]		7.4110
kasugamycin
kasugamycin: experimental antimicrobial agent from Streptomyces kausugaensis; used in pseudomonas infections; interfers with protein synthesis in susceptible Escherichia coli. kasugamycin : An amino cyclitol glycoside that is isolated from Streptomyces kasugaensis and exhibits antibiotic and fungicidal properties.		7.2510
1,7-phenanthroline
[no description available]		2.1310phenanthroline
tylophorine
tylophorine: phenanthroindolizidine alkaloid		2.4720organic heteropentacyclic compound;
organonitrogen heterocyclic compound
pimprinine
pimprinine: structure		2.2110
1,3,4-oxadiazole
1,3,4-oxadiazole: structure in first source		2.1110
bruceine d
bruceine D: from fructus of Brucea javanica (Chinese name Yadanzi). bruceine D : A quassinoid that is 13,20-epoxypicras-3-ene substituted by hydroxy groups at positions 1, 11, 12, 14 and 15 and oxo groups at positions 2 and 16. Isolated from the ethanol extract of the stem of Brucea mollis, it exhibits cytotoxic activity.		2.0510
gougerotin
[no description available]		3.2110
bruceine b
bruceine B: quassinoid which inhibits protein synthesis & DNA synthesis in cells; structure in first source		2.0510triterpenoid
organophosphonates
hydrogenphosphite : A divalent inorganic anion resulting from the removal of a proton from two of the hydroxy groups of phosphorous acid.		2.4620divalent inorganic anion;
phosphite ion
moracin m
moracin M: has been isolated from Morus alba L.; structure in first source		2.0810benzofurans
5-methoxycanthin-6-one
5-methoxycanthin-6-one: isolated from Zanthoxylum chiloperone; structure in first source		2.0510alkaloid;
organic heterotetracyclic compound
dcb 3503
[no description available]		2.0710
validamycin a
validamycin A : A member of the class of validamycins that is (1R,2S,3S,4S,6R)-4-amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol in which the hydroxy group at position 1 has been converted to its beta-D-glucoside and in which one of the hydrogens attached to the nitrogen is replaced by a (1R,4R,5R,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl group. It is the major validamycin produced by Streptomyces hygroscopicus.		7.2510antibiotic fungicide;
polyol;
secondary amino compound;
validamycins		antifungal agrochemical;
EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitor;
EC 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitor;
EC 3.2.1.28 (alpha,alpha-trehalase) inhibitor
e-z cinnamic acid
cinnamic acid : A monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. It is found in Cinnamomum cassia.. trans-cinnamic acid : The E (trans) isomer of cinnamic acid		2.0410cinnamic acidplant metabolite
oleic acid
Oleic Acid: An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed). oleic acid : An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.		2.1510octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent
Methyl nigakinone
4,5-dimethoxycanthin-6-one: an active metabolite of Picrasma quassiodes; structure in first source		2.0510beta-carbolines
antofine
antofine: structure in first source. (-)-antofine : An organic heteropentacyclic compound that is (13aR)-9,11,12,13,13a,14-hexahydrodibenzo[f,h]pyrrolo[1,2-b]isoquinoline substituted at positions 2, 3 and 6 by methoxy groups. It is an alkaloid produced by relatives of the milkweed family and exhibits antiviral, anti-inflammatory, antiadipogenic and antitumorigenic activities.		3.1750alkaloid antibiotic;
alkaloid;
aromatic ether;
organic heteropentacyclic compound		angiogenesis inhibitor;
anti-inflammatory agent;
antimicrobial agent;
antineoplastic agent;
antiviral agent;
phytotoxin;
plant metabolite
thiourea
Thiourea: A photographic fixative used also in the manufacture of resins. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance may reasonably be anticipated to be a carcinogen (Merck Index, 9th ed). Many of its derivatives are ANTITHYROID AGENTS and/or FREE RADICAL SCAVENGERS.. thiourea : The simplest member of the thiourea class, consisting of urea with the oxygen atom substituted by sulfur.		2.0610one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore
n,n'-methylene-bis(2-amino-5-sulfhydryl-1,3,4-thiadiazole)
bismerthiazol: a bactericide and fungicide		2.2510
barakol
barakol: a tricyclic 3a,4-dihydro-3a,8-dihydroxy-2,5-dimethyl-1,4-dioxaphenalene ring system		2.0710
1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethoxyphenoxysulfonyl)urea
1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethoxyphenoxysulfonyl)urea: herbicide; structure in first source		2.2110aromatic ether
tylophorine b
tylophorine B: isolated from Albizzia julibrissin; structure in first source		2.0510
nikkomycin
[no description available]		3.2110
mildiomycin
mildiomycin: antibiotic nucleoside produced by Streptoverticillium rimofaciens effective against powdery mildew; 5-hydroxymethyl cytosine found on acid hydrolysis; RN given refers to (S)-isomer		3.2110
mocetinostat
mocetinostat: undergoing phase II clinical trials for treatment of cancer. mocetinostat : A benzamide obtained by formal condensation of the carboxy group of 4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an orally active and isotype-selective HDAC inhibitor which exhibits antitumour activity (IC50 = 0.15, 0.29, 1.66 and 0.59 muM for HDAC1, HDAC2, HDAC3 and HDAC11).		2.830aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
oxadiazoles
Oxadiazoles: Compounds containing five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom which exist in various regioisomeric forms.		2.1110
chlorantranilipole
chlorantranilipole: anthranilic diamide insecticide.that disrupts mating in codling moth (Lepidoptera: Tortricidae). chlorantraniliprole : A carboxamide resulting from the formal condensation of the carboxylic acid group of 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid with the primary amino group of 2-amino-5-chloro-N,3-dimethylbenzamide. The first of the anthranilic diamide insecticides, it is a ryanodine receptor activator and is used to protect a wide variety of crops, including corn, cotton, grapes, rice and potatoes.		2.2110monochlorobenzenes;
organobromine compound;
pyrazole insecticide;
pyrazoles;
pyridines;
secondary carboxamide		ryanodine receptor agonist
chlorophyll a
Chlorophyll: Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.. chlorophyll : A family of magnesium porphyrins, defined by the presence of a fifth ring beyond the four pyrrole-like rings. The rings can have various side chains which usually include a long phytol chain.		2.0610chlorophyll;
methyl ester		cofactor
chitosan
[no description available]		7.4110
dufulin
dufulin: structure in first source		2.1310
blasticidin s
blasticidin S: RN given refers to (S)-isomer; structure. blasticidin S : A blasticidin that is an antibiotic obtained from Streptomyces griseochromogene.		3.2110
4-hydroxyquinazoline
4-oxo-3,4-dihydroquinazoline: structure in first source		2.110quinazolines
ConditionIndicatedRelationship StrengthStudiesTrials