An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of alpha,alpha-trehalase (EC 2.4.1.28).
ChEBI ID: 83762
| Member | Definition | Class | Studies | Trials |
|---|---|---|---|---|
| validamycin a | A member of the class of validamycins that is (1R,2S,3S,4S,6R)-4-amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol in which the hydroxy group at position 1 has been converted to its beta-D-glucoside and in which one of the hydrogens attached to the nitrogen is replaced by a (1R,4R,5R,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl group. It is the major validamycin produced by Streptomyces hygroscopicus. | validamycins; | 312 | 0 | |
| validamycin-A(1+) | An ammonium ion resulting from the protonation of the amino group of validamycin A. The major species at pH 7.3. | ammonium ion derivative | 0 | 0 |
| validoxylamine a | An amino cyclitol that is (1R,2S,3S,4S,6R)-4-amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol in which one of the hydrogens attached to the nitrogen is replaced by a (1R,4R,5R,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl group. | amino cyclitol; | 30 | 0 | |
| Studies | Pre-1990 | 1990's | 2000's | 2010's | Post-2020 |
|---|---|---|---|---|---|
| 88 | 5 | 8 | 23 | 44 | 8 |