Page last updated: 2024-11-08

6-n-tridecylsalicylic acid

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Description

6-n-tridecylsalicylic acid: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID161306
CHEMBL ID476921
CHEBI ID175101
SCHEMBL ID20298323
MeSH IDM0089268

Synonyms (34)

Synonym
CHEBI:175101
20261-38-5
benzoic acid, 2-hydroxy-6-tridecyl-
6-n-tridecylsalicylic acid
2-hydroxy-6-tridecylbenzoic acid
6-tridecylsalicylic acid
salicylic acid, 6-tridecyl-
brn 2660108
c20h32o3
bdbm50259931
CHEMBL476921 ,
6-tridecyl phenol
S9445
ginkgoneolic acid
ginkgolic acid c13:0
AKOS015888424
ginkgolic acid (c13:0)
CS-3726
HY-N0078
mfcd01661602
SCHEMBL20298323
FT-0697966
DTXSID10174105
ginkgolic acid c13:0, analytical standard
AS-62129
6-tridecyl-salicylic acid
2-hydroxy-6-tridecyl-benzoic acid
salicylic acid, 6-tridecyl- (8ci)
2-tridecyl-6-hydroxybenzoic acid
ginkgolic acid (13:0)
Q63395389
CCG-267712
ginkgolic acid (13:0);ginkgoneolic acid;6-tridecylsalicylic acid
ginkgolic acid (c130)
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
hydroxybenzoic acidAny benzoic acid carrying one or more phenolic hydroxy groups on the benzene ring.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (6)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)IC50 (µMol)16.27005.66005.66005.6600AID401415
BH3-interacting domain death agonistHomo sapiens (human)Ki0.20000.20004.20008.6000AID1635029
Bcl-2-like protein 1Homo sapiens (human)Ki0.20000.00000.45819.0000AID1635028
Induced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)Ki0.20000.00101.46539.5400AID1635029
Bcl-2 homologous antagonist/killerHomo sapiens (human)Ki0.20000.00102.71829.0000AID1635028
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (119)

Processvia Protein(s)Taxonomy
in utero embryonic development1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
epidermal growth factor receptor signaling pathway1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
phospholipid catabolic process1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
positive regulation of epithelial cell migration1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
cellular response to vascular endothelial growth factor stimulus1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
phosphatidylinositol metabolic process1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
cellular response to epidermal growth factor stimulus1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
release of cytochrome c from mitochondriaBH3-interacting domain death agonistHomo sapiens (human)
protein targeting to mitochondrionBH3-interacting domain death agonistHomo sapiens (human)
extrinsic apoptotic signaling pathway via death domain receptorsBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of mitochondrial membrane potentialBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of protein-containing complex assemblyBH3-interacting domain death agonistHomo sapiens (human)
regulation of T cell proliferationBH3-interacting domain death agonistHomo sapiens (human)
signal transduction in response to DNA damageBH3-interacting domain death agonistHomo sapiens (human)
mitochondrial ATP synthesis coupled electron transportBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of apoptotic processBH3-interacting domain death agonistHomo sapiens (human)
regulation of epithelial cell proliferationBH3-interacting domain death agonistHomo sapiens (human)
neuron apoptotic processBH3-interacting domain death agonistHomo sapiens (human)
protein-containing complex assemblyBH3-interacting domain death agonistHomo sapiens (human)
establishment of protein localization to membraneBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of release of cytochrome c from mitochondriaBH3-interacting domain death agonistHomo sapiens (human)
hepatocyte apoptotic processBH3-interacting domain death agonistHomo sapiens (human)
mitochondrial outer membrane permeabilizationBH3-interacting domain death agonistHomo sapiens (human)
supramolecular fiber organizationBH3-interacting domain death agonistHomo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damageBH3-interacting domain death agonistHomo sapiens (human)
regulation of G1/S transition of mitotic cell cycleBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of fibroblast apoptotic processBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathwayBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathwayBH3-interacting domain death agonistHomo sapiens (human)
apoptotic mitochondrial changesBH3-interacting domain death agonistHomo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic processBH3-interacting domain death agonistHomo sapiens (human)
response to cytokineBcl-2-like protein 1Homo sapiens (human)
negative regulation of apoptotic processBcl-2-like protein 1Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsBcl-2-like protein 1Homo sapiens (human)
ovarian follicle developmentBcl-2-like protein 1Homo sapiens (human)
in utero embryonic developmentBcl-2-like protein 1Homo sapiens (human)
release of cytochrome c from mitochondriaBcl-2-like protein 1Homo sapiens (human)
endocytosisBcl-2-like protein 1Homo sapiens (human)
germ cell developmentBcl-2-like protein 1Homo sapiens (human)
spermatogenesisBcl-2-like protein 1Homo sapiens (human)
male gonad developmentBcl-2-like protein 1Homo sapiens (human)
apoptotic mitochondrial changesBcl-2-like protein 1Homo sapiens (human)
fertilizationBcl-2-like protein 1Homo sapiens (human)
regulation of cytokinesisBcl-2-like protein 1Homo sapiens (human)
positive regulation of mononuclear cell proliferationBcl-2-like protein 1Homo sapiens (human)
ectopic germ cell programmed cell deathBcl-2-like protein 1Homo sapiens (human)
regulation of growthBcl-2-like protein 1Homo sapiens (human)
negative regulation of apoptotic processBcl-2-like protein 1Homo sapiens (human)
negative regulation of neuron apoptotic processBcl-2-like protein 1Homo sapiens (human)
dendritic cell proliferationBcl-2-like protein 1Homo sapiens (human)
response to cycloheximideBcl-2-like protein 1Homo sapiens (human)
regulation of mitochondrial membrane permeabilityBcl-2-like protein 1Homo sapiens (human)
epithelial cell proliferationBcl-2-like protein 1Homo sapiens (human)
negative regulation of developmental processBcl-2-like protein 1Homo sapiens (human)
neuron apoptotic processBcl-2-like protein 1Homo sapiens (human)
defense response to virusBcl-2-like protein 1Homo sapiens (human)
regulation of mitochondrial membrane potentialBcl-2-like protein 1Homo sapiens (human)
cellular response to amino acid stimulusBcl-2-like protein 1Homo sapiens (human)
cellular response to alkaloidBcl-2-like protein 1Homo sapiens (human)
cellular response to gamma radiationBcl-2-like protein 1Homo sapiens (human)
apoptotic process in bone marrow cellBcl-2-like protein 1Homo sapiens (human)
negative regulation of release of cytochrome c from mitochondriaBcl-2-like protein 1Homo sapiens (human)
dendritic cell apoptotic processBcl-2-like protein 1Homo sapiens (human)
hepatocyte apoptotic processBcl-2-like protein 1Homo sapiens (human)
negative regulation of execution phase of apoptosisBcl-2-like protein 1Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damageBcl-2-like protein 1Homo sapiens (human)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathwayBcl-2-like protein 1Homo sapiens (human)
negative regulation of protein localization to plasma membraneBcl-2-like protein 1Homo sapiens (human)
negative regulation of reproductive processBcl-2-like protein 1Homo sapiens (human)
negative regulation of dendritic cell apoptotic processBcl-2-like protein 1Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandBcl-2-like protein 1Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathwayBcl-2-like protein 1Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damageBcl-2-like protein 1Homo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligandBcl-2-like protein 1Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic processBcl-2-like protein 1Homo sapiens (human)
DNA damage responseInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
response to cytokineInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
cell fate determinationInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
negative regulation of autophagyInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
cellular homeostasisInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
positive regulation of apoptotic processInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
negative regulation of apoptotic processInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
protein transmembrane transportInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligandInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathwayInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
negative regulation of anoikisInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic processInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
mitochondrial fusionInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
release of cytochrome c from mitochondriaInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damageInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
B cell homeostasisBcl-2 homologous antagonist/killerHomo sapiens (human)
B cell apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
release of cytochrome c from mitochondriaBcl-2 homologous antagonist/killerHomo sapiens (human)
blood vessel remodelingBcl-2 homologous antagonist/killerHomo sapiens (human)
myeloid cell homeostasisBcl-2 homologous antagonist/killerHomo sapiens (human)
B cell negative selectionBcl-2 homologous antagonist/killerHomo sapiens (human)
apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
mitochondrial fusionBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of cell population proliferationBcl-2 homologous antagonist/killerHomo sapiens (human)
response to xenobiotic stimulusBcl-2 homologous antagonist/killerHomo sapiens (human)
response to fungusBcl-2 homologous antagonist/killerHomo sapiens (human)
response to mycotoxinBcl-2 homologous antagonist/killerHomo sapiens (human)
response to UV-CBcl-2 homologous antagonist/killerHomo sapiens (human)
establishment or maintenance of transmembrane electrochemical gradientBcl-2 homologous antagonist/killerHomo sapiens (human)
response to gamma radiationBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of calcium ion transport into cytosolBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of gene expressionBcl-2 homologous antagonist/killerHomo sapiens (human)
response to organic cyclic compoundBcl-2 homologous antagonist/killerHomo sapiens (human)
endocrine pancreas developmentBcl-2 homologous antagonist/killerHomo sapiens (human)
animal organ regenerationBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of protein-containing complex assemblyBcl-2 homologous antagonist/killerHomo sapiens (human)
endoplasmic reticulum calcium ion homeostasisBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of endoplasmic reticulum calcium ion concentrationBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of peptidyl-serine phosphorylationBcl-2 homologous antagonist/killerHomo sapiens (human)
cellular response to unfolded proteinBcl-2 homologous antagonist/killerHomo sapiens (human)
cellular response to UVBcl-2 homologous antagonist/killerHomo sapiens (human)
limb morphogenesisBcl-2 homologous antagonist/killerHomo sapiens (human)
response to hydrogen peroxideBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
fibroblast apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
response to ethanolBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of proteolysisBcl-2 homologous antagonist/killerHomo sapiens (human)
regulation of mitochondrial membrane permeabilityBcl-2 homologous antagonist/killerHomo sapiens (human)
post-embryonic camera-type eye morphogenesisBcl-2 homologous antagonist/killerHomo sapiens (human)
epithelial cell proliferationBcl-2 homologous antagonist/killerHomo sapiens (human)
establishment of localization in cellBcl-2 homologous antagonist/killerHomo sapiens (human)
regulation of cell cycleBcl-2 homologous antagonist/killerHomo sapiens (human)
regulation of mitochondrial membrane potentialBcl-2 homologous antagonist/killerHomo sapiens (human)
vagina developmentBcl-2 homologous antagonist/killerHomo sapiens (human)
calcium ion transport into cytosolBcl-2 homologous antagonist/killerHomo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressBcl-2 homologous antagonist/killerHomo sapiens (human)
thymocyte apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
cellular response to mechanical stimulusBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of release of cytochrome c from mitochondriaBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of release of cytochrome c from mitochondriaBcl-2 homologous antagonist/killerHomo sapiens (human)
apoptotic signaling pathwayBcl-2 homologous antagonist/killerHomo sapiens (human)
intrinsic apoptotic signaling pathwayBcl-2 homologous antagonist/killerHomo sapiens (human)
activation of cysteine-type endopeptidase activityBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of endoplasmic reticulum unfolded protein responseBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayBcl-2 homologous antagonist/killerHomo sapiens (human)
apoptotic process involved in blood vessel morphogenesisBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of IRE1-mediated unfolded protein responseBcl-2 homologous antagonist/killerHomo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligandBcl-2 homologous antagonist/killerHomo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damageBcl-2 homologous antagonist/killerHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (22)

Processvia Protein(s)Taxonomy
phosphatidylinositol phospholipase C activity1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
guanyl-nucleotide exchange factor activity1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
calcium ion binding1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
protein binding1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
calcium-dependent phospholipase C activity1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
death receptor bindingBH3-interacting domain death agonistHomo sapiens (human)
protein bindingBH3-interacting domain death agonistHomo sapiens (human)
ubiquitin protein ligase bindingBH3-interacting domain death agonistHomo sapiens (human)
protein bindingBcl-2-like protein 1Homo sapiens (human)
protein kinase bindingBcl-2-like protein 1Homo sapiens (human)
identical protein bindingBcl-2-like protein 1Homo sapiens (human)
BH3 domain bindingBcl-2-like protein 1Homo sapiens (human)
BH domain bindingBcl-2-like protein 1Homo sapiens (human)
protein bindingInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
protein transmembrane transporter activityInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
protein heterodimerization activityInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
BH3 domain bindingInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
channel activityInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
BH domain bindingInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
molecular_functionBcl-2 homologous antagonist/killerHomo sapiens (human)
protein bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
porin activityBcl-2 homologous antagonist/killerHomo sapiens (human)
heat shock protein bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
identical protein bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
protein homodimerization activityBcl-2 homologous antagonist/killerHomo sapiens (human)
transmembrane transporter bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
protein-containing complex bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
metal ion bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
protein heterodimerization activityBcl-2 homologous antagonist/killerHomo sapiens (human)
protein-folding chaperone bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
BH domain bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (20)

Processvia Protein(s)Taxonomy
plasma membrane1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
ruffle1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
cytoplasm1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
lamellipodium1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
COP9 signalosome1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1Bos taurus (cattle)
mitochondrial outer membraneBH3-interacting domain death agonistHomo sapiens (human)
cytosolBH3-interacting domain death agonistHomo sapiens (human)
membraneBH3-interacting domain death agonistHomo sapiens (human)
mitochondrionBH3-interacting domain death agonistHomo sapiens (human)
cytosolBH3-interacting domain death agonistHomo sapiens (human)
cytoplasmBcl-2-like protein 1Homo sapiens (human)
mitochondrionBcl-2-like protein 1Homo sapiens (human)
mitochondrial outer membraneBcl-2-like protein 1Homo sapiens (human)
mitochondrial inner membraneBcl-2-like protein 1Homo sapiens (human)
mitochondrial matrixBcl-2-like protein 1Homo sapiens (human)
endoplasmic reticulumBcl-2-like protein 1Homo sapiens (human)
centrosomeBcl-2-like protein 1Homo sapiens (human)
cytosolBcl-2-like protein 1Homo sapiens (human)
synaptic vesicle membraneBcl-2-like protein 1Homo sapiens (human)
nuclear membraneBcl-2-like protein 1Homo sapiens (human)
Bcl-2 family protein complexBcl-2-like protein 1Homo sapiens (human)
mitochondrial outer membraneBcl-2-like protein 1Homo sapiens (human)
nucleusInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
nucleoplasmInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
cytoplasmInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
mitochondrionInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
mitochondrial outer membraneInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
cytosolInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
membraneInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
Bcl-2 family protein complexInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
mitochondrial outer membraneInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
mitochondrial outer membraneBcl-2 homologous antagonist/killerHomo sapiens (human)
mitochondrionBcl-2 homologous antagonist/killerHomo sapiens (human)
mitochondrial outer membraneBcl-2 homologous antagonist/killerHomo sapiens (human)
endoplasmic reticulumBcl-2 homologous antagonist/killerHomo sapiens (human)
cytosolBcl-2 homologous antagonist/killerHomo sapiens (human)
Bcl-2 family protein complexBcl-2 homologous antagonist/killerHomo sapiens (human)
BAK complexBcl-2 homologous antagonist/killerHomo sapiens (human)
pore complexBcl-2 homologous antagonist/killerHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (30)

Assay IDTitleYearJournalArticle
AID1802654Fluorescence Polarization Assay from Article 10.1016/j.chembiol.2017.01.003: \\Small-Molecule Inhibitors of the SOX18 Transcription Factor.\\2017Cell chemical biology, Mar-16, Volume: 24, Issue:3
Small-Molecule Inhibitors of the SOX18 Transcription Factor.
AID401423Growth inhibition of human CCD-18Co cells after 2 days by SRB assay1998Journal of natural products, Jul, Volume: 61, Issue:7
Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba.
AID1635030Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 72 hrs by resazurin dye based fluorescence assay2016Journal of natural products, Apr-22, Volume: 79, Issue:4
Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.
AID1635035Binding affinity to Mcl-1 (unknown origin) assessed as effect on protein HN resonances at 1.5 equivalent by HSQC 1H-15N NMR spectroscopy2016Journal of natural products, Apr-22, Volume: 79, Issue:4
Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.
AID1082436Inhibition of fruit-infesting behavior of Cydia pomonella (codling moth) neonates infested in apple fruit plugs assessed as feeding deterrence index at 1 mg/mL2011Journal of agricultural and food chemistry, Oct-26, Volume: 59, Issue:20
Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
AID1635034Binding affinity to Bcl-XL (unknown origin) assessed as effect on protein HN resonances at 1.5 equivalent by HSQC 1H-15N NMR spectroscopy2016Journal of natural products, Apr-22, Volume: 79, Issue:4
Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.
AID1635031Binding affinity to Bid (unknown origin) assessed as micelles formation at 0.25 to 5 equivalent by 1H NMR spectra analysis2016Journal of natural products, Apr-22, Volume: 79, Issue:4
Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.
AID401419Growth inhibition of human MCF7 cells after 2 days by SRB assay1998Journal of natural products, Jul, Volume: 61, Issue:7
Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba.
AID1725879Inhibition of SUMO1 (unknown origin) assessed as reduction in SUMOylated RanGAP1 level at 50 uM incubated for 60 mins by western blot analysis2020ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors.
AID1725877Induction of autophagy-mediated apoptosis in human PC3 cells assessed as increase in cleave PARP level at 20 uM measured after 24 hrs by western blot analysis2020ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors.
AID1725883Cytotoxicity against human PC3 cells assessed as cell death at 5 to 10 uM incubated for 24 hrs by crystal violet staining based spectrophotometric analysis2020ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors.
AID1082427Inhibition of fruit-infesting behavior of Cydia pomonella (codling moth) neonates infested in apple fruit plugs assessed as feeding deterrence index at 0.5 mg/mL2011Journal of agricultural and food chemistry, Oct-26, Volume: 59, Issue:20
Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
AID1725884Cytotoxicity against human MDA-MB-231 cells assessed as cell death at 10 to 20 uM incubated for 24 hrs by crystal violet staining based spectrophotometric analysis2020ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors.
AID401421Growth inhibition of human SKOV3 cells after 2 days by SRB assay1998Journal of natural products, Jul, Volume: 61, Issue:7
Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba.
AID401420Growth inhibition of human HCT15 cells after 2 days by SRB assay1998Journal of natural products, Jul, Volume: 61, Issue:7
Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba.
AID1725880Inhibition of SUMO1 in human PC3 cells assessed as reduction in SUMOylation level at 10 to 20 uM measured after 24 hrs by western blot analysis2020ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors.
AID1082437Inhibition of fruit-infesting behavior of Cydia pomonella (codling moth) neonates infested in apple fruit plugs assessed as feeding deterrence index at 10 mg/mL2011Journal of agricultural and food chemistry, Oct-26, Volume: 59, Issue:20
Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
AID1725876Induction of autophagy-mediated apoptosis in human PC3 cells assessed as increase in cleave PARP level at 10 uM measured after 24 hrs by western blot analysis2020ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors.
AID1635028Inhibition of His-tagged Bcl-xL/5-carboxyfluorescein-Bak (unknown origin) after 1 hr by fluorescence polarization assay2016Journal of natural products, Apr-22, Volume: 79, Issue:4
Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.
AID1725881Inhibition of SUMO1 in human MDA-MB-231 cells assessed as reduction in SUMOylation level at 10 uM measured after 24 hrs by western blot analysis2020ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors.
AID1725888Inhibition of SUMO2 in human PC3 cells assessed as reduction in SUMOylation level at 10 uM measured after 24 hrs by western blot analysis2020ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors.
AID1635033Binding affinity to Bid (unknown origin) assessed as induction of chemical shift perturbations by NMR titration method2016Journal of natural products, Apr-22, Volume: 79, Issue:4
Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.
AID1725882Induction of autophagy in human PC3 cells assessed as increased of LC3-II level at 20 uM incubated for 24 hrs by Western blot analysis2020ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors.
AID1725878Induction of autophagy in human PC3 cells assessed as increased of LC3-II level at 10 uM incubated for 24 hrs by Western blot analysis2020ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors.
AID401418Growth inhibition of human A549 cells after 2 days by SRB assay1998Journal of natural products, Jul, Volume: 61, Issue:7
Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba.
AID401422Growth inhibition of human HT1197 cells after 2 days by SRB assay1998Journal of natural products, Jul, Volume: 61, Issue:7
Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba.
AID1635029Inhibition of His-tagged Mcl-1/5-carboxyfluorescein-Bid (unknown origin) after 1 hr by fluorescence polarization assay2016Journal of natural products, Apr-22, Volume: 79, Issue:4
Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.
AID1635032Binding affinity to Bid (unknown origin) at 2 equivalent assessed as interaction at Asp16/Ser17/Met18/Asp19 and Arg20 residues by 2D 1H-1H TOCSY analysis2016Journal of natural products, Apr-22, Volume: 79, Issue:4
Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.
AID1082429Inhibition of fruit-infesting behavior of Cydia pomonella (codling moth) neonates infested in apple fruit plugs assessed as feeding deterrence index at 5 mg/mL2011Journal of agricultural and food chemistry, Oct-26, Volume: 59, Issue:20
Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
AID401415Inhibition of bovine brain PI-PLCgamma11998Journal of natural products, Jul, Volume: 61, Issue:7
Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.38

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.38 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.38)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]