Compounds > meiogynin a
Page last updated: 2024-11-13

meiogynin a

Description

meiogynin A: from the bark of Meiogyne cylindrocarpa; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID42642427
CHEMBL ID556082
CHEMBL ID3339153
MeSH IDM0545696

Synonyms (4)

Synonym
meiogynin a
CHEMBL556082 ,
bdbm50295162
CHEMBL3339153
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (4)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
BH3-interacting domain death agonistHomo sapiens (human)Ki8.43330.20004.20008.6000AID1166894; AID1635029
Bcl-2-like protein 1Homo sapiens (human)Ki15.60000.00000.45819.0000AID1166893; AID1635028; AID421902
Induced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)Ki8.43330.00101.46539.5400AID1166894; AID1635029
Bcl-2 homologous antagonist/killerHomo sapiens (human)Ki17.20000.00102.71829.0000AID1166893; AID1635028
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (113)

Processvia Protein(s)Taxonomy
release of cytochrome c from mitochondriaBH3-interacting domain death agonistHomo sapiens (human)
protein targeting to mitochondrionBH3-interacting domain death agonistHomo sapiens (human)
extrinsic apoptotic signaling pathway via death domain receptorsBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of mitochondrial membrane potentialBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of protein-containing complex assemblyBH3-interacting domain death agonistHomo sapiens (human)
regulation of T cell proliferationBH3-interacting domain death agonistHomo sapiens (human)
signal transduction in response to DNA damageBH3-interacting domain death agonistHomo sapiens (human)
mitochondrial ATP synthesis coupled electron transportBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of apoptotic processBH3-interacting domain death agonistHomo sapiens (human)
regulation of epithelial cell proliferationBH3-interacting domain death agonistHomo sapiens (human)
neuron apoptotic processBH3-interacting domain death agonistHomo sapiens (human)
protein-containing complex assemblyBH3-interacting domain death agonistHomo sapiens (human)
establishment of protein localization to membraneBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of release of cytochrome c from mitochondriaBH3-interacting domain death agonistHomo sapiens (human)
hepatocyte apoptotic processBH3-interacting domain death agonistHomo sapiens (human)
mitochondrial outer membrane permeabilizationBH3-interacting domain death agonistHomo sapiens (human)
supramolecular fiber organizationBH3-interacting domain death agonistHomo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damageBH3-interacting domain death agonistHomo sapiens (human)
regulation of G1/S transition of mitotic cell cycleBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of fibroblast apoptotic processBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathwayBH3-interacting domain death agonistHomo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathwayBH3-interacting domain death agonistHomo sapiens (human)
apoptotic mitochondrial changesBH3-interacting domain death agonistHomo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic processBH3-interacting domain death agonistHomo sapiens (human)
response to cytokineBcl-2-like protein 1Homo sapiens (human)
negative regulation of apoptotic processBcl-2-like protein 1Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsBcl-2-like protein 1Homo sapiens (human)
ovarian follicle developmentBcl-2-like protein 1Homo sapiens (human)
in utero embryonic developmentBcl-2-like protein 1Homo sapiens (human)
release of cytochrome c from mitochondriaBcl-2-like protein 1Homo sapiens (human)
endocytosisBcl-2-like protein 1Homo sapiens (human)
germ cell developmentBcl-2-like protein 1Homo sapiens (human)
spermatogenesisBcl-2-like protein 1Homo sapiens (human)
male gonad developmentBcl-2-like protein 1Homo sapiens (human)
apoptotic mitochondrial changesBcl-2-like protein 1Homo sapiens (human)
fertilizationBcl-2-like protein 1Homo sapiens (human)
regulation of cytokinesisBcl-2-like protein 1Homo sapiens (human)
positive regulation of mononuclear cell proliferationBcl-2-like protein 1Homo sapiens (human)
ectopic germ cell programmed cell deathBcl-2-like protein 1Homo sapiens (human)
regulation of growthBcl-2-like protein 1Homo sapiens (human)
negative regulation of apoptotic processBcl-2-like protein 1Homo sapiens (human)
negative regulation of neuron apoptotic processBcl-2-like protein 1Homo sapiens (human)
dendritic cell proliferationBcl-2-like protein 1Homo sapiens (human)
response to cycloheximideBcl-2-like protein 1Homo sapiens (human)
regulation of mitochondrial membrane permeabilityBcl-2-like protein 1Homo sapiens (human)
epithelial cell proliferationBcl-2-like protein 1Homo sapiens (human)
negative regulation of developmental processBcl-2-like protein 1Homo sapiens (human)
neuron apoptotic processBcl-2-like protein 1Homo sapiens (human)
defense response to virusBcl-2-like protein 1Homo sapiens (human)
regulation of mitochondrial membrane potentialBcl-2-like protein 1Homo sapiens (human)
cellular response to amino acid stimulusBcl-2-like protein 1Homo sapiens (human)
cellular response to alkaloidBcl-2-like protein 1Homo sapiens (human)
cellular response to gamma radiationBcl-2-like protein 1Homo sapiens (human)
apoptotic process in bone marrow cellBcl-2-like protein 1Homo sapiens (human)
negative regulation of release of cytochrome c from mitochondriaBcl-2-like protein 1Homo sapiens (human)
dendritic cell apoptotic processBcl-2-like protein 1Homo sapiens (human)
hepatocyte apoptotic processBcl-2-like protein 1Homo sapiens (human)
negative regulation of execution phase of apoptosisBcl-2-like protein 1Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damageBcl-2-like protein 1Homo sapiens (human)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathwayBcl-2-like protein 1Homo sapiens (human)
negative regulation of protein localization to plasma membraneBcl-2-like protein 1Homo sapiens (human)
negative regulation of reproductive processBcl-2-like protein 1Homo sapiens (human)
negative regulation of dendritic cell apoptotic processBcl-2-like protein 1Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandBcl-2-like protein 1Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathwayBcl-2-like protein 1Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damageBcl-2-like protein 1Homo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligandBcl-2-like protein 1Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic processBcl-2-like protein 1Homo sapiens (human)
DNA damage responseInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
response to cytokineInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
cell fate determinationInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
negative regulation of autophagyInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
cellular homeostasisInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
positive regulation of apoptotic processInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
negative regulation of apoptotic processInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
protein transmembrane transportInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligandInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathwayInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
negative regulation of anoikisInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic processInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
mitochondrial fusionInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
release of cytochrome c from mitochondriaInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damageInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
B cell homeostasisBcl-2 homologous antagonist/killerHomo sapiens (human)
B cell apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
release of cytochrome c from mitochondriaBcl-2 homologous antagonist/killerHomo sapiens (human)
blood vessel remodelingBcl-2 homologous antagonist/killerHomo sapiens (human)
myeloid cell homeostasisBcl-2 homologous antagonist/killerHomo sapiens (human)
B cell negative selectionBcl-2 homologous antagonist/killerHomo sapiens (human)
apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
mitochondrial fusionBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of cell population proliferationBcl-2 homologous antagonist/killerHomo sapiens (human)
response to xenobiotic stimulusBcl-2 homologous antagonist/killerHomo sapiens (human)
response to fungusBcl-2 homologous antagonist/killerHomo sapiens (human)
response to mycotoxinBcl-2 homologous antagonist/killerHomo sapiens (human)
response to UV-CBcl-2 homologous antagonist/killerHomo sapiens (human)
establishment or maintenance of transmembrane electrochemical gradientBcl-2 homologous antagonist/killerHomo sapiens (human)
response to gamma radiationBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of calcium ion transport into cytosolBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of gene expressionBcl-2 homologous antagonist/killerHomo sapiens (human)
response to organic cyclic compoundBcl-2 homologous antagonist/killerHomo sapiens (human)
endocrine pancreas developmentBcl-2 homologous antagonist/killerHomo sapiens (human)
animal organ regenerationBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of protein-containing complex assemblyBcl-2 homologous antagonist/killerHomo sapiens (human)
endoplasmic reticulum calcium ion homeostasisBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of endoplasmic reticulum calcium ion concentrationBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of peptidyl-serine phosphorylationBcl-2 homologous antagonist/killerHomo sapiens (human)
cellular response to unfolded proteinBcl-2 homologous antagonist/killerHomo sapiens (human)
cellular response to UVBcl-2 homologous antagonist/killerHomo sapiens (human)
limb morphogenesisBcl-2 homologous antagonist/killerHomo sapiens (human)
response to hydrogen peroxideBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
fibroblast apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
response to ethanolBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of proteolysisBcl-2 homologous antagonist/killerHomo sapiens (human)
regulation of mitochondrial membrane permeabilityBcl-2 homologous antagonist/killerHomo sapiens (human)
post-embryonic camera-type eye morphogenesisBcl-2 homologous antagonist/killerHomo sapiens (human)
epithelial cell proliferationBcl-2 homologous antagonist/killerHomo sapiens (human)
establishment of localization in cellBcl-2 homologous antagonist/killerHomo sapiens (human)
regulation of cell cycleBcl-2 homologous antagonist/killerHomo sapiens (human)
regulation of mitochondrial membrane potentialBcl-2 homologous antagonist/killerHomo sapiens (human)
vagina developmentBcl-2 homologous antagonist/killerHomo sapiens (human)
calcium ion transport into cytosolBcl-2 homologous antagonist/killerHomo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressBcl-2 homologous antagonist/killerHomo sapiens (human)
thymocyte apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
cellular response to mechanical stimulusBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of release of cytochrome c from mitochondriaBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of release of cytochrome c from mitochondriaBcl-2 homologous antagonist/killerHomo sapiens (human)
apoptotic signaling pathwayBcl-2 homologous antagonist/killerHomo sapiens (human)
intrinsic apoptotic signaling pathwayBcl-2 homologous antagonist/killerHomo sapiens (human)
activation of cysteine-type endopeptidase activityBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of endoplasmic reticulum unfolded protein responseBcl-2 homologous antagonist/killerHomo sapiens (human)
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayBcl-2 homologous antagonist/killerHomo sapiens (human)
apoptotic process involved in blood vessel morphogenesisBcl-2 homologous antagonist/killerHomo sapiens (human)
positive regulation of IRE1-mediated unfolded protein responseBcl-2 homologous antagonist/killerHomo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic processBcl-2 homologous antagonist/killerHomo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligandBcl-2 homologous antagonist/killerHomo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damageBcl-2 homologous antagonist/killerHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (18)

Processvia Protein(s)Taxonomy
death receptor bindingBH3-interacting domain death agonistHomo sapiens (human)
protein bindingBH3-interacting domain death agonistHomo sapiens (human)
ubiquitin protein ligase bindingBH3-interacting domain death agonistHomo sapiens (human)
protein bindingBcl-2-like protein 1Homo sapiens (human)
protein kinase bindingBcl-2-like protein 1Homo sapiens (human)
identical protein bindingBcl-2-like protein 1Homo sapiens (human)
BH3 domain bindingBcl-2-like protein 1Homo sapiens (human)
BH domain bindingBcl-2-like protein 1Homo sapiens (human)
protein bindingInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
protein transmembrane transporter activityInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
protein heterodimerization activityInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
BH3 domain bindingInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
channel activityInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
BH domain bindingInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
molecular_functionBcl-2 homologous antagonist/killerHomo sapiens (human)
protein bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
porin activityBcl-2 homologous antagonist/killerHomo sapiens (human)
heat shock protein bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
identical protein bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
protein homodimerization activityBcl-2 homologous antagonist/killerHomo sapiens (human)
transmembrane transporter bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
protein-containing complex bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
metal ion bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
protein heterodimerization activityBcl-2 homologous antagonist/killerHomo sapiens (human)
protein-folding chaperone bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
BH domain bindingBcl-2 homologous antagonist/killerHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (16)

Processvia Protein(s)Taxonomy
mitochondrial outer membraneBH3-interacting domain death agonistHomo sapiens (human)
cytosolBH3-interacting domain death agonistHomo sapiens (human)
membraneBH3-interacting domain death agonistHomo sapiens (human)
mitochondrionBH3-interacting domain death agonistHomo sapiens (human)
cytosolBH3-interacting domain death agonistHomo sapiens (human)
cytoplasmBcl-2-like protein 1Homo sapiens (human)
mitochondrionBcl-2-like protein 1Homo sapiens (human)
mitochondrial outer membraneBcl-2-like protein 1Homo sapiens (human)
mitochondrial inner membraneBcl-2-like protein 1Homo sapiens (human)
mitochondrial matrixBcl-2-like protein 1Homo sapiens (human)
endoplasmic reticulumBcl-2-like protein 1Homo sapiens (human)
centrosomeBcl-2-like protein 1Homo sapiens (human)
cytosolBcl-2-like protein 1Homo sapiens (human)
synaptic vesicle membraneBcl-2-like protein 1Homo sapiens (human)
nuclear membraneBcl-2-like protein 1Homo sapiens (human)
Bcl-2 family protein complexBcl-2-like protein 1Homo sapiens (human)
mitochondrial outer membraneBcl-2-like protein 1Homo sapiens (human)
nucleusInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
nucleoplasmInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
cytoplasmInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
mitochondrionInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
mitochondrial outer membraneInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
cytosolInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
membraneInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
Bcl-2 family protein complexInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
mitochondrial outer membraneInduced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)
mitochondrial outer membraneBcl-2 homologous antagonist/killerHomo sapiens (human)
mitochondrionBcl-2 homologous antagonist/killerHomo sapiens (human)
mitochondrial outer membraneBcl-2 homologous antagonist/killerHomo sapiens (human)
endoplasmic reticulumBcl-2 homologous antagonist/killerHomo sapiens (human)
cytosolBcl-2 homologous antagonist/killerHomo sapiens (human)
Bcl-2 family protein complexBcl-2 homologous antagonist/killerHomo sapiens (human)
BAK complexBcl-2 homologous antagonist/killerHomo sapiens (human)
pore complexBcl-2 homologous antagonist/killerHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (9)

Assay IDTitleYearJournalArticle
AID1166893Inhibition of Bcl-xL/Bak (unknown origin) interaction2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1.
AID1635028Inhibition of His-tagged Bcl-xL/5-carboxyfluorescein-Bak (unknown origin) after 1 hr by fluorescence polarization assay2016Journal of natural products, Apr-22, Volume: 79, Issue:4
Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.
AID421902Displacement of fluorescent-tagged BH3 domain of Bak from Bcl-xL by fluorescence polarization assay2009Journal of natural products, Mar-27, Volume: 72, Issue:3
A Dimeric sesquiterpenoid from a Malaysian Meiogyne as a new inhibitor of Bcl-xL/BakBH3 domain peptide interaction.
AID1166894Inhibition of Mcl1/Bid (unknown origin) interaction2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1.
AID1635029Inhibition of His-tagged Mcl-1/5-carboxyfluorescein-Bid (unknown origin) after 1 hr by fluorescence polarization assay2016Journal of natural products, Apr-22, Volume: 79, Issue:4
Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions.
AID421903Cytotoxicity against human KB cells2009Journal of natural products, Mar-27, Volume: 72, Issue:3
A Dimeric sesquiterpenoid from a Malaysian Meiogyne as a new inhibitor of Bcl-xL/BakBH3 domain peptide interaction.
AID1166898Cytotoxicity against BL2 cells (unknown origin) assessed as cell killing after 24 hrs by MTT assay2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1.
AID1166899Cytotoxicity against BL2/B95 cells (unknown origin) assessed as cell killing after 24 hrs by MTT assay2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1.
AID1166900Cytotoxicity against Remb1 cells (unknown origin) assessed as cell killing after 24 hrs by MTT assay2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.75

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.75 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.83 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.75)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
decalin
decalin: RN given refers to cpd without isomeric designation; don't confuse with decaline which has a nitrogen at the juncture of the two rings;. trans-decalin : The trans-stereoisomer of decalin.. decalin : An ortho-fused bicyclic hydrocarbon that is the decahydro- derivative of naphthalene.		2.1110ortho-fused bicyclic hydrocarbonsolvent
3-hydroxybutanal
[no description available]		2.1110
2-cyclohexen-1-one
2-cyclohexen-1-one: RN given refers to unlabeled cpd with specified locant for double bond. cyclohexenone : The parent compound of the cyclohexenones, composed of cyclohexanone having one double bond in the ring.. cyclohex-2-enone : A cyclohexenone having its C=C double bond at the 2-position.		2.1110cyclohexenone
tiletamine hydrochloride
Cyclohexanones: Cyclohexane ring substituted by one or more ketones in any position.. cyclohexanones : Any alicyclic ketone based on a cyclohexane skeleton and its substituted derivatives thereof.		2.1110
6-n-tridecylsalicylic acid
6-n-tridecylsalicylic acid: structure given in first source		2.1310hydroxybenzoic acid
sesquiterpenes
[no description available]		3.3460
abt-737
[no description available]		2.1310aromatic amine;
aryl sulfide;
biphenyls;
C-nitro compound;
monochlorobenzenes;
N-arylpiperazine;
N-sulfonylcarboxamide;
secondary amino compound;
tertiary amino compound		anti-allergic agent;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor
ConditionIndicatedRelationship StrengthStudiesTrials
chemdatabank.com