fluciclovine-f-18 and Penile-Neoplasms

An 85-year-old asymptomatic man with suspected biochemical recurrence of prostate cancer underwent an F-fluciclovine PET/CT scan, which revealed a solitary suspicious tracer uptake in the dorsal right corporal body of the proximal pendulous penis. The patient underwent ultrasound-guided fine-needle aspiration of the penile lesion, which revealed metastatic prostate cancer. The patient had definitive external beam radiation therapy 3 years before the examination. At the time of scan, the prostatic-specific antigen (PSA) was only 1.0 ng/mL, although the PSA doubling time was 2.6 months. It is unusual to detect a solitary penile metastasis in a patient with a low level of PSA.

Topics: Aged, 80 and over; Carboxylic Acids; Cyclobutanes; Humans; Male; Penile Neoplasms; Positron Emission Tomography Computed Tomography; Prostate-Specific Antigen; Prostatic Neoplasms

Uncommon penile metastasis from prostate cancer has been reported on PET/CT imaging with F-FDG, F-fluorocholine, C-choline, and Ga-PSMA. The author presents an additional case of F-fluciclovine PET/CT depiction of proximal and distal cavernosal metastases from prostate cancer with corresponding contrast-enhanced CT findings.

Topics: Carboxylic Acids; Cyclobutanes; Humans; Male; Penile Neoplasms; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms

Topics: Aged; Carboxylic Acids; Carcinoma, Squamous Cell; Cyclobutanes; Humans; Male; Neoplasm Recurrence, Local; Penile Neoplasms; Positron Emission Tomography Computed Tomography; Prognosis; Prostatic Neoplasms