| Assay ID | Title | Year | Journal | Article |
|---|
| AID148729 | Compound was tested for the change in the Opioid receptor kappa 1 binding affinity (Ki(mut)/Ki(wild) for I294K point mutations. | 1998 | Journal of medicinal chemistry, Nov-19, Volume: 41, Issue:24
| Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists. |
| AID238876 | Inhibitory constant against human Opioid receptor kappa using [3H]diprenorphine as radio ligand | 2005 | Bioorganic & medicinal chemistry letters, May-16, Volume: 15, Issue:10
| Arylacetamide kappa opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity. |
| AID148691 | Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membrane | 1994 | Journal of medicinal chemistry, Sep-02, Volume: 37, Issue:18
| Isothiocyanate-substituted kappa-selective opioid receptor ligands derived from N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl] phenylacetamide. |
| AID243692 | Percent inhibition against human Opioid receptor mu 1 using [3H]diprenorphine as radio ligand | 2005 | Bioorganic & medicinal chemistry letters, May-16, Volume: 15, Issue:10
| Arylacetamide kappa opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity. |
| AID149749 | Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membrane | 1994 | Journal of medicinal chemistry, Sep-02, Volume: 37, Issue:18
| Isothiocyanate-substituted kappa-selective opioid receptor ligands derived from N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl] phenylacetamide. |
| AID241920 | Inhibition of cytochrome P450 2D6 was determined using MAMC (7-methoxy-4-aminomethyl-coumarin) as substrate | 2005 | Bioorganic & medicinal chemistry letters, May-16, Volume: 15, Issue:10
| Arylacetamide kappa opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity. |
| AID148725 | Compound was tested for the change in the Opioid receptor kappa 1 binding affinity (Ki(mut)/Ki(wild) for E297A point mutations. | 1998 | Journal of medicinal chemistry, Nov-19, Volume: 41, Issue:24
| Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists. |
| AID141489 | Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membrane | 1994 | Journal of medicinal chemistry, Sep-02, Volume: 37, Issue:18
| Isothiocyanate-substituted kappa-selective opioid receptor ligands derived from N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl] phenylacetamide. |
| AID148620 | Tested for inhibitory concentration against [3H]bremazocine binding to total sites of opioid receptor in guinea pig brain membrane | 1994 | Journal of medicinal chemistry, Sep-02, Volume: 37, Issue:18
| Isothiocyanate-substituted kappa-selective opioid receptor ligands derived from N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl] phenylacetamide. |
| AID240265 | Agonist activity assessed by ability to stimulate [35S]GTP gammaS binding to opioid receptor kappa in human membranes | 2005 | Bioorganic & medicinal chemistry letters, May-16, Volume: 15, Issue:10
| Arylacetamide kappa opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity. |
| AID148726 | Compound was tested for the change in the Opioid receptor kappa 1 binding affinity (Ki(mut)/Ki(wild) for G319V point mutations. | 1998 | Journal of medicinal chemistry, Nov-19, Volume: 41, Issue:24
| Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists. |
| AID148268 | Tested for percentage specific binding of compound at 10 nM against [3H]U-69593 on washed kappa-opioid receptor binding site | 1994 | Journal of medicinal chemistry, Sep-02, Volume: 37, Issue:18
| Isothiocyanate-substituted kappa-selective opioid receptor ligands derived from N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl] phenylacetamide. |
| AID148727 | Compound was tested for the change in the Opioid receptor kappa 1 binding affinity (Ki(mut)/Ki(wild) for H291A point mutations. | 1998 | Journal of medicinal chemistry, Nov-19, Volume: 41, Issue:24
| Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists. |
| AID148266 | Tested for percentage specific binding of compound at 10 nM against [3H]U-69593 on kappa-opioid receptor binding site protected with 1 uM naloxone | 1994 | Journal of medicinal chemistry, Sep-02, Volume: 37, Issue:18
| Isothiocyanate-substituted kappa-selective opioid receptor ligands derived from N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl] phenylacetamide. |
| AID148267 | Tested for percentage specific binding of compound at 10 nM against [3H]U-69593 on unwashed kappa-opioid receptor binding site | 1994 | Journal of medicinal chemistry, Sep-02, Volume: 37, Issue:18
| Isothiocyanate-substituted kappa-selective opioid receptor ligands derived from N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl] phenylacetamide. |
| AID148723 | Compound was tested for the change in the Opioid receptor kappa 1 binding affinity (Ki(mut)/Ki(wild) for D138A point mutations. | 1998 | Journal of medicinal chemistry, Nov-19, Volume: 41, Issue:24
| Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists. |
| AID243720 | Percent inhibition against human Opioid receptor delta 1 using [3H]diprenorphine as radio ligand | 2005 | Bioorganic & medicinal chemistry letters, May-16, Volume: 15, Issue:10
| Arylacetamide kappa opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity. |
| AID148728 | Compound was tested for the change in the Opioid receptor kappa 1 binding affinity (Ki(mut)/Ki(wild) for I294A point mutations. | 1998 | Journal of medicinal chemistry, Nov-19, Volume: 41, Issue:24
| Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists. |
| AID148720 | Compound was tested for the change in the Opioid receptor kappa 1 binding affinity (Ki(mut)/Ki(wild) for A298H point mutations. | 1998 | Journal of medicinal chemistry, Nov-19, Volume: 41, Issue:24
| Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |