| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 3 | 0 | 0 | 3 |
| dopamine D1 receptor | 1 | 0 | 0 | 1 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 5 | 0 | 0 | 5 |
| USP1 protein, partial | 3 | 0 | 0 | 3 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| AR protein | 7 | 0 | 0 | 7 |
| regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 7 | 0 | 0 | 7 |
| retinoic acid nuclear receptor alpha variant 1 | 5 | 0 | 0 | 5 |
| retinoid X nuclear receptor alpha | 5 | 0 | 0 | 5 |
| farnesoid X nuclear receptor | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 8 | 0 | 0 | 8 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 3 | 0 | 0 | 3 |
| heat shock protein beta-1 | 2 | 0 | 0 | 2 |
| flap endonuclease 1 | 3 | 0 | 0 | 3 |
| geminin | 7 | 0 | 0 | 7 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Histone deacetylase 3 | 0 | 3 | 0 | 3 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Histone deacetylase 4 | 0 | 2 | 0 | 2 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| Histone deacetylase 1 | 0 | 3 | 0 | 3 |
| Histone deacetylase 7 | 0 | 2 | 0 | 2 |
| Histone deacetylase 2 | 0 | 3 | 0 | 3 |
| Polyamine deacetylase HDAC10 | 0 | 1 | 0 | 1 |
| Histone deacetylase 11 | 0 | 2 | 0 | 2 |
| Ataxin-2 | 3 | 0 | 0 | 3 |
| Histone deacetylase 8 | 0 | 2 | 0 | 2 |
| Histone deacetylase 6 | 0 | 2 | 0 | 2 |
| Histone deacetylase 9 | 0 | 1 | 0 | 1 |
| Histone deacetylase 5 | 0 | 2 | 0 | 2 |
| ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| Bile salt export pump | 0 | 7 | 0 | 7 |
| Muscarinic acetylcholine receptor M2 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M4 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M5 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 1 | 0 | 1 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 4 | 0 | 0 | 4 |
| Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 6 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 1 | 0 | 2 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 7 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 9 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase, alpha family | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 13 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 1 | 0 | 2 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 5 | 0 | 5 |
| Multidrug resistance-associated protein 4 | 0 | 5 | 0 | 5 |
| Spike glycoprotein | 3 | 0 | 0 | 3 |
| Canalicular multispecific organic anion transporter 1 | 0 | 5 | 0 | 5 |
| GLI family zinc finger 3 | 7 | 0 | 0 | 7 |
| estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 7 | 0 | 0 | 7 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 4 | 0 | 0 | 4 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Cellular tumor antigen p53 | 4 | 0 | 0 | 4 |
| TAR DNA-binding protein 43 | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
| PPM1D protein | 3 | 0 | 0 | 3 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
| progesterone receptor | 4 | 0 | 0 | 4 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 4 | 0 | 0 | 4 |
| G | 4 | 0 | 0 | 4 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| IDH1 | 3 | 0 | 0 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 2 | 4 | 0 | 0 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| Interferon beta | 6 | 0 | 0 | 6 |
| HLA class I histocompatibility antigen, B alpha chain | 4 | 0 | 0 | 4 |
| Glucocorticoid receptor | 0 | 4 | 1 | 10 |
| Glycine receptor subunit alpha-1 | 0 | 4 | 0 | 4 |
| Androgen receptor | 0 | 3 | 0 | 3 |
| Glycine receptor subunit beta | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-2 | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-3 | 0 | 4 | 0 | 4 |
| Inositol hexakisphosphate kinase 1 | 4 | 0 | 0 | 4 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| cytochrome P450 2C9, partial | 4 | 0 | 0 | 4 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 5 | 0 | 0 | 5 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| Nuclear receptor corepressor 1 | 0 | 1 | 0 | 1 |
| Integrin beta-1 | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 2 | 0 | 2 |
| Leukotriene A-4 hydrolase | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Integrin alpha-4 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Nuclear receptor corepressor 2 | 0 | 1 | 0 | 1 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| GALC protein | 1 | 0 | 0 | 1 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 3 | 0 | 0 | 3 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| mu-type opioid receptor isoform MOR-1 | 0 | 0 | 1 | 1 |
| Vpr | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 0 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| luciferase | 0 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Estrogen receptor | 0 | 2 | 0 | 2 |
| Progesterone receptor | 0 | 2 | 0 | 3 |
| Glucocorticoid receptor | 0 | 1 | 1 | 2 |
| Glucocorticoid receptor | 0 | 0 | 1 | 1 |
| Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
| Mineralocorticoid receptor | 0 | 2 | 1 | 3 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Glutamine synthetase | 0 | 0 | 1 | 1 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Histamine H1 receptor | 0 | 0 | 1 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Nociceptin receptor | 0 | 0 | 1 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Estrogen receptor beta | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 12 | 0 | 0 | 0 | 1 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 3 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 14 | 0 | 0 | 0 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| polyprotein | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| histone deacetylase 9 isoform 3 | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 0 | 2 | 0 | 2 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| streptokinase A precursor | 0 | 0 | 1 | 1 |
| twin arginine protein translocation system - TatA protein | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| 30S ribosomal protein S6 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S7 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L15 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L10 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L11 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L7/L12 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L19 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L1 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L20 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L27 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L28 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L29 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L31 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L31 type B | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L32 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L33 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L34 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L35 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L36 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S10 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S11 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S12 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S13 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S16 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S18 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S19 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S20 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S2 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S3 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S4 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S5 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S8 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S9 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L13 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L14 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L16 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L23 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S15 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L17 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L21 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L30 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L6 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S14 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S17 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S1 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L18 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| 50S ribosomal protein L2 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L3 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L24 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L4 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L22 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L5 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| 30S ribosomal protein S21 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L25 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L36 2 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| Protein-arginine deiminase type-4 | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |