Compounds > fluacrypyrim
Page last updated: 2024-11-12

fluacrypyrim

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Description

fluacrypyrim: a STAT3 activation inhibitor and antineoplastic agent; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9954185
CHEMBL ID2392676
CHEBI ID38591
SCHEMBL ID83958
SCHEMBL ID5997532
MeSH IDM0549207

Synonyms (28)

Synonym
methyl (2e)-2-[2-({[2-(propan-2-yl)oxy-6-(trifluoromethyl)pyrimidin-4-yl]oxy}methyl)phenyl]-3-methoxyacrylate
methyl (2e)-2-[2-({[2-isopropoxy-6-(trifluoromethyl)pyrimidin-4-yl]oxy}methyl)phenyl]-3-methoxyacrylate
229977-93-9
fluacrypyrim
CHEBI:38591 ,
unii-fhj1l9vjth
fluacrypyrim [iso]
fhj1l9vjth ,
C18595
CHEMBL2392676
methyl (e)-2-(2-(((2-isopropoxy-6-trifluoromethylpyrimidin-4-yl)oxy)methyl)phenyl)-3-methoxy-2-propenoate
methyl (e)-2-(2-(2-isopropoxy-6-(trifluoromethyl)pyrimidin-4-yloxymethyl)phenyl)-3-methoxyacrylate
benzeneacetic acid, .alpha.-(methoxymethylene)-2-(((2-(1-methylethoxy)-6-(trifluoromethyl)-4-pyrimidinyl)oxy)methyl)-, methyl ester, (.alpha.e)-
SCHEMBL83958
SCHEMBL5997532
DTXSID4058027
fluacryppyrim
AC-25666
AKOS025401798
178813-81-5
J-521368
fluacrypyrim, pestanal(r), analytical standard
(e)-methyl 2-(2-((2-isopropoxy-6-(trifluoromethyl)pyrimidin-4-yloxy)methyl)phenyl)-3-methoxyacrylate
fluacrypyrim 100 microg/ml in acetonitrile
Q22807579
benzeneacetic acid,a-(methoxymethylene)-2-[[[2-(1-methylethoxy)-6-(trifluoromethyl)-4-pyrimidinyl]oxy]methyl]-, methyl ester, (ae)-
methyl (e)-3-methoxy-2-[2-[[2-propan-2-yloxy-6-(trifluoromethyl)pyrimidin-4-yl]oxymethyl]phenyl]prop-2-enoate
benzeneacetic acid, ?-(methoxymethylene)-2-[[[2-(1-methylethoxy)-6-(trifluoromethyl)-4-pyrimidinyl]oxy]methyl]-, methyl ester, (.alpha.e)-

Research Excerpts

Treatment

ExcerptReferenceRelevance
"Fluacrypyrim treatment abolished the picotee pattern and eliminated site-specific differences in the levels of anthocyanin-related compounds, CHSA expression, and CHSA small interfering RNA (siRNA)."( Inhibition of post-transcriptional gene silencing of chalcone synthase genes in petunia picotee petals by fluacrypyrim.
Ban, Y; Higashi, K; Morita, Y; Nakatsuka, T; Nakayama, M; Nishihara, M; Ogawa, M, 2019)		1.45
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
mitochondrial cytochrome-bc1 complex inhibitornull
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (5)

ClassDescription
pyrimidinesAny compound having a pyrimidine as part of its structure.
organofluorine acaricide
methyl esterAny carboxylic ester resulting from the formal condensation of a carboxy group with methanol.
enoate esterAn alpha,beta-unsaturated carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) in which the ester C=O function is conjugated to a C=C double bond at the alpha,beta position.
enol etherEthers ROR' where R has a double bond adjacent to the oxygen of the ether linkage.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (57)

Assay IDTitleYearJournalArticle
AID1104755Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) infected kidney bean plant assessed as mortality at 100 g a.i./ha measured after 7 days in field conditions relative to control2010Pest management science, Nov, Volume: 66, Issue:11
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties.
AID1103775Resistance ratio of LC50 for bifenazate-susceptible Tetranychus urticae LS-VL (two-spotted spider mite) to LC50 for Tetranychus urticae GSS 2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1111773Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) in kidney bean leaf assessed as mortality at 2.5 mg/L measured after 72 hr of spray2011Pest management science, Sep, Volume: 67, Issue:9
The discovery of SYP-10913 and SYP-11277: novel strobilurin acaricides.
AID1103755Toxicity against adult Tetranychus urticae BEL1 (two-spotted spider mite) in bean leaves assessed as mortality treated 24 hr after 2000 mg/L cytochrome P450 monoxygenase inhibitor, PBO application2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103767Resistance ratio of LC50 for Tetranychus urticae (two-spotted spider mite) HOL4 harboring mitochondrial G126S Cytb mutation to LC50 for Tetranychus urticae GSS 2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103777Toxicity against adult Tetranychus urticae HOL4 (two-spotted spider mite) harboring mitochondrial G126S Cytb mutation in compound pretreated bean leaves assessed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103778Toxicity against adult Tetranychus urticae HOL3 (two-spotted spider mite) harboring mitochondrial P262T Cytb heteroplasmic mutation in compound pretreated bean leaves assessed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1111772Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) in kidney bean leaf assessed as mortality at 1.25 mg/L measured after 72 hr of spray2011Pest management science, Sep, Volume: 67, Issue:9
The discovery of SYP-10913 and SYP-11277: novel strobilurin acaricides.
AID1104753Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) infected kidney bean plant assessed as mortality at 100 g a.i./ha measured after 21 days in field conditions relative to control2010Pest management science, Nov, Volume: 66, Issue:11
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties.
AID753560Cytotoxicity against human A549 cells assessed as growth inhibition by SRB assay2013Bioorganic & medicinal chemistry letters, Jun-15, Volume: 23, Issue:12
Synthesis of novel strobilurin-pyrimidine derivatives and their antiproliferative activity against human cancer cell lines.
AID1103750Synergism ratio of LC50 for adult Tetranychus urticae GSS (two-spotted spider mite) to LC50 for adult Tetranychus urticae GSS in presence of 2000 mg/L GST inhibitor, DEM application2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103760Toxicity against adult Tetranychus urticae GSS (two-spotted spider mite) in bean leaves assessed as mortality treated 24 hr after 1000 mg/L esterase inhibitor, DEF application2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1104754Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) infected kidney bean plant assessed as mortality at 100 g a.i./ha measured after 14 days in field conditions relative to control2010Pest management science, Nov, Volume: 66, Issue:11
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties.
AID1111770Acaricidal activity against eggs of Tetranychus cinnabarinus (carmine spider mite) in kidney bean leaf assessed as unhatched eggs measured after 120 hr2011Pest management science, Sep, Volume: 67, Issue:9
The discovery of SYP-10913 and SYP-11277: novel strobilurin acaricides.
AID1104752Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) infected kidney bean plant assessed as mortality at 50 g a.i./ha measured after 3 days in field conditions relative to control2010Pest management science, Nov, Volume: 66, Issue:11
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties.
AID1103781Toxicity against adult bifenazate-resistant Tetranychus urticae BR-VL (two-spotted spider mite) harboring mitochondrial G126S, S141F and D161G Cytb mutation in compound pretreated bean leaves assessed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103763Toxicity against female adult Tetranychus urticae (two-spotted spider mite) F1 progeny generated from reciprocal cross between female GSS and male BEL1 in compound pretreated bean leaves assesed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103758Toxicity against adult Tetranychus urticae BR-VL (two-spotted spider mite) in bean leaves assessed as mortality treated 24 hr after 2000 mg/L cytochrome P450 monoxygenase inhibitor, PBO application2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103774Resistance ratio of LC50 for Tetranychus urticae WI (two-spotted spider mite) to LC50 for Tetranychus urticae GSS 2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1111776Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) in kidney bean leaf assessed as mortality at 40 mg/L measured after 72 hr of spray2011Pest management science, Sep, Volume: 67, Issue:9
The discovery of SYP-10913 and SYP-11277: novel strobilurin acaricides.
AID1103754Toxicity against adult Tetranychus urticae BEL1 (two-spotted spider mite) in bean leaves assessed as mortality treated 24 hr after 2000 mg/L esterase inhibitor, DEF application2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103761Toxicity against adult Tetranychus urticae GSS (two-spotted spider mite) in bean leaves assessed as mortality treated 24 hr after 2000 mg/L cytochrome P450 monoxygenase inhibitor, PBO application2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1104761Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) infected kidney bean leaf assessed as mortality at 40 mg/l measured after 48 hr in greenhouse conditions relative to control2010Pest management science, Nov, Volume: 66, Issue:11
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties.
AID1103753Toxicity against adult Tetranychus urticae BEL1 (two-spotted spider mite) in bean leaves assessed as mortality treated 24 hr after 2000 mg/L GST inhibitor, DEM application2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1104751Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) infected kidney bean plant assessed as mortality at 50 g a.i./ha measured after 7 days in field conditions relative to control2010Pest management science, Nov, Volume: 66, Issue:11
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties.
AID1103765Toxicity against female adult Tetranychus urticae (two-spotted spider mite) F1 progeny generated from reciprocal cross between female GSS and male BR-VL in compound pretreated bean leaves assesed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103751Synergism ratio of LC50 for adult Tetranychus urticae GSS (two-spotted spider mite) to LC50 for adult Tetranychus urticae GSS in presence of 1000 mg/L esterase inhibitor, DEF application2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103773Resistance ratio of LC50 for Tetranychus urticae MR-VL (two-spotted spider mite) to LC50 for Tetranychus urticae GSS 2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1104749Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) infected kidney bean plant assessed as mortality at 50 g a.i./ha measured after 21 days in field conditions relative to control2010Pest management science, Nov, Volume: 66, Issue:11
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties.
AID1103764Toxicity against female adult Tetranychus urticae (two-spotted spider mite) F1 progeny generated from reciprocal cross between female BR-VL and male GSS in compound pretreated bean leaves assesed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103769Resistance ratio of LC50 for Tetranychus urticae HOL2 (two-spotted spider mite) harboring mitochondrial G126S Cytb mutation to LC50 for Tetranychus urticae GSS 2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103782Toxicity against adult METI-resistant Tetranychus urticae MR-VP (two-spotted spider mite) in compound pretreated bean leaves assessed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103757Toxicity against adult Tetranychus urticae BR-VL (two-spotted spider mite) in bean leaves assessed as mortality treated 24 hr after 2000 mg/L esterase inhibitor, DEF application2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1111775Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) in kidney bean leaf assessed as mortality at 10 mg/L measured after 72 hr of spray2011Pest management science, Sep, Volume: 67, Issue:9
The discovery of SYP-10913 and SYP-11277: novel strobilurin acaricides.
AID1104760Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) infected kidney bean leaf assessed as mortality at 10 mg/l measured after 48 hr in greenhouse conditions relative to control2010Pest management science, Nov, Volume: 66, Issue:11
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties.
AID1103756Toxicity against adult Tetranychus urticae BR-VL (two-spotted spider mite) in bean leaves assessed as mortality treated 24 hr after 2000 mg/L GST inhibitor, DEM application2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103752Synergism ratio of LC50 for adult Tetranychus urticae GSS (two-spotted spider mite) to LC50 for adult Tetranychus urticae GSS in presence of 2000 mg/L cytochrome P450 monoxygenase inhibitor, PBO2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103780Toxicity against adult Tetranychus urticae HOL1 (two-spotted spider mite) harboring mitochondrial G126S and I136T Cytb mutation in compound pretreated bean leaves assessed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103768Resistance ratio of LC50 for Tetranychus urticae HOL3 (two-spotted spider mite) harboring mitochondrial P262T Cytb heteroplasmic mutation to LC50 for Tetranychus urticae GSS2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103779Toxicity against adult Tetranychus urticae HOL2 (two-spotted spider mite) harboring mitochondrial G126S Cytb mutation in compound pretreated bean leaves assessed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103766Resistance ratio of LC50 for bifenazate-resistant Tetranychus urticae (two-spotted spider mite) BEL1 harboring mitochondrial P262T Cytb fixed mutation to LC50 for Tetranychus urticae GSS 2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID753558Cytotoxicity against human HL60 cells assessed as growth inhibition by MTT assay2013Bioorganic & medicinal chemistry letters, Jun-15, Volume: 23, Issue:12
Synthesis of novel strobilurin-pyrimidine derivatives and their antiproliferative activity against human cancer cell lines.
AID1111774Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) in kidney bean leaf assessed as mortality at 5 mg/L measured after 72 hr of spray2011Pest management science, Sep, Volume: 67, Issue:9
The discovery of SYP-10913 and SYP-11277: novel strobilurin acaricides.
AID1103762Toxicity against female adult Tetranychus urticae (two-spotted spider mite) F1 progeny generated from reciprocal cross between female BEL1 and male GSS in compound pretreated bean leaves assesed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103783Toxicity against adult Tetranychus urticae MR-VL (two-spotted spider mite) in compound pretreated bean leaves assessed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103786Toxicity against adult Tetranychus urticae GSS (two-spotted spider mite) in compound pretreated bean leaves assessed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1104750Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) infected kidney bean plant assessed as mortality at 50 g a.i./ha measured after 14 days in field conditions relative to control2010Pest management science, Nov, Volume: 66, Issue:11
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties.
AID1103771Resistance ratio of LC50 for bifenazate-resistant Tetranychus urticae BR-VL (two-spotted spider mite) harboring mitochondrial G126S, S141F and D161G Cytb mutation to LC50 for Tetranychus urticae GSS 2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1104756Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) infected kidney bean plant assessed as mortality at 100 g a.i./ha measured after 3 days in field conditions relative to control2010Pest management science, Nov, Volume: 66, Issue:11
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties.
AID1103770Resistance ratio of LC50 for Tetranychus urticae HOL1 (two-spotted spider mite) harboring mitochondrial G126S and I136T Cytb mutation to LC50 for Tetranychus urticae GSS2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103776Toxicity against adult bifenazate-resistant Tetranychus urticae BEL1 (two-spotted spider mite) harboring mitochondrial P262T Cytb fixed mutation in compound pretreated bean leaves assessed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103785Toxicity against adult bifenazate-susceptible Tetranychus urticae LS-VL (two-spotted spider mite) in compound pretreated bean leaves assessed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103784Toxicity against adult Tetranychus urticae WI (two-spotted spider mite) in compound pretreated bean leaves assessed as mortality2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1104762Acaricidal activity against Tetranychus cinnabarinus (carmine spider mite) infected kidney bean leaf assessed as mortality at 600 mg/l measured after 48 hr in greenhouse conditions relative to control2010Pest management science, Nov, Volume: 66, Issue:11
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties.
AID1103759Toxicity against adult Tetranychus urticae GSS (two-spotted spider mite) in bean leaves assessed as mortality treated 24 hr after 2000 mg/L GST inhibitor, DEM application2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1103772Resistance ratio of LC50 for METI-resistant Tetranychus urticae MR-VP (two-spotted spider mite) to LC50 for Tetranychus urticae GSS2009Pest management science, Apr, Volume: 65, Issue:4
Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl.
AID1111771Acaricidal activity against nymphs of Tetranychus cinnabarinus (carmine spider mite) in kidney bean leaf assessed as mortality measured after 120 hr2011Pest management science, Sep, Volume: 67, Issue:9
The discovery of SYP-10913 and SYP-11277: novel strobilurin acaricides.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.95

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index23.95 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (23.95)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
acequinocyl
acequinocyl: structure in first source. acequinocyl : An acetate ester consisting of 1,4-naphthoquinone bearing acetoxy and dodecyl substituents at positions 2 and 3 respectively.		2.05101,4-naphthoquinones;
acetate ester		acaricide;
mitochondrial cytochrome-bc1 complex inhibitor
bifenazate
bifenazate: an acaricide. bifenazate : A carboxylic ester obtained by formal condensation of 2-(4-methoxy[1,1'-biphenyl]-3-yl)hydrazinecarboxylic acid with 2-propanol.		2.0510carboxylic esteracaricide
dinoprost
Dinoprost: A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.. prostaglandin F2alpha : A prostaglandins Falpha that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15. It is a naturally occurring prostaglandin used to induce labor.		2.1510monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
fluoxastrobin
fluoxastrobin: a fungicide. fluoxastrobin : An oxime O-ether that is the O-methyl oxime of (2-{[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxy}phenyl)(5,6-dihydro-1,4,2-dioxazin-3-yl)methanone. A fungicide used for disease control of potatoes and a wide range of vegetables.		7.0510aromatic ether;
dioxazine;
monochlorobenzenes;
organofluorine compound;
oxime O-ether;
pyrimidines;
strobilurin antifungal agent		antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor
ConditionIndicatedRelationship StrengthStudiesTrials
Leucocythaemia
[description not available]		02.4720
Cancer of Lung
[description not available]		02.0810
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)		02.4720
Lung Neoplasms
Tumors or cancer of the LUNG.		02.0810
Nociceptive Pain
Dull or sharp aching pain caused by stimulated NOCICEPTORS due to tissue injury, inflammation or diseases. It can be divided into somatic or tissue pain and VISCERAL PAIN.		02.1510
Breast Cancer
[description not available]		02.0510
Breast Neoplasms
Tumors or cancer of the human BREAST.		02.0510