| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain H, Proteasome component PUP1 | 0 | 1 | 0 | 1 |
| Chain I, Proteasome component PUP3 | 0 | 1 | 0 | 1 |
| Chain K, Proteasome component PRE2 | 0 | 1 | 0 | 1 |
| Chain L, Proteasome component C5 | 0 | 1 | 0 | 1 |
| Chain K, Proteasome component PRE2 | 0 | 1 | 0 | 1 |
| Chain L, Proteasome component C5 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-11 | 0 | 3 | 0 | 3 |
| RAR-related orphan receptor gamma | 3 | 0 | 0 | 3 |
| Fumarate hydratase | 3 | 0 | 0 | 3 |
| PPM1D protein | 4 | 0 | 0 | 4 |
| TDP1 protein | 3 | 0 | 0 | 3 |
| AR protein | 4 | 0 | 0 | 4 |
| caspase 7, apoptosis-related cysteine protease | 2 | 0 | 0 | 2 |
| estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| EWS/FLI fusion protein | 5 | 0 | 0 | 5 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| retinoid X nuclear receptor alpha | 3 | 0 | 0 | 3 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| farnesoid X nuclear receptor | 3 | 0 | 0 | 3 |
| pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
| estrogen nuclear receptor alpha | 3 | 0 | 0 | 3 |
| polyprotein | 3 | 0 | 0 | 3 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
| caspase-3 | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| Caspase-7 | 2 | 0 | 0 | 2 |
| caspase-3 | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
| heat shock protein beta-1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 2 | 0 | 0 | 2 |
| 26S proteasome non-ATPase regulatory subunit 11 | 0 | 2 | 0 | 2 |
| 26S proteasome non-ATPase regulatory subunit 12 | 0 | 2 | 0 | 2 |
| 26S proteasome non-ATPase regulatory subunit 14 | 0 | 2 | 0 | 2 |
| Proteasome subunit alpha type-7 | 0 | 3 | 0 | 3 |
| Histone deacetylase 3 | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
| Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 3 |
| 26S proteasome non-ATPase regulatory subunit 3 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 12 | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| Prothrombin | 0 | 1 | 0 | 1 |
| Chymotrypsinogen A | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 2 | 0 | 2 |
| Interferon beta | 4 | 0 | 0 | 4 |
| Cellular tumor antigen p53 | 3 | 0 | 0 | 3 |
| Carbonic anhydrase 3 | 0 | 1 | 0 | 1 |
| Cathepsin B | 0 | 2 | 0 | 2 |
| Neutrophil elastase | 0 | 1 | 0 | 1 |
| Cathepsin G | 0 | 3 | 0 | 3 |
| Lysosomal protective protein | 0 | 2 | 0 | 2 |
| Chymotrypsinogen B | 0 | 1 | 0 | 1 |
| 26S proteasome regulatory subunit 6A | 0 | 2 | 0 | 2 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Nuclear factor NF-kappa-B p105 subunit | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-1 | 0 | 3 | 0 | 4 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 6 | 0 | 1 | 0 | 1 |
| Chymase | 0 | 1 | 0 | 1 |
| Proteasome subunit alpha type-1 | 0 | 3 | 0 | 3 |
| Proteasome subunit alpha type-2 | 0 | 3 | 0 | 3 |
| Proteasome subunit alpha type-3 | 0 | 3 | 0 | 3 |
| Proteasome subunit alpha type-4 | 0 | 3 | 0 | 3 |
| Proteasome subunit beta type-8 | 0 | 3 | 0 | 3 |
| Proteasome subunit beta type-8 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-9 | 0 | 3 | 0 | 3 |
| Proteasome subunit alpha type-5 | 0 | 3 | 0 | 3 |
| Proteasome subunit beta type-4 | 0 | 3 | 0 | 3 |
| Proteasome subunit beta type-6 | 0 | 3 | 0 | 3 |
| Proteasome subunit beta type-5 | 0 | 4 | 0 | 5 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 1 | 0 | 1 |
| 26S proteasome regulatory subunit 7 | 0 | 2 | 0 | 2 |
| Lon protease homolog, mitochondrial | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-10 | 0 | 3 | 0 | 3 |
| Carbonic anhydrase 7 | 0 | 1 | 0 | 1 |
| 26S proteasome regulatory subunit 6B | 0 | 2 | 0 | 2 |
| 26S proteasome non-ATPase regulatory subunit 8 | 0 | 2 | 0 | 2 |
| Proteasome subunit beta type-3 | 0 | 3 | 0 | 3 |
| Proteasome subunit beta type-2 | 0 | 3 | 0 | 4 |
| 26S proteasome non-ATPase regulatory subunit 7 | 0 | 2 | 0 | 2 |
| 26S proteasome non-ATPase regulatory subunit 4 | 0 | 2 | 0 | 2 |
| 26S proteasome complex subunit SEM1 | 0 | 2 | 0 | 2 |
| Proteasome subunit alpha type-6 | 0 | 3 | 0 | 3 |
| 26S proteasome regulatory subunit 4 | 0 | 2 | 0 | 2 |
| 26S proteasome regulatory subunit 8 | 0 | 2 | 0 | 2 |
| 26S proteasome regulatory subunit 10B | 0 | 2 | 0 | 2 |
| Beta-carbonic anhydrase 1 | 0 | 1 | 0 | 1 |
| Nuclear factor NF-kappa-B p100 subunit | 0 | 1 | 0 | 1 |
| Transcription factor p65 | 0 | 1 | 0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 2 | 0 | 2 | 0 | 2 |
| Histone deacetylase 1 | 0 | 1 | 0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 6 | 0 | 2 | 0 | 2 |
| Proteasomal ubiquitin receptor ADRM1 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 9 | 0 | 1 | 0 | 1 |
| ATP-dependent Clp protease proteolytic subunit | 0 | 2 | 2 | 4 |
| Carbonic anhydrase 13 | 0 | 1 | 0 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | 0 | 2 | 0 | 2 |
| Proteasome subunit alpha-type 8 | 0 | 3 | 0 | 3 |
| Histone deacetylase 2 | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Proteasome subunit beta type-7 | 0 | 3 | 0 | 3 |
| 26S proteasome non-ATPase regulatory subunit 1 | 0 | 2 | 0 | 2 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Carbonic anhydrase 15 | 0 | 1 | 0 | 1 |
| Histone deacetylase 8 | 0 | 1 | 0 | 1 |
| Histone deacetylase 6 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 14 | 0 | 1 | 0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 13 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 1 | 0 | 1 |
| Chain A, Vitamin D Nuclear Receptor | 0 | 0 | 1 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| Vitamin D3 receptor | 0 | 0 | 1 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| geminin | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| Vitamin D-binding protein | 0 | 0 | 1 | 1 |
| Cytochrome P450 1A2 | 0 | 0 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 2 | 0 | 3 |
| Androgen receptor | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Vitamin D3 receptor | 0 | 1 | 2 | 4 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 2 |
| Vitamin D3 receptor | 0 | 1 | 1 | 3 |
| Retinoic acid receptor RXR-alpha | 0 | 0 | 1 | 1 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
| Kappa-type opioid receptor | 0 | 0 | 1 | 1 |
| Vitamin D3 receptor | 0 | 0 | 1 | 1 |
| 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | 0 | 0 | 1 | 1 |
| Vitamin D3 receptor | 0 | 1 | 1 | 2 |
| Transporter | 0 | 1 | 0 | 1 |
| Vitamin D3 receptor A | 0 | 0 | 2 | 2 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| Proteasome subunit beta type-2 | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-1 | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| Glutathione S-transferase omega-1 | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Glycine receptor subunit alpha-1 | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 2 | 1 | 3 |
| Sodium- and chloride-dependent glycine transporter 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 2 | 1 | 3 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 2 | 1 | 3 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 2 | 1 | 3 |
| Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 2 | 1 | 3 |
| Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 2 | 1 | 3 |
| Serine racemase | 0 | 1 | 0 | 1 |
| Olfactory receptor 51E2 | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 2 | 1 | 3 |
| Sodium- and chloride-dependent glycine transporter 2 | 0 | 1 | 0 | 1 |
| Cereblon isoform 4 | 0 | 3 | 0 | 3 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| Bromodomain-containing protein 4 | 0 | 1 | 0 | 1 |
| Tyrosine-protein kinase ABL1 | 0 | 0 | 0 | 1 |
| Breakpoint cluster region protein | 0 | 0 | 0 | 1 |
| DNA-binding protein Ikaros | 0 | 0 | 1 | 4 |
| DNA damage-binding protein 1 | 0 | 2 | 1 | 3 |
| Protein cereblon | 0 | 4 | 2 | 9 |
| Zinc finger protein Aiolos | 0 | 0 | 1 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Eyes absent homolog 2 | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |