Adenomatoid Tumor

A small, circumscribed, benign tumor of the genital tract, composed of small glandlike spaces lined by flattened or cuboidal mesothelium-like cells. (From Dorland, 27th ed)

Synonym
Adenomatoid Tumor

Excerpt	Reference
"Adenomatoid tumors are regarded as a benign variant of mesothelioma."	( Hayashi, T; Kaplan, MA; Schroer, KR; Tazelaar, HD; Travis, WD, 1996)
"Adenomatoid tumors are slow growing epithelioid neoplasias with a co-expression of vimentin and cytokeratins."	( Dietterle, S; Hantschick, M; Stosiek, P, 1997)
"Adenomatoid tumors are common in the genital tract but rare in the adrenal gland."	( Jarrett, TW; Mufarrij, P; Studeman, KD; Varkarakis, IM, 2005)
"Adenomatoid tumors are benign proliferations of mesothelial origin."	( Hecht, L; Lehsnau, M, 2006)
"Adenomatoid tumors are benign mesothelial neoplasms most commonly found in the male and female genital tracts."	( Chou, HH; Chuang, WY; Hsueh, S; Jung, SM; Yeh, CJ, 2008)
"Adenomatoid tumors are rare benign neoplasms thought to be of mesothelial origin."	( Liu, W; Wu, RD; Yu, QH, 2011)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	10 (34.48)	12.5806
2000's	11 (37.93)	18.1394
2010's	5 (17.24)	28.8240
2020's	3 (10.34)	9.53

Drug	Relationship Strength	Studies
homovanillic acid	low	1
nifedipine	low	1
fluorodeoxyglucose f18	low	2
imatinib mesylate	low	1
bromochloroacetic acid	low	21
lewis x antigen	low	1

Protein Targets (215)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
RAR-related orphan receptor gamma	2	0	0	2
AR protein	3	0	0	3
aldehyde dehydrogenase 1 family, member A1	3	0	0	3
nuclear receptor subfamily 1, group I, member 3	3	0	0	3
retinoic acid nuclear receptor alpha variant 1	3	0	0	3
thyroid stimulating hormone receptor	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	3	0	0	3
Cellular tumor antigen p53	2	0	0	2
Nuclear receptor ROR-gamma	2	0	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
thioredoxin reductase	3	0	0	3
ClpP	1	0	0	1
ATAD5 protein, partial	2	0	0	2
Fumarate hydratase	2	0	0	2
NFKB1 protein, partial	2	0	0	2
GLS protein	2	0	0	2
TDP1 protein	3	0	0	3
thyroid stimulating hormone receptor	2	0	0	2
regulator of G-protein signaling 4	2	0	0	2
polyprotein	2	0	0	2
arylsulfatase A	1	0	0	1
euchromatic histone-lysine N-methyltransferase 2	2	0	0	2
lysosomal alpha-glucosidase preproprotein	1	0	0	1
chromobox protein homolog 1	2	0	0	2
M-phase phosphoprotein 8	2	0	0	2
muscarinic acetylcholine receptor M1	2	0	0	2
Solute carrier family 22 member 8	0	0	0	1
ATP-dependent phosphofructokinase	2	0	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	2	0	0	2
Luciferase	2	0	0	2
acetylcholinesterase	1	0	0	1
glp-1 receptor, partial	1	0	0	1
SMAD family member 2	1	0	0	1
SMAD family member 3	1	0	0	1
GLI family zinc finger 3	2	0	0	2
estrogen receptor 2 (ER beta)	1	0	0	1
progesterone receptor	2	0	0	2
cytochrome P450 family 3 subfamily A polypeptide 4	2	0	0	2
glucocorticoid receptor [Homo sapiens]	2	0	0	2
retinoid X nuclear receptor alpha	2	0	0	2
estrogen-related nuclear receptor alpha	2	0	0	2
farnesoid X nuclear receptor	2	0	0	2
pregnane X nuclear receptor	2	0	0	2
estrogen nuclear receptor alpha	2	0	0	2
peroxisome proliferator-activated receptor delta	2	0	0	2
IDH1	2	0	0	2
aryl hydrocarbon receptor	2	0	0	2
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
thyroid hormone receptor beta isoform 2	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
DNA polymerase iota isoform a (long)	2	0	0	2
geminin	2	0	0	2
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Voltage-dependent calcium channel gamma-2 subunit	2	0	0	2
Tyrosine-protein kinase ABL1	0	1	1	2
Cytochrome P450 3A4	0	1	0	2
Cytochrome P450 2C8	0	0	0	1
Mast/stem cell growth factor receptor Kit	0	1	1	2
Breakpoint cluster region protein	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	1	2
Glutamate receptor 2	2	0	0	2
Cytochrome P450 3A5	0	0	0	1
Spike glycoprotein	2	0	0	2
ATPase family AAA domain-containing protein 5	2	0	0	2
Ataxin-2	2	0	0	2
Chain A, Beta-lactamase	1	0	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Chain A, 2-oxoglutarate Oxygenase	1	0	0	1
pregnane X receptor	1	0	0	1
phosphopantetheinyl transferase	1	0	0	1
hypoxia-inducible factor 1 alpha subunit	1	0	0	1
USP1 protein, partial	1	0	0	1
Microtubule-associated protein tau	1	0	0	1
Thrombopoietin	1	0	0	1
Smad3	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
hypothetical protein, conserved	1	0	0	1
nonstructural protein 1	1	0	0	1
G	1	0	0	1
cytochrome P450 2D6	1	0	0	1
67.9K protein	1	0	0	1
Parkin	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
peroxisome proliferator activated receptor gamma	1	0	0	1
vitamin D (1,25- dihydroxyvitamin D3) receptor	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	1	0	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
Bloom syndrome protein isoform 1	1	0	0	1
cytochrome P450 2D6 isoform 1	1	0	0	1
peripheral myelin protein 22 isoform 1	1	0	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
tumor necrosis factor	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
cytochrome P450 2C19 precursor	1	0	0	1
cytochrome P450 2C9 precursor	1	0	0	1
D(1A) dopamine receptor	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	1	0	0	1
perilipin-5	0	1	0	1
vitamin D3 receptor isoform VDRA	1	0	0	1
perilipin-1	0	1	0	1
heat shock protein beta-1	1	0	0	1
mitogen-activated protein kinase 1	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
nuclear receptor ROR-gamma isoform 1	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
peripheral myelin protein 22	1	0	0	1
survival motor neuron protein isoform d	1	0	0	1
cytochrome P450 3A4 isoform 1	1	0	0	1
muscleblind-like protein 1 isoform 1	1	0	0	1
lamin isoform A-delta10	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
ATP-binding cassette sub-family C member 3	0	1	0	1
Multidrug resistance-associated protein 4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Bile salt export pump	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Potassium channel subfamily K member 2	0	0	1	1
Bile salt export pump	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Interferon beta	1	0	0	1
HLA class I histocompatibility antigen, B alpha chain	1	0	0	1
Integrin beta-3	1	0	0	1
Cytochrome P450 1A2	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	0	1
Muscarinic acetylcholine receptor M4	0	0	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Integrin alpha-IIb	1	0	0	1
Muscarinic acetylcholine receptor M5	0	0	0	1
Adenosine receptor A3	0	2	0	2
Muscarinic acetylcholine receptor M1	0	0	0	1
Cytochrome P450 2C9	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Phospholipase A2, membrane associated	0	0	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	1	0	0	1
Alpha-1B adrenergic receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	1	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	1	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	1	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	1	0	0	1
Muscarinic acetylcholine receptor M3	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	1	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	1	0	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	1	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	1	0	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	1	0	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A2a	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Alpha-1A adrenergic receptor	0	2	0	2
Histamine H2 receptor	1	0	0	1
Cytochrome P450 2J2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	1	0	0	1
Gamma-aminobutyric acid receptor subunit beta-3	1	0	0	1
Gamma-aminobutyric acid receptor subunit beta-2	1	0	0	1
Inositol monophosphatase 1	1	0	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Leukotriene B4 receptor 1	0	0	0	1
Myosin light chain kinase, smooth muscle	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Potassium channel subfamily K member 2	0	1	0	1
Beta-2 adrenergic receptor	0	0	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
GABA theta subunit	1	0	0	1
Inositol hexakisphosphate kinase 1	1	0	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
cytochrome P450 2C9, partial	1	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Research

Studies (29)

Protein Targets (215)

Adenomatoid Tumor

Synonyms(1)

Research Excerpts

Overview

Research

Studies (29)

Drugs Studied (8)

Protein Targets (215)