Target type: biologicalprocess
The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]
Nitrogen compound transport encompasses a diverse set of processes crucial for life, involving the movement of nitrogen-containing molecules across cellular membranes and within organisms. This intricate network of pathways facilitates nutrient uptake, waste removal, and the biosynthesis of essential biomolecules.
**1. Uptake and Assimilation:**
* **Nitrogen fixation:** The conversion of atmospheric nitrogen (N2) into usable forms like ammonia (NH3) by nitrogen-fixing microorganisms is a vital step in the nitrogen cycle. These organisms possess the enzyme nitrogenase, which catalyzes this energy-intensive reaction.
* **Nitrate (NO3-) uptake:** Plants and many microorganisms can absorb nitrate from the soil or water. Nitrate reductase enzymes convert nitrate into nitrite (NO2-), which is then further reduced to ammonia by nitrite reductase.
* **Ammonia (NH3) uptake:** Ammonia is readily absorbed by organisms and used for the synthesis of amino acids and other nitrogen-containing molecules.
**2. Intracellular Transport:**
* **Amino acid transport:** Amino acids are transported across cellular membranes through specific transporter proteins, ensuring their delivery to the appropriate compartments for protein synthesis and other metabolic processes.
* **Nitrogenous waste transport:** Excess nitrogenous waste products, such as urea and uric acid, need to be efficiently removed from the body. Specialized transporters facilitate their movement to the kidneys or other excretory organs.
**3. Intercellular Transport:**
* **Long-distance transport in plants:** In vascular plants, nitrogen compounds are transported through the xylem and phloem, ensuring their distribution from roots to shoots and other tissues.
* **Hormonal transport:** Some nitrogen-containing compounds act as hormones, regulating various physiological processes. Their transport throughout the body is essential for proper function.
**4. Extracellular Transport:**
* **Nitrogen cycling in ecosystems:** Decomposers break down organic matter, releasing nitrogen back into the environment, where it can be taken up by other organisms.
* **Nitrogen loss from ecosystems:** Certain processes, like denitrification, lead to the loss of nitrogen from ecosystems, often converting nitrate into nitrogen gas that escapes into the atmosphere.
In summary, nitrogen compound transport encompasses a wide range of mechanisms that ensure the efficient uptake, assimilation, and distribution of nitrogen-containing molecules, contributing to the fundamental processes of life.'
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Protein | Definition | Taxonomy |
---|---|---|
Sodium- and chloride-dependent GABA transporter 2 | A sodium- and chloride-dependent GABA transporter 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9NSD5] | Homo sapiens (human) |
Sodium- and chloride-dependent GABA transporter 2 | A sodium- and chloride-dependent GABA transporter 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9NSD5] | Homo sapiens (human) |
Sodium- and chloride-dependent creatine transporter 1 | A sodium- and chloride-dependent creatine transporter 1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P48029] | Homo sapiens (human) |
Sodium- and chloride-dependent taurine transporter | A sodium- and chloride-dependent taurine transporter that is encoded in the genome of human. [PRO:DNx, UniProtKB:P31641] | Homo sapiens (human) |
Compound | Definition | Classes | Roles |
---|---|---|---|
gamma-aminobutyric acid | gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4. gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. | amino acid zwitterion; gamma-amino acid; monocarboxylic acid | human metabolite; neurotransmitter; Saccharomyces cerevisiae metabolite; signalling molecule |
beta-alanine | amino acid zwitterion; beta-amino acid | agonist; fundamental metabolite; human metabolite; inhibitor; neurotransmitter | |
2,3-diaminopropionic acid | 3-aminoalanine : A diamino acid that is alanine in which one of the hydrogens of the methyl group is replaced by an amino group. | alanine derivative; amino acid zwitterion; beta-amino acid; diamino acid; non-proteinogenic alpha-amino acid | Escherichia coli metabolite |
creatine | glycine derivative; guanidines; zwitterion | geroprotector; human metabolite; mouse metabolite; neuroprotective agent; nutraceutical | |
taurine | amino sulfonic acid; zwitterion | antioxidant; Escherichia coli metabolite; glycine receptor agonist; human metabolite; mouse metabolite; nutrient; radical scavenger; Saccharomyces cerevisiae metabolite | |
guvacine | guvacine : A alpha,beta-unsaturated monocarboxylic acid that is nicotinic acid which has been hydrogenated at the 1-2 and 5-6 positions of the pyridine ring. guvacine: RN given refers to parent cpd | alpha,beta-unsaturated monocarboxylic acid; beta-amino acid; pyridine alkaloid; secondary amino compound; tetrahydropyridine | GABA reuptake inhibitor; plant metabolite |
nipecotic acid | nipecotic acid : A piperidinemonocarboxylic acid that is piperidine in which one of the hydrogens at position 3 is substituted by a carboxylic acid group. nipecotic acid: RN given refers to cpd without isomeric designation | beta-amino acid; piperidinemonocarboxylic acid | |
n-(1-benzyl-4-piperidinyl)-2,4-dichlorobenzamide | N-(1-benzyl-4-piperidinyl)-2,4-dichlorobenzamide: inhibits the betaine-GABA transporter 1; structure in first source | ||
2-ethoxy-N-[1-(phenylmethyl)-4-piperidinyl]benzamide | piperidines | ||
nnc 05-2090 | NNC 05-2090: structure given in first source | carbazoles | |
snap 5114 |