| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, JmjC domain-containing histone demethylation protein 3A | 2 | 0 | 0 | 2 |
| Luciferase | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 2 | 0 | 0 | 2 |
| TDP1 protein | 7 | 0 | 0 | 7 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| AR protein | 7 | 0 | 0 | 7 |
| aldehyde dehydrogenase 1 family, member A1 | 5 | 0 | 0 | 5 |
| glucocorticoid receptor [Homo sapiens] | 6 | 0 | 0 | 6 |
| estrogen nuclear receptor alpha | 7 | 0 | 0 | 7 |
| peroxisome proliferator activated receptor gamma | 4 | 0 | 0 | 4 |
| euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 6 | 0 | 0 | 6 |
| vitamin D3 receptor isoform VDRA | 3 | 0 | 0 | 3 |
| thyroid hormone receptor beta isoform 2 | 7 | 0 | 0 | 7 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
| eyes absent homolog 2 isoform a | 1 | 0 | 0 | 1 |
| DNA polymerase eta isoform 1 | 1 | 0 | 0 | 1 |
| geminin | 7 | 0 | 0 | 7 |
| peripheral myelin protein 22 | 3 | 0 | 0 | 3 |
| survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
| Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 3 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 3 | 0 | 3 |
| Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
| Cellular tumor antigen p53 | 6 | 0 | 0 | 6 |
| Rap guanine nucleotide exchange factor 4 | 1 | 0 | 0 | 1 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 3 | 0 | 0 | 3 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | 5 | 0 | 0 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | 4 | 0 | 0 | 4 |
| retinoid X nuclear receptor alpha | 4 | 0 | 0 | 4 |
| estrogen-related nuclear receptor alpha | 4 | 0 | 0 | 4 |
| pregnane X nuclear receptor | 4 | 0 | 0 | 4 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 3 | 0 | 0 | 3 |
| caspase-3 | 1 | 0 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 6 | 0 | 0 | 6 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Solute carrier organic anion transporter family member 2B1 | 0 | 0 | 0 | 1 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0 | 2 | 0 | 2 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Insulin receptor | 0 | 1 | 0 | 1 |
| Glutamate receptor 2 | 2 | 1 | 0 | 3 |
| Dipeptidyl peptidase 4 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0 | 1 | 0 | 1 |
| Histone deacetylase 1 | 0 | 1 | 0 | 1 |
| Histone deacetylase 2 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B3 | 0 | 0 | 0 | 1 |
| Histone deacetylase 6 | 0 | 1 | 0 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 2 | 0 | 2 |
| Solute carrier organic anion transporter family member 1B1 | 0 | 2 | 0 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| apical membrane antigen 1, AMA1 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 3 | 0 | 0 | 3 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 2 | 0 | 0 | 2 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Matrix metalloproteinase-9 | 0 | 1 | 0 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | 1 | 0 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
| corticotropin-releasing hormone receptor 2 | 0 | 1 | 1 | 2 |
| polyprotein | 1 | 0 | 0 | 1 |
| 67.9K protein | 3 | 0 | 0 | 3 |
| corticotropin releasing factor-binding protein | 0 | 1 | 1 | 2 |
| IDH1 | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 3 | 0 | 0 | 3 |
| glycogen synthase kinase-3 beta isoform 1 | 0 | 0 | 2 | 2 |
| urokinase-type plasminogen activator precursor | 3 | 0 | 0 | 3 |
| plasminogen precursor | 3 | 0 | 0 | 3 |
| urokinase plasminogen activator surface receptor precursor | 3 | 0 | 0 | 3 |
| 5'-nucleotidase | 0 | 1 | 0 | 1 |
| Adenosine receptor A3 | 0 | 1 | 0 | 1 |
| Adenosine deaminase | 0 | 0 | 0 | 2 |
| Chain A, Inosine-5'-Monophosphate Dehydrogenase 2 | 0 | 1 | 0 | 1 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| UDP-glucuronosyltransferase 1A9 | 0 | 0 | 0 | 1 |
| Inosine-5'-monophosphate dehydrogenase 2 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Glutamate receptor 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor 3 | 0 | 1 | 0 | 1 |
| Glutamate receptor 4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Inosine-5'-monophosphate dehydrogenase 1 | 0 | 2 | 0 | 2 |
| UDP-glucuronosyltransferase 1A1 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| Peroxisome proliferator-activated receptor gamma | 0 | 0 | 1 | 1 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Inosine-5'-monophosphate dehydrogenase | 0 | 1 | 0 | 2 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| UDP-glucuronosyltransferase 1A7 | 0 | 0 | 0 | 1 |
| UDP-glucuronosyltransferase 1A10 | 0 | 0 | 0 | 1 |
| UDP-glucuronosyltransferase 1A8 | 0 | 0 | 0 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| Glucocorticoid receptor | 0 | 2 | 1 | 3 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 2B7 | 0 | 0 | 0 | 1 |
| Cytochrome P450 3A5 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 1A4 | 0 | 0 | 0 | 1 |
| Serine/threonine-protein kinase mTOR | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | 0 | 2 | 1 | 3 |
| Peptidyl-prolyl cis-trans isomerase FKBP1B | 0 | 0 | 1 | 1 |
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 0 | 1 | 0 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP5 | 0 | 1 | 0 | 1 |
| Splicing factor 3B subunit 3 | 0 | 1 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| Thymidine kinase, cytosolic | 0 | 0 | 0 | 1 |
| Dipeptidyl peptidase 4 | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 0 | 1 | 1 |
| Adenosylhomocysteinase | 0 | 1 | 0 | 1 |
| RNA-directed RNA polymerase | 0 | 1 | 1 | 2 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |