| Assay ID | Title | Year | Journal | Article |
|---|
| AID293618 | Cytotoxicity against Vero cells | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5
| Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study. |
| AID252970 | Percent cell proliferation of human leukemia cell line HL-60 at 1*E-5 M | 2005 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 15, Issue:13
| Cell differentiation inducers derived from thalidomide. |
| AID293621 | Apoptotic activity in human blood neutrophils after 72 hrs | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5
| Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study. |
| AID251888 | Cell growth-inhibitory activity toward human leukemia cell line HL60 at 6 uM concentration | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Tubulin-polymerization inhibitors derived from thalidomide. |
| AID56226 | Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell line | 1999 | Bioorganic & medicinal chemistry letters, Feb-22, Volume: 9, Issue:4
| Nonpeptide small-molecular inhibitors of dipeptidyl peptidase IV: N-phenylphthalimide analogs. |
| AID251887 | Cell growth-inhibitory activity toward human leukemia cell line HL60 at 3 uM concentration | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Tubulin-polymerization inhibitors derived from thalidomide. |
| AID257636 | Inhibitory activity in HUVEC tube formation assay at 100 uM | 2005 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 15, Issue:24
| Angiogenesis inhibitors derived from thalidomide. |
| AID293622 | Partition coefficient, log P of the compound | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5
| Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study. |
| AID81275 | Tumor necrosis factor-alpha production in human leukemia cell line (HL-60) stimulated with 10 nM 12-O-tetradecanoylphorbol 13-acetate (TPA) at 30 uMolar. | 1997 | Journal of medicinal chemistry, Aug-29, Volume: 40, Issue:18
| Novel biological response modifiers: phthalimides with tumor necrosis factor-alpha production-regulating activity. |
| AID38364 | Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell line | 1999 | Bioorganic & medicinal chemistry letters, Feb-22, Volume: 9, Issue:4
| Nonpeptide small-molecular inhibitors of dipeptidyl peptidase IV: N-phenylphthalimide analogs. |
| AID309667 | Inhibition of IL-1-alpha-induced NF-kappaB activation in HeLa cells assessed as blocking of p50/p65 nuclear translocation | 2007 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 17, Issue:21
| Inhibitors of NF-kappaB derived from thalidomide. |
| AID293620 | Apoptotic activity in human blood neutrophils after 48 hrs | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5
| Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study. |
| AID293619 | Apoptotic activity in human blood neutrophils after 24 hrs | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5
| Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study. |
| AID218272 | In vitro cytotoxicity against human embryonic lung fibroblast WI-38 cells. | 1997 | Journal of medicinal chemistry, Aug-29, Volume: 40, Issue:18
| Novel biological response modifiers: phthalimides with tumor necrosis factor-alpha production-regulating activity. |
| AID257637 | Inhibitory activity in HUVEC tube formation assay at 30 uM | 2005 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 15, Issue:24
| Angiogenesis inhibitors derived from thalidomide. |
| AID38377 | Inhibitory activity against aminopeptidase N assayed by the L-Ala-MCA method. | 1998 | Journal of medicinal chemistry, Jan-29, Volume: 41, Issue:3
| Novel potent nonpeptide aminopeptidase N inhibitors with a cyclic imide skeleton. |
| AID219416 | Cytotoxicity in human embryonic lung flbroblast Wl-38 cells using WST-1 viability assay | 1999 | Bioorganic & medicinal chemistry letters, Feb-22, Volume: 9, Issue:4
| Nonpeptide small-molecular inhibitors of dipeptidyl peptidase IV: N-phenylphthalimide analogs. |
| AID251661 | Inhibitory activity against tubulin polymerization at 20 uM | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Tubulin-polymerization inhibitors derived from thalidomide. |
| AID1057531 | Antiproliferative activity against human DU145 cells assessed as growth inhibition by MTS assay | 2013 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 23, Issue:24
| Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action. |
| AID257638 | Inhibitory activity in HUVEC tube formation assay at 10 uM | 2005 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 15, Issue:24
| Angiogenesis inhibitors derived from thalidomide. |
| AID270729 | Inhibition of tubulin polymerization in porcine brain at 20 uM | 2006 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 16, Issue:18
| Tubulin polymerization inhibitors with a fluorinated phthalimide skeleton derived from thalidomide. |
| AID252627 | NBT positivity against human leukemia cell line HL-60 at 1*E-5 M | 2005 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 15, Issue:13
| Cell differentiation inducers derived from thalidomide. |
| AID1057532 | Antiproliferative activity against human PC3 cells assessed as growth inhibition by MTS assay | 2013 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 23, Issue:24
| Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action. |
| AID81272 | Tumor necrosis factor-alpha production in human leukemia cell line (HL-60) stimulated with 50 nM okadaic acid (OA), at 30 uMolar. | 1997 | Journal of medicinal chemistry, Aug-29, Volume: 40, Issue:18
| Novel biological response modifiers: phthalimides with tumor necrosis factor-alpha production-regulating activity. |
| AID251886 | Cell growth-inhibitory activity toward human leukemia cell line HL60 at 10 uM concentration | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2
| Tubulin-polymerization inhibitors derived from thalidomide. |
| AID1057530 | Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition by MTS assay | 2013 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 23, Issue:24
| Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |