Page last updated: 2024-12-06

dithiadene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

dithiadene: minor descriptor (75-85); on-line & Index Medicus search DIBENZOTHIEPINS (69-74) & BENZOTHIEPINS (75-85); RN given refers to parent cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

dithiadene : An organic heterotricyclic compound that is 4,9-dihydrothieno[2,3-c][2]benzothiepine substituted by a 3-(dimethylamino)propylidene group at position 4. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID6436111
CHEBI ID167625
MeSH IDM0262882

Synonyms (23)

Synonym
n,n-dimethyl-3-(5h-thieno[2,3-c][2]benzothiepin-10-ylidene)propan-1-amine
n,n-dimethyl-3-thieno[2,3-c][2]benzothiepin-4(9h)-ylidenepropylamine
CHEBI:167625
n,n-dimethyl-3-(thieno[2,3-c][2]benzothiepin-4(9h)-ylidene)propan-1-amine
dithiaden
bisulepin
dithiadene
AKOS005065427
(3e)-n,n-dimethyl-3-(5h-thieno[2,3-c][2]benzothiepin-10-ylidene)propan-1-amine
n,n-dimethyl-3-thieno(2,3-c)(2)benzothiepin-4(9h)-ylidenepropylamine
4-(3-dimethylaminopropylidene)-4,9-dihydrobenzo(e)thieno(2,3-b)thiepin
42504-83-6
bisulepin [mart.]
bisulepin [who-dd]
1-propanamine, n,n-dimethyl-3-thieno(2,3-c)(2)benzothiepin-4(9h)-ylidene-, (e)-
thieno(2,3-c)(2)benzothiepin-.delta.4(9h),.gamma.-propylamine, n,n-dimethyl-
595726R32U ,
1-propanamine, n,n-dimethyl-3-thieno(2,3-c)(2)benzothiepin-4(9h)-ylidene-
Q4918616
thieno(2,3-c)(2)benzothiepin-delta4(9h),gamma-propylamine, n,n-dimethyl-
unii-595726r32u
DTXSID301336166
(e)-n,n-dimethyl-3-thieno[2,3-c][2]benzothiepin-4(9h)-ylidene-1-propanamine

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" In contrast to dithiaden, dithiadenoxide exerts a demonstrable inhibitory action as much as the subtoxic or sublethal dosage in experiments in mice and rats."( [Pharmacologic profile of dithiadenoxide, a potential non-sedating H1-antihistaminic].
Blehová, H; Metys, J, 1992
)
0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
dithiadeneAn organic heterotricyclic compound that is 4,9-dihydrothieno[2,3-c][2]benzothiepine substituted by a 3-(dimethylamino)propylidene group at position 4.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (19)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's8 (42.11)18.2507
2000's11 (57.89)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other19 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]