Page last updated: 2024-09-27

5-hydroxy-2'-deoxycytidine

Description

5-hydroxy-2'-deoxycytidine: a major oxidation product of 2'-deoxycytidine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID477413
CHEMBL ID217849
SCHEMBL ID529289
MeSH IDM0200081

Synonyms (26)

Synonym
5-ohdc
5-hydroxydeoxycytidine'
4-amino-5-hydroxy-1-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
5-hydroxydeoxycytidine
52278-77-0
5-oh-dc
cytidine, 2'-deoxy-5-hydroxy-
5-hydroxy-2'-deoxycytidine
2'-deoxy-5-hydroxycytidine
CHEMBL217849
4-amino-5-hydroxy-1-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
unii-6jhe7fc4bx
oh-5-dc
ccris 8238
6jhe7fc4bx ,
cytidine,2'-deoxy-5-hydroxy-
BRD-K28271329-001-01-2
SCHEMBL529289
CKZJTNZSBMVFSU-UBKIQSJTSA-N
4-amino-5-hydroxy-1-((2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1h)-one
mfcd01937860
1-(2-deoxypentofuranosyl)-4-imino-1,4-dihydropyrimidine-2,5-diol
DTXSID00966652
Q27265006
4-amino-5-hydroxy-1-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
2'-deoxy-5-hydroxy-cytidine

Bioassays (3)

Assay IDTitleYearJournalArticle
AID273213Antiviral activity against coxsackievirus B3 in HeLa S3 cells assessed as reduction in viral titer2006Journal of medicinal chemistry, Oct-19, Volume: 49, Issue:21
Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.
AID273212Antiviral activity against poliovirus in HeLa S3 cells assessed as reduction in viral titer2006Journal of medicinal chemistry, Oct-19, Volume: 49, Issue:21
Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.
AID273211Viability of human HeLa S3 cells2006Journal of medicinal chemistry, Oct-19, Volume: 49, Issue:21
Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (21)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's8 (38.10)18.2507
2000's9 (42.86)29.6817
2010's4 (19.05)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other21 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]