Compounds > 1-phenyl-5-mercaptotetrazole
Page last updated: 2024-09-28

1-phenyl-5-mercaptotetrazole

Description

1-phenyl-5-mercaptotetrazole: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID690730
CHEMBL ID226652
CHEBI ID79916
SCHEMBL ID55213
MeSH IDM0085538

Synonyms (77)

Synonym
nsc-44916
nsc44916
1-phenyltetrazole-5-thiol
5-mercapto-1-phenyltetrazol
1h-tetrazole-5-thiol, 1-phenyl-
5h-tetrazole-5-thione,2-dihydro-1-phenyl-
2-tetrazoline-5-thione, 1-phenyl-
phenylmercaptotetrazole
mercaptophenyltetrazole
5-mercapto-1-phenyltetrazole
nsc24018
1-phenyl-5-mercaptotetrazole
1-phenyl-5-mercapto-tetrazol
1-phenyl-5-tetrazolethione
wln: t5nnnnj ar& esh
1-phenyltetrazole-thiol
86-93-1
nsc-24018
1-phenyl-5-mercapto-1,3,4-tetrazole
1-phenyltetrazoline-5-thione
nsc-67819
nsc67819
5-mercapto-1-phenyl-1,2,3,4-tetrazole
1ph5shtetrazol
STK292840
1-phenyl-1h-tetrazole-5-thiol
1-phenyl-1h-tetrazole-5-thiol, 98%
5-mercapto-1-phenyl-1h-tetrazole
nsc 24018
einecs 201-710-5
1-phenyl-5-mercapto-1,2,3,4-tetrazole
5h-tetrazole-5-thione, 1,2-dihydro-1-phenyl-
AC-10636
inchi=1/c7h6n4s/c12-7-8-9-10-11(7)6-4-2-1-3-5-6/h1-5h,(h,8,10,12)
ggzhvnzhfycsev-uhfffaoysa-
1-phenyl-2h-tetrazole-5-thione
AKOS000294827
chebi:79916 ,
CHEMBL226652
P0640
1-phenyl-5-mercapto-1h-tetrazole
AKOS000119154
1-phenyl-1,2,3,4-tetraazole-5-thiol
1pi3bd9u68 ,
unii-1pi3bd9u68
F1324-0059
FT-0608251
FT-0608250
PS-4593
1-phenyl-1h-1,2,3,4-tetrazole-5-thiol
AM90368
SCHEMBL55213
5-mercapto-l-phenyl-1h-tetrazole
1-phenyl-5-thioxo-1,2,3,4-tetrazoline
1-phenyl-1h-tetrazol-5-thiol
DTXSID1052589
1-phenyltetrazolethiol
1,2,3,4-tetrazole-5-thiol, 1-phenyl-
W-104051
1-phenyl-5-thio-1h-tetrazole
STR04238
1-phenyl-2-tetrazoline-5-thione
1,2-dihydro-1-phenyl-5h-tetrazole-5-thione
1-phenyl-1,2-tetrazoline-5-thione
F0264-0010
1-phenyl-1h-tetrazole-5-thiol, for spectrophotometric det. of pd, for the determination of bi, >=97.0%
sr-01000389024
SR-01000389024-1
1-phenyl-1,4-dihydro-5h-tetrazole-5-thione
BCP05577
Q27149080
F15412
1-phenyltetrazole-5-thione
1-phenyl-1,2-dihydro-5h-tetrazole-5-thione
CS-0067555
EN300-17719
PD148028

Drug Classes (1)

ClassDescription
tetrazolesAn azole in which the five-membered heterocyclic aromatic skeleton contains four N atoms and one C atom.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2IC50 (µMol)2.36000.00022.45859.9600AID1640021
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Molecular Functions (10)

Processvia Protein(s)Taxonomy
3'-5'-RNA exonuclease activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
RNA-dependent RNA polymerase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
cysteine-type endopeptidase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
mRNA 5'-cap (guanine-N7-)-methyltransferase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
mRNA (nucleoside-2'-O-)-methyltransferase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
mRNA guanylyltransferase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
RNA endonuclease activity, producing 3'-phosphomonoestersReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
ISG15-specific peptidase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
5'-3' RNA helicase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
protein guanylyltransferase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (1)

Processvia Protein(s)Taxonomy
double membrane vesicle viral factory outer membraneReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (30)

Assay IDTitleYearJournalArticle
AID287810Antimicrobial activity against Mycobacterium tuberculosis My 331/88 after 21 days2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID461007Selectivity index, ratio of CTD50 for MDCK cells to EC50 for Influenza A virus (A/Puerto Rico/8/34(H1N1))2010Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2
Synthesis and anti-viral activity of azolo-adamantanes against influenza A virus.
AID287817Antimicrobial activity against Mycobacterium kansasii My 6509/96 after 14 days2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID287835Antiproliferative activity against mouse L929 cells after 72 hrs2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID287836Antiproliferative activity against human K562 cells after 72 hrs2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID287811Antimicrobial activity against Mycobacterium avium My 330/88 after 14 days2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID1243324Antimicrobial activity against Proteus mirabilis after 24 hrs by well-diffusion assay2015Bioorganic & medicinal chemistry letters, Sep-15, Volume: 25, Issue:18
Synthesis, antibacterial and QSAR evaluation of 5-oxo and 5-thio derivatives of 1,4-disubstituted tetrazoles.
AID1612601Antibacterial activity against Mycobacterium kansasii CNCTC My 235/802019European journal of medicinal chemistry, Feb-01, Volume: 163Recent advances of tetrazole derivatives as potential anti-tubercular and anti-malarial agents.
AID1243319Antimicrobial activity against Staphylococcus aureus after 24 hrs by well-diffusion assay2015Bioorganic & medicinal chemistry letters, Sep-15, Volume: 25, Issue:18
Synthesis, antibacterial and QSAR evaluation of 5-oxo and 5-thio derivatives of 1,4-disubstituted tetrazoles.
AID287809Antimicrobial activity against Mycobacterium tuberculosis My 331/88 after 14 days2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID287816Antimicrobial activity against Mycobacterium kansasii My 6509/96 after 7 days2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID287837Cytotoxicity against human HeLa cells after 72 hrs2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID1612603Antibacterial activity against Mycobacterium kansasii isolate 6509/962019European journal of medicinal chemistry, Feb-01, Volume: 163Recent advances of tetrazole derivatives as potential anti-tubercular and anti-malarial agents.
AID287814Antimicrobial activity against Mycobacterium kansasii My 235/80 after 14 days2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID1243320Antimicrobial activity against Streptococcus spp. after 24 hrs by well-diffusion assay2015Bioorganic & medicinal chemistry letters, Sep-15, Volume: 25, Issue:18
Synthesis, antibacterial and QSAR evaluation of 5-oxo and 5-thio derivatives of 1,4-disubstituted tetrazoles.
AID287815Antimicrobial activity against Mycobacterium kansasii My 235/80 after 21 days2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID1243327Antimicrobial activity against Staphylococcus aureus after 24 hrs by microbroth dilution assay2015Bioorganic & medicinal chemistry letters, Sep-15, Volume: 25, Issue:18
Synthesis, antibacterial and QSAR evaluation of 5-oxo and 5-thio derivatives of 1,4-disubstituted tetrazoles.
AID287818Antimicrobial activity against Mycobacterium kansasii My 6509/96 after 21 days2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID1243326Antimicrobial activity against Escherichia coli after 24 hrs by microbroth dilution assay2015Bioorganic & medicinal chemistry letters, Sep-15, Volume: 25, Issue:18
Synthesis, antibacterial and QSAR evaluation of 5-oxo and 5-thio derivatives of 1,4-disubstituted tetrazoles.
AID461006Antiviral activity against Influenza A virus (A/Puerto Rico/8/34(H1N1)) infected in MDCK cells assessed as virus yield after 48 hrs end-point dilution method2010Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2
Synthesis and anti-viral activity of azolo-adamantanes against influenza A virus.
AID287812Antimicrobial activity against Mycobacterium avium My 330/88 after 21 days2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID287813Antimicrobial activity against Mycobacterium kansasii My 235/80 after 7 days2007Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
AID1243323Antimicrobial activity against Klebsiella pneumoniae after 24 hrs by well-diffusion assay2015Bioorganic & medicinal chemistry letters, Sep-15, Volume: 25, Issue:18
Synthesis, antibacterial and QSAR evaluation of 5-oxo and 5-thio derivatives of 1,4-disubstituted tetrazoles.
AID1243321Antimicrobial activity against Bacillus subtilis after 24 hrs by well-diffusion assay2015Bioorganic & medicinal chemistry letters, Sep-15, Volume: 25, Issue:18
Synthesis, antibacterial and QSAR evaluation of 5-oxo and 5-thio derivatives of 1,4-disubstituted tetrazoles.
AID1243325Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by well-diffusion assay2015Bioorganic & medicinal chemistry letters, Sep-15, Volume: 25, Issue:18
Synthesis, antibacterial and QSAR evaluation of 5-oxo and 5-thio derivatives of 1,4-disubstituted tetrazoles.
AID1612602Antibacterial activity against Mycobacterium avium CNCTC My 330/882019European journal of medicinal chemistry, Feb-01, Volume: 163Recent advances of tetrazole derivatives as potential anti-tubercular and anti-malarial agents.
AID461005Cytotoxicity against MDCK cells after 48 hrs by MTT assay2010Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2
Synthesis and anti-viral activity of azolo-adamantanes against influenza A virus.
AID1243322Antimicrobial activity against Escherichia coli after 24 hrs by well-diffusion assay2015Bioorganic & medicinal chemistry letters, Sep-15, Volume: 25, Issue:18
Synthesis, antibacterial and QSAR evaluation of 5-oxo and 5-thio derivatives of 1,4-disubstituted tetrazoles.
AID1612600Antibacterial activity against Mycobacterium tuberculosis CNCTC My 331/882019European journal of medicinal chemistry, Feb-01, Volume: 163Recent advances of tetrazole derivatives as potential anti-tubercular and anti-malarial agents.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (10.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (10.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (90.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
ciprofloxacin[no description available]medium10aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
fluconazole[no description available]medium10conazole antifungal drug;
difluorobenzene;
tertiary alcohol;
triazole antifungal drug		environmental contaminant;
P450 inhibitor;
xenobiotic
isoniazid[no description available]medium20carbohydrazideantitubercular agent;
drug allergen
amphotericin b[no description available]medium10antibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic		antiamoebic agent;
antiprotozoal drug;
bacterial metabolite
rimantadine[no description available]medium10alkylamine
ethambutol[no description available]medium10ethanolamines;
ethylenediamine derivative		antitubercular agent;
environmental contaminant;
xenobiotic
artemisinin[no description available]medium10organic peroxide;
sesquiterpene lactone		antimalarial;
plant metabolite
artenimol[no description available]medium10
artesunate[no description available]medium10artemisinin derivative;
cyclic acetal;
dicarboxylic acid monoester;
hemisuccinate;
semisynthetic derivative;
sesquiterpenoid		antimalarial;
antineoplastic agent;
ferroptosis inducer
rifampin[no description available]medium10cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
1h-tetrazole[no description available]medium10one-carbon compound;
tetrazole
silicon[no description available]medium10carbon group element atom;
metalloid atom;
nonmetal atom
catechol[no description available]medium10catecholsallelochemical;
genotoxin;
plant metabolite
hydroquinone[no description available]medium10benzenediol;
hydroquinones		antioxidant;
carcinogenic agent;
cofactor;
Escherichia coli metabolite;
human xenobiotic metabolite;
mouse metabolite;
skin lightening agent
betaine[no description available]medium10amino-acid betaine;
glycine derivative		fundamental metabolite
2-methylthiazoline[no description available]medium10thiazoles
thiazoles[no description available]medium101,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
benzoxazoles[no description available]medium101,3-benzoxazoles;
mancude organic heterobicyclic parent
azides[no description available]medium10pseudohalide anionmitochondrial respiratory-chain inhibitor
acetonitrile[no description available]medium10aliphatic nitrile;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent
acitazanolast[no description available]low00tetrazoles
azosemide[no description available]low00monochlorobenzenes;
sulfonamide;
tetrazoles;
thiophenes		loop diuretic
cilostazol[no description available]low00lactam;
tetrazoles		anticoagulant;
bronchodilator agent;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
fibrin modulating drug;
neuroprotective agent;
platelet aggregation inhibitor;
vasodilator agent
ly 171883[no description available]low00acetophenones;
aromatic ether;
phenols;
tetrazoles		anti-asthmatic drug;
leukotriene antagonist
cefazolin[no description available]low00beta-lactam antibiotic allergen;
cephalosporin;
tetrazoles;
thiadiazoles		antibacterial drug
cefminox[no description available]low00cephamycin;
tetrazoles
gr 117289[no description available]low001-benzofurans;
biaryl;
imidazolyl carboxylic acid;
monocarboxylic acid;
organobromine compound;
organochlorine compound;
tetrazoles		angiotensin receptor antagonist;
antihypertensive agent
a 8947[no description available]low00aromatic ether;
biaryl;
N-sulfonylurea;
pyrazole pesticide;
tetrazoles		EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide
forasartan[no description available]low00benzenes;
pyridines;
tetrazoles;
triazoles		angiotensin receptor antagonist;
antihypertensive agent
5-(4-methylphenyl)-2H-tetrazole[no description available]low00tetrazoles
5-(3,4-dimethoxyphenyl)-2H-tetrazole[no description available]low00tetrazoles
2-[5-(4-butoxyphenyl)-2-tetrazolyl]-N-(2-furanylmethyl)acetamide[no description available]low00tetrazoles
1-[2,5-diethoxy-4-(1-tetrazolyl)phenyl]sulfonyl-4-(4-fluorophenyl)-3,6-dihydro-2H-pyridine[no description available]low00tetrazoles
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[[1-(3,4-dimethoxyphenyl)-5-tetrazolyl]thio]acetamide[no description available]low00tetrazoles
1-(4-chlorophenyl)sulfonyl-N-[3-methoxy-4-(1-tetrazolyl)phenyl]-4-piperidinecarboxamide[no description available]low00tetrazoles
3-[5-(4-ethylphenyl)-2-tetrazolyl]propanoic acid methyl ester[no description available]low00tetrazoles
N,N-bis(but-2-ynyl)-3-methoxy-4-(1-tetrazolyl)benzenesulfonamide[no description available]low00tetrazoles
2,5-diethoxy-N-[2-(2-methylphenyl)ethyl]-4-(1-tetrazolyl)benzenesulfonamide[no description available]low00tetrazoles
2-[cyclohexyl-[2-[5-(3,4-dimethoxyphenyl)-2-tetrazolyl]-1-oxoethyl]amino]-N-cyclopentylpropanamide[no description available]low00tetrazoles
N-(3-bicyclo[2.2.1]heptanyl)-2-[5-(4-chlorophenyl)-2-tetrazolyl]acetamide[no description available]low00tetrazoles
1-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-2-[5-[4-(dimethylamino)phenyl]-2-tetrazolyl]ethanone[no description available]low00dibenzoazepine;
tetrazoles
N-(3-methoxyphenyl)-1-[4-(1-tetrazolyl)phenyl]sulfonyl-3-piperidinecarboxamide[no description available]low00tetrazoles
2-[5-(3,4-diethoxyphenyl)-2-tetrazolyl]-N-(3-methoxyphenyl)acetamide[no description available]low00tetrazoles
N-cyclopentyl-2-[[1-(2-methoxyphenyl)-5-tetrazolyl]thio]acetamide[no description available]low00tetrazoles
5-(4-propan-2-ylphenyl)-2H-tetrazole[no description available]low00tetrazoles
1-(2-methyl-6-propan-2-ylphenyl)-5-phenyltetrazole[no description available]low00tetrazoles
N-(4-acetamidophenyl)-2-[[1-(4-ethylphenyl)-5-tetrazolyl]thio]acetamide[no description available]low00tetrazoles
2-[5-(2-fluorophenyl)-2-tetrazolyl]-N-[2-oxo-2-[(phenylmethyl)amino]ethyl]-N-(5,6,7,8-tetrahydronaphthalen-1-yl)acetamide[no description available]low00tetrazoles
N2-phenyl-6-[[(1-phenyl-5-tetrazolyl)thio]methyl]-1,3,5-triazine-2,4-diamine[no description available]low00tetrazoles
3-[1-(4-chlorophenyl)-5-tetrazolyl]-1-methyl-4-quinolinone[no description available]low00tetrazoles
3-(2-phenyl-5-tetrazolyl)pyridine[no description available]low00tetrazoles
N2,N2-dimethyl-6-[[(1-phenyl-5-tetrazolyl)thio]methyl]-1,3,5-triazine-2,4-diamine[no description available]low00tetrazoles
N-(2-methoxyphenyl)-2-[5-[2-[(4-methoxyphenyl)sulfonylamino]phenyl]-2-tetrazolyl]acetamide[no description available]low00tetrazoles
5-[(2-chlorophenyl)methylsulfonyl]-1-(2,6-dimethylphenyl)tetrazole[no description available]low00tetrazoles
5-[2-(2-methoxyphenoxy)ethylthio]-1-(4-methylphenyl)tetrazole[no description available]low00tetrazoles
7-[[[1-(2-methylphenyl)-5-tetrazolyl]thio]methyl]-5-thiazolo[3,2-a]pyrimidinone[no description available]low00tetrazoles
2-[4-[(1-phenyl-5-tetrazolyl)oxy]phenyl]-1,3,4-oxadiazole[no description available]low00tetrazoles
N-[2-(1-cyclohexenyl)ethyl]-1-phenyl-5-tetrazolamine[no description available]low00tetrazoles
2-[[[1-(2-methoxy-5-methylphenyl)-5-tetrazolyl]thio]methyl]-1,3-benzothiazole[no description available]low00tetrazoles
2,4-dimethyl-5-[2-[[1-(4-methylphenyl)-5-tetrazolyl]thio]-1-oxoethyl]-1H-pyrrole-3-carboxylic acid ethyl ester[no description available]low00tetrazoles
1-[[2-[5-[3,5-bis(trifluoromethyl)phenyl]-2-tetrazolyl]-1-oxoethyl]amino]-3-(4-chlorophenyl)thiourea[no description available]low00tetrazoles
3-[1-(3,5-dichlorophenyl)-5-tetrazolyl]-5-methylisoxazole[no description available]low00tetrazoles
1-(2-benzofuranyl)-2-[[1-(2,4,6-trimethylphenyl)-5-tetrazolyl]thio]ethanone[no description available]low00tetrazoles
4-[2,2-bis(1-phenyl-5-tetrazolyl)ethenyl]-N,N-dimethylaniline[no description available]low00tetrazoles
3-[(1-phenyl-5-tetrazolyl)thio]-2-oxolanone[no description available]low00tetrazoles
N-(5-chloro-2-pyridinyl)-2-[(1-phenyl-5-tetrazolyl)thio]propanamide[no description available]low00tetrazoles
1-(2-methoxy-5-methylphenyl)-5-(2-oxanylmethylthio)tetrazole[no description available]low00tetrazoles
5-[4-(1-imidazolyl)phenoxy]-1-phenyltetrazole[no description available]low00tetrazoles
N-(2-oxolanylmethyl)-3-(1-tetrazolyl)benzamide[no description available]low00tetrazoles
N'-[2-(4-methylphenoxy)-1-oxoethyl]-2-(5-phenyl-2-tetrazolyl)acetohydrazide[no description available]low00tetrazoles
N-cyclopentyl-2-[[2-[5-(4-fluorophenyl)-2-tetrazolyl]-1-oxoethyl]-(2-furanylmethyl)amino]hexanamide[no description available]low00tetrazoles
N-tert-butyl-2-(N-[2-[5-(4-fluorophenyl)-2-tetrazolyl]-1-oxoethyl]-3-hydroxyanilino)-2-(1H-indol-3-yl)acetamide[no description available]low00tetrazoles
N-cyclohexyl-2-[3-methoxy-N-(1-oxo-2-thiophen-2-ylethyl)-4-(1-tetrazolyl)anilino]-2-(4-methylphenyl)acetamide[no description available]low00tetrazoles
2-[2-[[2-[[1-(2,4-dimethylphenyl)-5-tetrazolyl]thio]-1-oxoethyl]amino]-4-thiazolyl]acetic acid ethyl ester[no description available]low00tetrazoles
cefteram pivoxil[no description available]low001,3-thiazoles;
cephams;
oxime O-ether;
pivaloyloxymethyl ester;
tetrazoles
tedizolid[no description available]low00carbamate ester;
organofluorine compound;
oxazolidinone;
primary alcohol;
pyridines;
tetrazoles		antimicrobial agent;
drug metabolite;
protein synthesis inhibitor
tedizolid phosphate[no description available]low00carbamate ester;
organofluorine compound;
oxazolidinone;
phosphate monoester;
pyridines;
tetrazoles		antimicrobial agent;
prodrug;
protein synthesis inhibitor
3-[2-(4-fluorophenyl)-5-tetrazolyl]-2-methoxypyridine[no description available]low00tetrazoles
4-[2-(4-fluorophenyl)-5-tetrazolyl]quinoline[no description available]low00tetrazoles
2-chloro-3-[2-(4-methylphenyl)-5-tetrazolyl]pyridine[no description available]low00tetrazoles
3-[2-(4-methylphenyl)-5-tetrazolyl]quinoline[no description available]low00tetrazoles
2-chloro-3-[2-(3,4-dichlorophenyl)-5-tetrazolyl]pyridine[no description available]low00tetrazoles
ConditionIndicatedRelationship StrengthStudiesTrials
Anasarca0low10
Anemia, Fanconi0low10
Dropsy0low10
Edema0low10
Fanconi Anemia0low10
Fanconi Hypoplastic Anemia0low10
Fanconi Pancytopenia0low10
Fanconi Panmyelopathy0low10
Fanconi's Anemia0low10
Hydrops0low10

Research Highlights

Bioavailability (1)

ArticleYear
Recent advances of tetrazole derivatives as potential anti-tubercular and anti-malarial agents.
European journal of medicinal chemistry, Feb-01, Volume: 163		2019
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]