Page last updated: 2024-12-10
n,o-didesmethylvenlafaxine
Description
N,O-didesmethylvenlafaxine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
N,O-didesmethylvenlafaxine : A secondary amino compound that is N-methylethanamine substituted by a 1-hydroxycyclohexyl and a 4-hydroxyphenyl group at position 1. It is a metabolite of the drug venlafaxine. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 3451347 |
| CHEBI ID | 83529 |
| SCHEMBL ID | 902641 |
| MeSH ID | M0397708 |
Synonyms (26)
| Synonym |
|---|
| 4-[1-(1-hydroxycyclohexyl)-2-(methylamino)ethyl]phenol |
| FT-0666708 |
| dyw3w9739y , |
| n,o-didesmethylvenlafaxine |
| unii-dyw3w9739y |
| 135308-74-6 |
| rac n,o-didesmethyl venlafaxine |
| 4-(1-(1-hydroxycyclohexyl)-2-(methylamino)ethyl)phenol |
| n,o-didesvenlafaxine |
| phenol, 4-(1-(1-hydroxycyclohexyl)-2-(methylamino)ethyl)- |
| d,l n,o-didesmethyl venlafaxine |
| n-desmethyldesvenlafaxine |
| CHEBI:83529 |
| SCHEMBL902641 |
| wy 46689 |
| didesmethyl venlafaxine, n,o- |
| AKOS030255682 |
| J-006679 |
| nve_250.1804_10.8 |
| n,o-didesmethyl venlafaxine |
| DTXSID10891441 |
| Q27156920 |
| d,l n,o-didesmethylvenlafaxine |
| BCP33779 |
| d,l n,o-didesmethyl venlafaxine;4-(1-(1-hydroxycyclohexyl)-2-(methylamino)ethyl)phenol |
| E98736 |
Roles (2)
| Role | Description |
|---|
| marine xenobiotic metabolite | Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms. |
| drug metabolite | null |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (3)
| Class | Description |
|---|
| cyclohexanols | An alcohol in which one or more hydroxy groups are attached to a cyclohexane skeleton. |
| phenols | Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring. |
| secondary amino compound | A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.63
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.63 (24.57) | | Research Supply Index | 1.79 (2.92) | | Research Growth Index | 4.42 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |