bb3497 has been researched along with isoniazid in 3 studies
| Studies (bb3497) | Trials (bb3497) | Recent Studies (post-2010) (bb3497) | Studies (isoniazid) | Trials (isoniazid) | Recent Studies (post-2010) (isoniazid) |
|---|---|---|---|---|---|
| 13 | 0 | 2 | 21,815 | 960 | 4,493 |
| Protein | Taxonomy | bb3497 (IC50) | isoniazid (IC50) |
|---|---|---|---|
| Myeloperoxidase | Homo sapiens (human) | 4.85 | |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium tuberculosis H37Rv | 8.29 | |
| Putative FAD-containing monooxygenase MymA | Mycobacterium tuberculosis H37Rv | 4.9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Canaan, S; Cavalier, JF; Magrioti, V; Mallick, I; Mavrikaki, V; Pagonis, A; Poncin, I | 1 |
| Kanwar, AJ; Khuller, GK; Sharma, A; Sharma, S | 2 |
3 other study(ies) available for bb3497 and isoniazid
| Article | Year |
|---|---|
Design, synthesis and antibacterial activity against pathogenic mycobacteria of conjugated hydroxamic acids, hydrazides and O-alkyl/O-acyl protected hydroxamic derivatives.
Topics: Animals; Anti-Bacterial Agents; Hydrazines; Hydroxamic Acids; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Structure-Activity Relationship | 2022 |
In vitro and ex vivo activity of peptide deformylase inhibitors against Mycobacterium tuberculosis H37Rv.
Topics: Amidohydrolases; Animals; Antibiotics, Antitubercular; Dipeptides; Drug Synergism; Drug Therapy, Combination; Hydroxamic Acids; Hydroxylamine; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Phenanthrolines; Protease Inhibitors; Rifampin; Tuberculosis | 2009 |
Therapeutic potential of peptide deformylase inhibitors against experimental tuberculosis.
Topics: Amidohydrolases; Analysis of Variance; Animals; Antitubercular Agents; Colony Count, Microbial; Disease Models, Animal; Enzyme Inhibitors; Hydroxamic Acids; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Rifampin; Tuberculosis | 2010 |