Compounds > alpha-pyrrolidinopropiophenone
Page last updated: 2024-12-08

alpha-pyrrolidinopropiophenone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

alpha-pyrrolidinopropiophenone: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID209045
CHEBI ID180548
SCHEMBL ID11037118
MeSH IDM0469625

Synonyms (23)

Synonym
1-phenyl-2-pyrrolidin-1-ylpropan-1-one
CHEBI:180548
alpha-pyrrolidinopropiophenone
1-phenyl-2-(1-pyrrolidinyl)-1-propanone
1-propanone, 1-phenyl-2-(1-pyrrolidinyl)-
unii-01dp8ch58h
propiophenone, 2-(1-pyrrolidinyl)-
01dp8ch58h ,
19134-50-0
alpha-ppp
AKOS009049710
SCHEMBL11037118
a-pyrrolidinopropiophenone
KPUJAQRFIJAORQ-UHFFFAOYSA-N
J1.970.279K ,
.alpha.-pyrrolidino-propiophenone
.alpha.-pyrrolidinopropiophenone
.alpha.-ppp
1-phenyl-2-pyrrolidin-1-yl-propan-1-one
BCP07375
DTXSID50897462
Q4734920
PD048499

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
"Male, Swiss-Webster mice were exposed to α-PPP (80 mg/kg) using a binge-like dosing regimen (QID, q2h)."( Effects of the second-generation "bath salt" cathinone alpha-pyrrolidinopropiophenone (α-PPP) on behavior and monoamine neurochemistry in male mice.
Blough, BE; Canal, CE; Chitre, NM; Daphney, CM; Murnane, KS; Ray, A, 2019)		0.76
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
aromatic ketoneA ketone in which the carbonyl group is attached to an aromatic ring.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (12.50%)4.05%
Observational0 (0.00%)0.25%
Other7 (87.50%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
pyrroles
1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.		2.7830pyrrole;
secondary amine
thiophenes
Thiophenes: A monocyclic heteroarene furan in which the oxygen atom is replaced by a sulfur.. thiophenes : Compounds containing at least one thiophene ring.		2.1510mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound		non-polar solvent
methamphetamine
Methamphetamine: A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.. methamphetamine : A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.		2.5320amphetamines;
secondary amine		central nervous system stimulant;
environmental contaminant;
neurotoxin;
psychotropic drug;
xenobiotic
pyrovalerone
pyrovalerone: RN given refers to parent cpd; synonyms F 1983 & Centroton refer to HCl; structure		2.1710aromatic ketone
cathinone
cathinone: alkaloid from khat shrub, Catha edulis; RN given refers to parent cpd without isomeric designation. cathinone : The S stereoisomer of 2-aminopropiophenone.		7.86302-aminopropiophenone;
monoamine alkaloid		central nervous system stimulant;
psychotropic drug
4'-methyl-alpha-pyrrolidinopropiophenone
4'-methyl-alpha-pyrrolidinopropiophenone: structure in first source		7.4520aromatic ketone
1-phenyl-2-(1-pyrrolidinyl)-1-pentanone
alpha-pyrrolidinovalerophenone: a designer drug; structure in first source		2.6120
4-methylethcathinone
4-methylethcathinone: structure in first source		2.1110aromatic ketone
ConditionIndicatedRelationship StrengthStudiesTrials
Anterior Choroidal Artery Infarction
[description not available]		02.110
Acquired Encephalocele
[description not available]		02.110
Asystole
[description not available]		02.110
Cerebral Infarction
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).		02.110
Heart Arrest
Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.		02.110
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		02.1510