Page last updated: 2024-12-06

aconitic anhydride

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Description

Aconitic anhydride is a cyclic anhydride derived from aconitic acid. It is a white, crystalline solid with a melting point of 138–140 °C. Aconitic anhydride can be synthesized by the dehydration of aconitic acid. It is an important intermediate in the synthesis of various organic compounds, including polymers, pharmaceuticals, and agricultural chemicals. Aconitic anhydride is also used as a catalyst in some organic reactions. The biological activity of aconitic anhydride has been investigated, and it has been shown to inhibit the growth of certain bacteria and fungi. This compound is also of interest in the study of biological processes, as it is a close structural analog of citric acid, a key intermediate in the citric acid cycle.'

aconitic anhydride: RN refers to (cis)-isomer; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID65163
SCHEMBL ID225018
MeSH IDM0178577

Synonyms (47)

Synonym
(2,5-dioxo-2,5-dihydro-furan-3-yl)-acetic acid
cis-aconitic anhydride treated bsa
cis-aconitic anhydride treated casein
aconitic anhydride
6318-55-4
nsc31662
1-propene-1,3-tricarboxylic acid, cyclic 1,2-anhydride
cis-aconitic anhydride
cis-aconitic acid anhydride
nsc-31662
3-furanacetic acid,5-dihydro-2,5-dioxo-
2-(2,5-dioxo-3-furyl)acetic acid
3-furanacetic acid, 2,5-dihydro-2,5-dioxo-
cis-aconitic anhydride, 95%
A-2450
2-(2,5-dioxofuran-3-yl)acetic acid
1-propene-1,2,3-tricarboxylic acid, cyclic 1,2-anhydride
2,5-dihydro-2,5-dioxofuran-3-acetic acid
einecs 228-663-3
nsc 31662
6g00qn452a ,
unii-6g00qn452a
einecs 250-668-4
31511-11-2
(z)-prop-1-ene-1,2,3-tricarboxylic cyclic anhydride
FT-0623934
AKOS015893949
SCHEMBL225018
(2,5-dioxo-3-furyl)acetic acid
DTXSID8064228
(2,5-dioxo-2,5-dihydro-furan-3-yl)acetic acid
(2,5-dioxo-2,5-dihydro-3-furanyl)acetic acid
(z)-aconitic anhydride
(2,5-dioxo-2,5-dihydro-3-furanyl)acetic acid #
mfcd00005524
2-(2,5-dioxo-2,5-dihydrofuran-3-yl)acetic acid
BCP28868
(2,5-dihydro-2,5-dioxofur-3-yl)acetic acid
CS-0204449
(2,5-dioxo-2,5-dihydrofuran-3-yl)acetic acid
2,5-dihydro-2,5-dioxo-3-furanacetic acid
SB61008
SY027478
AS-0203
cis-propene-1,2,3-tricarboxylic anhydride
EN300-115946
trans-aconiticacidanhydride
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (14)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (14.29)18.7374
1990's2 (14.29)18.2507
2000's1 (7.14)29.6817
2010's9 (64.29)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 30.63

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index30.63 (24.57)
Research Supply Index2.83 (2.92)
Research Growth Index5.59 (4.65)
Search Engine Demand Index29.80 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (30.63)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other16 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]