| Assay ID | Title | Year | Journal | Article |
|---|
| AID642719 | Inhibition of human recombinant MAOA using kynuramine as substrate by fluorimetry | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3
| A scaffold hopping approach to identify novel monoamine oxidase B inhibitors. |
| AID452852 | Antioxidant activity assessed as hydroxyl radical scavenging activity at 100 uM | 2009 | Bioorganic & medicinal chemistry, Dec-01, Volume: 17, Issue:23
| Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity. |
| AID452848 | Antioxidant activity assessed as DPPH radical scavenging activity at 50 uM after 60 mins | 2009 | Bioorganic & medicinal chemistry, Dec-01, Volume: 17, Issue:23
| Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity. |
| AID452851 | Antioxidant activity assessed as superoxide anion radical scavenging activity at 10 uM | 2009 | Bioorganic & medicinal chemistry, Dec-01, Volume: 17, Issue:23
| Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity. |
| AID1656374 | Selectivity index, ratio of CC50 for dog MDCK cells to EC50 for Influenza A virus (H1N1) infected in dog MDCK cells | 2020 | Bioorganic & medicinal chemistry, 01-01, Volume: 28, Issue:1
| Design, synthesis and biological evaluation of substituted flavones and aurones as potential anti-influenza agents. |
| AID1173703 | Inhibition of HDAC in human HeLa cell extract at 100 uM after 15 mins by fluorescence assay | 2014 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
| Aurones as histone deacetylase inhibitors: identification of key features. |
| AID1499293 | Inhibition of TNF-alpha-induced adhesion of BCECF-labeled human U937 cells to human HT-29 cells at 10 uM preincubated for 1 hr followed by TNF-alpha challenge measured after 3 hrs by fluorescence microscopic method relative to control | 2017 | European journal of medicinal chemistry, Sep-08, Volume: 137 | Discovery and structure-activity relationship studies of 2-benzylidene-2,3-dihydro-1H-inden-1-one and benzofuran-3(2H)-one derivatives as a novel class of potential therapeutics for inflammatory bowel disease. |
| AID1656375 | Inhibition of Influenza A virus (H1N1) neuraminidase | 2020 | Bioorganic & medicinal chemistry, 01-01, Volume: 28, Issue:1
| Design, synthesis and biological evaluation of substituted flavones and aurones as potential anti-influenza agents. |
| AID1656372 | Cytotoxicity against dog MDCK cells assessed as reduction in cell viability by MTT assay | 2020 | Bioorganic & medicinal chemistry, 01-01, Volume: 28, Issue:1
| Design, synthesis and biological evaluation of substituted flavones and aurones as potential anti-influenza agents. |
| AID452853 | Antioxidant activity assessed as hydrogen peroxide scavenging activity by peroxyoxalate chemiluminescent method | 2009 | Bioorganic & medicinal chemistry, Dec-01, Volume: 17, Issue:23
| Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity. |
| AID452850 | Antioxidant activity assessed as DPPH radical scavenging activity at 100 uM after 60 mins | 2009 | Bioorganic & medicinal chemistry, Dec-01, Volume: 17, Issue:23
| Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity. |
| AID1173711 | Cytotoxicity against human HepG2 cells assessed as cell viability at 15 uM after 72 hrs by Celltitre-glo assay | 2014 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
| Aurones as histone deacetylase inhibitors: identification of key features. |
| AID1173713 | Inhibition of RAR-beta (unknown origin) assessed as change in DNA methylation | 2014 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
| Aurones as histone deacetylase inhibitors: identification of key features. |
| AID452847 | Antioxidant activity assessed as DPPH radical scavenging activity at 50 uM after 20 mins | 2009 | Bioorganic & medicinal chemistry, Dec-01, Volume: 17, Issue:23
| Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity. |
| AID1499297 | Potency index, ratio of test compound activity to 5-ASA activity for inhibition of TNF-alpha-induced adhesion of BCECF-labeled human U937 cells to human HT-29 cells at 10 uM | 2017 | European journal of medicinal chemistry, Sep-08, Volume: 137 | Discovery and structure-activity relationship studies of 2-benzylidene-2,3-dihydro-1H-inden-1-one and benzofuran-3(2H)-one derivatives as a novel class of potential therapeutics for inflammatory bowel disease. |
| AID642718 | Inhibition of human recombinant MAOB using kynuramine as substrate by fluorimetry | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3
| A scaffold hopping approach to identify novel monoamine oxidase B inhibitors. |
| AID1173712 | Modulation of sirtuin 2 (unknown origin) by thermal shift assay | 2014 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
| Aurones as histone deacetylase inhibitors: identification of key features. |
| AID1173710 | Cytotoxicity against human MCF7 cells assessed as cell viability at 15 uM after 72 hrs by Celltitre-glo assay | 2014 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23
| Aurones as histone deacetylase inhibitors: identification of key features. |
| AID452856 | Inhibition of soybean 5-lipoxygenase at 100 uM by UV-absorbance based enzyme assay | 2009 | Bioorganic & medicinal chemistry, Dec-01, Volume: 17, Issue:23
| Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity. |
| AID1656373 | Antiviral activity against Influenza A virus (H1N1) infected in dog MDCK cells assessed as reduction in log2HA titer incubated for 3 to 4 days by CPE assay | 2020 | Bioorganic & medicinal chemistry, 01-01, Volume: 28, Issue:1
| Design, synthesis and biological evaluation of substituted flavones and aurones as potential anti-influenza agents. |
| AID452849 | Antioxidant activity assessed as DPPH radical scavenging activity at 100 uM after 20 mins | 2009 | Bioorganic & medicinal chemistry, Dec-01, Volume: 17, Issue:23
| Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity. |
| AID452854 | Antioxidant activity assessed as inhibition of AAPH-induced lipid peroxidation at 10 uM by uV spectrophotometry | 2009 | Bioorganic & medicinal chemistry, Dec-01, Volume: 17, Issue:23
| Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity. |
| AID1653377 | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability | 2019 | European journal of medicinal chemistry, Mar-15, Volume: 166 | Aurone: A biologically attractive scaffold as anticancer agent. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |