Page last updated: 2024-12-05

pinane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Pinane is a bicyclic monoterpene hydrocarbon. It exists in two enantiomeric forms, (+)-pinane and (-)-pinane, which are found in various essential oils. Pinane is a key intermediate in the synthesis of other terpenes, such as pinene and camphor. It has been studied for its potential biological activities, including antimicrobial and anti-inflammatory effects. However, its specific effects and applications are not yet fully characterized. It is studied to understand its role in terpene biosynthesis and to explore its potential therapeutic applications.'

pinane: RN given refers to cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

pinane : A monoterpene that is bicyclo[3.1.1]heptane substituted by methyl groups at positions 2, 6 and 6. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID10129
CHEMBL ID1422299
CHEBI ID35710
MeSH IDM0095763

Synonyms (52)

Synonym
caswell no. 664
unii-996299pukb
996299pukb ,
epa pesticide chemical code 067001
bicyclo(3.1.1)heptane, 2,6,6-trimethyl-, didehydro deriv.
pinane, didehydro derivative
einecs 215-533-6
LS-13860
pinane, endo + exo
bicyclo[3.1.1]heptane, 2,6,6-trimethyl-, (1.alpha.,2.beta.,5.alpha.)-
2,6,6-trimethylbicyclo[3.1.1]heptane
bicyclo[3.1.1]heptane, 2,6,6-trimethyl-
NCIOPEN2_000688
CHEBI:35710 ,
nsc76674
bicyclo[3.1.1]heptane,6,6-trimethyl-
473-55-2
nsc-76674
2,6-trimethylbicyclo[3.1.1]heptane
dihydropinene
pinane
NCGC00090847-01
bicyclo(3.1.1)heptane, 2,6,6-trimethyl-
2,6,6-trimethylbicyclo(3.1.1)heptane
hsdb 5664
nsc 76674
einecs 207-467-1
1a,2b,5a-2,6,6-trimethylbicyclo(3.1.1)heptane
NCGC00090847-02
dtxcid705922
cas-473-55-2
tox21_303280
NCGC00257210-01
dtxsid7025922 ,
NCGC00259588-01
tox21_202039
AKOS015960556
unii-140v20yt81
140v20yt81 ,
(1s)-(-)-trans-pinane
FT-0623945
W-106074
CHEMBL1422299
bicyclo[3.1.1]heptane, 2,6,6-trimethyl-, [1r-(1.alpha.,2.beta.,5.alpha.)]-
2,6,6-trimethylbicyclo[3.1.1]heptane #
E75920
Q2095373
AS-14849
pinane (3-d1)
pinane (2-d1)
AKOS037643346
A872178
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
terpenoid fundamental parent
monoterpeneA C10 terpene.
carbobicyclic compoundA bicyclic compound in which all the ring atoms are carbon.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (3)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency23.39910.001022.650876.6163AID1224838
estrogen nuclear receptor alphaHomo sapiens (human)Potency26.15590.000229.305416,493.5996AID743069; AID743075; AID743077; AID743079; AID743080
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency5.23840.000323.4451159.6830AID743065
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (16)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (12.50)18.7374
1990's1 (6.25)18.2507
2000's6 (37.50)29.6817
2010's6 (37.50)24.3611
2020's1 (6.25)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 35.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index35.50 (24.57)
Research Supply Index2.89 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index43.69 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (35.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (11.76%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other15 (88.24%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]