Compounds > camphane
Page last updated: 2024-12-07

camphane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Camphane is a bicyclic monoterpene hydrocarbon with the molecular formula C10H18. It is a colorless, crystalline solid with a camphor-like odor. Camphane is found naturally in essential oils, particularly in the oil of rosemary. It is a relatively unreactive compound, but it can be synthesized from camphor by reduction with lithium aluminum hydride. Camphane is not known to have any significant biological effects, but it is a useful starting material for the synthesis of other camphor derivatives. Its importance lies in its structural similarity to camphor, making it a valuable model system for studying the reactivity and properties of camphor derivatives. The study of camphane contributes to our understanding of the structure, reactivity, and synthesis of terpene compounds, which are ubiquitous in nature and have a wide range of applications in various fields, including pharmaceuticals, fragrances, and food additives.'

camphane: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID92108
CHEBI ID35783
CHEBI ID41341
MeSH IDM0185717

Synonyms (28)

Synonym
CHEBI:35783
bornylane
nsc17531
bornane
1,7-trimethylbicyclo[2.2.1]heptane
nsc-17531
464-15-3
camphane
bicyclo[2.2.1]heptane,7,7-trimethyl-
inchi=1/c10h18/c1-9(2)8-4-6-10(9,3)7-5-8/h8h,4-7h2,1-3h
bicyclo[2.2.1]heptane, 1,7,7-trimethyl-
1,7,7-trimethylbicyclo[2.2.1]heptane
CAE ,
(1s,4s)-1,7,7-trimethylbicyclo[2.2.1]heptane
CHEBI:41341
1beta,4beta-bornane
DB04501
38451-93-3
AKOS006344945
bicyclo(2.2.1)heptane, 1,7,7-trimethyl-
1,7,7-trimethylbicyclo(2.2.1)heptane
nsc 17531
BEWYHVAWEKZDPP-UHFFFAOYSA-N
DTXSID60196832
bornane skeleton
1,7,7-trimethylbicyclo-[2.2.1]heptane
Q421333
Q27095272

Research Excerpts

Overview

Camphane (CAM) is a bulky fragment that disposes well on the wide gorge entrance.

ExcerptReferenceRelevance
"Camphane (CAM) is a bulky fragment that disposes well on the wide gorge entrance."( Docking-based design and synthesis of galantamine-camphane hybrids as inhibitors of acetylcholinesterase.
Doytchinova, I; Konstantinov, S; Philipova, I; Salamanova, E; Stavrakov, G; Valkova, I; Zheleva-Dimitrova, D, 2017)		1.43
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
terpenoid fundamental parent
monoterpeneA C10 terpene.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (18)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (33.33)18.7374
1990's3 (16.67)18.2507
2000's3 (16.67)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 34.05

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index34.05 (24.57)
Research Supply Index2.94 (2.92)
Research Growth Index4.58 (4.65)
Search Engine Demand Index44.85 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (34.05)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other18 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
carbon monoxide
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed). carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.		2.6930carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent
urea
pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.		6.9410isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2,2'-dipyridyl
2,2'-Dipyridyl: A reagent used for the determination of iron.. 2,2'-bipyridine : A bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'.		210bipyridinechelator;
ferroptosis inhibitor
camphor, (+-)-isomer
[no description available]		3.4580bornane monoterpenoid;
cyclic monoterpene ketone		plant metabolite
eucalyptol
[no description available]		2.0610
edetic acid
Edetic Acid: A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.		210ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
camphene
camphene : A monoterpene with a bicyclic skeleton that is bicyclo[2.2.1]heptane substituted by geminal methyl groups at position 2 and a methylidene group at position 3. It is a widespread natural product found in many essential oils.		210carbobicyclic compound;
monoterpene		fragrance;
plant metabolite
alpha-pinene
[no description available]		2.0510pineneplant metabolite
cyclohexanol
Cyclohexanols: Monohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers.. cyclohexanols : An alcohol in which one or more hydroxy groups are attached to a cyclohexane skeleton.		2.0610cyclohexanols;
secondary alcohol		solvent
adamantane
Adamantane: A tricyclo bridged hydrocarbon.		7.4120adamantanes;
polycyclic alkane
galantamine
Galantamine: A benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor that has been used to reverse the muscular effects of GALLAMINE TRIETHIODIDE and TUBOCURARINE and has been studied as a treatment for ALZHEIMER DISEASE and other central nervous system disorders.. galanthamine : A benzazepine alkaloid isolated from certain species of daffodils.		7.1510benzazepine alkaloid fundamental parent;
benzazepine alkaloid;
organic heterotetracyclic compound;
tertiary amino compound		antidote to curare poisoning;
cholinergic drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
plant metabolite
pinane
pinane: RN given refers to cpd without isomeric designation. pinane : A monoterpene that is bicyclo[3.1.1]heptane substituted by methyl groups at positions 2, 6 and 6.		2.0510carbobicyclic compound;
monoterpene;
terpenoid fundamental parent		plant metabolite
norcamphor
norcamphor: RN given refers to cpd without isomeric desination		2.4120
ruthenium
Ruthenium: A hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.		210iron group element atom;
platinum group metal atom
thiourea
Thiourea: A photographic fixative used also in the manufacture of resins. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance may reasonably be anticipated to be a carcinogen (Merck Index, 9th ed). Many of its derivatives are ANTITHYROID AGENTS and/or FREE RADICAL SCAVENGERS.. thiourea : The simplest member of the thiourea class, consisting of urea with the oxygen atom substituted by sulfur.		6.9410one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore
nadp
[no description available]		2.0610
ConditionIndicatedRelationship StrengthStudiesTrials