morpholinoanthracycline mx2 has been researched along with daunorubicin in 7 studies
| Studies (morpholinoanthracycline mx2) | Trials (morpholinoanthracycline mx2) | Recent Studies (post-2010) (morpholinoanthracycline mx2) | Studies (daunorubicin) | Trials (daunorubicin) | Recent Studies (post-2010) (daunorubicin) |
|---|---|---|---|---|---|
| 53 | 15 | 0 | 8,239 | 886 | 1,310 |
| Protein | Taxonomy | morpholinoanthracycline mx2 (IC50) | daunorubicin (IC50) |
|---|---|---|---|
| 72 kDa type IV collagenase | Homo sapiens (human) | 1.9 | |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | 8 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.047 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.22 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.02 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, O; Asanuma, F; Ishibiki, K; Josui, K; Kawamura, E; Koh, J; Kubota, T; Shiina, E; Suto, A; Yamada, Y | 1 |
| Bungo, M; Fourcade, A; Horichi, N; Kasahara, K; Lampidis, TJ; Nishiyama, M; Sasaki, Y; Sugimoto, Y; Takahashi, T; Tapiero, H | 1 |
| Majima, H | 1 |
| Bungo, M; Fujiwara, Y; Fukuda, M; Horichi, N; Minato, K; Nakagawa, K; Niimi, S; Ohe, Y; Saijo, N; Sasaki, Y | 1 |
| Kawai, H; Komeshima, N; Nakajima, S; Otake, N; Takeuchi, T; Tsuruo, T; Watanabe, M | 1 |
| Lampidis, TJ; Nguyen-Ba, G; Tapiero, H | 1 |
| Kuraishi, Y; Masaoka, T; Mizoguchi, H; Ogawa, M; Okabe, K; Saito, H; Sampi, K; Takemoto, Y; Tamura, K | 1 |
1 trial(s) available for morpholinoanthracycline mx2 and daunorubicin
| Article | Year |
|---|---|
A prospective randomized trial of KRN8602 and cytosine arabinoside vs. daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia. The KRN8602 Leukemia Study Group.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carubicin; Central Nervous System Diseases; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Treatment Outcome | 1999 |
6 other study(ies) available for morpholinoanthracycline mx2 and daunorubicin
| Article | Year |
|---|---|
Antitumor activity and pharmacokinetics of a morpholino-anthracycline derivative (KRN8602) against human breast carcinoma xenografts serially transplanted into nude mice.
Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Daunorubicin; Drug Administration Schedule; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Specific Pathogen-Free Organisms | 1990 |
3'-Deamino-3'-morpholino-13-deoxo-10-hydroxycarminomycin conquers multidrug resistance by rapid influx following higher frequency of formation of DNA single- and double-strand breaks.
Topics: Antibiotics, Antineoplastic; Biological Transport; Carubicin; Cell Line; Cell Nucleus; Cell Survival; Daunorubicin; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Single-Stranded; Doxorubicin; Drug Resistance; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Tumor Cells, Cultured | 1990 |
[Phase I clinical study of MX2 (KRN 8602)].
Topics: Adult; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Daunorubicin; Drug Evaluation; Female; Humans; Injections, Intravenous; Leukopenia; Male; Middle Aged; Nausea; Stomach Neoplasms; Vomiting | 1990 |
In vitro evaluation of the new anticancer agents KT6149, MX-2, SM5887, menogaril, and liblomycin using cisplatin- or adriamycin-resistant human cancer cell lines.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Carubicin; Cisplatin; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Menogaril; Mitomycins; Nogalamycin; Tumor Cells, Cultured | 1989 |
Role of DNA-binding in the cytotoxicity of an anthracycline, R20X2 and its morpholino analog, MX2.
Topics: Animals; Carubicin; Cells, Cultured; Daunorubicin; DNA, Neoplasm; Leukemia P388; Leukemia, Experimental; Rats; Structure-Activity Relationship | 1989 |
Cross resistance relevance of the chemical structure of different anthracyclines in multidrug resistant cells.
Topics: Aclarubicin; Animals; Carubicin; Cells, Cultured; Daunorubicin; DNA, Neoplasm; Doxorubicin; Drug Resistance; Humans; In Vitro Techniques; Mice; Tumor Cells, Cultured; Verapamil | 1994 |