Page last updated: 2024-08-05 11:44:09
tetracenes
Compounds containing a tetracene skeleton.
ChEBI ID: 51270
Members (4)
Member | Definition | Role |
---|---|---|
1-hydroxyaklavinone | (1R,2R,4S)-2-ethyl-2,4,5,7,10-pentahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylic acid methyl ester | |
amrubicin | A synthetic anthracycline antibiotic with molecular formula C25H25NO9. A specific inhibitor of topoisomerase II, it is used (particularly as the hydrochloride salt) in the treatment of cancer, especially lung cancer, where it is a prodrug for the active metabolite, ambrucinol. | amrubicin |
amrubicinol | A diastereoisomeric mixture resulting from the formal reduction of the acetyl group at position 9 of amrubicin to the corresponding 1-hydroxyethyl group. The active metabolite of amrubicin in lung cancer patients. | amrubicinol |
naphthacene | An acene that consists of four ortho-fused benzene rings in a rectilinear arrangement. | tetracene |
Research
Studies (266)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 13 (4.89) | 18.7374 |
1990's | 17 (6.39) | 18.2507 |
2000's | 80 (30.08) | 29.6817 |
2010's | 139 (52.26) | 24.3611 |
2020's | 17 (6.39) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 81 (27.00%) | 5.53% |
Reviews | 27 (9.00%) | 6.00% |
Case Studies | 30 (10.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 162 (54.00%) | 84.16% |