Page last updated: 2024-08-05 11:44:09

tetracenes

Compounds containing a tetracene skeleton.

ChEBI ID: 51270

Members (4)

MemberDefinitionRole
1-hydroxyaklavinone(1R,2R,4S)-2-ethyl-2,4,5,7,10-pentahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylic acid methyl ester
amrubicinA synthetic anthracycline antibiotic with molecular formula C25H25NO9. A specific inhibitor of topoisomerase II, it is used (particularly as the hydrochloride salt) in the treatment of cancer, especially lung cancer, where it is a prodrug for the active metabolite, ambrucinol.amrubicin
amrubicinolA diastereoisomeric mixture resulting from the formal reduction of the acetyl group at position 9 of amrubicin to the corresponding 1-hydroxyethyl group. The active metabolite of amrubicin in lung cancer patients.amrubicinol
naphthaceneAn acene that consists of four ortho-fused benzene rings in a rectilinear arrangement.tetracene

Research

Studies (266)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199013 (4.89)18.7374
1990's17 (6.39)18.2507
2000's80 (30.08)29.6817
2010's139 (52.26)24.3611
2020's17 (6.39)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials81 (27.00%)5.53%
Reviews27 (9.00%)6.00%
Case Studies30 (10.00%)4.05%
Observational0 (0.00%)0.25%
Other162 (54.00%)84.16%