Assay ID | Title | Year | Journal | Article |
AID743742 | Agonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by spectrofluorimetric analysis | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring. |
AID743632 | Inhibition of human recombinant MAGL-mediated 1,3-dihydroxypropan-1-yl 4-pyren-1-ylbutanoate conversion to 4-pyren-1-ylbutanoic acid preincubated for 15 mins measured after 45 mins by HPLC analysis | 2013 | European journal of medicinal chemistry, May, Volume: 63 | (4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). |
AID1734184 | Inhibition of MAGL (unknown origin) | 2016 | European journal of medicinal chemistry, Oct-04, Volume: 121 | Hit to lead optimization of a series of N-[4-(1,3-benzothiazol-2-yl)phenyl]acetamides as monoacylglycerol lipase inhibitors with potential anticancer activity. |
AID1363930 | Inhibition of FAAH in rat brain membranes | 2017 | Journal of medicinal chemistry, 01-12, Volume: 60, Issue:1
| Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors. |
AID743631 | Inhibition of FAAH in Sprague-Dawley rat brain microsomes assessed as N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide conversion to 4-pyren-1-ylbutanoic acid preincubated for 10 mins measured after 45 mins by HPLC analysis | 2013 | European journal of medicinal chemistry, May, Volume: 63 | (4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). |
AID382400 | Inhibition of MAGL mediated [14C]2-arachidonoyl glycerol hydrolysis in african green monkey COS cells | 2008 | European journal of medicinal chemistry, Jan, Volume: 43, Issue:1
| Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation. |
AID743741 | Antagonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ elevation incubated for 5 mins prior to capsaicin-stimulation by spectrofluorimetric analysis | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring. |
AID382401 | Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mins | 2008 | European journal of medicinal chemistry, Jan, Volume: 43, Issue:1
| Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation. |
AID743747 | Antagonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced intracellular Ca2+ elevation incubated for 5 mins prior to allyl isothiocyanate-stimulation by spectrofluorimetric analysis | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring. |
AID743740 | Agonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by spectrofluorimetric analysis relative to allyl isothiocyanate | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring. |
AID382405 | Inhibition of [14C]anandamide uptake in rat RBL-2H3 cells preincubated 10 mins before addition of [14C]anandamide | 2008 | European journal of medicinal chemistry, Jan, Volume: 43, Issue:1
| Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation. |
AID743743 | Agonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by spectrofluorimetric analysis relative to ionomycin | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring. |
AID382402 | Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 mins | 2008 | European journal of medicinal chemistry, Jan, Volume: 43, Issue:1
| Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation. |
AID743626 | Inhibition of cytosolic phospholipase A2alpha in porcine platelets assessed as 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine conversion to arachidonic acid at 10 uM by HPLC analysis | 2013 | European journal of medicinal chemistry, May, Volume: 63 | (4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). |
AID743739 | Agonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by spectrofluorimetric analysis | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |