Pathways > GPCR ligand binding
Page last updated: 2024-10-06

GPCR ligand binding

Proteins (192)

ProteinSynonymsTaxonomy
Glycoprotein hormones alpha chainAnterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; Homo sapiens (human)
Kininogen-1 Alpha-2-thiol proteinase inhibitor; Fitzgerald factor; High molecular weight kininogen; HMWK; Williams-Fitzgerald-Flaujeac factorHomo sapiens (human)
Oxytocin-neurophysin 1OT-NPIHomo sapiens (human)
PromotilinHomo sapiens (human)
PrepronociceptinHomo sapiens (human)
Taste receptor type 1 member 1G-protein coupled receptor 70Homo sapiens (human)
Receptor activity-modifying protein 3Calcitonin-receptor-like receptor activity-modifying protein 3; CRLR activity-modifying protein 3Homo sapiens (human)
Beta-2 adrenergic receptorBeta-2 adrenoreceptor; Beta-2 adrenoceptorHomo sapiens (human)
Muscarinic acetylcholine receptor M2Homo sapiens (human)
5-hydroxytryptamine receptor 1A5-HT-1A; 5-HT1A; G-21; Serotonin receptor 1AHomo sapiens (human)
D(2) dopamine receptorDopamine D2 receptorHomo sapiens (human)
Sphingosine 1-phosphate receptor 1S1P receptor 1; S1P1; Endothelial differentiation G-protein coupled receptor 1; Sphingosine 1-phosphate receptor Edg-1; S1P receptor Edg-1Homo sapiens (human)
fMet-Leu-Phe receptorfMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptorHomo sapiens (human)
Thromboxane A2 receptor TXA2-R; Prostanoid TP receptorHomo sapiens (human)
Histamine H2 receptorH2R; HH2R; Gastric receptor IHomo sapiens (human)
Substance-P receptorSPR; NK-1 receptor; NK-1R; Tachykinin receptor 1Homo sapiens (human)
Type-1 angiotensin II receptorAT1AR; AT1BR; Angiotensin II type-1 receptor; AT1Homo sapiens (human)
Gonadotropin-releasing hormone receptorGnRH receptor; GnRH-RHomo sapiens (human)
C-C chemokine receptor type 7C-C CKR-7; CC-CKR-7; CCR-7; BLR2; CDw197; Epstein-Barr virus-induced G-protein coupled receptor 1; EBI1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptorHomo sapiens (human)
C-X-C chemokine receptor type 5CXC-R5; CXCR-5; Burkitt lymphoma receptor 1; Monocyte-derived receptor 15; MDR-15Homo sapiens (human)
Histamine H1 receptorH1R; HH1RHomo sapiens (human)
C-C chemokine receptor type 6C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptorHomo sapiens (human)
Histamine H4 receptorH4R; HH4R; AXOR35; G-protein coupled receptor 105; GPRv53; Pfi-013; SP9144Homo sapiens (human)
G-protein coupled receptor 35Kynurenic acid receptor; KYNA receptorHomo sapiens (human)
Cysteinyl leukotriene receptor 2CysLTR2; G-protein coupled receptor GPCR21; hGPCR21; G-protein coupled receptor HG57; HPN321Homo sapiens (human)
Relaxin-3 receptor 1RLN3 receptor 1; G protein-coupled receptor SALPR; G-protein coupled receptor GPCR135; Relaxin family peptide receptor 3; Somatostatin- and angiotensin-like peptide receptorHomo sapiens (human)
Gamma-aminobutyric acid type B receptor subunit 1GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; Gb1Homo sapiens (human)
Histamine H3 receptorH3R; HH3R; G-protein coupled receptor 97Homo sapiens (human)
Complement decay-accelerating factorHomo sapiens (human)
Adhesion G protein-coupled receptor E5Leukocyte antigen CD97Homo sapiens (human)
G-protein coupled receptor 143Ocular albinism type 1 proteinHomo sapiens (human)
Prosaposin receptor GPR37Endothelin B receptor-like protein 1; ETBR-LP-1; G-protein coupled receptor 37; Parkin-associated endothelin receptor-like receptor; PAELRHomo sapiens (human)
Endothelin-1Preproendothelin-1; PPET1Homo sapiens (human)
G-protein coupled receptor family C group 6 member AhGPRC6A; G-protein coupled receptor GPCR33; hGPCR33Homo sapiens (human)
Corticotropin-releasing factor-binding proteinCRF-BP; CRF-binding protein; Corticotropin-releasing hormone-binding protein; CRH-BPHomo sapiens (human)
Taste receptor type 1 member 3Sweet taste receptor T1R3Homo sapiens (human)
Free fatty acid receptor 1G-protein coupled receptor 40Homo sapiens (human)
Free fatty acid receptor 3G-protein coupled receptor 41Homo sapiens (human)
ProthrombinEC 3.4.21.5; Coagulation factor IIHomo sapiens (human)
Muscarinic acetylcholine receptor M4Homo sapiens (human)
Beta-1 adrenergic receptorBeta-1 adrenoreceptor; Beta-1 adrenoceptorHomo sapiens (human)
Beta-3 adrenergic receptorBeta-3 adrenoreceptor; Beta-3 adrenoceptorHomo sapiens (human)
Substance-K receptorSKR; NK-2 receptor; NK-2R; Neurokinin A receptor; Tachykinin receptor 2Homo sapiens (human)
Lutropin-choriogonadotropic hormone receptorLH/CG-R; Luteinizing hormone receptor; LHR; LSH-RHomo sapiens (human)
C-X-C chemokine receptor type 1CXC-R1; CXCR-1; CDw128a; High affinity interleukin-8 receptor A; IL-8R A; IL-8 receptor type 1Homo sapiens (human)
C-X-C chemokine receptor type 2CXC-R2; CXCR-2; CDw128b; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; IL-8 receptor type 2Homo sapiens (human)
Endothelin-1 receptorEndothelin receptor type A; ET-A; ETA-R; hET-ARHomo sapiens (human)
Neuromedin-K receptorNKR; NK-3 receptor; NK-3R; Neurokinin B receptor; Tachykinin receptor 3Homo sapiens (human)
Vasopressin V2 receptorV2R; AVPR V2; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptorHomo sapiens (human)
Oxytocin receptorOT-RHomo sapiens (human)
Prostaglandin E2 receptor EP1 subtypePGE receptor EP1 subtype; PGE2 receptor EP1 subtype; Prostanoid EP1 receptorHomo sapiens (human)
Nociceptin receptorKappa-type 3 opioid receptor; KOR-3; Orphanin FQ receptorHomo sapiens (human)
Extracellular calcium-sensing receptorCaR; CaSR; hCasR; Parathyroid cell calcium-sensing receptor 1; PCaR1Homo sapiens (human)
P2Y purinoceptor 2P2Y2; ATP receptor; P2U purinoceptor 1; P2U1; P2U receptor 1; Purinergic receptorHomo sapiens (human)
Prostaglandin F2-alpha receptorPGF receptor; PGF2-alpha receptor; Prostanoid FP receptorHomo sapiens (human)
Prostaglandin E2 receptor EP3 subtypePGE receptor EP3 subtype; PGE2 receptor EP3 subtype; PGE2-R; Prostanoid EP3 receptorHomo sapiens (human)
Prostacyclin receptorProstaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptorHomo sapiens (human)
Glucagon receptorGL-RHomo sapiens (human)
Secretin receptorSCT-RHomo sapiens (human)
P2Y purinoceptor 1P2Y1; ADP receptor; Purinergic receptorHomo sapiens (human)
Hydroxycarboxylic acid receptor 3G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; Niacin receptor 2; Nicotinic acid receptor 2Homo sapiens (human)
C-X-C chemokine receptor type 3CXC-R3; CXCR-3; CKR-L2; G protein-coupled receptor 9; Interferon-inducible protein 10 receptor; IP-10 receptorHomo sapiens (human)
Type-2 angiotensin II receptorAngiotensin II type-2 receptor; AT2Homo sapiens (human)
C-C chemokine receptor type 8C-C CKR-8; CC-CKR-8; CCR-8; CC chemokine receptor CHEMR1; CMKBRL2; Chemokine receptor-like 1; CKR-L1; GPR-CY6; GPRCY6; TER1Homo sapiens (human)
Hydroxycarboxylic acid receptor 2G-protein coupled receptor 109A; G-protein coupled receptor HM74A; Niacin receptor 1; Nicotinic acid receptorHomo sapiens (human)
G-protein coupled bile acid receptor 1G-protein coupled receptor GPCR19; hGPCR19; Membrane-type receptor for bile acids; M-BAR; hBG37; BG37Homo sapiens (human)
Growth hormone secretagogue receptor type 1GHS-R; GH-releasing peptide receptor; GHRP; Ghrelin receptorHomo sapiens (human)
KiSS-1 receptorKiSS-1R; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; hOT7T175; Hypogonadotropin-1; Kisspeptins receptor; Metastin receptorHomo sapiens (human)
P2Y purinoceptor 12P2Y12; ADP-glucose receptor; ADPG-R; P2T(AC); P2Y(AC); P2Y(cyc); P2Y12 platelet ADP receptor; P2Y(ADP); SP1999Homo sapiens (human)
Prostaglandin D2 receptor 2Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44Homo sapiens (human)
Putative P2Y purinoceptor 10P2Y10; P2Y-like receptorHomo sapiens (human)
Atypical chemokine receptor 2C-C chemokine receptor D6; Chemokine receptor CCR-10; Chemokine receptor CCR-9; Chemokine-binding protein 2; Chemokine-binding protein D6Homo sapiens (human)
Relaxin receptor 2G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2Homo sapiens (human)
AngiotensinogenSerpin A8Homo sapiens (human)
12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor12-(S)-HETE receptor; 12-HETER; G-protein coupled receptor 31; GPR31/12-HETERHomo sapiens (human)
Tachykinin-3ZNEUROK1Homo sapiens (human)
Gamma-aminobutyric acid type B receptor subunit 2GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2; G-protein coupled receptor 51; HG20Homo sapiens (human)
CholecystokininCCKHomo sapiens (human)
Endothelin-converting enzyme 2ECE-2; EC 3.4.24.71Homo sapiens (human)
Interleukin-8IL-8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating proteHomo sapiens (human)
C-C motif chemokine 5EoCP; Eosinophil chemotactic cytokine; SIS-delta; Small-inducible cytokine A5; T cell-specific protein P228; TCP228; T-cell-specific protein RANTESHomo sapiens (human)
Follicle-stimulating hormone receptorFSH-R; Follitropin receptorHomo sapiens (human)
Pituitary adenylate cyclase-activating polypeptide type I receptorPACAP type I receptor; PACAP-R-1; PACAP-R1Homo sapiens (human)
Endothelin-converting enzyme 1ECE-1; EC 3.4.24.71Homo sapiens (human)
P2Y purinoceptor 4P2Y4; P2P; Uridine nucleotide receptor; UNRHomo sapiens (human)
P2Y purinoceptor 14P2Y14; G-protein coupled receptor 105; UDP-glucose receptorHomo sapiens (human)
Taste receptor type 1 member 2G-protein coupled receptor 71; Sweet taste receptor T1R2Homo sapiens (human)
P2Y purinoceptor 13P2Y13; G-protein coupled receptor 86; G-protein coupled receptor 94Homo sapiens (human)
Neurolysin, mitochondrialEC 3.4.24.16; Angiotensin-binding protein; Microsomal endopeptidase; MEP; Mitochondrial oligopeptidase M; Neurotensin endopeptidaseHomo sapiens (human)
C-C chemokine receptor-like 2Chemokine receptor CCR11; Chemokine receptor X; Putative MCP-1 chemokine receptorHomo sapiens (human)
Lysophosphatidic acid receptor 6LPA receptor 6; LPA-6; Oleoyl-L-alpha-lysophosphatidic acid receptor; P2Y purinoceptor 5; P2Y5; Purinergic receptor 5; RB intron encoded G-protein coupled receptorHomo sapiens (human)
2-oxoglutarate receptor 1Alpha-ketoglutarate receptor 1; G-protein coupled receptor 80; G-protein coupled receptor 99; P2Y purinoceptor 15; P2Y15; P2Y-like GPCR; P2Y-like nucleotide receptorHomo sapiens (human)
Succinate receptor 1G-protein coupled receptor 91; P2Y purinoceptor 1-likeHomo sapiens (human)
Relaxin receptor 1Leucine-rich repeat-containing G-protein coupled receptor 7; Relaxin family peptide receptor 1Homo sapiens (human)
Chemokine-like receptor 1G-protein coupled receptor ChemR23; G-protein coupled receptor DEZHomo sapiens (human)
Complement C5C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4Homo sapiens (human)
C5a anaphylatoxin chemotactic receptor 2Complement component 5a receptor 2; G-protein coupled receptor 77Homo sapiens (human)
C-X-C chemokine receptor type 6CXC-R6; CXCR-6; CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzoHomo sapiens (human)
Free fatty acid receptor 2G-protein coupled receptor 43Homo sapiens (human)
Motilin receptorG-protein coupled receptor 38Homo sapiens (human)
Orexin receptor type 1Ox-1-R; Ox1-R; Ox1R; Hypocretin receptor type 1Homo sapiens (human)
Orexin receptor type 2Ox-2-R; Ox2-R; Ox2R; Hypocretin receptor type 2Homo sapiens (human)
Receptor activity-modifying protein 1Calcitonin-receptor-like receptor activity-modifying protein 1; CRLR activity-modifying protein 1Homo sapiens (human)
Receptor activity-modifying protein 2Calcitonin-receptor-like receptor activity-modifying protein 2; CRLR activity-modifying protein 2Homo sapiens (human)
Glucagon-like peptide 2 receptorGLP-2 receptor; GLP-2-R; GLP-2RHomo sapiens (human)
Islet amyloid polypeptideAmylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptideHomo sapiens (human)
C5a anaphylatoxin chemotactic receptor 1C5a anaphylatoxin chemotactic receptor; C5a-R; C5aRHomo sapiens (human)
N-formyl peptide receptor 2FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFPHomo sapiens (human)
Platelet-activating factor receptorPAF-R; PAFrHomo sapiens (human)
Calcitonin receptorCT-RHomo sapiens (human)
Thyrotropin-releasing hormone receptorTRH-R; Thyroliberin receptorHomo sapiens (human)
Glucagon-like peptide 1 receptorGLP-1 receptor; GLP-1-R; GLP-1RHomo sapiens (human)
C-C chemokine receptor type 10C-C CKR-10; CC-CKR-10; CCR-10; G-protein coupled receptor 2Homo sapiens (human)
Gastric inhibitory polypeptide receptorGIP-R; Glucose-dependent insulinotropic polypeptide receptorHomo sapiens (human)
CX3C chemokine receptor 1C-X3-C CKR-1; CX3CR1; Beta chemokine receptor-like 1; CMK-BRL-1; CMK-BRL1; Fractalkine receptor; G-protein coupled receptor 13; V28Homo sapiens (human)
C-C chemokine receptor type 9C-C CKR-9; CC-CKR-9; CCR-9; G-protein coupled receptor 28; GPR-9-6Homo sapiens (human)
Prostaglandin D2 receptorPGD receptor; PGD2 receptor; Prostanoid DP receptorHomo sapiens (human)
N-arachidonyl glycine receptorNAGly receptor; G-protein coupled receptor 18Homo sapiens (human)
P2Y purinoceptor 6P2Y6Homo sapiens (human)
Atypical chemokine receptor 1Duffy antigen/chemokine receptor; Fy glycoprotein; GpFy; Glycoprotein D; Plasmodium vivax receptorHomo sapiens (human)
C3a anaphylatoxin chemotactic receptorC3AR; C3a-RHomo sapiens (human)
Calcitonin gene-related peptide type 1 receptorCGRP type 1 receptor; Calcitonin receptor-like receptorHomo sapiens (human)
Free fatty acid receptor 4G-protein coupled receptor 120; G-protein coupled receptor 129; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; Omega-3 fatty acid receptor 1Homo sapiens (human)
Neuropeptide S receptorG-protein coupled receptor 154; G-protein coupled receptor PGR14; G-protein coupled receptor for asthma susceptibilityHomo sapiens (human)
Oxoeicosanoid receptor 15-oxo-ETE G-protein coupled receptor; G-protein coupled receptor 170; G-protein coupled receptor R527; G-protein coupled receptor TG1019Homo sapiens (human)
P2Y purinoceptor 11P2Y11Homo sapiens (human)
Pyroglutamylated RF-amide peptide receptorAQ27; G-protein coupled receptor 103; Orexigenic neuropeptide QRFP receptor; SP9155Homo sapiens (human)
G-protein coupled estrogen receptor 1Chemoattractant receptor-like 2; Flow-induced endothelial G-protein coupled receptor 1; FEG-1; G protein-coupled estrogen receptor 1; G-protein coupled receptor 30; GPCR-Br; IL8-related receptor DRY12; Lymphocyte-derived G-protein coupled receptor; LYGPR;Homo sapiens (human)
Lysophosphatidic acid receptor 4LPA receptor 4; LPA-4; G-protein coupled receptor 23; P2Y purinoceptor 9; P2Y9; P2Y5-like receptor; Purinergic receptor 9Homo sapiens (human)
Smoothened homologSMO; Protein GxHomo sapiens (human)
Hydroxycarboxylic acid receptor 1G-protein coupled receptor 104; G-protein coupled receptor 81Homo sapiens (human)
Urotensin-2 receptorUR-2-R; G-protein coupled receptor 14; Urotensin II receptor; UR-II-RHomo sapiens (human)
Cysteinyl leukotriene receptor 1CysLTR1; Cysteinyl leukotriene D4 receptor; LTD4 receptor; G-protein coupled receptor HG55; HMTMF81Homo sapiens (human)
Complement C3C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1Homo sapiens (human)
Stromal cell-derived factor 1SDF-1; hSDF-1; C-X-C motif chemokine 12; Intercrine reduced in hepatomas; IRH; hIRH; Pre-B cell growth-stimulating factor; PBSFHomo sapiens (human)
Prolactin-releasing peptide receptorPrRP receptor; PrRPR; G-protein coupled receptor 10; hGR3Homo sapiens (human)
Adrenocorticotropic hormone receptorACTH receptor; ACTH-R; Adrenocorticotropin receptor; Melanocortin receptor 2; MC2-RHomo sapiens (human)
OrexinHypocretin; HcrtHomo sapiens (human)
Endothelin-3ET-3; Preproendothelin-3; PPET3Homo sapiens (human)
Kell blood group glycoproteinEC 3.4.24.-Homo sapiens (human)
Insulin-like 3Leydig insulin-like peptide; Ley-I-L; Relaxin-like factorHomo sapiens (human)
G-protein coupled receptor 39Homo sapiens (human)
Thyrotropin receptorThyroid-stimulating hormone receptor; TSH-RHomo sapiens (human)
G-protein coupled receptor 183Epstein-Barr virus-induced G-protein coupled receptor 2; EBI2; EBV-induced G-protein coupled receptor 2; hEBI2Homo sapiens (human)
Apelin receptorAngiotensin receptor-like 1; G-protein coupled receptor APJ; G-protein coupled receptor HG11Homo sapiens (human)
Uracil nucleotide/cysteinyl leukotriene receptorUDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12Homo sapiens (human)
Relaxin-3 receptor 2RLN3 receptor 2; G-protein coupled receptor 100; G-protein coupled receptor GPCR142; Insulin-like peptide INSL5 receptor; Relaxin family peptide receptor 4Homo sapiens (human)
Neuropeptide SHomo sapiens (human)
C-C motif chemokine 25Chemokine TECK; Small-inducible cytokine A25; Thymus-expressed chemokineHomo sapiens (human)
G-protein coupled receptor 37-like 1Endothelin B receptor-like protein 2; ETBR-LP-2Homo sapiens (human)
Pro-glucagonHomo sapiens (human)
VIP peptidesHomo sapiens (human)
Growth hormone-releasing hormone receptorGHRH receptor; Growth hormone-releasing factor receptor; GRF receptor; GRFRHomo sapiens (human)
Neuromedin-U receptor 2NMU-R2; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1Homo sapiens (human)
Chemokine XC receptor 1G-protein coupled receptor 5; Lymphotactin receptor; XC chemokine receptor 1Homo sapiens (human)
C-X-C motif chemokine 13Angie; B cell-attracting chemokine 1; BCA-1; B lymphocyte chemoattractant; CXC chemokine BLC; Small-inducible cytokine B13Homo sapiens (human)
Pro-opiomelanocortinPOMC; Corticotropin-lipotropinHomo sapiens (human)
CalcitoninHomo sapiens (human)
SomatoliberinGrowth hormone-releasing factor; GRF; Growth hormone-releasing hormone; GHRH; Somatocrinin; SomatorelinHomo sapiens (human)
CorticoliberinCorticotropin-releasing factor; CRF; Corticotropin-releasing hormoneHomo sapiens (human)
Gastric inhibitory polypeptideGIP; Glucose-dependent insulinotropic polypeptide; Incretin hormoneHomo sapiens (human)
SecretinHomo sapiens (human)
MelanopsinOpsin-4Homo sapiens (human)
Relaxin-3Insulin-like peptide INSL7; Insulin-like peptide 7; Prorelaxin H3Homo sapiens (human)
C-C motif chemokine 20Beta-chemokine exodus-1; CC chemokine LARC; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; MIP-3-alpha; Small-inducible cytokine A20Homo sapiens (human)
FractalkineC-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1Homo sapiens (human)
Metastasis-suppressor KiSS-1Kisspeptin-1Homo sapiens (human)
Galanin peptidesHomo sapiens (human)
C-C motif chemokine 19Beta-chemokine exodus-3; CK beta-11; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Macrophage inflammatory protein 3 beta; MIP-3-beta; Small-inducible cytokine A19Homo sapiens (human)
Pro-FMRFamide-related neuropeptide FFFMRFamide-related peptidesHomo sapiens (human)
C-C motif chemokine 16Chemokine CC-4; HCC-4; Chemokine LEC; IL-10-inducible chemokine; LCC-1; Liver-expressed chemokine; Lymphocyte and monocyte chemoattractant; LMC; Monotactin-1; MTN-1; NCC-4; Small-inducible cytokine A16Homo sapiens (human)
Vasopressin-neurophysin 2-copeptinAVP-NPIIHomo sapiens (human)
Thyrotropin subunit betaThyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chainHomo sapiens (human)
Follitropin subunit betaFollicle-stimulating hormone beta subunit; FSH-B; FSH-beta; Follitropin beta chainHomo sapiens (human)
Lutropin subunit betaLutropin beta chain; Luteinizing hormone subunit beta; LH-B; LSH-B; LSH-betaHomo sapiens (human)
Prorelaxin H2Homo sapiens (human)
Protachykinin-1PPTHomo sapiens (human)
Pro-MCHHomo sapiens (human)
C-C motif chemokine 1Small-inducible cytokine A1; T lymphocyte-secreted protein I-309Homo sapiens (human)
N-formyl peptide receptor 3FMLP-related receptor II; FMLP-R-II; Formyl peptide receptor-like 2Homo sapiens (human)
Neurotensin/neuromedin NHomo sapiens (human)
Neuromedin-UHomo sapiens (human)
Membrane transport protein XKKell complex 37 kDa component; Kx antigen; XK-related protein 1Homo sapiens (human)
Orexigenic neuropeptide QRFPP518Homo sapiens (human)
Neuromedin-SHomo sapiens (human)
Glycoprotein hormone beta-5Thyrostimulin subunit betaHomo sapiens (human)
Putative gonadotropin-releasing hormone II receptorGnRH II receptor; GnRH-II-R; Type II GnRH receptorHomo sapiens (human)
Glycoprotein hormone alpha-2Putative secreted protein Zsig51; Thyrostimulin subunit alphaHomo sapiens (human)
C-C motif chemokine 13CK-beta-10; Monocyte chemoattractant protein 4; Monocyte chemotactic protein 4; MCP-4; NCC-1; Small-inducible cytokine A13Homo sapiens (human)
C-X-C motif chemokine 16Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16; Transmembrane chemokine CXCL16Homo sapiens (human)
Atypical chemokine receptor 4C-C chemokine receptor type 11; C-C CKR-11; CC-CKR-11; CCR-11; CC chemokine receptor-like 1; CCRL1; CCX CKRHomo sapiens (human)
Insulin-like peptide INSL5Insulin-like peptide 5Homo sapiens (human)

Compounds (35)

CompoundDescription
hydronium ion
l-lactic acid
Succinate
AcetylcholineA neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
Dopamine Hydrochloride
dinoprostoneThe most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.
dinoprostA naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.
epoprostenolA prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
adenosineA nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Uridine TriphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
melatoninA biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
phenethylamineRN given refers to parent cpd; structure in Merck Index, 9th ed, #7016
7,25-dihydroxycholesterolhas various immunosupressive effects; RN given refers to (3beta)-isomer; RN for cpd without isomeric designation not available 12/88
alpha-Ketoglutarate
kynurenic acidA broad-spectrum excitatory amino acid antagonist used as a research tool.
SerotoninA biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
leukotriene b4The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
thromboxane a2An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).
12-hydroxy-5,8,10,14-eicosatetraenoic acidA lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)
5-oxo-6,8,11,14-eicosatetraenoic acidRN given is for cpd without isomeric designation; an arachidonate metabolite which stimulates neutrophils to mobilize Ca and promotes PMN degranulation responses
n-arachidonylglycinestructure in first source
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Peremin
1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholinereported to have same biological activity as natural PAF-acether; RN given refers to parent cpd without isomeric designation
n-formylmethionine leucyl-phenylalanineA formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them to release lysosomal enzymes and become metabolically activated.
prostaglandin d2The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
sphingosine 1-phosphateRN given refers to (R-(R*,S*-(E)))-isomer; RN for cpd without isomeric designation not available 8/89
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