6-aminonicotinic acid

Description

6-Aminonicotinic acid is a pyridine derivative that has shown potential as a building block for various pharmaceutical compounds. It is synthesized through a multi-step process, often starting from nicotinic acid (niacin) and involves reactions like nitration, reduction, and hydrolysis. Research into 6-aminonicotinic acid is driven by its potential as a precursor for drugs targeting different biological pathways, including those involved in neurotransmission, inflammation, and cancer. This compound has demonstrated promising anti-inflammatory and analgesic properties in preliminary studies, suggesting its potential for treating chronic pain and inflammatory diseases. Its ability to act as a substrate for enzymes involved in neurotransmitter synthesis, such as nicotinamide adenine dinucleotide (NAD) biosynthesis, makes it an interesting target for studying the regulation of neuronal function and development.'

6-aminonicotinic acid: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

6-aminonicotinic acid : An aminonicotinic acid in which the amino group is situated at position 6 of the pyridine ring. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]