irganox 1076

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID Source	ID
PubMed CID	16386
SCHEMBL ID	18856
MeSH ID	M0082873

Synonyms (106)

Synonym
AC-15275
BIDD:ER0412
2082-79-3
octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate
benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, octadecyl ester
octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate, 99%
irganox 1976
stearyl 3-(4-hydroxy-3,5-di-tert-butyl-4-hydroxyphenyl)propionate
einecs 218-216-0
octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
irganox i 1076
ir 1076
mark ao 50
octadecyl 3-(3',5'-di-tert-butyl-4'-hydroxyphenyl)propionate
hydrocinnamic acid, 3,5-di-tert-butyl-4-hydroxy-, octadecyl ester
stearyl 3,5-di-tert-butyl-4-hydroxyhydrocinnamate
3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoic acid octadecyl ester
stearyl beta-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
tominokusu ss
ultranox 276
c35h62o3
u 276
ralox 530
e 376
irganox l 107
hsdb 5865
sumilizer bp 76
adk stab ao 50
anox pp 18
irganox 1076
stearyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
irganox 1906
naugard 76
i 1076
hydrocinnamic acid, 3,5-di-t-butyl-4-hydroxy-, octadecyl ester
octadecyl 3,5-di-tert-butyl-4-hydroxyhydrocinnamate
antioxidant 1076 ,
octadecyl 3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoate
dibutylhydroxyphenylpropionic acid stearyl ester
FT-0655079
inchi=1/c35h62o3/c1-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-26-38-32(36)25-24-29-27-30(34(2,3)4)33(37)31(28-29)35(5,6)7/h27-28,37h,8-26h2,1-7h3
ssdscdgvmjfteq-uhfffaoysa-
D1644
3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid stearyl ester
octadecyl-3-(3,5-di-tert.butyl-4-hydroxyphenyl)-propionate
octadecyl 3,5-bis(tert-butyl)-4-hydroxyhydrocinnamate
unii-v88j661g2p
ec 218-216-0
v88j661g2p ,
A814953
AKOS015890027
irganox-1076
stearyl 3,5-di-tert-butyl-4-hydroxhydrocinnamate
tinogard ts
3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid octadecyl ester
songnox 1076
3-(3,5-di-tert-butyl-4-hydroxyphenol)propionic acid octadecyl ester
plastic additive 4
2,6-di-tert-butyl-4-(octadecanoxycarbonylethyl)phenol
octadecyl di-t-butyl-4-hydroxyhydrocinnamate [inci]
plastic additive 4 [usp-rs]
3,5-di-tert-butyl-4-hydroxyphenylpropionic acid octadecyl ester
stearyl 3-(4-hydroxy-3,5-di-tert-butyl-4- hydroxyphenyl)propionate
octadecyl-3-(3',5'-di-tert-butyl-4'-hydroxyphenyl)propionate
octadecyl .beta.-(4-hydroxy-3,5-di-tert-butylphenyl)propionate
octadecyl 3-(3,5-bis(1,1-dimethylethyl)-4-hydroxybenzene)propionate
n-octadecyl-3-(3',5'-di-tert-butyl-4'-hydroxyphenyl)propionate
hydrocinnamic acid, 3,5-di-t-butyl-4-hydroxy-, octadecyl ester [hsdb]
selosol f 773
octadecyl 3,5-di-tert-butyl-4-oxyphenylpropionate
octadecyl 3,5-di-t-butyl-4-hydroxy-hydrocinnamate
octadecyl di-tert-butyl-4-hydroxyhydrocinnamate
octadecyl .beta.-(4'-hydroxy-3',5'-di-tert-butylphenyl)propionate
octadecyl di-t-butyl-4-hydroxyhydrocinnamate
stearyl 3-(4-hydroxy-3,5-di-t-butylphenyl)propionate
n-octadecyl-3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
n-octadecyl 3,5-di-tert-butyl-4-hydroxyhydrocinnamate
beta-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid octadecyl ester
n-octadecyl beta-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
octadecyl 3,5-di-t-butyl-4-hydroxyhydrocinnamate
octadecyl 3-(3,5-di-t-butyl-4-hydroxyphenyl)propionate
octadecyl 3-(3,5-di-tertbutyl-4-hydroxyphenyl)-propionate
octadecyl-3,5-di-tert-butyl-4-hydroxy-hydrocinnamate
SCHEMBL18856
octadecyl-3,5-di-t-butyl-4-hydroxyhydrocinnamate
W-107592
octadecyl3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
octadecyl 3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoate #
stearyl .beta.-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
octadecyl-3,5-di-tert-butyl-4-hydroxyhydrocinnamate
2,6-di-tert-butyl-4-[(2-octadecyloxycarbonyl)ethyl]phenol
octadecyl-3(3',5'-di-t-butyl-4'-hydroxyphenyl)propionate
lowinox po35
octadecyl 3-(3,5-di-t-butyl-4-hydroxyphenyl) propionate
DTXSID8027456
mfcd00017498
3-(3',5'-di-tert-butyl-4'-hydroxyphenyl)propionic acid stearyl ester
plastic additive 4, united states pharmacopeia (usp) reference standard
irganox 1076, 98%
plastic additive 11, european pharmacopoeia (ep) reference standard
AS-12172
benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-,octadecyl ester
D70534
Q27291662
irganox 1076 100 microg/ml in acetonitrile
CS-0152197

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (19)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	3 (15.79)	18.7374
1990's	2 (10.53)	18.2507
2000's	5 (26.32)	29.6817
2010's	9 (47.37)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 49.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	49.50 (24.57)
Research Supply Index	3.00 (2.92)
Research Growth Index	4.82 (4.65)
Search Engine Demand Index	73.62 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (49.50)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (5.26%)	6.00%
Case Studies	1 (5.26%)	4.05%
Observational	0 (0.00%)	0.25%
Other	17 (89.47%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
benzene [no description available]	2.02	1	aromatic annulene; benzenes; volatile organic compound	carcinogenic agent; environmental contaminant; non-polar solvent
octane Octanes: Eight-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives.. octane : A straight chain alkane composed of 8 carbon atoms.	1.99	1	alkane	xenobiotic
phthalic acid phthalic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7178. phthalic acid : A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.	2.11	1	benzenedicarboxylic acid	human xenobiotic metabolite
1-anilino-8-naphthalenesulfonate 1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.	2.17	1	aminonaphthalene; naphthalenesulfonic acid	fluorescent probe
phenobarbital Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.. phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.	1.95	1	barbiturates	anticonvulsant; drug allergen; excitatory amino acid antagonist; sedative
chloroform Chloroform: A commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.. chloroform : A one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines.	2	1	chloromethanes; one-carbon compound	carcinogenic agent; central nervous system drug; inhalation anaesthetic; non-polar solvent; refrigerant
acetonitrile acetonitrile: RN given refers to unlabeled cpd. acetonitrile : A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a methyl group.	2	1	aliphatic nitrile; volatile organic compound	EC 3.5.1.4 (amidase) inhibitor; NMR chemical shift reference compound; polar aprotic solvent
benzotriazole benzotriazole: inhibitor of atmospheric metal corrosion; also component of motion picture film & Neva brake fluid. benzotriazole : The simplest member of the class of benzotriazoles that consists of a benzene nucleus fused to a 1H-1,2,3-triazole ring.	2.15	1	benzotriazoles	environmental contaminant; xenobiotic
terephthalic acid terephthalic acid: RN given refers to 1,4-benzenedicarboxylic acid. terephthalic acid : A benzenedicarboxylic acid carrying carboxy groups at positions 1 and 4. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and isophthalic acids.	2.11	1	benzenedicarboxylic acid
styrene Styrene: A colorless, toxic liquid with a strong aromatic odor. It is used to make rubbers, polymers and copolymers, and polystyrene plastics.. styrene : A vinylarene that is benzene carrying a vinyl group. It has been isolated from the benzoin resin produced by Styrax species.	2.02	1	styrenes; vinylarene; volatile organic compound	mouse metabolite; mutagen; plant metabolite
caprolactam Caprolactam: Cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. Can cause local irritation.. epsilon-caprolactam : A member of the class of caprolactams that is azepane substituted by an oxo group at position 2.	2.02	1	caprolactams	human blood serum metabolite
diethylhexyl phthalate Diethylhexyl Phthalate: An ester of phthalic acid. It appears as a light-colored, odorless liquid and is used as a plasticizer for many resins and elastomers.. bis(2-ethylhexyl) phthalate : A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.	2.02	1	diester; phthalate ester	androstane receptor agonist; apoptosis inhibitor; plasticiser
2,2,4-trimethylpentane 2,2,4-trimethylpentane: nephrotoxic. isooctane : An alkane that consists of pentane bearing two methyl substituents at position 2 and a single methyl substituent at position 4.	1.99	1	alkane; volatile organic compound	fuel additive; nephrotoxin; non-polar solvent
d-alpha tocopherol Vitamin E: A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.. tocopherol : A collective name for a group of closely related lipids that contain a chroman-6-ol nucleus substituted at position 2 by a methyl group and by a saturated hydrocarbon chain consisting of three isoprenoid units. They are designated as alpha-, beta-, gamma-, and delta-tocopherol depending on the number and position of additional methyl substituents on the aromatic ring. Tocopherols occur in vegetable oils and vegetable oil products, almost exclusively with R,R,R configuration. Tocotrienols differ from tocopherols only in having three double bonds in the hydrocarbon chain.. vitamin E : Any member of a group of fat-soluble chromanols that exhibit biological activity against vitamin E deficiency. The vitamers in this class consists of a chroman-6-ol core which is substituted at position 2 by a methyl group and (also at position 2) either a saturated or a triply-unsaturated hydrocarbon chain consisting of three isoprenoid units. The major function of vitamin E is to act as a natural antioxidant by scavenging free radicals and molecular oxygen.. (R,R,R)-alpha-tocopherol : An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.	1.96	1	alpha-tocopherol	algal metabolite; antiatherogenic agent; anticoagulant; antioxidant; antiviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunomodulator; micronutrient; nutraceutical; plant metabolite
(2-hydroxy-4-(octyloxy)phenyl)phenylmethanone 2-hydroxy-4-octyloxybenzophenone: exhibits pseudo-positive initiation activity in carcinogenesis; structure in first source	2.02	1	benzophenones
dioctyl adipate [no description available]	1.99	1	carboxylic ester
butyl stearate butyl octadecanoate : A fatty acid ester that is the butyl ester of stearic acid.	1.96	1	fatty acid ester	algal metabolite
amcinonide [no description available]	2.11	1	diester; phthalate ester
irganox 1010 pentaerythritol tetrakis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate): has antioxidant activity	2.79	3
triazoles Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.	2.15	1	1,2,3-triazole
tris-(2,4-di-tert-butylphenyl) phosphite tris-(2,4-di-tert-butylphenyl) phosphite: structure given in first source	2.43	2	alkylbenzene
irganox 3114 Irganox 3114: structure in first source	2.11	1
2,2,5,7,8-pentamethyl-1-hydroxychroman 2,2,5,7,8-pentamethyl-1-hydroxychroman: a Vitamin E derivative. chromanol : Any member of the class of chromanes that is chromane substituted by one or more hydroxy groups.	1.96	1
phosphites Phosphites: Inorganic salts or organic esters of phosphorous acid that contain the (3-)PO3 radical. (From Grant & Hackh's Chemical Dictionary, 5th ed). phosphite(3-) : A trivalent inorganic anion obtained by removal of all three protons from phosphorous acid.	2.43	2	phosphite ion; trivalent inorganic anion
lignin Lignin: The most abundant natural aromatic organic polymer found in all vascular plants. Lignin together with cellulose and hemicellulose are the major cell wall components of the fibers of all wood and grass species. Lignin is composed of coniferyl, p-coumaryl, and sinapyl alcohols in varying ratios in different plant species. (From Merck Index, 11th ed). lignin : A polyphenylpropanoid derived from three monolignol monomers: trans-p-coumaryl alcohol, coniferol and trans-sinapyl alcohol. There is extensive cross-linking and no defined primary structure.	2.17	1
ferulic acid ferulate : A monocarboxylic acid anion obtained by the deprotonation of the carboxy group of ferulic acid.	2.17	1	ferulic acids	anti-inflammatory agent; antioxidant; apoptosis inhibitor; cardioprotective agent; MALDI matrix material; plant metabolite
1,4-diphenylbutadiene [no description available]	2.02	1	styrenes
methyl linoleate [no description available]	1.96	1	fatty acid methyl ester	plant metabolite
phosphatidylcholines Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.	1.96	1	1,2-diacyl-sn-glycero-3-phosphocholine
stearates Stearates: Salts and esters of the 18-carbon saturated, monocarboxylic acid--stearic acid.	1.96	1

Condition	Relationship Strength	Studies
Allergic Contact Dermatitis [description not available]	7.17	1
Dermatitis, Allergic Contact A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.	2.17	1
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	1.95	1

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