Page last updated: 2024-12-08
basic red 51
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
Basic Red 51: a semi-permanent hair dye, cytotoxic to human skin cells; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 166491 |
| SCHEMBL ID | 334242 |
| SCHEMBL ID | 334243 |
| MeSH ID | M000595155 |
Synonyms (40)
| Synonym |
|---|
| 77061-58-6 |
| 12270-25-6 |
| 2-((4-(dimethylamino)phenyl)azo)-1,3-dimethyl-1h-imidazolium chloride |
| basic red 51 |
| 1h-imidazolium, 2-(2-(4-(dimethylamino)phenyl)diazenyl)-1,3-dimethyl-, chloride (1:1) |
| einecs 278-601-4 |
| 1h-imidazolium, 2-((4-(dimethylamino)phenyl)azo)-1,3-dimethyl-, chloride |
| unii-a7a946jj6i |
| a7a946jj6i , |
| 1h-imidazolium,2-[2-[4-(dimethylamino)phenyl]diazenyl]-1,3-dimethyl-, chloride (1:1) |
| ci basic red 51 |
| ruby red |
| 1h-imidazolium, 2-[2-[4-(dimethylamino)phenyl]diazenyl]-1,3-dimethyl-, chloride (1:1) |
| vibracolor ruby red |
| 2-[2-[4-(dimethylamino)phenyl]diazenyl]-1,3-dimethyl-1h-imidazolium chloride (1:1) |
| 1016649-33-4 |
| 2-(4-(dimethylamino-phenylazo)-1,3-dimethyl-1,3-dimethyl-3h-imidazol- 1-ium chloride |
| 1h-imidazolium, 2-[(1e)-2-[4-(dimethylamino)phenyl]diazenyl]-1,3-dimethyl-, chloride (1:1) |
| basic red 51 [inci] |
| colorex br51 |
| SCHEMBL334242 |
| SCHEMBL334243 |
| 1h-imidazolium, 2-[[4-(dimethylamino)phenyl]azo]-1,3-dimethyl-, chloride |
| 2-[[4-(dimethylamino)phenyl]azo]-1,3-dimethyl-1h-imidazolium chloride |
| c.i. basic red 51 |
| J-004845 |
| DTXSID80874049 |
| 2-[2-[4-(dimethylamino)phenyl]diazenyl]-1,3-dimethyl-1h-imidazolium chloride |
| AS-17151 |
| Q27273724 |
| basicred51 |
| 4-[(1,3-dimethylimidazol-1-ium-2-yl)diazenyl]-n,n-dimethylaniline;chloride |
| 1h-imidazolium, 2-[[4-(dimethylamino)phenyl]azo]-1,3-dimethyl-, chloride (9ci); 2-[2-[4-(dimethylamino)phenyl]diazenyl]-1,3-dimethyl-1h-imidazolium chloride (1:1) |
| AKOS037643593 |
| 2-{2-[4-(dimethylamino)phenyl]diazen-1-yl}-1,3-dimethyl-1h-imidazol-3-ium chloride |
| mip red 2985 |
| rosso di base 51 |
| rojo basico 51 |
| vermelho basico 51 |
| rouge de base 51 |
Research Excerpts
Toxicity
| Excerpt | Reference | Relevance |
|---|---|---|
| " In this study, we investigated the toxic effects of two hair dyes, Basic Red 51 (BR51) and Basic Brown 17 (BB17), which are temporary dyes of the azo group (R-N=N-R'), used in the composition of the black hair dye." | ( Cytotoxic and genotoxic effects of two hair dyes used in the formulation of black color. Fernandes, TC; Marin-Morales, MA; Suares-Rocha, P; Tafurt-Cardona, Y, 2015) | 0.65 |
| " Degradation of ERY by light prevented all toxic effects previously observed, suggesting a cheap, fast and easy alternative treatment of effluents containing this natural dye." | ( Toxicity of dyes to zebrafish at the biochemical level: Cellular energy allocation and neurotoxicity. Abe, FR; Gravato, C; Oliveira, DP; Soares, AMVM, 2018) | 0.48 |
| " The toxic mode of action of Basic Blue 99 seems to be the induction of cell death, without genotoxic effects, but while the necrotic pathway is observed in HaCaT monolayer cell culture, was apoptosis seen in the Equivalent Human Epidermis (EHE) model." | ( Immortalized equivalent human epidermis as a platform to evaluation hair dyes toxicity: Efficiency comparison between 3D and monolayer culture. Dorta, DJ; Maria-Engler, SS; Mini, CA; Oliveira, DP, 2020) | 0.56 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (9)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 33.25
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (33.25) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||