| Assay ID | Title | Year | Journal | Article |
|---|
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6
| A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | | | |
| AID1628684 | Binding affinity to GST-tagged PLK3 PBD (335 to 646 residues) (unknown origin) by NT-647 dye-based microscale thermophoresis analysis | 2016 | Journal of medicinal chemistry, Aug-11, Volume: 59, Issue:15
| Discovery of Novel Polo-Like Kinase 1 Polo-Box Domain Inhibitors to Induce Mitotic Arrest in Tumor Cells. |
| AID1331795 | Binding affinity to NT-647 labeled PLK1 polo-box domain (unknown origin) expressed in Escherichia coli Rosetta (DE3) by microscale thermophoresis based fluorescence assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Identification of acylthiourea derivatives as potent Plk1 PBD inhibitors. |
| AID1628701 | Induction of mitotic arrest in human HeLa cells assessed as 4N DNA cells at 100 uM after 24 hrs by propidium iodide staining-based FACS analysis relative to control | 2016 | Journal of medicinal chemistry, Aug-11, Volume: 59, Issue:15
| Discovery of Novel Polo-Like Kinase 1 Polo-Box Domain Inhibitors to Induce Mitotic Arrest in Tumor Cells. |
| AID1628680 | Binding affinity to GST-tagged PLK1 PBD H538A mutant (unknown origin) by NT-647 dye-based microscale thermophoresis analysis | 2016 | Journal of medicinal chemistry, Aug-11, Volume: 59, Issue:15
| Discovery of Novel Polo-Like Kinase 1 Polo-Box Domain Inhibitors to Induce Mitotic Arrest in Tumor Cells. |
| AID1628682 | Binding affinity to GST-tagged PLK1 PBD (327 to 603 residues) (unknown origin) by NT-647 dye-based microscale thermophoresis analysis | 2016 | Journal of medicinal chemistry, Aug-11, Volume: 59, Issue:15
| Discovery of Novel Polo-Like Kinase 1 Polo-Box Domain Inhibitors to Induce Mitotic Arrest in Tumor Cells. |
| AID1874287 | Inhibition of 5-carboxyfluorescein-GPMQTSpTPKNG-OH peptide binding to C-terminal 6His-tagged human PLK2 (355 to 685 residues) PBD expressed in Rosetta BL21 (DE3) cells preincubated for 1 hrs with compound followed by peptide addition and measured immediat | 2022 | Journal of medicinal chemistry, 08-11, Volume: 65, Issue:15
| Polo-like Kinase 1 Inhibitors in Human Cancer Therapy: Development and Therapeutic Potential. |
| AID1874288 | Inhibition of 5-carboxyfluorescein-GPLATSpTPKNG-OH peptide binding to N-terminal MBP-tagged human PLK3 (335 to 646 residues) PBD expressed in Rosetta BL21 (DE3) cells preincubated for 1 hrs with compound followed by peptide addition and measured immediate | 2022 | Journal of medicinal chemistry, 08-11, Volume: 65, Issue:15
| Polo-like Kinase 1 Inhibitors in Human Cancer Therapy: Development and Therapeutic Potential. |
| AID1628686 | Binding affinity to GST-tagged PLK1 PBD W414A mutant (unknown origin) by NT-647 dye-based microscale thermophoresis analysis | 2016 | Journal of medicinal chemistry, Aug-11, Volume: 59, Issue:15
| Discovery of Novel Polo-Like Kinase 1 Polo-Box Domain Inhibitors to Induce Mitotic Arrest in Tumor Cells. |
| AID1331796 | Inhibition of 5-FAM-DPPLHSpTAI-OH binding to PLK1 polo-box domain (unknown origin) expressed in Escherichia coli Rosetta (DE3) after 1 hr by fluorescence polarization assay | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Identification of acylthiourea derivatives as potent Plk1 PBD inhibitors. |
| AID1874286 | Inhibition of 5-carboxyfluoresceinGPMQSpTPLNG-OH peptide binding to human PLK1 (326 to 603 residues) PBD expressed in Rosetta BL21 (DE3) cells preincubated for 1 hrs with compound followed by peptide addition and measured immediately by fluorescence polar | 2022 | Journal of medicinal chemistry, 08-11, Volume: 65, Issue:15
| Polo-like Kinase 1 Inhibitors in Human Cancer Therapy: Development and Therapeutic Potential. |
| AID1628685 | Binding affinity to GST-tagged PLK1 PBD K540A mutant (unknown origin) by NT-647 dye-based microscale thermophoresis analysis | 2016 | Journal of medicinal chemistry, Aug-11, Volume: 59, Issue:15
| Discovery of Novel Polo-Like Kinase 1 Polo-Box Domain Inhibitors to Induce Mitotic Arrest in Tumor Cells. |
| AID1628683 | Binding affinity to GST-tagged PLK2 PBD (355 to 685 residues) (unknown origin) by NT-647 dye-based microscale thermophoresis analysis | 2016 | Journal of medicinal chemistry, Aug-11, Volume: 59, Issue:15
| Discovery of Novel Polo-Like Kinase 1 Polo-Box Domain Inhibitors to Induce Mitotic Arrest in Tumor Cells. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |