Compounds > disperse orange 1
Page last updated: 2024-11-05

disperse orange 1

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Disperse Orange 1, also known as C.I. Solvent Orange 1, is an organic dye belonging to the azo dye family. It is a bright orange powder that is soluble in organic solvents like toluene and xylene. It is used in various applications, including dyeing synthetic fibers like polyester and nylon, as well as in printing inks and paints. The synthesis of Disperse Orange 1 involves the diazotization of 4-aminoazobenzene followed by coupling with N,N-dimethylaniline. This dye is known for its excellent color fastness, making it suitable for applications where color stability is crucial. It has been studied extensively for its potential environmental impacts, particularly its toxicity to aquatic organisms. Research is ongoing to develop alternative dyes with improved environmental profiles.'

Cross-References

ID SourceID
PubMed CID17414
SCHEMBL ID769328
MeSH IDM0555336

Synonyms (61)

Synonym
benzenamine, 4-[(4-nitrophenyl)azo]-n-phenyl-
disperse orange 1
acetate orange 5r
benzenamine, 4-((4-nitrophenyl)azo)-n-phenyl-
miketon fast orange 5r
diphenylamine, 4-((p-nitrophenyl)azo)-
dispersol printing orange a
celliton fast orange 5r
brn 0758695
acetoquinone light orange 4rl
reliton orange 5r
vonteryl red 4g
ci 11080
supracet scarlet 2g
navilene orange 5r
c.i. disperse orange 1
4-((4-nitrophenyl)azo)-n-phenylaniline
dispersol fast orange a
disperse orange 5r
setacyl scarlet p-2g
4-((p-nitrophenyl)azo)diphenylamine
palanil orange 5r
serisol orange 5r
dispersol orange a
hsdb 5535
diacelliton fast orange r
resolin orange 5r
setacyl scarlet 2gn
cilla fast orange 5r
einecs 219-954-6
celliton discharge orange 5rl
4-anilino-4'-nitroazobenzene
disperse orange 1, dye content ~15 %
2581-69-3
4-[(4-nitrophenyl)diazenyl]-n-phenylaniline
1592r4p97h ,
unii-1592r4p97h
ccris 9421
benzenamine, 4-(2-(4-nitrophenyl)diazenyl)-n-phenyl-
AKOS015903079
4-[2-(4-nitrophenyl)diazen-1-yl]-n-phenylaniline
4-nitro-4'-(phenylamino)azobenzene
4-(p-nitrophenylazo)diphenylamine
ci disperse orange 1 [hsdb]
4-(4-nitrophenylazo)diphenylamine
DTXSID7062536
SCHEMBL769328
YFVXLROHJBSEDW-UHFFFAOYSA-N
benzenamine, 4-[2-(4-nitrophenyl)diazenyl]-n-phenyl-
W-109803
4-[(4-nitrophenyl)azo]-n-phenylaniline
disperse orange 1, analytical standard
zirconiumsulfatetetrahydrate
do1 ,
Q5282570
STR05317
4-(4-nitrophenyl)azo-n-phenylaniline
4-((4-nitrophenyl)diazenyl)-n-phenylaniline
AKOS037655885
disperse orange 1 100 microg/ml in acetonitrile
benzenamine,4-[2-(4-nitrophenyl)diazenyl]-n-phenyl-;disperse orange 1

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Studies showed that some classes of dyes, mainly azo dyes and their by-products, exert adverse effects on humans and local biota, since the wastewater treatment systems and water treatment plants were found to be ineffective in removing the color and reducing toxicity of some dyes."( Hepatotoxicity assessment of the azo dyes disperse orange 1 (DO1), disperse red 1 (DR1) and disperse red 13 (DR13) in HEPG2 cells.
Boubriak, O; de Oliveira, DP; Ferraz, ER; Li, Z, 2012)		0.64
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (90.91)24.3611
2020's1 (9.09)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 30.81

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index30.81 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index5.10 (4.65)
Search Engine Demand Index36.71 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (30.81)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies2 (15.38%)4.05%
Observational0 (0.00%)0.25%
Other11 (84.62%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
azobenzene
azobenzene: photosensor molecule known to undergo reversible isomerization from trans to cis on illumination with photons of appropriate wavelength; RN given refers to cpd without isomeric designation; structure. (E)-azobenzene : The (E)-isomer of azobenzene.. (Z)-azobenzene : The (Z)-isomer of azobenzene.. azobenzene : A molecule whose structure comprises two phenyl rings linked by a N=N double bond; the parent compound of the azobenzene class of compounds.		2.0710azobenzenes
p-aminoazobenzene
p-Aminoazobenzene: Used in the form of its salts as a dye and as an intermediate in manufacture of Acid Yellow, diazo dyes, and indulines.. 4-(phenylazo)aniline : Azobenzene substituted at one of the 4-positions by an amino group. It has a role as a dye and an allergen.		2.1710
2-naphthylamine
2-Naphthylamine: A naphthalene derivative with carcinogenic action.. 2-naphthylamine : A naphthylamine carrying the amino group at position 2.		2.0710naphthylaminecarcinogenic agent
2-amino-4-methylphenol
2-amino-4-methylphenol: structure in first source		2.0710
4-nitroaniline
[no description available]		2.4820nitroanilinebacterial xenobiotic metabolite
4-phenylenediamine
4-phenylenediamine: agent hair dye responsible for contact dermatitis; RN given refers to parent cpd. 1,4-phenylenediamine : A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus.		2.5220phenylenediamineallergen;
dye;
hapten;
reagent
hydroxyhydroquinone
benzene-1,2,4-triol : A benzenetriol carrying hydroxy groups at positions 1, 2 and 4.		2.1510benzenetriolmouse metabolite
disperse orange 3
4-(4-nitrophenylazo)aniline : Azobenzene substituted at the phenyl 4-positions by an amino and a nitro group.		2.6920azobenzenes;
primary arylamine		allergen;
dye
1,12-dodecamethylenediamine
1,12-dodecamethylenediamine: RN given refers to parent cpd. dodecane-1,12-diamine : An alkane-alpha,omega-diamine that is dodecane substituted by amino groups at positions 1 and 12.		2.1110alkane-alpha,omega-diamine
dispersion yellow 3
Dispersion Yellow 3: used in carpet industry; river pollutant. 4-(2-hydroxy-5-methylphenylazo)acetanilide : An azo dye with a structure consisting of acetanilide substituted on the 4-position of the phenyl group with a 6-hydroxy-m-tolylazo group.		2.0710
disperse red 1
Disperse Red 1 : An azo dye with a structure consisting of nitrobenzene substituted on the 4-position of the phenyl group with a 4-[N-ethyl-N-(2-hydroxyethyl)]phenylazo group.		2.4720
disperse red 13
Disperse Red 13: structure in first source		2.4720
4-aminoacetanilide
[no description available]		2.0710
1,7-diaminoheptane
[no description available]		2.1110
disperse blue 35
disperse blue 35: not a single chemical cpd		2.610
glucuronic acid
Glucuronic Acid: A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.. D-glucuronic acid : The D-enantiomer of glucuronic acid.. D-glucopyranuronic acid : A D-glucuronic acid in cyclic pyranose form.		2.0710D-glucuronic acidalgal metabolite
metanil yellow
metanil yellow: RN given refers to parent cpd; structure. metanil yellow : An organic sodium salt having 3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonate as the counterion. Used in one variant of Masson's trichrome to stain collagen yellow in contrast to the red muscle, but is not in common used.		2.1710organic sodium salthistological dye
basic red 46
basic red 46: monoazoic dye used for acrylic textiles implicated in contact dermatitis		2.1710
ConditionIndicatedRelationship StrengthStudiesTrials
Allergic Contact Dermatitis
[description not available]		03.0540
Dermatitis, Allergic Contact
A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.		03.0540
Dermatitis, Occupational
A recurrent contact dermatitis caused by substances found in the work place.		02.1710
Hand Dermatosis
[description not available]		02.1710
Hand Dermatoses
Skin diseases involving the HANDS.		02.1710
Amyloid Deposits
[description not available]		02.2110
Acute Confusional Senile Dementia
[description not available]		02.2110
Innate Inflammatory Response
[description not available]		02.2110
Alzheimer Disease
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)		02.2110
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.		02.2110