| ID Source | ID |
|---|---|
| PubMed CID | 6786 |
| CHEMBL ID | 3181956 |
| CHEBI ID | 34678 |
| SCHEMBL ID | 50751 |
| MeSH ID | M0089076 |
| Synonym |
|---|
| BIDD:ER0642 |
| AKOS015839890 |
| phthalic acid di-n-hexyl ester |
| phthalic acid, dihexyl ester |
| dihexyl phthalate |
| di-n-hexyl phthalate |
| nsc4817 |
| nsc-4817 |
| wln: 6ovr bvo6 |
| 84-75-3 |
| 1, dihexyl ester |
| 1,2-benzenedicarboxylic acid, dihexyl ester |
| dihexyl 1,2-benzenedicarboxylate |
| ai3-04274 |
| dihexylester kyseliny ftalove [czech] |
| nsc 4817 |
| brn 1886839 |
| hexyl phthalate, 1,2- |
| 1,2-benzenedioic acid dihexyl ester |
| ai3-04274 (usda) |
| n-dihexyl phthalate |
| einecs 201-559-5 |
| di-n-hexylphthalate |
| bis(n-hexyl) phthalate |
| ccris 6192 |
| hsdb 4490 |
| di(n-hexyl)phthalate |
| 68515-50-4 |
| phthalic acid dihexyl ester |
| dihexyl benzene-1,2-dicarboxylate |
| P1344 |
| NCGC00247915-02 |
| NCGC00247915-01 |
| 42mah1qfg5 , |
| unii-42mah1qfg5 |
| 1,2-benzenedicarboxylic acid, 1,2-dihexyl ester |
| dihexylester kyseliny ftalove |
| cas-84-75-3 |
| dtxcid505068 |
| tox21_300165 |
| NCGC00254224-01 |
| dtxsid6025068 , |
| NCGC00259969-01 |
| tox21_202420 |
| 68610-82-2 |
| FT-0624940 |
| dihexyl phthalate [hsdb] |
| SCHEMBL50751 |
| CHEBI:34678 , |
| dihexylphthalate |
| KCXZNSGUUQJJTR-UHFFFAOYSA-N |
| CHEMBL3181956 |
| FT-0697120 |
| mfcd00043720 |
| dihexyl phthalate, analytical standard |
| S10762 |
| phthalic acid, bis-hexyl ester |
| phthalic acid, bis-hexyl ester 10 microg/ml in cyclohexane |
| F0001-2135 |
| Q26841288 |
| SY032083 |
| 1,2-dihexyl benzene-1,2-dicarboxylate |
| AS-56842 |
| CS-W011931 |
| EN300-1073399 |
| Class | Description |
|---|---|
| 2-hydroxyisophthalic acid | A hydroxybenzoic acid that is isophthalic acid in which the hydrogen at position 2 is substituted by a hydroxy group. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 41.8126 | 0.0025 | 41.7960 | 15,848.9004 | AID1347395; AID1347397 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 19.7250 | 0.0006 | 57.9133 | 22,387.1992 | AID1259378 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 16.3143 | 0.0010 | 22.6508 | 76.6163 | AID1224838; AID1224839; AID1224893 |
| progesterone receptor | Homo sapiens (human) | Potency | 48.1754 | 0.0004 | 17.9460 | 75.1148 | AID1346784; AID1346795 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 14.1847 | 0.0030 | 41.6115 | 22,387.1992 | AID1159552; AID1159555 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 22.3308 | 0.0008 | 17.5051 | 59.3239 | AID1159527 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 55.5927 | 0.0054 | 28.0263 | 1,258.9301 | AID1346982 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 35.6822 | 0.0002 | 29.3054 | 16,493.5996 | AID743069; AID743075; AID743078 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 25.0556 | 0.0010 | 24.5048 | 61.6448 | AID743215 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 58.8867 | 0.0007 | 23.0674 | 1,258.9301 | AID743122 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 13.6854 | 0.0016 | 28.0151 | 77.1139 | AID1224843; AID1224895 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 49.5470 | 0.0376 | 17.0823 | 61.1927 | AID1259364 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 31.2621 | 0.0023 | 19.5956 | 74.0614 | AID651631 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 6 (20.69) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 7 (24.14) | 29.6817 |
| 2010's | 8 (27.59) | 24.3611 |
| 2020's | 6 (20.69) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 2 (6.45%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 29 (93.55%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Article | Year |
|---|---|
| In utero exposure to dicyclohexyl and di-n-hexyl phthalate possess genotoxic effects on testicular cells of male rats after birth in the comet and TUNEL assays. Human & experimental toxicology, Volume: 33, Issue: 3 | 2014 |
| The toxic effect of phthalate esters on immune responses of giant freshwater prawn (Macrobrachium rosenbergii) via oral treatment. Aquatic toxicology (Amsterdam, Netherlands), Aug-30, Volume: 74, Issue: 2 | 2005 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |
| Article | Year |
|---|---|
| Comparative developmental toxicity evaluation of di- n-hexyl phthalate and dicyclohexyl phthalate in rats. Toxicology and industrial health, Volume: 33, Issue: 9 | 2017 |
| Dose-dependent alterations in gene expression and testosterone production in fetal rat testis after exposure to di-n-hexyl phthalate. Journal of applied toxicology : JAT, Volume: 33, Issue: 9 | 2013 |
| Reproductive effects of four phthalic acid esters in the mouse. Toxicology and applied pharmacology, Volume: 88, Issue: 2 | 1987 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |