| Assay ID | Title | Year | Journal | Article |
|---|
| AID706384 | Displacement of [125I]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counter | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID7691 | Inhibition against A2A-Adenosine Receptor of rat PC12 cell membranes (functional antagonist activity) | 2002 | Journal of medicinal chemistry, Aug-01, Volume: 45, Issue:16
| Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. |
| AID706382 | Selectivity ratio of Ki for human recombinant adenosine A1 receptor to Ki for human recombinant adenosine A3 receptor expressed in CHO cells | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID1687723 | Displacement of [3H]NECA from rat adenosine receptor A3 expressed in CHO cell membranes incubated for 60 mins by radioligand competition assay | | | |
| AID31696 | Inhibition against Adenosine A1 receptor of rat fat cell membranes (functional antagonist activity) | 2002 | Journal of medicinal chemistry, Aug-01, Volume: 45, Issue:16
| Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. |
| AID1871330 | Antagonist activity at adenosine A3 receptor (unknown origin) | 2022 | European journal of medicinal chemistry, Jan-05, Volume: 227 | Adenosine receptor antagonists: Recent advances and therapeutic perspective. |
| AID1687716 | Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes incubated for 90 mins by radioligand competition assay | | | |
| AID706386 | Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counter | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID1687719 | Displacement of [3H]MSX2 from adenosine receptor A2A in rat brain striatum membranes incubated for 30 mins by radioligand competition assay | | | |
| AID706389 | Displacement of [3H]CGS21680 from rat adenosine A2A receptor expressed in CHO cells after 60 mins by gamma counter | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID35023 | Binding affinity to the adenosine A2A receptor by displacement of [3H]CGS-21680 in rat brain striatal membrane | 2002 | Journal of medicinal chemistry, Aug-01, Volume: 45, Issue:16
| Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. |
| AID706377 | Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as blockade of Cl-IB-MECA-mediated inhibition of forskolin-stimulated [3H]cAMP accumulation by scintillation counter | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID706380 | Selectivity ratio of Ki for human recombinant adenosine A2A receptor to Ki for human recombinant adenosine A3 receptor expressed in CHO cells | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID706388 | Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in CHO cells after 60 mins by gamma counter | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID1687718 | Displacement of [3H]MSX2 from human adenosine receptor A2A expressed in HEK293 cell membranes incubated for 30 mins by radioligand competition assay | | | |
| AID34580 | Binding affinity against human recombinant Adenosine A3 receptor stably expressed in HEK293 cells by displacing [125I]AB-MECA radioligand | 2002 | Journal of medicinal chemistry, Aug-01, Volume: 45, Issue:16
| Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. |
| AID31858 | Binding affinity against Adenosine A1 receptor by displacing [3H]CHA radioligand in rat brain cortical membrane | 2002 | Journal of medicinal chemistry, Aug-01, Volume: 45, Issue:16
| Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. |
| AID1819795 | Binding affinity to mouse adenosine A3 receptor measured by radioligand binding assay | 2022 | ACS medicinal chemistry letters, Apr-14, Volume: 13, Issue:4
| Selective A |
| AID706387 | Displacement of [3H]CCPA from rat adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counter | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID1687720 | Displacement of [3H]PSB-603 from human adenosine receptor A2B expressed in CHO cell membranes incubated for 75 mins by radioligand competition assay | | | |
| AID607142 | Binding affinity to human recombinant A3 adenosine receptor by radioligand binding assay | 2011 | Journal of medicinal chemistry, Jul-28, Volume: 54, Issue:14
| New 2-heterocyclyl-imidazo[2,1-i]purin-5-one derivatives as potent and selective human A3 adenosine receptor antagonists. |
| AID7696 | Inhibition against A2B-Adenosine Receptor in mouse NIH 3T3 fibroblast cell membranes (functional antagonist activity) | 2002 | Journal of medicinal chemistry, Aug-01, Volume: 45, Issue:16
| Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. |
| AID1687722 | Displacement of [3H]PSB-11 from human adenosine receptor A3 expressed in CHO cell membranes incubated for 60 mins by radioligand competition assay | | | |
| AID1687717 | Displacement of [3H]CCPA from adenosine receptor A1 in rat brain cortex membranes incubated for 90 mins by radioligand competition assay | | | |
| AID1819796 | Binding affinity to human adenosine A3 receptor measured by radioligand binding assay | 2022 | ACS medicinal chemistry letters, Apr-14, Volume: 13, Issue:4
| Selective A |
| AID1819763 | Binding affinity to rat adenosine A3 receptor measured by radioligand binding assay | 2022 | ACS medicinal chemistry letters, Apr-14, Volume: 13, Issue:4
| Selective A |
| AID1345822 | Human A3 receptor (Adenosine receptors) | 2002 | Bioorganic & medicinal chemistry letters, Feb-11, Volume: 12, Issue:3
| [(3)H]8-Ethyl-4-methyl-2-phenyl-(8R)-4,5,7,8-tetrahydro-1H-imidazo[2,1-i]-purin-5-one ([(3)H]PSB-11), a novel high-affinity antagonist radioligand for human A(3) adenosine receptors. |
| AID1345690 | Rat A2A receptor (Adenosine receptors) | 2003 | Bioorganic & medicinal chemistry, Feb-06, Volume: 11, Issue:3
| 2-Phenylimidazo[2,1-i]purin-5-ones: structure-activity relationships and characterization of potent and selective inverse agonists at Human A3 adenosine receptors. |
| AID1345822 | Human A3 receptor (Adenosine receptors) | 2003 | Bioorganic & medicinal chemistry, Feb-06, Volume: 11, Issue:3
| 2-Phenylimidazo[2,1-i]purin-5-ones: structure-activity relationships and characterization of potent and selective inverse agonists at Human A3 adenosine receptors. |
| AID1345735 | Mouse A2B receptor (Adenosine receptors) | 2002 | Journal of medicinal chemistry, Aug-01, Volume: 45, Issue:16
| Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. |
| AID1345685 | Human A1 receptor (Adenosine receptors) | 2003 | Bioorganic & medicinal chemistry, Feb-06, Volume: 11, Issue:3
| 2-Phenylimidazo[2,1-i]purin-5-ones: structure-activity relationships and characterization of potent and selective inverse agonists at Human A3 adenosine receptors. |
| AID1345630 | Rat A1 receptor (Adenosine receptors) | 2003 | Bioorganic & medicinal chemistry, Feb-06, Volume: 11, Issue:3
| 2-Phenylimidazo[2,1-i]purin-5-ones: structure-activity relationships and characterization of potent and selective inverse agonists at Human A3 adenosine receptors. |
| AID1345618 | Human A2A receptor (Adenosine receptors) | 2003 | Bioorganic & medicinal chemistry, Feb-06, Volume: 11, Issue:3
| 2-Phenylimidazo[2,1-i]purin-5-ones: structure-activity relationships and characterization of potent and selective inverse agonists at Human A3 adenosine receptors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |