| Assay ID | Title | Year | Journal | Article |
|---|
| AID1345685 | Human A1 receptor (Adenosine receptors) | 2006 | Nature reviews. Drug discovery, Mar, Volume: 5, Issue:3
| Adenosine receptors as therapeutic targets. |
| AID1345618 | Human A2A receptor (Adenosine receptors) | 2006 | Nature reviews. Drug discovery, Mar, Volume: 5, Issue:3
| Adenosine receptors as therapeutic targets. |
| AID1345822 | Human A3 receptor (Adenosine receptors) | 2006 | Nature reviews. Drug discovery, Mar, Volume: 5, Issue:3
| Adenosine receptors as therapeutic targets. |
| AID1345721 | Human A2B receptor (Adenosine receptors) | 2006 | Nature reviews. Drug discovery, Mar, Volume: 5, Issue:3
| Adenosine receptors as therapeutic targets. |
| AID387272 | Displacement of [3H]R-PIA form human adenosine A2A receptor expressed in HEK cells | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Selective A(3) adenosine receptor antagonists derived from nucleosides containing a bicyclo[3.1.0]hexane ring system. |
| AID676070 | Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production at 10 uM incubated for 30 mins prior to forskolin-stimulation measured after 15 mins by enzyme immunoassay re | 2012 | Journal of medicinal chemistry, May-24, Volume: 55, Issue:10
| Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions. |
| AID676068 | Displacement of [3H]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting | 2012 | Journal of medicinal chemistry, May-24, Volume: 55, Issue:10
| Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions. |
| AID706382 | Selectivity ratio of Ki for human recombinant adenosine A1 receptor to Ki for human recombinant adenosine A3 receptor expressed in CHO cells | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID1324481 | Antagonist activity at human 5-HT2BR expressed in Flp-In HEK cells assessed as inhibition of 5-HT-induced calcium mobilization preincubated for 5 to 10 mins followed 5-HT addition by Fluo-4 dye based FLIPR assay | | | |
| AID331876 | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyl-uronamide from mouse recombinant adenosine A1 receptor expressed in HEK293 cells | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID706380 | Selectivity ratio of Ki for human recombinant adenosine A2A receptor to Ki for human recombinant adenosine A3 receptor expressed in CHO cells | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID331882 | Displacement of radioligand from rat adenosine A1 receptor | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID676078 | Selectivity ratio of EC50 for human adenosine A2B receptor to EC50 for human adenosine A3 receptor | 2012 | Journal of medicinal chemistry, May-24, Volume: 55, Issue:10
| Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions. |
| AID331887 | Selectivity for mouse adenosine A3 receptor over mouse adenosine A1 receptor | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID706385 | Displacement of [125I]I-AB-MECA from human rat adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counter | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID239011 | Inhibition of [3H]R-PIA binding to human Adenosine A1 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Mar-24, Volume: 48, Issue:6
| (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists. |
| AID387270 | Displacement of [3H]CCPA form human adenosine A1 receptor expressed in CHO cells | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Selective A(3) adenosine receptor antagonists derived from nucleosides containing a bicyclo[3.1.0]hexane ring system. |
| AID706384 | Displacement of [125I]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counter | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID676064 | Displacement of [3H]R-PIA from human recombinant adenosine A1 receptor expressed in CHO cells after 60 mins by liquid scintillation counting | 2012 | Journal of medicinal chemistry, May-24, Volume: 55, Issue:10
| Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions. |
| AID239092 | Inhibition of [125I]-AB-MECA binding to human Adenosine A3 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Mar-24, Volume: 48, Issue:6
| (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists. |
| AID331881 | Displacement of radioligand from human adenosine A3 receptor expressed in CHO cells | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID251590 | Relative activation of human Adenosine A3 receptor expressed in CHO cells at 10 uM treatment compared to 10 uM Cl-IB-MECA | 2005 | Journal of medicinal chemistry, Mar-24, Volume: 48, Issue:6
| (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists. |
| AID706388 | Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in CHO cells after 60 mins by gamma counter | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID251589 | Relative activation of human Adenosine A2B receptor at 10 uM treatment compared to 10 uM Cl-IB-MECA | 2005 | Journal of medicinal chemistry, Mar-24, Volume: 48, Issue:6
| (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists. |
| AID676066 | Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting | 2012 | Journal of medicinal chemistry, May-24, Volume: 55, Issue:10
| Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions. |
| AID387274 | Displacement of [3H]CGS21680 form human adenosine A3 receptor expressed in CHO cells | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Selective A(3) adenosine receptor antagonists derived from nucleosides containing a bicyclo[3.1.0]hexane ring system. |
| AID331884 | Displacement of radioligand from rat A3 adenosine receptor | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID331888 | Selectivity for human adenosine A3 receptor over human adenosine A1 receptor | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID331880 | Displacement of radioligand from human adenosine A2A receptor expressed in HEK293 cells | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID331877 | Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-N-ethylcarboxamidoadenosine from mouse recombinant adenosine A2A receptor expressed in HEK293 cells | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID331878 | Displacement of [125I]N6-(-amino-3-iodobenzyl)adenosine-5'-N-methyl-uronamide from mouse recombinant adenosine A3 receptor expressed in HEK293 cells | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID387278 | Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as forskolin-stimulated cAMP accumulation at 10 uM relative to NECA | 2008 | Bioorganic & medicinal chemistry, Sep-15, Volume: 16, Issue:18
| Selective A(3) adenosine receptor antagonists derived from nucleosides containing a bicyclo[3.1.0]hexane ring system. |
| AID331883 | Displacement of radioligand from rat adenosine A2A receptor | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID331879 | Displacement of radioligand from human adenosine A1 receptor expressed in CHO cells | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID331891 | Activation of human adenosine A2B receptor | 2008 | Bioorganic & medicinal chemistry letters, May-01, Volume: 18, Issue:9
| Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. |
| AID706386 | Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counter | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. |
| AID239113 | Inhibition of [3H]-CGS- 21680 binding to human Adenosine A2A receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Mar-24, Volume: 48, Issue:6
| (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists. |
| AID239053 | Inhibition of [125I]AB-MECA binding to rat Adenosine A3 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Mar-24, Volume: 48, Issue:6
| (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |